The Mammalian Spinal Cord provides a comprehensive account of the anatomy and histology of the spinal cord. The text covers the cytoarchitecture, chemoarchitecture, motor neuron distribution, long tracts, autonomic outflow, and gene expression in the spinal cord. A feature of the book is the inclusion of segment-by-segment atlases of the spinal cords of rat, mouse, newborn mouse, marmoset, rhesus monkey, and human. This book is an essential reference for researchers studying the spinal cord. - Includes full-color photographic images of Nissl-stained sections from every spinal cord segment in each of two rodent and three primate species, over 160 Nissl plates - Contains comprehensively labeled diagrams to accompany each Nissl-stained section, over 160 diagrams - Provides more than 500 photographic images of sections stained for AChE, ChAT, parvalbumin, NADPH- diaphorase, calretinin, or other markers to supplement the Nissl-stained images
The authors of the most cited neuroscience publication, The Rat Brain in Stereotaxic Coordinates, have written this introductory textbook for neuroscience students. The text is clear and concise, and offers an excellent introduction to the essential concepts of neuroscience. - Based on contemporary neuroscience research rather than old-style medical school neuroanatomy - Thorough treatment of motor and sensory systems - A detailed chapter on human cerebral cortex - The neuroscience of consciousness, memory, emotion, brain injury, and mental illness - A comprehensive chapter on brain development - A summary of the techniques of brain research - A detailed glossary of neuroscience terms - Illustrated with over 130 color photographs and diagrams This book will inspire and inform students of neuroscience. It is designed for beginning students in the health sciences, including psychology, nursing, biology, and medicine. - Clearly and concisely written for easy comprehension by beginning students - Based on contemporary neuroscience research rather than the concepts of old-style medical school neuroanatomy - Thorough treatment of motor and sensory systems - A detailed chapter on human cerebral cortex - Discussion of the neuroscience of conscience, memory, cognitive function, brain injury, and mental illness - A comprehensive chapter on brain development - A summary of the techniques of brain research - A detailed glossary of neuroscience terms - Illustrated with over 100 color photographs and diagrams
This book offers a conceptual explanation of the interrelationships that exist between the stages in the progression of initiated epithelial cells in culture compared with the diverse tissue of organs and the progression of tumors from different organ sites. The fate of the modification of adducts is discussed at the molecular level. The role that modifications in hot spots in oncogenes and supressor genes play at the molecular level and how these molecular modifications can lead to an explanation of molecular control in the formation of tumor phenotypes is also examined. Researchers in cell biology and toxicology, applied pharmacology, carcinogenesis, teratogenesis, mutagenesis, and molecular toxicology will find the book useful, interesting reading.
Two geographical perspectivesspatial and ecologicalgive students an understanding of patterns, processes, and the interrelationships of living and nonliving elements.
Publsihed in 1998, this book examines the relationship between responsibility and criminal liability through an analysis of provocation and related criminal defences. It begins by identifying fundamental questions about the role of justifications and excuses in the criminal law as they emerge from the discussion of philosophical theories of responsibility. Following an outline of the distinction between murder and manslaughter and its history, the basic doctrinal issues relating to the nature and rationale of provocation and other partial defences are then identified and discussed in depth, together with the circumstances under which these defences can be raised. Although the analysis focuses, for the most part, on English law, the references to other legal systems which are included in the work add an important comparative perspective to the discussion of the issues. The book should be of special interest to criminal lawyers, legal theorists and students interested in comparative criminal law and jurisprudence.
Aims to describe why and how applied research carried out in a national public health program sometimes influenced program action in the field - and sometimes did not. This title presents and analyses a number of modified case studies to draw some practical lessons and to provide a theoretical basis for future program action.
Recognized as the definitive starting point for twentieth-century ethical theory, the text is reprinted with the previously unpublished preface Moore wrote for a planned, but never completed, second edition. "Free Will" and "The Conception of Intrinsic Value" are also included from his later ethical writings.
On August 7, 1862, George Alfred Hitchcock (born in Massachusetts in 1844) was mustered into Company A, 21st Massachusetts Infantry. From this date until January 1, 1865, he kept a meticulous daily diary. His first experience in battle was at Fox's Gap on South Mountain, and then an attack across Burnside's Bridge at Antietam. Then came the disastrous Union advance toward Marye's Heights at Fredericksburg; a journey by rail to Paris, Kentucky, via Pittsburgh, Columbus (drunken 21st Infantry soldiers in conflict with local security) and Cincinnati; the protection of the Mount Sterling, Kentucky, area from guerrillas; an expedition from Camp Nelson through the Cumberland Gap to eastern Tennessee; Burnside's Knoxville campaign; the arduous winter return march to Camp Nelson with Confederate prisoners; efforts to regain his health and a return to the 21st Regiment; and a compelling account of his capture at Cold Harbor and imprisonment at Andersonville and Millen, Georgia, and Florence, South Carolina; and finally, his release.
