The Physiology and Pathology of the Cerebellum was first published in 1958. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions. The development of electrical methods of recording activity in the nervous system has greatly augmented our knowledge of cerebellar physiology. Now, for the first time in a single volume, this new information has been related to facts derived from older methods of investigation. Previously unpublished reports of experiments conducted at the Institute of Physiology, University of Pisa, Italy, also are included. The authors, an American clinical neurologist and an Italian neuro-physiologist, have collaborated to provide a comprehensive review of cerebellar physiology and a survey of the clinical symptomatology of cerebellar disorders and the pathology of the cerebellum. In Part I, devoted to the physiology, the authors review the literature completely and place it in proper relation to the latest developments in this field. There are chapters on this history of cerebellar physiology, ablation experiments, stimulation experiments, electro-physiological experiments, the relations between the cerebellum and other central nervous structures, developmental physiology, and the functions of the cerebellum, considered generally. Part II is devoted to the human cerebellum as studied in the clinic. Where anatomical and physiological observation may shed light upon obscure clinical findings, the laboratory data are related to the clinical investigations. The disorders and diseases affecting the cerebellum are systemically reviewed. The book is illustrated with 61 halftones and 124 line drawings.
Many historically and artistically important masonry buildings of the world’s architecturalheritageareindireneedofmaintenanceandrestoration.Inorder tooptimizesuchoperationsintermsofcost-e?ectiveness,architecturalimpact andstatice?ectiveness,accuratemodelsofthestructuralbehaviorofmasonry constructions are invaluable. The ultimate aim of such modeling is to obtain important information, such as the stress ?eld, and to estimate the extent of cracking and its evolution when the structure is subjected to variations in both boundary and loading conditions. Although masonry has been used in building for centuries, it is only - centlythatconstitutivemodelsandcalculationtechniqueshavebeenavailable that enable realistic description of the static behavior of structures made of this heterogeneous material whose response to tension is fundamentally d- ferent from that to compression. Important insights on the mechanical behavior of masonry arches and vaults come from as far back as Leonardo [10], Hooke [58], Poleni [92] and many other authors (see [47], [9] and [10] for detailed references). Castigliano, in his famous paper on the Mosca bridge [23], and Signorini, in his studies on masonry beams [97], [98], showed both the possibility and necessity of taking into account the weak tensile strength of masonry material.
Neurotransmitters and Anterior Pituitary Function discusses research findings on neurotransmitter-neurohormone interactions in the control of the anterior pituitary. This book contains five chapters that specifically tackle the most salient constituents of the neural-endocrine communication system in mammals. This book deals first with the biochemistry, physiology, and pharmacology of proved or putative neurotransmitters, as well as some of the techniques used for determining their synthesis or turnover in the central nervous system (CNS) of experimental animals or in man. These topics are followed by a discussion on the principal functions of the most well-known neurotransmitter containing neurons based on sophisticated techniques for neurotransmitter measurements. A chapter highlights both traditional and a vast series of developed drugs that affect both neurotransmitter and neuroendocrine function. Discussions then shift to the experimental evidence on pituitary function control by the brain through releasing and inhibiting hormones secreted by hypothalamic neuroendocrine cells; the chemical isolation, identification, and synthesis of hypothalamic neurohormones; and concepts of their mechanism of action at the level of the pituitary cells. This text further explores the role of specific brain neurotransmitters in controlling pituitary hormone secretions in both experimental animals and in man and the possible CNS site(s) where neurotransmitters and neurohormones interact for the control of anterior pituitary secretion. The concluding chapter describes the actual or potential application of neuropharmacologic approaches to the diagnosis of and therapy for specific disorders of neuroendocrine function. Clinical neuroendocrinologists and researchers and students in neuroendocrinology, neurobiology, neuropharmacology, neurophysiology, and psychiatry will find this book invaluable.
The Physiology and Pathology of the Cerebellum was first published in 1958. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the original University of Minnesota Press editions. The development of electrical methods of recording activity in the nervous system has greatly augmented our knowledge of cerebellar physiology. Now, for the first time in a single volume, this new information has been related to facts derived from older methods of investigation. Previously unpublished reports of experiments conducted at the Institute of Physiology, University of Pisa, Italy, also are included. The authors, an American clinical neurologist and an Italian neuro-physiologist, have collaborated to provide a comprehensive review of cerebellar physiology and a survey of the clinical symptomatology of cerebellar disorders and the pathology of the cerebellum. In Part I, devoted to the physiology, the authors review the literature completely and place it in proper relation to the latest developments in this field. There are chapters on this history of cerebellar physiology, ablation experiments, stimulation experiments, electro-physiological experiments, the relations between the cerebellum and other central nervous structures, developmental physiology, and the functions of the cerebellum, considered generally. Part II is devoted to the human cerebellum as studied in the clinic. Where anatomical and physiological observation may shed light upon obscure clinical findings, the laboratory data are related to the clinical investigations. The disorders and diseases affecting the cerebellum are systemically reviewed. The book is illustrated with 61 halftones and 124 line drawings.
This book attempts to clarify a relatively new problem in the area of brain-behavior relationships, namely the link between emotions and hemispheric specialization. The contributions by leading specialists integrate theoretical models of emotions in normal subjects with results of experimental investigations conducted in patients with unilateral brain lesions. The communicative aspects of emotions and the inner experience of emotions as well as the concomitant autonomous changes are separately investigated and discussed.
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