Many of us in science have this "Aha!" moment when the mental puzzle is put together and you get a clear picture of a product, which will change the world. Moreover, you have a clear understanding of how it can be a commercial success. So, you decide to start a new company, a startup, and have a clear path to success. However, soon you come face to face with reality, where things are much more complicated. Only a minute fraction of startups survives and becomes successful. This is particularly true in the complex world of medical devices. There are many good books on startups but this book is specifically about startups specializing in medical devices, which are very different from other ones. It is written by a MedDev entrepreneur for first-time MedTech entrepreneurs.
An attractive book on the intersection of analysis and numerical analysis, deriving classical boundary integral equations arising from the potential theory and acoustics. This self-contained monograph can be used as a textbook by graduate/postgraduate students. It also contains a lot of carefully chosen exercises.
An extract from the review by the president of the International Association of Theory of Inventive Problem Solving, Mark Barkan: I have read Gennadiy Ivanovichs book Denis the Inventor and felt pity that I had not read it when I was 10-12 years old, but its never too late.
The book provides a detailed exposition of the calculus of variations on fibre bundles and graded manifolds. It presents applications in such area's as non-relativistic mechanics, gauge theory, gravitation theory and topological field theory with emphasis on energy and energy-momentum conservation laws. Within this general context the first and second Noether theorems are treated in the very general setting of reducible degenerate graded Lagrangian theory.
In the last decade, the development of new ideas in quantum theory, including geometric and deformation quantization, the non-Abelian Berry's geometric factor, super- and BRST symmetries, non-commutativity, has called into play the geometric techniques based on the deep interplay between algebra, differential geometry and topology. The book aims at being a guide to advanced differential geometric and topological methods in quantum mechanics. Their main peculiarity lies in the fact that geometry in quantum theory speaks mainly the algebraic language of rings, modules, sheaves and categories. Geometry is by no means the primary scope of the book, but it underlies many ideas in modern quantum physics and provides the most advanced schemes of quantization.
An extract from the review by the president of the International Association of Theory of Inventive Problem Solving, Mark Barkan: I have read Gennadiy Ivanovichs book Denis the Inventor and felt pity that I had not read it when I was 10-12 years old, but its never too late.
A Variation by Any Other Name... One of the most popular – and intriguing – variations of the Sicilian Defense is the so-called Chelyabinsk Variation. In the West, it is known as the Sveshnikov Variation, while older opening monographs may refer to it as the Lasker-Pelikan Variation. It is called the Chelyabinsk Variation in Russia. It is the variation that arises after 1.e4 c5 2.Nf3 Nc6 3.d4 cxd4 4.Nxd4 Nf6 5.Nc3 e5. Once dismissed by theoreticians as “anti-positional,” it is now common at all levels. In this monumental work, grandmaster Gennadi Timoshchenko, one of the creative founders of the entire line, puts the entire variation into both a personal and historical perspective and then examines the theory and practice of this line in great detail. From the foreword by Garry Kasparov: “Timoshchenko’s book on the Chelyabinsk Variation is both very interesting and necessary. Behind it lies an enormous amount of work, as will become evident as you read and especially play through the author’s analysis. Readers will be able to get a definitive insight into the genesis of the Chelyabinsk Variation...In its 200 chapters, more or less every important branch of the Chelyabinsk Variation is examined. It is also unusual as it contains a huge amount of novelties at various levels of importance.” Extraordinary analytical depth, cross-checked by strong engines, is complemented by historical and biographical perspectives to make this a truly unique opening manual. Regardless of what name you give it, Sicilian Defense: The Chelyabinsk Variation will provide you with a powerful weapon against 1.e4.
For many of whom I often told you, and even now am writing with tears, walk as the enemies of the cross of Christ: they walk to their final destruction, their god is the belly and their glory is in shameful things, their minds are earthly bound. But our πολίτευμα is in heaven from where we expect the Lord Jesus Christ, who is our Savior. Philippians 3:18-20 Paul’s letters to Philippians show us that this rather outspoken man had plenty of opportunity and cause to aggravate his christian contemporaries. However, for Paul to use such hostility and to name people as “enemies” shows us that we should take note and try to understand the meaning behind his statement. In this work the author asks: who were these enemies? What did they do wrong? Why did they deserve destruction? In search of these questions the investigation looks to the early Christian communities and their formation within the socio-political realities of the urban centers of the Roman Empire. Through this we learn a great deal about the uneven and complex dynamics of the early Christian community and a deep understanding of Paul’s warning to them.
