Examination of the debate surrounding Attention Deficit Hyperactivity Disorder. Investigates the theory that many health workers fail to make a 'holistic' assessment of a child within a family and social context, leading many children with problematic behaviours to be misdiagnosed as having ADHD. Also analyses other contributing factors such as social and economic changes, parental depression and classroom management issues. Includes contributor notes and references. Published in both paperback and PDF formats.
Paxinos and Ashwell's Atlas of the Developing Rat Nervous System, Fourth Edition, builds on the many excellent features of previous editions that have made this book the most cited atlas of the developing rat brain. It provides the most comprehensive depiction of not only the structures in the brain and spinal cord, but also of the peripheral nervous system and target organs that are important for developmental neurobiologists, allowing the user to follow neural structures through the developing embryo in both time and space. The nomenclature and identification of structures in this edition have been thoroughly updated to ensure accuracy and compatibility. - Provides detailed and accurate coverage of the developing rat nervous system from Embryonic Day 11 to Day of Birth - Contains 200 photographs and accompanying diagrams of coronal or sagittal sections of rats aged E11 – E19 - Presents new sections on Histology, Neurogenetics, Imaging, MRI Histology and Panneuronal Markers - Delineates brain structures and peripheral nerves, ganglia, arteries, veins, muscles, bones and other important organs - Serves as an essential tool for researchers in the interpretation of findings resulting from the genetic manipulation of brain development - Includes the Expert Consult eBook version, compatible with PC, Mac, and most mobile devices and eReaders, which allows readers to browse, search, and interact with content
This atlas provides an accurate and detailed depiction of all brain structures at fetal stage E17.5, Day of birth, and Day 6 postnatal. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs. It is an indispensable guide for the interpretation of nervous system changes in gene knockout and transgenic mice. Contains: 43 photographs and drawings of Nissl-stained coronal sections of the brain of a fetal mouse at E17.5 days, 65 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse on the day of birth, and 73 photographs and drawings of Nissl-stained coronal sections of the brain of a mouse aged 6 days postnatal. The drawings are based on the study of sections stained with Nissl and a range of neuroactive substances. In addition to brain structures, the atlas delineates peripheral nerves, ganglia, arteries, veins, muscles bones and other organs.
Suitable for advanced undergraduates and graduate students in engineering, this text introduces the concepts of plasma physics and magnetohydrodynamics from a physical viewpoint. The first section of the three-part treatment deals mainly with the properties of ionized gases in magnetic and electric fields, essentially following the microscopic viewpoint. An introduction surveys the concepts of ionized gases and plasmas, together with a variety of magnetohydrodynamic regimes. A review of electromagnetic field theory follows, including motion of an individual charged particle and derivations of drift motions and adiabatic invariants. Additional topics include kinetic theory, derivation of electrical conductivity, development of statistical mechanics, radiation from plasma, and plasma wave motion. Part II addresses the macroscopic motion of electrically conducting compressible fluids: magnetohydrodynamic approximations; description of macroscopic fluid motions; magnetohydrodynamic channel flow; methods of estimating channel-flow behavior; and treatment of magnetohydrodynamic boundary layers. Part III draws upon the material developed in previous sections to explore applications of magnetohydrodynamics. The text concludes with a series of problems that reinforce the teachings of all three parts.
Functioning as a toolkit for inclusive urban planning, this book acts as both a model for understanding the planning and management of this framework, and a foundation for future research.
Born raconteur George Lang tells the Horatio Alger story--as only he can tell it--of his extraordinary life. Born in Hungary, only child of a Jewish tailor and destined for the concert stage, at nineteen he was incarcerated in a forced-labor camp, never to see his parents again. After he landed in New York in 1946, a whole new world opened up as he switched from the violin to the kitchen. Soon he was orchestrating banquets at the Waldorf for Khrushchev, Queen Elizabeth, Princess Grace, and the like. He invented a new profession: as the first restaurant consultant, he explored Indonesia and the Philippines to bring back exotic tastes for the 1964 World's Fair, and pioneered upscale restaurant complexes within shopping malls. Finally he resurrected two great landmarks: the Café des Artistes in New York and Gundel in his native Hungary.
