Upshur County, West Virginia was created in 1851 from Randolph, Barbour, and Lewis counties. Upshur's early history and the lives of its more prominent pioneers and nineteenth-century Native Sons are ably captured in this tripartite volume. Part I, a condensed history of the state prepared by Hu Maxwell, ranges over everything from the first explorations of the Blue Ridge, the French and Indian War, and the Revolution to West Virginia geography and geology, formation of the state, and the Civil War in West Virginia. In Part II, Mr. Cutright lays out the history of the county, with emphasis on the Indian Wars, religious life, geography, formation of the county and its political and governmental institutions, Upshur County and Upshur countians in the Civil War, as well as a whole host of miscellaneous topics, such as turnpike and railroad construction, newspapers, financial institutions, the birds of Upshur County, and much more. In the final third of the volume we find an alphabetically arranged series of over 600 biographical/genealogical sketches of Upshur countians (some of them illustrated), which range from several paragraphs to several pages in length. In the majority of cases the subjects, who were mostly born around mid-century, are identified by their year of birth, the name of one or more parents, and the names of their spouse(s) and children. In addition, we learn something of each subject's career, military service (if any), and his/her movements to and from Upshur County. In short, given the book's 607 densely packed pages of historical and genealogical detail, this is the starting point for Upshur County research.
Having received the invitation from Springer-Verlag to produce a volume on drug-induced birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world's literature. We chose a three-pronged approach, centered around those particular drugs for which we have a relatively well established basis for understanding how they exert their unwanted effects on the human embryo. We then supplemented this information with a series of reviews of critical biological processes involved in the established normal developmental patterns, with emphasis on what happens to the embryo when the processes are perturbed by experimental means. Knowing that the search for mechanisms in teratology has often been inhibited by the lack of understanding of how normal development proceeds, we also included chapters describing the amazing new discoveries related to the molecular control of normal morphogenesis for several organ systems in the hope that the experimental toxicologists and molecular biologists will begin to better appreciate each others questions and progress. Several times during the last two years of developing outlines, issuing invitations, reviewing chapters, and cajoling belated contributors, we have wondered whether we made the correct decision to undertake this effort.
Includes a description of the Alpha-, Beta-, Delta-, and Epsilonproteabacteria (1256 pages, 512 figures, and 371 tables). This large taxa include many well known medically and environmentally important groups. Especially notable are Acetobacter, Agrobacterium, Aquospirillum, Brucella, Burkholderia, Caulobacter, Desulfovibrio, Gluconobacter, Hyphomicrobium, Leptothrix, Myxococcus, Neisseria, Paracoccus, Propionibacter, Rhizobium, Rickettsia, Sphingomonas, Thiobacillus, Xanthobacter and 268 additional genera.
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