This concise monograph is intended for students and scientists specializing in contemporary field theory, gravitation theory and modern differential geometry. The gauge theory as presented by the authors, incorporates Einstein's gravity into the universal picture of fundamental interactions and clarifies its physical nature as a Higgs field. A key point advanced here is the spontaneous breakdown of space-time symmetries according to the equivalence principle. The jet manifold generalization of the fibre bundle machinery is used to describe this symmetry breaking, degenerate Hamiltonian systems and general connections.
This handbook encapsulates 25 years of research in the Soviet Union into isomerization reactions, which display the relationship between the structure and the properties of compounds. The equilibria of isomers and, in part, calorimetric data are included.
This book discusses optical technologies for Diabetic Foot management. It combines the current medical literature review with an overview of the technology and physics behind it. Thus, it is a single-source introduction to the topic. It can also be used as a reference source and practical guide for the use of technology. The particular focus is on low-cost technologies, including hyperspectral imaging, thermography, and endogenous bacterial fluorescence. Moving diagnostic modalities closer to the patient (e.g., primary care) allows the disease to be detected at an earlier stage, thus improving outcomes. However, while some optical technologies are available commercially, they have not received wide clinical adoption due to gaps in knowledge translation to mainstream medicine. This book aims to narrow this gap with practical illustrations. The book will be of interest to a broad range of healthcare professionals, clinical researchers, engineers, and decision-makers, who are dealing with complications of diabetes. Key Features: Reviews the current state of technologies. Provides a practical guide with practical considerations and illustrations. Supplies a 360-degree view of the combination of clinical information with a technology background and primers on physics and engineering.
Localized Dynamics of Thin-Walled Shells focuses on localized vibrations and waves in thin-walled structures with variable geometrical and physical characteristics. It emphasizes novel asymptotic methods for solving boundary-value problems for dynamic equations in the shell theory, in the form of functions which are highly localized near both fixed and moving lines/points on the shell surface. Features First-of-its-kind work, synthesizing knowledge of the localization of vibrations and waves in thin-walled shells with a mathematical tool to study them Suitable for researchers working on the dynamics of thin shells and also as supplementary reading for undergraduates studying asymptotic methods Offers detailed analysis of wave processes in shells with varying geometric and physical parameters
This book incorporates 3 modern aspects of mathematical physics: the jet methods in differential geometry, Lagrangian formalism on jet manifolds and the multimomentum approach to Hamiltonian formalism. Several contemporary field models are investigated in detail.This is not a book on differential geometry. However, modern concepts of differential geometry such as jet manifolds and connections are used throughout the book. Quadratic Lagrangians and Hamiltonians are studied at the general level including a treatment of Hamiltonian formalism on composite fiber manifolds. The book presents new geometric methods and results in field theory.
This book presents a theoretical approach that allows the analysis of structures with magnetorheological and electrorheological layers, and shows, with the help of examples, how the mechanical behaviour of thin-walled laminated structures can be influenced. It consists of six chapters: Chapter 1 presents a brief overview of derivation approaches for theories of thin-walled structures, modelling of composites and modelling of laminated and sandwich structures. Chapter 2 describes the equivalent single layer model for thin laminated cylindrical shells, including the special cases of plates and beams. In addition to the classical mechanical properties, it also considers the electrorheological and magnetorheological properties. Chapter 3 presents the elastic buckling of laminated beams, plates, and cylindrical shells, discussing various problems, such as the influence of the boundary conditions, external loading and magnetic fields. It also suggests different approximations for asymptotic methods. Chapter 4 focuses on the free vibrations of elastic laminated beams, plates and cylindrical shells, investigating the influence of the boundary conditions and other factors. Chapter 5 presents the latest results concerning vibration of laminated structures composed of smart materials and discusses in detail the influence of electric and magnetic fields on smart structures. These results provide insights into the optimal design of these structures. Lastly, Chapter 6 features a short appendix presenting asymptotic estimates and series.