Ions, their transport across membranes, and their flow through specialized ion channels are central to the understanding of brain function, normal and pathological. The first part of this book deals with the regulation of ions in brain extra- and intracellular fluids. Regulation is effected by the blood-brain barrier, and by membrane ion pumps and other transport mechanisms of neurons and glial cells. Normally adjusted for optimal neural function, ion levels can change and alter the excitability of neurons and influence synaptic transmission in healthy and diseased brains. After an introduction to the electrophysiology of epilepsy, and a description of experimental seizure "models," the second part discusses the roles of the faulty regulation of ions and of the diseases of ion channels in generating epileptic seizures. The mechanisms of action of various anticonvulsant drugs are also considered. The third part is devoted to the phenomenon of spreading depression and its likely role in human diseases. The final chapters of the book deal with the role of ions in the devastation caused by lack of oxygen and by insufficient blood flow to brain tissue, and the reasons for the exceptional vulnerability of certain classes of central neurons in hypoxia and stroke. The book will be of interest to neuroscientists, neurobiologists, neurophysiologists, neurologists, neurosurgeons, and to their students and trainees.
Today's ubiquitous computing technology is imbedded in everyday objects from cars to clothes to shipping containers, whose location, context, and state can be monitored, instantly processed, and acted upon. This new volume in the "Advances in Management Information Systems" series provides an in-depth review of the state-of-the-art practices and research opportunities in a new era where information technology resides in physical space. Written for both scholars and practitioners, "Pervasive Information Systems" is organized into three sections, each investigating a distinct part of the subject. Part I focuses on the design challenges of Pervasive Information Systems (PS), and discusses issues relating to the coordination of PS through middleware structures as well as issues related to the efficient deployment of PS. Part II discusses the challenges and limitations of deploying pervasive technologies to support domestic, corporate, and public systems. Part III presents two emerging research fields of PS - design for aesthetics and PS evaluation.
George Jean Nathan (1882-1958) was formative influence on American letters in the first half of this century, and is generally considered the leading drama critic of his era. With H. L. Mencken, Nathan edited The Smart Set and founded and edited The American Mercury, journals that shaped opinion in the 1920s and 1930s. This series of reprints, individually introduced by the distinguished critic and novelist Charles Angoff, collects Nathan's penetrating, witty, and sometimes cynical drama criticism.
Why melancholia is a vital form of social critique and a catalyst for political renewal Melancholia is wrongly condemned as a condition of withdrawal and despair that alienates its sufferer from community. Countering that misconception, A Politics of Melancholia reclaims an understanding of melancholia not as an affliction in need of a remedy but as an affirmative stance toward decay and ruination in political life, and restores the melancholic figure—by turns inventive and destructive, outraged and inspired—to their rightful place as the poet of political thought. George Edmondson and Klaus Mladek identify pivotal moments of political melancholia in ancient and modern texts, offering new perspectives on the death of Socrates in Plato’s dialogues, the fratricide in Hamlet, Woyzeck’s killing of Marie in Georg Büchner’s Woyzeck, the murder of Moses in Freud’s thought, and the betrayal of the revolutionary idea that Hannah Arendt identifies in her critique of eighteenth-century revolutions. Melancholia emerges here as a disposition that is mournful but also jubilant, a mood of unbending disconsolation that remains faithful to a scene of downfall, to events that cannot be forgotten, and to things that cannot be governed. Recovering a tradition of thought that is both affirmative and hopeful, this eloquent book reveals how political melancholia embodies a shared condition of discontent that binds communities together and inspires change.
