Gary R. Gray's Books

I'm From

By: Gary R. Gray, Jr.

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A poetic, heartwarming ode to the small, defining moments of a boy's life, by a brilliant new debut and a Caldecott Honoree. A picture book for fans of Last Stop on Market Street. Early morning wake-ups and homemade pancakes, Raucous bus rides and schoolyard games, Family games and bedtime rituals . . . These are the small moments that shape a child's day. I'm From is an invitation into the vivid world of one small boy, a poetic account of all the people and places and things that shape who he is and define where he is from.

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Penguin

Published Date

ISBN 10

1774886170

ISBN 13

9781774886175

Lessons Learned from My Cat Laverne

By: Gary R. Gray

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Lessons Learned from My Cat Laverne

By: Gary R. Gray

It all started at the local animal shelter. My wife, Patty, had gone looking for a cat to adopt when a little tiger cat with a light orange belly bearing dark ocelot spots took up with her. Patty was drawn to the cats sweet little face with the terracotta nose outlined in black. Her golden eyes were completely captivating. Laverne, as she was called, was specialand remarkable. It wasnt just us. Everyone who met her commented on her loving nature, her desire to connect with people, her grace, and her apparent appreciation for everything done for her. We didnt know at the time that she had lymphoma and we would enjoy her company for only a little less than two years. When the diagnosis was confirmed, we were still hopeful she would be able to be with us for a while. As the treatment options began to diminish, I found myself reflecting on the sweet nature of this little kitty and all I was learning from her. Laverne was just being a loving cat, yet she exhibited many sterling traits that we all would do well to emulate. Laverne lived her life well and illustrated the benefits of making friends, establishing connection, expressing appreciation, and maintaining relationships. In this book, you will be drawn to her appealing personality and realize that our small friend had much to teach us about living and loving well.

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WestBow Press

Published Date

ISBN 10

149089389X

ISBN 13

9781490893891

I Took a Chance

By: Gary R. Gray

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I Took a Chance

By: Gary R. Gray

When my sister offered Chance I thought it would be nice to return to the days of my youth when I rode horses. Chance had some issues with his joints and my sister thought he would do better in our area. through out time together he has thrived and we have developed a very special relationship. He can be a real character. This book describes our time together and the bond that has developed.

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WestBow Press

Published Date

ISBN 10

1664291385

ISBN 13

9781664291386

The Political Economy Of Agricultural Trade And Policy

Toward A New Order For Europe And North America

By: Hans J Michelmann,Jack C Stabler,Gary Storey

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The Political Economy Of Agricultural Trade And Policy

Toward A New Order For Europe And North America

By: Hans J Michelmann,Jack C Stabler,Gary Storey

This book presents a descriptive analysis of the political economy of the European Community, the U.S. and Canada. It describes the structural changes and the crises in agriculture and focuses on impact of GATT on agricultural policy and trade in the post-Second World War era.

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199

Publisher

CRC Press

Published Date

ISBN 10

1000304426

ISBN 13

9781000304428

French Philosophy in the Twentieth Century

By: Gary Gutting

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French Philosophy in the Twentieth Century

By: Gary Gutting

A clear and comprehensive account of the history of French philosophy in the twentieth century.