Radiation Processes In Crystal Solid Solutions is a monograph explaining processes occurring in two classes of crystal solids (metal alloys and doped alkali halides) under irradiation by various types of radiation (alpha, beta, gamma, X-radiations, ions). While metal alloys may differ in high radiation stability, solid solutions based on alkali halides are very radiation-sensitive materials. Radiation defect production mechanisms, intrinsic and extrinsic radiation defects, a role of complexes an impurity-radiation defect which explain distinction in radiating stability of the specified classes of solid solutions are discussed in this e-book. To describe radiation induced phase transformations, two approaches are highlighted: kinetic and thermodynamic. This e-book also includes research on the effect of small radiation doses in a structurally solid phase state of a solution along with a semi-quantitative estimation of radiation effects with respect to temperature changes. This e-book should be a useful reference for advanced readers interested in the physics of radiation and solid state physics.
The geometric formulation of autonomous Hamiltonian mechanics in the terms of symplectic and Poisson manifolds is generally accepted. The literature on this subject is extensive. The present book provides the geometric formulation of non-autonomous mechanics in a general setting of time-dependent coordinate and reference frame transformations. This formulation of mechanics as like as that of classical field theory lies in the framework of general theory of dynamic systems, and Lagrangian and Hamiltonian formalisms on fiber bundles. The reader will find a strict mathematical exposition of non-autonomous dynamic systems, Lagrangian and Hamiltonian non-relativistic mechanics, relativistic mechanics, quantum non-autonomous mechanics, together with a number of advanced models — superintegrable systems, non-autonomous constrained systems, theory of Jacobi fields, mechanical systems with time-dependent parameters, non-adiabatic Berry phase theory, instantwise quantization, and quantization relative to different reference frames.
1.1 Preface Organic chemistry had its origin in chemicals which are synthesized by living cells. These chemicals consist of molecules whose skeletons are built up of carbon atoms. The remaining valences are connected with ligands such as hydrogen, halo gens, -OH,==O, -NH . Some of the skeletal carbon atoms can be replaced by non 2 metals such as oxygen, nitrogen, or sulfur {"heteroatoms"}. It is characteristic for the living world, not to be in a crystalline state. However it is possible to obtain single crystals from many organic compounds both of natural and synthetic origin. For a number of years the physics and chem istry of these crystals have stimulated fundamental research on a rapidly growing scale. The great variety of possible organic structures {as compared to inorganics} opens up a large field of new materials and of novel material properties; for previous literature reviews and data compilations see 1-40) and Chap. 6. The art of producing good and pure organic single crystals has developed hand in-hand with the ever growing requirements of basic research, arising from its interest in fundamental interactions in the solid state. Interactions manifest themselves in a very detailed way by energy transfer.
Geometrical notions and methods play an important role in both classical and quantum field theory, and a connection is a deep structure which apparently underlies the gauge-theoretical models in field theory and mechanics. This book is an encyclopaedia of modern geometric methods in theoretical physics. It collects together the basic mathematical facts about various types of connections, and provides a detailed exposition of relevant physical applications. It discusses the modern issues concerning the gauge theories of fundamental fields. The authors have tried to give all the necessary mathematical background, thus making the book self-contained.This book should be useful to graduate students, physicists and mathematicians who are interested in the issue of deep interrelations between theoretical physics and geometry.
The two books, by authors Andrei Alexandrov and Genadi Petrov, illustrated with many previously unpublished photos, depict the blooming period of the Soviet aviation industry, which owed a great deal of its knowledge to technology derived from German designs.
The two books, by authors Andrei Alexandrov and Genadi Petrov, illustrated with many previously unpublished photos, depict the blooming period of the Soviet aviation industry, which owed a great deal of its knowledge to technology derived from German designs.
Atomic and molecular physics underlie a basis for our knowledge of fundamental processes in nature and technology and in such applications as solid state physics, chemistry and biology. In recent years, atomic and molecular physics has undergone a revolutionary change due to great achievements in computing and experimental techniques. As a result, it has become possible to obtain information both on atomic and molecular characteristics and on dynamics of atomic and molecular processes. This book highlights the present state of investigations in the field of atomic and molecular physics. Recent theoretical developments as well as new discoveries and observations are discussed. The Book should be of interest to students studying atomic and molecular physics and specialists in related fields of science and technology.
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