This two-volume set provides essential information on the general princi-ples of target organ toxicity. Pharmacokinetics, metabolic activation and key defense mechanisms, excretion, species variation, and tissue-specific biochemistry are explored comprehensively. These general principles are then illustrated using specific examples of toxicity to different target organs and systems. DNA modifi-cation and repair in tumor induction, and specificity in tumor initiation are also examined. Of primary interest to toxicologist, pharma-cologists, biochemists, and environmental toxicologists.
Gerald K. Stone has collected books about Canadian Jewry since the early 1980s. This volume is a descriptive catalog of his Judaica collection, comprising nearly 6,000 paper or electronic documentary resources in English, French, Yiddish, and Hebrew. Logically organized, indexed, and selectively annotated, the catalog is broad in scope, covering Jewish Canadian history, biography, religion, literature, the Holocaust, antisemitism, Israel and the Middle East, and more. An introduction by Richard Menkis discusses the significance of the Catalog and collecting for the study of the Jewish experience in Canada. An informative bibliographical resource, this book will be of interest to scholars and students of Canadian and North American Jewish studies.
Contents: Recursive Enumerability and the Jump Operator; On the Degrees Less Than 0'; A Simple Set Which Is Not Effectively Simple; The Recursively Enumerable Degrees Are Dense; Metarecursive Sets (with G Kreisel); Post's Problem, Admissible Ordinals and Regularity; On a Theorem of Lachlan and Marlin; A Minimal Hyperdegree (with R O Gandy); Measure-Theoretic Uniformity in Recursion Theory and Set Theory; Forcing with Perfect Closed Sets; Recursion in Objects of Finite Type; The a-Finite Injury Method (with S G Simpson); Remarks Against Foundational Activity; Countable Admissible Ordinals and Hyperdegrees; The 1-Section of a Type n Object; The k-Section of a Type n Object; Post's Problem, Absoluteness and Recursion in Finite Types; Effective Bounds on Morley Rank; On the Number of Countable Models; Post's Problem in E-Recursion; The Limits of E-Recursive Enumerability; Effective Versus Proper Forcing.
Why an organization's response to digital disruption should focus on people and processes and not necessarily on technology. Digital technologies are disrupting organizations of every size and shape, leaving managers scrambling to find a technology fix that will help their organizations compete. This book offers managers and business leaders a guide for surviving digital disruptions—but it is not a book about technology. It is about the organizational changes required to harness the power of technology. The authors argue that digital disruption is primarily about people and that effective digital transformation involves changes to organizational dynamics and how work gets done. A focus only on selecting and implementing the right digital technologies is not likely to lead to success. The best way to respond to digital disruption is by changing the company culture to be more agile, risk tolerant, and experimental. The authors draw on four years of research, conducted in partnership with MIT Sloan Management Review and Deloitte, surveying more than 16,000 people and conducting interviews with managers at such companies as Walmart, Google, and Salesforce. They introduce the concept of digital maturity—the ability to take advantage of opportunities offered by the new technology—and address the specifics of digital transformation, including cultivating a digital environment, enabling intentional collaboration, and fostering an experimental mindset. Every organization needs to understand its “digital DNA” in order to stop “doing digital” and start “being digital.” Digital disruption won't end anytime soon; the average worker will probably experience numerous waves of disruption during the course of a career. The insights offered by The Technology Fallacy will hold true through them all. A book in the Management on the Cutting Edge series, published in cooperation with MIT Sloan Management Review.
Counseling Addicted Families, Second Edition, is an up-to-date treatment manual that fosters lasting change for families dealing with addiction and addictive disorders. Focused around the clinically esteemed Sequential Family Addictions Model, the book guides counselors through the principles of how to "progressively sequence" a client family during their change process, and explores how family counseling theories and interventions can be applied in treatment settings. This second edition aligns with the DSM-5 Substance Use Disorder criteria and terminology and includes new sections on neuroscience and cutting-edge drug detection assessment methods. Both experienced and entry-level counselors will appreciate how the Model improves their clinical skills and knowledge to address the idiosyncratic needs of each individual family system and create healthy systemic change.
A collection of forty-three primary sources, ranging from contributions to scholarly journals to newspaper articles and first person accounts. An indispensable supplement to any course in abnormal or clinical psychology. Articles represent current research findings in psychopathology and indicate the direction of new research. The editors provide introductory material for each article.
Sorin also shows how the large migration of Jews from Russia and Eastern Europe in the late nineteenth century made a lasting impact on how other Americans imagine, understand, and relate to Jewish Americans and their cultural contributions today.