Stay on top of the rapid changes sweeping endocrinology today with the latest information on important selected topics in The Handbook of Endocrinology. This extensive two-volume text provides an impressive breadth and depth of coverage difficult to find in other sources. After a broad survey of the functions of major endocrine glands, the book launches into detailed reviews of both established and hot, new research areas. Selected topics include:
Synthetic Peptides discusses racemization, protecting group techniques, peptide bond-forming methodology, amino acids, and dipeptide syntheses. The book explains solid phase synthesis methods, cyclopeptides, nucleopeptides, chromopeptides of the actinomycin D type, and cites examples of syntheses of peptides of different sizes. The text describes tripeptides, tetrapeptides, pentapeptides, hexapeptides, and also undecapeptides to nonadecapeptides. Riniker and colleagues explain the revised structures (for the human and porcine hormone, Asn for Asp at position 25 and Glu for Gin at position 30) for the 39-unit adrenocorticotropic hormone. A synthesis of the 32-unit human calcitonin M is associated with the fragment condensation approach to complex peptides. The book also reviews cyclodepsipeptide valinomycin based on the possible transport of a potassium ion through biological membranes by this substance and the synthesis of a D-Pro analog. The text describes the cyclic decapeptide antibiotic gramicidin S, belonging to a family of similar substances isolated from Bacillus brevi, that can treat certain eye-threatening infections. The book can prove beneficial for biochemists, micro-biologists, cellular investigators, and researchers involved in physiology, oncology or therapeutics.
Dr. George E. Onet and his wife Virginia, both veterinarians working in Romanian academia, managed to escape from an oppressive regime back in 1985, asked for political asylum in the United States and they lived in this country ever since. In a succession of extraordinary events, the author describes how he and his wife, after having been repeatedly denied tourist visas to visit Greece, decided to defect to West Europe, leaving behind their beloved family members, their belongings, their reputable social positions. In pursuit of freedom and happiness, they were confronted with a lot of difficulties, unpredictable events, and went through many emotionally critical moments.
A comprehensive source of traditional architectural details for anyone working with old structures Compiling the most useful material from the first four editions of Architectural Graphic Standards published between 1932 and 1951, this book brings back into circulation hundreds of architectural illustrations and standards that have once again become relevant to design work. Chapters cover all facets of building construction from foundations to furnishings and are structured to follow the drawing preparation sequence of a typical rehabilitation project. Architects, designers, and others involved in rebuilding and renovating structures built in decades past will find here many of the details and information used by the original architects and builders. Impeccably organized and beautifully rendered, this handsome reference is both a terrific working tool and a wonderful addition to an architecture library.
A leading expert on East and Central European and Soviet affairs, George R. Urban offers an insider's perspective on the history of Radio Free Europe by drawing on his service during the 1960s and his term as overall director in the 1980s. In vivid detail, Urban describes how the Radios promoted the cause of liberal democracy and the free market economy for more than four decades and stood up against the Soviet system, with its clandestine offshoots and fifth columns in all the countries of the West. Urban contends that a second opponent was less visible but more powerful: influential members of the American and West European Left who believed that the Soviet superpower should not be thwarted. The author explores the often controversial strategies and tactics employed by the staff and administrators of the Radios, sheds light on their role in the tragic 1956 Hungarian Revolution, examines the ideas and convictions of key figures, and reveals how communism was intellectually unmasked in a psychological contest that also made possible reconciliation between nations and individuals.
The preceding editions made The Rat Brain in Stereotaxic Coordinates the second most cited book in science. This Fifth Edition is the result of years of research providing the user with the drawings of the completely new set of coronal sections, now from one rat, and with significantly improved resolution by adding a third additional section level as compared to earlier editions. Numerous new nuclei and structures also have been identified. The drawings are presented in two color, providing a much better contrast for use. The Fifth Edition continues the legacy of this major neuroscience publication and is a guide for all students and scientists who study the rat brain. - 161 coronal diagrams based on a single brain. - Delineations drawn entirely new from a new set of sections. - Diagrams spaced at constant 120 μm intervals resulting in the high resolution and convenience of use. - Drawings use blue color lines and black labels to facilitate extraction of information. - The stereotaxic grid was derived using the same techniques that produced the widely praised stereotaxic grid of the previous editions. - Over 1000 structures identified, a number for the first time in this edition.
Having received the invitation from Springer-Verlag to produce a volume on drug-induced birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world's literature. We chose a three-pronged approach, centered around those particular drugs for which we have a relatively well established basis for understanding how they exert their unwanted effects on the human embryo. We then supplemented this information with a series of reviews of critical biological processes involved in the established normal developmental patterns, with emphasis on what happens to the embryo when the processes are perturbed by experimental means. Knowing that the search for mechanisms in teratology has often been inhibited by the lack of understanding of how normal development proceeds, we also included chapters describing the amazing new discoveries related to the molecular control of normal morphogenesis for several organ systems in the hope that experimental toxicologists and molecular biologists will begin to better appreciate each others questions and progress. Several times during the last two years of developing outlines, issuing invitations, reviewing chapters, and cajoling belated contributors, we have wondered whether we made the correct decision to undertake this effort.
