The basic principle of all molecular genetic methods is to employ inherited, discrete and stable markers to identify genotypes that characterize individuals, populations or species. Such genetic data can provide information ori the levels and distribution of genetic variability in relation to mating patterns, life history, population size, migration and environment. Although molecular tools have long been employed to address various questions in fisheries biology and management, their contributions to the field are sometimes unclear, and often controversial. Much of the initial impetus for the deployment of molecular markers arose from the desire to assess fish stock structure based on various interpretations of the stock concept. Although such studies have met with varying success, they continue to provide an impetus for the development of increasingly sensitive population discriminators, yielding information that can be valuable for both sustainable exploitation and the conservation of fish populations. In the last major synthesis of the subject, Ryman and Utter (1987) summarized progress and applications, though this was prior to the wide-scale adoption of DNA methodology. New sources of genetic markers and protocols are now available, in particular those that exploit the widely distributed and highly variable repeat sequences of DNA, and the amplification technique of the polymerase chain reaction.
Provides the clinician with information about causation, complications, natural course, and management of GERD. The efficacy, safety, and suggested regimens of pharmacologic therapies are discussed. Data on the relationship between GERD and asthma are presented. The clinical presentation of GERD patients with chronic cough and laryngitis is discussed in detail.
The benchmark evidence-based pharmacotherapy text-now in full color! Additional chapters are available online When it comes to helping you develop a mastery of evidence-based medicine for optimal patient outcomes, no book can match Pharmacotherapy: A Pathophysiologic Approach. Like the discipline it covers, the scope of this trusted resource goes beyond drug indications and dosages to include the initial selection, proper administration, and monitoring of drugs. The book also delves into psychosocial issues that affect compliance ... topics related to a patient's ability to understand and manage often-complex therapy... and lifestyle changes that may reduce the need for drug therapy or improve pharmacotherapeutic outcomes. Pharmacotherapy delivers everything you need to provide safe, efficacious drug therapy across the full range of therapeutic categories. FEATURES NEW! Expanded evidence-based recommendations NEW! Extended coverage of the timely issue of palliative care and pain medicine NEW! Important chapters on Pulmonary Hypertension, Disorders of Calcium and Phosphorus Homeostasis, and Multiple Myeloma, Outstanding pedagogy, including: “Key Concepts” highlighted in each chapter “Clinical Presentation” boxes summarize the most common disease signs and symptoms covered in each chapter “Clinical Controversies” boxes-presented in the Treatment sections of the disease-oriented chapters-examine the complicated issues faced by students and clinicians in providing drug therapy Clear therapeutic recommendations in each disease-specific chapter “Evaluation of Therapeutic Outcomes” boxes in each disease-specific chapter, containing key monitoring guidelines that facilitate the development of a pharmaceutical, nursing, or medical care plan
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