This book provides an up-to-date presentation of homogeneous pseudo-Riemannian structures, an essential tool in the study of pseudo-Riemannian homogeneous spaces. Benefiting from large symmetry groups, these spaces are of high interest in Geometry and Theoretical Physics. Since the seminal book by Tricerri and Vanhecke, the theory of homogeneous structures has been considerably developed and many applications have been found. The present work covers a gap in the literature of more than 35 years, presenting the latest contributions to the field in a modern geometric approach, with special focus on manifolds equipped with pseudo-Riemannian metrics. This unique reference on the topic will be of interest to researchers working in areas of mathematics where homogeneous spaces play an important role, such as Differential Geometry, Global Analysis, General Relativity, and Particle Physics.
Maintenance of the information embedded in the genomic DNA sequence is essential for life. DNA polymerases play pivotal roles in the complex processes that maintain genetic integrity. Besides their tasks in vivo, DNA polymerases are the workhorses in numerous biotechnology applications such as the polymerase chain reaction (PCR), cDNA cloning, genome sequencing, nucleic acids-based diagnostics and in techniques to analyze ancient and otherwise damaged DNA. Moreover, some diseases are related to DNA polymerase defects, and chemotherapy through inhibition of DNA polymerases is used to fight HIV, Herpes and Hepatitis B and C infections. We have recently witnessed the discovery of an abundance of novel DNA polymerases in viruses, bacteria, archaea and eukaryotes with specialized properties whose physiological functions are only beginning to be understood. This book summarizes the current knowledge of these fascinating enzymes. It is intended for a wide audience from basic scientists, to diagnostic laboratories and to clinicians who seek a better understanding of these fascinating enzymes.
This book provides an up-to-date presentation of homogeneous pseudo-Riemannian structures, an essential tool in the study of pseudo-Riemannian homogeneous spaces. Benefiting from large symmetry groups, these spaces are of high interest in Geometry and Theoretical Physics. Since the seminal book by Tricerri and Vanhecke, the theory of homogeneous structures has been considerably developed and many applications have been found. The present work covers a gap in the literature of more than 35 years, presenting the latest contributions to the field in a modern geometric approach, with special focus on manifolds equipped with pseudo-Riemannian metrics. This unique reference on the topic will be of interest to researchers working in areas of mathematics where homogeneous spaces play an important role, such as Differential Geometry, Global Analysis, General Relativity, and Particle Physics.
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