In this provacative study of the "disease" afflicting American industry today, George Lodge, a distinguished professor at the Harvard Business School, reveals the malady as a psychological disorder, characterized by a refusal to face the facts of interdependence in a competetive world; by a reluctance to confront the grave inadequacies in the operation of our great institutions—business, labor, and government; and by the fact that "leaders do not lead; those with responsibility do not fight. Timidity, born of resignation, discourages change." Lodge begins by defining the disease through its symptoms: failing industries, stubborn unemployment, lagging economic growth, stagnant productivity, overseas competition, focus on short-term financial gain, and, perhaps most telling, the pervasive feeling among Americans that their land of plenty has become a land of want. He examines the gradually changing roles and relationships between government, great corpoations, and trade unions that are nevertheless obscure by traditional and detrimental assumptions, distrust, and a set of ideologies that are increasingly inefficient, ineffective, inconsistent, and irrelevant. And he finds the incoherence of American industrial policy exemplified by the fact the we preach the old virtues of free trade and the sanctity of the market while in actuality we pursue a strategy—including tax incentives and trade subsidies—the misshapes the free market. Based on interviews with more than 150 leaders of the nation's institutions, The American Disease goes beyond diagnosis to offer logical and feasible proposals to cure this dangerous condition. Lodge suggests, for example, that the office of the United States Trade Representative be expanded and strengthened to deal with the growing pressure for protection against imports and with the confusion among our trading partners. He shows why business and labor must work together more closely in a non-adversarial way with federal and local government to determine community needs. He explains why Washington will be forced to direct the future of electric power in America, rather than leave the decisions to fifty different sets of state regulators. And he makes a number of recommendations to alter the ways in which corporations manage themselves and deal with government, and to reduce the social and economic costs that are implicit in these changes. George C. Lodge believes that recovery from our institutional ailments is possible, and this timely and perceptive book offers a resoundingly rational course toward that crucial goal.
This long-awaited update of the classic, The Human Nervous System, stands as an impressive survey of our knowledge of the brain, spinal cord, and peripheral nervous system. The book has been completely redone and brought up-to-date. An impressive and respected cast of international authors have contributed 37 chapters on topics ranging from Brain Evolution, all phases of Brain Development, to all areas of the adult brain and peripheral pathways, along with careful descriptions of the spinal cord and peripheral nervous system, brainstem and cerebellum. The Human Nervous System, Second Edition will again serve as the gold standard, providing a one-stop source of up-to-date information about our knowledge of the human nervous system.This second edition of the standard reference on the human nervous system is extensively and completely revised and updated from the 1990 first edition. Written by the leading researchers, many chapters have been completely rewritten, new chapters have been added. A new section on Evolution and Development provides a broader perspective, and all chapters include references and perspectives to neurological disease.
Encyclopedia of Plague and Pestilence, Third Edition is a comprehensive A-to-Z reference offering international coverage of this timely and fascinating subject. This updated volume provides concise descriptions of more than 700.