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444

Publisher

Cambridge University Press

Published Date

ISBN 10

0521665590

ISBN 13

9780521665599

Basil Wilson Duke, CSA

The Right Man in the Right Place

By: Gary Robert Matthews

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Basil Wilson Duke, CSA

The Right Man in the Right Place

By: Gary Robert Matthews

The first biography of “one of Kentucky’s best Confederates . . . [who] became a good citizen working for reconciliation between North and South.”—The Post and Courier After practicing law for several years in St. Louis, Basil Wilson Duke (1838-1916) enlisted in the Confederate army in 1861 and was elected first lieutenant of John Hunt Morgan’s legendary cavalry unit. As second in command, he was, Morgan recorded, “wise in counsel, gallant in the field,” and always “the right man in the right place.” Duke was twice wounded in battle and was captured during Morgan’s Great Raid and held prisoner for over a year. When Morgan, who was also Duke’s brother-in-law, was killed in 1864, Duke was promoted to brigadier general and appointed commander of Morgan’s men. Moving to join forces with those of Gen. Joseph E. Johnston’s army in North Carolina, he was assigned to the force escorting Jefferson Davis in his retreat from Richmond at the close of the war. Basil Wilson Duke, CSA, the definitive biography of this important but often overlooked figure in Civil War history, establishes that Duke was in fact the brilliant tactician behind much of the success of Morgan’s cavalry. Author Gary Robert Matthews not only offers an in-depth study of Duke’s celebrated Civil War exploits but also traces his varied postwar literary, legal, and political careers. “Fascinating . . . a vividly written story about a modest Southern gentleman in which the reader may come to his own conclusion that Basil W. Duke was the power behind Morgan’s so-called military genius.”—Edison H. Thomas, author of John Hunt Morgan and His Raiders

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586

Publisher

University Press of Kentucky

Published Date

ISBN 10

0813138256

ISBN 13

9780813138251

More Than a Feeling

Personality, Polarization, and the Transformation of the US Congress

By: Adam J. Ramey,Jonathan D. Klingler,Gary E. Hollibaugh Jr.

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More Than a Feeling

Personality, Polarization, and the Transformation of the US Congress

By: Adam J. Ramey,Jonathan D. Klingler,Gary E. Hollibaugh Jr.

Whatever you think about the widening divide between Democrats and Republicans, ideological differences do not explain why politicians from the same parties, who share the same goals and policy preferences, often argue fiercely about how best to attain them. This perplexing misalignment suggests that we are missing an important piece of the puzzle. Political scientists have increasingly drawn on the relationship between voters’ personalities and political orientation, but there has been little empirically grounded research looking at how legislators’ personalities influence their performance on Capitol Hill. With More Than a Feeling, Adam J. Ramey, Jonathan D. Klingler, and Gary E. Hollibaugh, Jr. have developed an innovative framework incorporating what are known as the Big Five dimensions of personality—openness to experience, conscientiousness, extraversion, agreeableness, and neuroticism—to improve our understanding of political behavior among members of Congress. To determine how strongly individuals display these traits, the authors identified correlates across a wealth of data, including speeches, campaign contributions and expenditures, committee involvement, willingness to filibuster, and even Twitter feeds. They then show how we might expect to see the influence of these traits across all aspects of Congress members’ political behavior—from the type and quantity of legislation they sponsor and their style of communication to whether they decide to run again or seek a higher office. They also argue convincingly that the types of personalities that have come to dominate Capitol Hill in recent years may be contributing to a lot of the gridlock and frustration plaguing the American political system.

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263

Publisher

University of Chicago Press

Published Date

ISBN 10

022645598X

ISBN 13

9780226455983

Behavior, Health, and Environmental Stress

By: Sheldon Cohen,Gary W. Evans,Daniel Stokols,David S. Krantz

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Behavior, Health, and Environmental Stress

By: Sheldon Cohen,Gary W. Evans,Daniel Stokols,David S. Krantz

Eight years ago, four psychologists with varying backgrounds but a common in terest in the impact of environmental stress on behavior and health met to plan a study of the effects of aircraft noise on children. The impetus for the study was an article in the Los Angeles Times about architectural interventions that were planned for several noise-impacted schools under the air corridor of Los Angeles Interna tional Airport. These interventions created an opportunity to study the same chil dren during noise exposure and then later after the exposure had been attenuated. The study was designed to test the generality of several noise effects that had been well established in laboratory experimental studies. It focused on three areas: the relationship between noise and personal control, noise and attention, and noise and cardiovascular response. Two years later, a second study, designed to replicate and extend findings from the first, was conducted.

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288

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1475793804

ISBN 13

9781475793802

National Geographic Guide to America's Outdoors New England

Nature Adventures in Parks Preserves Forests Wildlife Refuges Wilderness Are

By: Gary Ferguson

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National Geographic Guide to America's Outdoors New England

Nature Adventures in Parks Preserves Forests Wildlife Refuges Wilderness Are

By: Gary Ferguson

For New England, "nature adventures in parks, preserves, forests, wildlife refuges, wilderness areas"--Cover.