Ignite your students’ excitement about behavioral neuroscience with Brain & Behavior: An Introduction to Behavioral Neuroscience, Fifth Edition by best-selling author Bob Garrett and new co-author Gerald Hough. Garrett and Hough make the field accessible by inviting students to explore key theories and scientific discoveries using detailed illustrations and immersive examples as their guide. Spotlights on case studies, current events, and research findings help students make connections between the material and their own lives. A study guide, revised artwork, new animations, and an interactive eBook stimulate deep learning and critical thinking. A Complete Teaching & Learning Package Contact your rep to request a demo, answer your questions, and find the perfect combination of tools and resources below to fit your unique course needs. SAGE Premium Video Stories of Brain & Behavior and Figures Brought to Life videos bring concepts to life through original animations and easy-to-follow narrations. Watch a sample. Interactive eBook Your students save when you bundle the print version with the Interactive eBook (Bundle ISBN: 978-1-5443-1607-9), which includes access to SAGE Premium Video and other multimedia tools. Learn more. SAGE coursepacks SAGE coursepacks makes it easy to import our quality instructor and student resource content into your school’s learning management system (LMS). Intuitive and simple to use, SAGE coursepacks allows you to customize course content to meet your students’ needs. Learn more. SAGE edge This companion website offers both instructors and students a robust online environment with an impressive array of teaching and learning resources. Learn more. Study Guide The completely revised Study Guide offers students even more opportunities to practice and master the material. Bundle it with the core text for only $5 more! Learn more.
The growth of neurochemistry, molecular biology, and biochemical genetics has led to a burgeoning of new information relevant to the pathogenesis of brain dysfunction. This explosion of exciting new information is crying out for collation and meaningful synthesis. In its totality, it defies systematic summa tion, and, of course, no one author can cope. Thus invitations for contributions were given to various experts in areas which are under active investigation, of current neurological interest, and pregnant. Although this project is relatively comprehensive, by dint of size, other topics might have been included; the selection was solely my responsibility. I believe systematic summation a virtual impossibility-indeed, hardly worth the effort. The attempt to assemble all of the sections involved in a large treatise with mUltiple authors inevitably results in untoward delays due to the difference in the rate at which various authors work. Therefore, the following strategy has been adopted: multiple small volumes and a relatively flexible format, with publication in order of receipt and as soon as enough chapters are assembled to make publication practical and economical. In this way, the time lag between the ideas and their emergence in print is the shortest.
The Egalitarian Conscience pays tribute to the highly influential work of Professor G. A. Cohen. Professor Cohen is a philosopher of international stature and tremendous achievement, who has been vital to the flourishing of egalitarian political philosophy. He has a significant body of work spanning issues of Marxism and distributive justice, consistently characterized by original ideas and ingenious arguments. The high standard of rigour he sets for progressive thinkers,particularly himself, has been a source of inspiration for colleagues and students alike.The volume honours Professor Cohen with first-rate essays on a number of significant and fascinating topics, reflecting the wide-ranging themes of Professor Cohen's work, but united in their concern for questions of social justice, pluralism, equality, and moral duty. The contributors are scholars of international stature: Joshua Cohen, Jon Elster, Susan Hurley, Will Kymlicka, Derek Parfit, John Roemer, T. M. Scanlon, Samuel Scheffler, Hillel Steiner, and Jeremy Waldron. There is an afterwordby G. A. Cohen.
The Adoption and Safe Families Act (ASFA), which became law in 1997, elicited a major shift in federal policy and thinking toward child welfare, emphasizing children’s safety, permanency, and well-being over preserving their biological ties at all costs. The first edition of this volume was the earliest major social work textbook to map the field of child welfare after ASFA’s passage, detailing the practices, policies, programs, and research affected by the legislation’s new attitude toward care. This second edition highlights the continuously changing child welfare climate in the U.S., including content on the Fostering Connections Act of 2008. Gerald P. Mallon and Peg McCartt Hess have updated the text throughout, drawing from real world case examples, using data obtained from the national Child and Family Services Reviews and emerging empirically based practices. They have also added chapters addressing child welfare workforce issues, supervision, and research and evaluation. Divided into four sections—child and adolescent well-being, child and adolescent safety, permanency for children and adolescents, and systemic issues within services, policies, and programs—this newly edited volume provides a current understanding of family support and child protective services, risk assessment, substance and sexual abuse issues, domestic violence issues, guardianship, reunification, kinship and foster family care, adoption, and transitional living programs. Recognized scholars, practitioners, and policy makers also discuss meaningful engagement with families, particularly Latino families; health care for children and youth, including mental health care; effective practices with LGBT youth and their families; placement stability; foster parent recruitment and retention; and the challenges of working with immigrant children, youth, and families.