Atlas of the Developing Mouse Brain, Second Edition builds on the features of successful first edition, providing a comprehensive and convenient reference for all areas of the mouse brain at Fetal-Day 17.5 (E17.5), Day-of-Birth (P0), and Day-Six postnatal (P6). The book also delineates the parts of the eye, features of the skull, ganglia, nerves, arteries, veins, bones and foramina. This atlas is an essential tool for researchers and students who study the development of the mouse brain, or for those who interpret findings from genetic manipulation. - Contains 176 high-resolution color scans of Nissl-stained coronal sections of the brain and skull of the fetal (E17.5), day-of-birth (P0), and day-six postnatal mouse (P6) - Includes diagrams that delineate all structures of the brain, as well as peripheral nerves, ganglia, muscles, bones, veins and arteries of the head - Presents approximately 5000 corrections and updates from the first edition - Includes color codes of the veins, arteries, nerves and ganglions of the skull in diagrams
Paxinos and Franklin's The Mouse Brain in Stereotaxic Coordinates, Compact Fifth Edition, is the compact version of the most widely used and cited atlas of the mouse brain in print. It emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience. The compact edition provides the coronal plates and diagrams of the full mouse atlas in a smaller, more convenient spiral format and at a student friendly price. High resolution digital photographs of the coronal plane of section from the full 5th edition complement the coronal drawings. Unique to the compact, it includes an introduction to the use of the atlas in stereotaxic surgery. Contains 100 coronal diagrams that were fully revised for this new edition Includes 100 coronal photographic plates produced from directly scanned, very high-resolution images of the biological sections (done at the Allen Institute) Provides a beginner's guide with 25 pages on conducting stereotaxic surgery and how to use the atlas Presents surface views of the brain with labels over the major structures Uses the best ontology tree (nomenclature based on the development of the brain) with universal applications across mammals
Clinical Nuclear Cardiology—now in its fourth edition—covers the tremendous clinical growth in this field, focusing on new instrumentation and techniques. Drs. Barry L. Zaret and George A Beller address the latest developments in technology, radiopharmaceuticals, molecular imaging, and perfusion imaging. Thoroughly revised to include 20 new chapters—Digital/Fast SPECT, Imaging in Revascularized Patients, and more—this new edition provides state-of-the-art guidance on key areas and hot topics with stunning visuals. Online access to the fully searchable text at expertconsult.com includes highly illustrated case studies that let you see the problem using a variety of imaging modalities. In other words, this is an invaluable resource no clinician or researcher in nuclear cardiology should be without. - Features an editorial and contributing team of worldwide leaders in nuclear cardiology to provide you with current and authoritative guidance. - Includes a section focusing on acute coronary syndromes to provide you with practical management tools for these conditions. - Presents a full-color design that allows color images to be integrated throughout the text. - Includes access to the fully searchable contents of the book online at expertconsult.com, along with highly illustrated case studies that let you see the problem using a variety of imaging modalities. - Features 20 new chapters including Cellular Mechanisms of Tracer Uptake and Clearance; Attenuation/Scatter Corrections: Clinical Aspects; Hybrid Imaging; Digital/Fast SPECT; Imaging in Revascularized Patients; and more. - Focuses on perfusion imaging in a section dedicated to this hot topic so you get all the information you need to stay current.
The Rat Brain in Stereotaxic Coordinates provides an atlas of the rat brain. The main features of this atlas are: (1) It is based on the flat-skull position, and bregma, lambda, or the midpoint of the interaural line can be used as a reference point. (2) The atlas is based on the study of 130 adult male Wistar rats (with a weight range of 270-310 g). It is suitable for brains of 250-350 g male rats. (3) It represents all areas of the brain and spinal cord, and brain areas are shown in coronal, sagittal, and horizontal planes. The brain sections shown were taken at 0.5 mm intervals and were stained with either cresyl violet or for the demonstration of acetylcholinesterase (AChE). (4) It is based on fresh brains frozen in the skull (using deeply anaesthetized rats) in order to overcome distortion produced by fixation and to enhance staining contrast. (5) Structures are delineated on the basis of data on cytoarchitecture, connectivity, histochemistry, and development. The book is intended for researchers and graduate students in the neurosciences. Senior undergraduates should also find the atlas a useful adjunct to readings and lectures in brain anatomy and function.
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