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292

Published Date

ISBN 10

0792277422

ISBN 13

9780792277422

Pharmacotherapy A Pathophysiologic Approach 9/E

By: Joseph T. DiPiro,Robert L. Talbert,Gary C. Yee,Barbara G. Wells,L. Michael Posey

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Pharmacotherapy A Pathophysiologic Approach 9/E

By: Joseph T. DiPiro,Robert L. Talbert,Gary C. Yee,Barbara G. Wells,L. Michael Posey

25 ADDITIONAL CHAPTERS AVAILABLE ONLINE THE LANDMARK TEXT ON HOW TO ACHIEVE OPTIMAL PATIENT OUTCOMES THROUGH EVIDENCE-BASED MEDICATION THERAPY Pharmacotherapy: A Pathophysiologic Approach is written to help you advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. You will find everything you need to provide safe, effective drug therapy across the full range of therapeutic categories. This edition is enriched by more than 300 expert contributors, and every chapter has been revised and updated to reflect the latest evidence-based information and recommendations. Important features such as Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy make this text an essential learning tool for students, patient-focused pharmacists, and other health care providers. NEW TO THIS EDITION: A section on personalized pharmacotherapy appears in most sections All diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches have been updated in full color to clearly distinguish treatment pathways New drug monitoring tables have been added Most of the disease-oriented chapters have incorporated evidence-based treatment guidelines that often include ratings of the level of evidence to support the key therapeutic approaches Twenty-five online-only chapters are available at www.pharmacotherapyonline.com

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2629

Publisher

McGraw Hill Professional

Published Date

ISBN 10

0071800549

ISBN 13

9780071800549

Pharmacotherapy

A Pathophysiologic Approach, Eighth Edition

By: Joseph T. DiPiro,Robert L. Talbert,Gary C. Yee,Gary R. Matzke,Barbara G. Wells,L. Michael Posey

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Pharmacotherapy

A Pathophysiologic Approach, Eighth Edition

By: Joseph T. DiPiro,Robert L. Talbert,Gary C. Yee,Gary R. Matzke,Barbara G. Wells,L. Michael Posey

The landmark text on how to achieve optimal patient outcomes through evidence-based medication therapy Pharmacotherapy: A Pathophysiologic Approach is written to help you advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. You will find everything you need to provide safe, effective drug therapy across the full range of therapeutic categories. This edition is enriched by more than 300 expert contributors, and every chapter has been revised and updated to reflect the latest in evidence-based information and recommendations. Important features such as Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy make this text an essential learning tool for students, patient-focused pharmacists, and other health care providers. NEW TO THIS EDITION A section on personalized pharmacotherapy appears in most sections All diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches have been updated in full color to clearly distinguish treatment pathways New drug monitoring tables have been added Most of the disease-oriented chapters have incorporated evidence-based treatment guidelines that when available, include ratings of the level of evidence to support the key therapeutic approaches Twenty-four online-only chapters

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2705

Publisher

McGraw Hill Professional

Published Date

ISBN 10

0071784993

ISBN 13

9780071784993

Pharmacotherapy: A Pathophysiologic Approach, Tenth Edition

By: Joseph T. DiPiro,Robert L. Talbert,Gary C. Yee,Gary R. Matzke,Barbara G. Wells,L. Michael Posey

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Pharmacotherapy: A Pathophysiologic Approach, Tenth Edition

By: Joseph T. DiPiro,Robert L. Talbert,Gary C. Yee,Gary R. Matzke,Barbara G. Wells,L. Michael Posey

The most comprehensive text available on the use of evidence-based medication therapies for optimal patient outcomes – updated with the latest breakthroughs and guidelines A Doody's Core Title for 2019! Pharmacotherapy: A Pathophysiologic Approach is written to help you advance the quality of patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. The scope of this trusted classic goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. You will find everything you need to provide safe, effective drug therapy across the full range of therapeutic categories. Presented in full-color, the Tenth Edition is enriched by more than 300 expert contributors, and every chapter has been updated to reflect the latest in evidence-based information and recommendations. This sweeping updates include tables, charts, algorithms, and practice guidelines. This edition is also enhanced by a timely all-new chapter on Travel Health. Here’s why this is the perfect learning tool for students, patient-focused pharmacists, and other health care providers: • All chapters have been updated to provide the most current, reliable, and relevant information possible • Key Concepts at the beginning of each chapter • Clinical Presentation Tables summarize disease signs and symptoms • Clinical Controversies Boxes examine the complicated issues faced by students and clinicians in providing drug therapy • Color coded diagnostic flow diagram, treatment algorithms, dosing recommendations, and monitoring approaches clearly distinguish treatment pathways • Most disease-oriented chapters include updated evidence-based treatment guidelines that often include ratings of the level of evidence to support the key therapeutic approaches Edition after trusted edition, Pharmacotherapy: A Pathophysiologic Approach has been unmatched in its ability to clearly and impartially impart core pathophysiological and therapeutic elements that students and practitioners must be familiar with.