An A-Z listing of drugs by generic name. Each monograph summarizes the known and/or possible effects of the drug on the fetus. It also summarizes the known/possible passage of the drug into the human breast milk. A careful and exhaustive summarization of the world literature as it relates to drugs in pregnancy and lacation. Each monograph contains six parts: generic US name, Pharmacologic class, Risk factor, Fetal risk summary, Breast feeding summary, References
Guteks classic volume on the history of American education has been thoroughly revised and updated to provide a twenty-first-century perspective on the development of American educational institutions. Like earlier editions, the well-researched Third Edition employs a topical approach to examine the evolution of key institutions like the common school and the high school, as well as significant movements like progressive education, racial desegregation, and multiculturalism. Primary source readings enhance and reinforce chapter content and feature new writings from Benjamin Rush, Horace Mann, Maria Montessori, W. E. B. Du Bois, John Dewey, and Jane Addams. Two new chapters add depth to this comprehensive, richly illustrated work. Immigration, Multiculturalism, and Education examines the response of public schools to the education of immigrant children in the context of Americas industrialization and urbanization. This compelling addition also looks at the changing demographics of immigration and discusses the experiences and contributions of Hispanic Americans and Asian Americans. Progressive Education and John Dewey explores the origins of progressive education, the philosophies of John Dewey and other leading progressive educators, and this movements ongoing influence in American classrooms. The Third Editions topical organization lends itself to multiple uses in the classroom. Each chapter provides the historical foundation for the study of a contemporary topic in education, including the organization and structure of schools, the philosophy of education, early childhood education, curriculum and instruction, multicultural and bilingual education, and educational policy.
An exceptional opportunity is being missed. A chance to alleviate suffering and to achieve health care cost reductions for society is available, but is being ignored. There is an explosion of new knowledge about the emotional and intellectual development of children, and the causes and treatment of psychiatric disorders of children and adolescents. Research from diverse disciplines such as the developmental neurosciences, psychoanalysis, psychopharmacology, developmental psychology, and genetics propels us forward,. However, the effects of this new knowledge reach children and adolscents slowly, or not at all. The long history of neglect of the mental health of children and adolescents is now exaggurated by sudden, disruptive economic and political influences on mental health services for children and adolescents in most countries. Prevention and treatment of emotional and intellectual problems in childhood and adolescence have vastly improved, but utilization of these advantages lags behind. This disappointing incongruity stimulates a need to document our knowledge about these services and systems and to make it more broadly available. This is the primary aim of this new volume by a team of distinguished contributors. It reviews the causes and prevalences of psychiatric disorders in children and adolescents, the problem of health care financing for these services, the underutilization of these services, our current understanding of the outcomes of treatment, and the new models for both treatment and prevention. The book also provides a survey of current mental health services and sytems for children and adolescents in countries across the world. Information drawn from these multiple perspectives is has been used by a group of international experts to develop the Venice Declaration, providing specific guidelines for families, clinicians, administrators, and policy-makers who are concerned with the development of children and adolescents, and are committed to a more efficient economic approach to mental health services.
The newly revised and updated Hormones, Second Edition provides a comprehensive treatment of human hormones, viewed in light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. Each chapter presents a physiological description of the hormone system under consideration, followed by a listing of the mode-of-action of the hormone. This book includes significant advances in the molecular biology of receptors, hormones, and studies of hormone action that have transpired over the past five years. The text updates the material on enzymes related to steroid metabolism and new hormone systems, as well as providing a new chapter on hormones and cancer. - Completely updates the material, covering new discoveries and significant advances since the First Edition was published in 1987 - Contains new information regarding steroid hormones, the role of hormones in cancer, and a comprehensive introductory chapter - Presents an overview of virtually all important hormones - Provides detailed physiological, cellular, and molecular descriptions of classical human endocrine systems - Streamlines the presentation of the First Edition, making the book easier to use and read
Drawing heavily on the reminiscences of the Brownsville boys themselves, and skillfully integrating these with material from newspapers, books, and commentary of the time, Sorin creates an original and compelling picture of the communal and individual vitality that allowed an unusual and heartening social achievement.