The Mammalian Spinal Cord provides a comprehensive account of the anatomy and histology of the spinal cord. The text covers the cytoarchitecture, chemoarchitecture, motor neuron distribution, long tracts, autonomic outflow, and gene expression in the spinal cord. A feature of the book is the inclusion of segment-by-segment atlases of the spinal cords of rat, mouse, newborn mouse, marmoset, rhesus monkey, and human. This book is an essential reference for researchers studying the spinal cord. - Includes full-color photographic images of Nissl-stained sections from every spinal cord segment in each of two rodent and three primate species, over 160 Nissl plates - Contains comprehensively labeled diagrams to accompany each Nissl-stained section, over 160 diagrams - Provides more than 500 photographic images of sections stained for AChE, ChAT, parvalbumin, NADPH- diaphorase, calretinin, or other markers to supplement the Nissl-stained images
Work on the human brainstem has been impeded by the unavailability of a comprehensive diagrammatic and photographic atlas. In the authors' preliminary work on the morphology of the human brainstem (The Human Nervous System, 1990), Paxinos et al demonstrated that it is possible to use chemoarchitecture to establish a number of human homologs in structures known to exist in the rat, the most extensively studied species. Now, with the first detailed atlas on the human brainstem in more than forty years, the authors present an accurate, comprehensive, and convenient reference for students, researchers, and pathologists. Key Features * The first detailed atlas on the human brainstem in more than forty years * Delineated as accurately as The Rat Brain in Stereotaxic Coordinates, Second Edition (Paxinos/Watson, 1986), the most cited book in neuroscience * Based on a single brain from a 59-year-old male with no medical history of neurological or psychiatric illness * Represents all areas of the medulla, pons, and midbrain in the plane transverse to the longitudinal axis of the brainstem * Consists of 64 plates and 64 accompanying diagrams with an interplate distance of half a millimeter * The photographs are of Nissl and acetylcholinesterase (AChE) stained sections at alternate levels * Establishes systematically the human homologs to nuclei identified in the brainstem of the rat Reviewed by leading neuroanatomists * An accurate and convenient guide for students, researchers, and pathologists
This completely revised edition of The Rat Brain in Stereotaxic Coordinates, the second most cited book in science, represents a dramatic update from the previous edition. Based on a single rat brain, this edition features an entirely new coronal set of tissue cut in regular 120 micron intervals with accompanying photographs and drawings of coronal, horizontal and sagittal sections of this new set. The use of the single brain allows for greater consistency between sections, while advances in histochemistry techniques provides increased refinement in the definition of brain areas, making this the most accurate and detailed stereotaxic rat atlas produced to date. The atlas will also include a CD-ROM featuring all of the graphics and text. Every lab working with the rat as an experimental animal model will want to use this book as their atlas of choice.This book is also available in a softcover spiral binding at the same price. - Includes twice as many coronal sections, nissl plates, and sagittal plates as the previous edition - Uses a single rat brain allowing for better consistency and better delineations in the line drawings of structures - Provides improved stereotaxic coordinates at a higher level of detail - Accompanying CD-ROM features graphics and text - Now available as hardcover version and softcover version with a spiral binding at the same price
Addressing important extensions of the relational database model, including deductive, temporal, and object-oriented databases, this book provides an overview of database modeling with the Entity-Relationship (ER) model and the relational model. The book focuses on the primary achievements in relational database theory, including query languages, integrity constraints, database design, computable queries, and concurrency control. This reference will shed light on the ideas underlying relational database systems and the problems that confront database designers and researchers.
A completely revised and updated edition of the leading mammalogy textbook, featuring color photographs throughout and a new streamlined structure for enhanced use in courses. There are more than 6,400 species in the class Mammalia, including the blue whale—the largest animal that has ever lived—and the pygmy shrew, which weighs little more than a dime. Such diversity among mammals has allowed them to play critical roles in every ecosystem, whether marine, freshwater, alpine, tundra, forest, or desert. Reflecting the expertise and perspective of five leading mammalogists, the fifth edition of Mammalogy: Adaptation, Diversity, Ecology significantly updates taxonomy, adds a new introductory chapter on the science of mammalogy, and highlights several recently described species. To enhance its appeal to students, textual material has been reduced, consolidated, and streamlined without sacrificing breadth or depth of coverage. The fifth edition includes • for the first time, stunning color photographs throughout • chapters rearranged and grouped to best reflect phylogenetic relationships, with updated numbers of genera and species for each family • updated mammalian structural and functional adaptations, as well as ordinal fossil histories • recent advances in mammalian phylogeny, biogeography, social behavior, and ecology, with 12 new or revised cladograms reflecting current research findings • new breakout boxes on novel or unique aspects of mammals • new work on female post-copulatory mate choice, cooperative behaviors, group defense, and the role of the vomeronasal system • discussions of the current implications of climate change and other anthropogenic factors for mammals Maintaining the accessible, readable style for which Feldhamer and his coauthors are well known, this new edition of Mammalogy is the authoritative textbook on this amazingly diverse class of vertebrates.
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