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2509

Publisher

McGraw Hill Professional

Published Date

ISBN 10

1259587495

ISBN 13

9781259587498

Dual Momentum Investing: An Innovative Strategy for Higher Returns with Lower Risk

By: Gary Antonacci

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Dual Momentum Investing: An Innovative Strategy for Higher Returns with Lower Risk

By: Gary Antonacci

The investing strategy that famously generates higher returns with substantially reduced risk--presented by the investor who invented it "A treasure of well researched momentum-driven investing processes." Gregory L. Morris, Chief Technical Analyst and Chairman, Investment Committee of Stadion Money Management, LLC, and author of Investing with the Trend Dual Momentum Investing details the author’s own momentum investing method that combines U.S. stock, world stock, and aggregate bond indices--a formula proven to dramatically increase profits while lowering risk. Antonacci reveals how momentum investors could have achieved long-run returns nearly twice as high as the stock market over the past 40 years, while avoiding or minimizing bear market losses--and he provides the information and insight investors need to achieve such success going forward. His methodology is designed to pick up on major changes in relative strength and market trend. Gary Antonacci has over 30 years experience as an investment professional focusing on under exploited investment opportunities. In 1990, he founded Portfolio Management Consultants, which advises private and institutional investors on asset allocation, portfolio optimization, and advanced momentum strategies. He writes and runs the popular blog and website optimalmomentum.com. Antonacci earned his MBA at Harvard.

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238

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McGraw Hill Professional

Published Date

ISBN 10

0071849459

ISBN 13

9780071849456

Pharmacotherapy: A Pathophysiologic Approach, Eleventh Edition

By: Joseph T. DiPiro,Gary C. Yee,L. Michael Posey

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Pharmacotherapy: A Pathophysiologic Approach, Eleventh Edition

By: Joseph T. DiPiro,Gary C. Yee,L. Michael Posey

Publisher's Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product. 25+ additional chapters available online! The classic guide to driving optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines Presented in full color, Pharmacotherapy: A Pathophysiologic Approach, 11th Edition helps you deliver the highest-quality patient care through evidence-based medication therapy derived from sound pharmacotherapeutic principles. It takes you beyond drug indications and dosages, showing how to properly select, administer, and monitor drugs—everything you need to provide safe, effective drug therapy across all therapeutic categories. With all-new monitoring tables and authoritative content from 300 expert contributors, this new edition has been fully updated to reflect the latest evidence-based information and recommendations. You’ll find Key Concepts at the beginning of each chapter, Clinical Presentation tables that summarize disease signs and symptoms, and Clinical Controversies boxes that examine the complicated issues faced by students and clinicians in providing drug therapy. Why Pharmacotherapy: A Pathophysiologic Approach is perfect for students, pharmacists, and other healthcare providers: • All chapters provide the most current, reliable, and relevant information available. • Key concepts kick off every chapter. • Clinical Presentation Tables summarize disease signs and symptoms. • The majority of sections include personalized pharmacotherapy content. • Clinical Controversies Boxes clarify the most complex drug therapy issues you’ll face. • Diagnostic flow diagrams, treatment algorithms, dosing recommendations, and monitoring approaches have been updated in full color to distinguish treatment pathways. • Most disease-oriented chapters are enhanced by updated evidence-based treatment guidelines, which often include ratings of the level of evidence to support key therapeutic approaches. • Instructors who adopt this text are eligible for a PowerPoint presentation of all images and answers to Self-Assessment Questions! The most trusted guide of its kind for decades, Pharmacotherapy: A Pathophysiologic Approach is the go-to text for students and practitioners seeking clear, objective coverage of core pathophysiologic and therapeutic elements.

