Kleine Moleküle für Einsteiger: Dieser für Lehre und Selbststudium gleichermaßen geeignete Band behandelt den computergestützten Entwurf von Wirkstoffen, Enzyminhibitoren, Sonden und Markern für Biomoleküle und führt den Leser bis zum ersten eigenen De-Novo-Design eines funktionellen Moleküls. Gestützt auf lange Erfahrung im Molecular-Modeling-Umfeld erläutern die Autoren, welche Fragen mit den beschriebenen Methoden beantwortet werden können (und welche nicht).
A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on its scientific merit alone.
This exploration of the relation between periods and transcendental numbers brings Baker's theory of linear forms in logarithms into its most general framework, the theory of 1-motives. Written by leading experts in the field, it contains original results and finalises the theory of linear relations of 1-periods, answering long-standing questions in transcendence theory. It provides a complete exposition of the new theory for researchers, but also serves as an introduction to transcendence for graduate students and newcomers. It begins with foundational material, including a review of the theory of commutative algebraic groups and the analytic subgroup theorem as well as the basics of singular homology and de Rham cohomology. Part II addresses periods of 1-motives, linking back to classical examples like the transcendence of π, before the authors turn to periods of algebraic varieties in Part III. Finally, Part IV aims at a dimension formula for the space of periods of a 1-motive in terms of its data.
This book consists of the notes from the seminar Bonn/ Wuppertal 1983/ 84 on Arithmetic Geometry. It contains a proof for the Mordell conjecture and may be useful as an introduction to Arakelov's point of view in diophantine geometry. The third edition includes an appendix in which a detailed survey on the spectacular recent developments in arithmetic algebraic geometry is given. These beautiful new results have their roots in the material covered by this book.
Kleine Moleküle für Einsteiger: Dieser für Lehre und Selbststudium gleichermaßen geeignete Band behandelt den computergestützten Entwurf von Wirkstoffen, Enzyminhibitoren, Sonden und Markern für Biomoleküle und führt den Leser bis zum ersten eigenen De-Novo-Design eines funktionellen Moleküls. Gestützt auf lange Erfahrung im Molecular-Modeling-Umfeld erläutern die Autoren, welche Fragen mit den beschriebenen Methoden beantwortet werden können (und welche nicht).
A brief history of drug design presented to make clear that there are fashions in this important field and that they change rather rapidly. This is due in part to the fact that the way that a new paradigm is accepted in a drug company often does not depend on its scientific merit alone.
This will help us customize your experience to showcase the most relevant content to your age group
Please select from below
Login
Not registered?
Sign up
Already registered?
Success – Your message will goes here
We'd love to hear from you!
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.