This comprehensive volume identifies and analyzes the significant ideas and institutions that shaped the Western educational heritage. The author examines how worldwide events have impacted education in Europe, North America, and beyond. The third edition incorporates fresh material about the ancient world, European exploration and colonization of North America and India, as well as updated chapters on education in the United Kingdom, France, Germany, and Russia. This edition has an expanded treatment of Carl Jung, a new section on Margaret Naumburg and her Walden School, and enhanced analysis of many other theorists. It concludes with broadened coverage of nineteenth, twentieth, and twenty-first century American education, including many educators new to the third edition. Each chapter contains a new feature: Reflection, Discussion, and Research. From Plato and Aristotle to John Dewey, leading educators raised perennial concepts about education and truth, meaning, and value that remain relevant today. In the progression from antiquity to the present, some issues are marked by change and others by continuity—all of which are important to consider, discuss, and research further.
After thirty years, PPID is still the reference of choice for comprehensive, global guidance on diagnosing and treating the most challenging infectious diseases. Drs. Mandell, Bennett, and Dolin have substantially revised and meticulously updated, this new edition to save you time and to ensure you have the latest clinical and scientific knowledge at your fingertips. With new chapters, expanded and updated coverage, increased worldwide perspectives, and many new contributors, Mandell, Douglas, and Bennett’s Principles and Practice of Infectious Diseases, 7th Edition helps you identify and treat whatever infectious disease you see. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Get the answers to questions you have with more in-depth coverage of epidemiology, etiology, pathology, microbiology, immunology, and treatment of infectious agents than you’ll find in any other infectious disease resource. Find the latest diagnoses and treatments for currently recognized and newly emerging infectious diseases, such as those caused by avian and swine influenza viruses. Put the latest knowledge to work in your practice with new or completely revised chapters on influenza (new pandemic strains); new Middle East respiratory syndrome (MERS) virus; probiotics; antibiotics for resistant bacteria; antifungal drugs; new antivirals for hepatitis B and C; Clostridium difficile treatment; sepsis; advances in HIV prevention and treatment; viral gastroenteritis; Lyme disease; Helicobacter pylori; malaria; infections in immunocompromised hosts; immunization (new vaccines and new recommendations); and microbiome. Benefit from fresh perspectives and global insights from an expanded team of international contributors. Find and grasp the information you need easily and rapidly with newly added chapter summaries. These bulleted templates include diagnosis, therapy, and prevention and are designed as a quick summary of the chapter and to enhance relevancy in search and retrieval on Expert Consult. Stay current on Expert Consult with a thorough and regularly scheduled update program that ensures access to new developments in the field, advances in therapy, and timely information. Access the information you need easily and rapidly with new succinct chapter summaries that include diagnosis, therapy, and prevention. Experience clinical scenarios with vivid clarity through a richly illustrated, full-color format that includes 1500 photographs for enhanced visual guidance.
This detailed and comprehensive guide provides biographical information on the most influential and significant figures in world anthropology, from the birth of the discipline in the nineteenth century to the present day. Each of the fifteen chapters focuses on a national tradition or school of thought, outlining its central features and placing the anthropologists within their intellectual contexts. Fully indexed and cross-referenced, The Routledge Dictionary of Anthropologists will prove indispensable for students of anthropology.
This is an updated version of the very successful first edition which condenses and synthesizes a variety of drawing directives that aid clinicians in the assessment process, as well as in therapy.
Clinicians are always in need of enticing techniques to engage clients on a daily basis, especially those who are nonverbal or initially opposed to feedback. Using Drawings in Clinical Practice provides a rich variety of drawing directives to enhance the diagnostic process. In this highly illustrated text, clinicians will discover the tools they need to interact effectively with their clients. The book places special emphasis on intake interviewing and psychological testing, where the potential for uncovering hidden conflicts and therapeutic direction is especially poignant. Case studies provide a comprehensive overview of how to introduce simple drawings and gain remarkable insights. Using Drawings in Clinical Practice is a crucial guidebook for professionals who seek new ways to facilitate meaningful communication and interactions in their practice settings.
With more international contributors than ever before, Block’s Disinfection, Sterilization, and Preservation, 6th Edition, is the first new edition in nearly 20 years of the definitive technical manual for anyone involved in physical and chemical disinfection and sterilization methods. The book focuses on disease prevention—rather than eradication—and has been thoroughly updated with new information based on recent advances in the field and understanding of the risks, the technologies available, and the regulatory environments.
Traces the history of Dutch-Americans discussing why each wave of immigrants left Holland, where they settled, and their way of life in and contributions to their new country from colonial times to the present.
Featuring 127 new drug entries, the eighth edition of this popular reference provides practical, reliable information on more than 1,175 drugs that may be used by pregnant and lactating women.
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