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2672

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McGraw Hill Professional

Published Date

ISBN 10

1260116824

ISBN 13

9781260116823

DiPiro's Pharmacotherapy: A Pathophysiologic Approach, 12th Edition

By: Joseph T. DiPiro,Gary C. Yee,Stuart T. Haines,Thomas D. Nolin,Vicki Ellingrod,L. Michael Posey

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DiPiro's Pharmacotherapy: A Pathophysiologic Approach, 12th Edition

By: Joseph T. DiPiro,Gary C. Yee,Stuart T. Haines,Thomas D. Nolin,Vicki Ellingrod,L. Michael Posey

A Doody's Core Title for 2023! The #1 Textbook in Pharmacotherapy providing optimal patient outcomes using evidence-based medication therapies—updated with the latest advances and guidelines For more than 30 years, DiPiro’s Pharmacotherapy has been the essential textbook for learning how to properly select, administer, and monitor drugs―everything needed to provide safe, effective drug therapy across all therapeutic categories. This new edition has been fully updated with the latest evidence-based information and recommendations. With content from 300 expert contributors, this valuable resource offers detailed descriptions of common and uncommon disease states, including treatment by pharmacologic and non-pharmacologic means. Each disease chapter opens with a Patient Care Process, helping readers understand the collaborative care model in which pharmacists work and communicate with other healthcare providers for effective coordinated care. Here's why DiPiro's Pharmacotherapy: A Pathophysiologic Approach is the perfect learning tool for students, pharmacists, and other healthcare providers: All chapters provide the most current, reliable, and relevant information available Key concepts are included at the beginning of each chapter Clinical Presentation boxes concisely outline disease signs and symptoms New: Beyond the Book feature points readers to multimedia resources to deepen their understanding of the material Diagnostic flow diagrams, treatment algorithms, dosing guideline recommendations, and monitoring approaches clearly distinguish treatment pathways New: Drug monitoring tables have been added Patient care process boxes help readers know how to communicate with other health care providers New: Additional FREE E-Chapters are available on AccessPharmacy New: Over 2000 Review Questions to help prepare students!

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3439

Publisher

McGraw Hill Professional

Published Date

ISBN 10

1265473420

ISBN 13

9781265473426

Koneman's Color Atlas and Textbook of Diagnostic Microbiology

By: Gary W. Procop,Deirdre L. Church,Geraldine S. Hall,William M. Janda

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Koneman's Color Atlas and Textbook of Diagnostic Microbiology

By: Gary W. Procop,Deirdre L. Church,Geraldine S. Hall,William M. Janda

Now in striking full color, this Seventh Edition of Koneman’s gold standard text presents all the principles and practices readers need for a solid grounding in all aspects of clinical microbiology—bacteriology, mycology, parasitology, and virology. Comprehensive, easy-to-understand, and filled with high quality images, the book covers cell and structure identification in more depth than any other book available. This fully updated Seventh Edition is enhanced by new pedagogy, new clinical scenarios, new photos and illustrations, and all-new instructor and student resources.

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Page Count

1964

Publisher

Jones & Bartlett Learning

Published Date

ISBN 10

1284322378

ISBN 13

9781284322378

Into the Stillness

Dialogues on Awakening Beyond Thought

By: Gary Weber,Richard Doyle

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Into the Stillness

Dialogues on Awakening Beyond Thought

By: Gary Weber,Richard Doyle

At once extraordinarily wide-ranging and sharply focused, Into the Stillness offers several deceptively simple and informal conversations about life, existence, and identity in one book. This is an important book. Don’t be misled by the casually graceful repartee and lightness of touch. Without dogma, without heavy shoulds and should nots, authors Gary Weber and Richard Doyle point toward something eternal, framed in our twenty-first-century understanding of neuroscience, spirituality, and something that arises from, and returns to, the Stillness and the Silence. In Into the Stillness, Weber and Doyle offer a practical investigation and guidance toward “the sweetest, fullest, most loving, caring, and manifesting experience that anyone could ever wish for.” Chapter headings include “Using dialogue for awakening,” “Can you ‘do nothing’ and awaken?”, “Why do we fear emptiness, silence, and stillness?”, and “Functioning without thoughts: sex, psychedelics, and non-duality.” As a journey, this collection of dialogues is inspiring, shifting, and full of little moments of insight that will linger for a long time afterward.

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208

Publisher

New Harbinger Publications

Published Date

ISBN 10

1626257426

ISBN 13

9781626257429

Handbook of Grignard Reagents

By: Gary S. Silverman,Philip E. Rakita

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Handbook of Grignard Reagents

By: Gary S. Silverman,Philip E. Rakita

This handbook provides the theoretical and practical information necessary to explore new applications for Grignard reagents on a day-to-day basis, presenting a comprehensive overview of current research activities in Grignard chemistry. This book surveys specific reactions and applications of Grignard reagents, organized by type of substrate and t

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732

Publisher

CRC Press

Published Date

ISBN 10

1482273373

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9781482273373

Dreams in the New Century

Instant Cities, Shattered Hopes, and Florida’s Turning Point

By: Gary R. Mormino

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Dreams in the New Century

Instant Cities, Shattered Hopes, and Florida’s Turning Point

By: Gary R. Mormino

Florida Book Awards, Gold Medal for Florida Nonfiction Florida Historical Society Charlton Tebeau Book Award A leading Florida historian explores one of the state’s most consequential eras It was a time of stunning episodes of boom and bust, an era of extremes, a decade of historic changes that point to Florida’s future. In this book, eminent historian Gary Mormino illuminates early twenty-first-century Florida and its connections to some of the most significant events in contemporary American history. Following Mormino’s milestone work Land of Sunshine, State of Dreams, which details the dynamic history of Florida from 1950 to 2000, Dreams in the New Century explores the state’s tumultuous next chapter, a period that included the Bush v. Gore election, 9/11, the housing bubble and Great Recession, and the election of Barack Obama. During these years the Elián González story engrossed the country, Tim Tebow rose to football fame, and Donald Trump became a Florida celebrity. From hurricanes to Ponzi schemes, red tides, climate change, the “Stand-Your-Ground” gun law, demographic diversity, and more, Florida offered nonstop news fodder that reflected its extraordinary internal trends and its importance in the nation. As Mormino shows, Florida is a place of deep conflicts—North and South, liberal and conservative, newcomer and local, growth and conservation—with histories that can be traced back centuries. In 2000‒2010, Mormino argues, these tensions collided to produce a “Big Bang” that will continue to resonate in years to come. Mormino takes stock of this crucible of change and explains the social, cultural, and political intricacies of a state the world struggles to understand. Dreams in the New Century unravels Florida’s complicated recent history in a gripping, informative, and fascinating narrative.

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497

Publisher

University Press of Florida

Published Date

ISBN 10

081307231X

ISBN 13

9780813072319

Mosby's Paramedic Textbook

By: Mick J. Sanders,Lawrence M. Lewis,Gary Quick,Kim McKenna

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Mosby's Paramedic Textbook

By: Mick J. Sanders,Lawrence M. Lewis,Gary Quick,Kim McKenna

This new edition provides complete coverage of prehospital care in a single, comprehensive text. It explains the paramedic's role, the unique characteristics of prehospital care & emergency care of acutely ill & traumatically injured patients.

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1787

Publisher

Jones & Bartlett Publishers

Published Date

ISBN 10

0323072755

ISBN 13

9780323072755

The Development of Iron Chelators for Clinical Use

By: Raymond J. Bergeron,Gary M. Brittenham

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The Development of Iron Chelators for Clinical Use

By: Raymond J. Bergeron,Gary M. Brittenham

Representing an integration of basic and clinical sciences, this book focuses on new concepts in the design, synthesis, and testing of iron chelators for clinical application. It provides an overview of the pathophysiology of iron metabolism as it relates to the origins of iron-mediated tissue damage, and it clearly outlines successes and shortcomings of current iron chelation therapy in preventing such damage. The book also describes a number of other exciting potential therapeutic applications of iron chelators, such as in the treatment of malaria. Other topics covered include iron coordination chemistry, recent advances in synthetic methods for accessing iron chelators, siderophore models, subcellular iron storage targets, and the possible application of biotechnology in the production of therapeutically useful iron chelators. The book also describes new animal models for evaluating chelators.

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