This book will strengthen the knowledge of mechanistic organic chemistry for organic chemists who have completed a bachelor’s degree and want to start researching in a laboratory or working in a chemical company. Hardly ever does an organic synthesis advance according to plan. Diligently designed synthetic schemes stumble upon the laboratory reality of meagre yields, side reactions, and unwanted products. To fight against that we have a magnificent intellectual tool: reaction mechanisms. In the course of an undergraduate degree, the student assimilates an assortment of unadorned reaction mechanisms, when in professional practice she/he needs to envision convoluted mechanisms resulting from the sequential operation of simple steps. The student here is like the novice chess player who knows how to move the pieces, but not how to play the game. This book facilitates that learning in mechanistic organic chemistry, a fundamental apprenticeship for the preparation of new drugs that save millions of lives.
The aim of this book is to help people performing routine operations in Organic Synthesis in a laboratory. This book, the first one in a series, focuses on the oxidation of alcohols to aldehydes and ketones. Probably, this is the most important routine operation in Organic Synthesis.
As the second volume in a comprehensive encyclopedia of organic reactions, this work provides an elaborated description of the experimental methods used for the oxidation of alcohols to acids. It supplies important data on possible interferences from protecting groups and functional groups, as well as on potential side-reactions. This book is a must for anyone involved in the preparation of organic compounds.
The aim of this book is to help people performing routine operations in Organic Synthesis in a laboratory. This book, the first one in a series, focuses on the oxidation of alcohols to aldehydes and ketones. Probably, this is the most important routine operation in Organic Synthesis.
As the second volume in a comprehensive encyclopedia of organic reactions, this work provides an elaborated description of the experimental methods used for the oxidation of alcohols to acids. It supplies important data on possible interferences from protecting groups and functional groups, as well as on potential side-reactions. This book is a must for anyone involved in the preparation of organic compounds.
This book will strengthen the knowledge of mechanistic organic chemistry for organic chemists who have completed a bachelor’s degree and want to start researching in a laboratory or working in a chemical company. Hardly ever does an organic synthesis advance according to plan. Diligently designed synthetic schemes stumble upon the laboratory reality of meagre yields, side reactions, and unwanted products. To fight against that we have a magnificent intellectual tool: reaction mechanisms. In the course of an undergraduate degree, the student assimilates an assortment of unadorned reaction mechanisms, when in professional practice she/he needs to envision convoluted mechanisms resulting from the sequential operation of simple steps. The student here is like the novice chess player who knows how to move the pieces, but not how to play the game. This book facilitates that learning in mechanistic organic chemistry, a fundamental apprenticeship for the preparation of new drugs that save millions of lives.
A rich new source of important archival information, Voices from Vilcabamba examines the fall of the Inca Empire in unprecedented detail. Containing English translations of seven major documents from the Vilcabamba era (1536–1572), this volume presents an overview of the major events that occurred in the Vilcabamba region of Peru during the final decades of Inca rule. Brian S. Bauer, Madeleine Halac-Higashimori, and Gabriel E. Cantarutti have translated and analyzed seven documents, most notably Description of Vilcabamba by Baltasar de Ocampo Conejeros and a selection from Martín de Murúa’s General History of Peru, which focuses on the fall of Vilcabamba. Additional documents from a range of sources that include Augustinian investigations, battlefield reports, and critical eyewitness accounts are translated into English for the first time. With a critical introduction on the history of the region during the Spanish Conquest and introductions to each of the translated documents, the volume provides an enhanced narrative on the nature of European-American relations during this time of important cultural transformation.
Organizing Words presents a series of essays on some 220 widely used--and much debated--terms in the social sciences, and organization studies. Each essay explores the meanings and uses of the word; and also the controversies they have sparked. The book aims to be a first port of call for students, researchers and scholars who wish to familiarize themselves with these key ideas and use them in their own work. The book is neither an encyclopaedia nor a dictionary, but a thesaurus. As such it combines both the original meaning of a thesaurus as a treasure trove, with its more contemporary characteristics of an accessible and practical resource. Primarily aimed to those interested in social and organizational studies, it will appeal to all those interested in the human sciences. It does not claim to be canonical or all-inclusive, but each entry seeks to enlighten and help, without patronizing or obscuring disagreements and difficulties. The book seeks to be re-assuring without being complacent or "comfortable", to be authoritative without being doctrinaire, and to be critical without being destructive. Words help us express ourselves, and make sense of our experiences and our actions; and they help us to organize ourselves, our thoughts and our universe. Organizing Words will be an invaluable resource for essay-writing and a useful tool in planning and carrying out projects and dissertations. Most of the entries have been written by Yiannis Gabriel, with 40 essays coming from experts in particular areas.
Over the last three decades the historian Gabriel Kolko has redefined the way we look at modern warfare and its social and political effects. Century of War gives us a masterly synthesis of the effects of war on civilian populations and the political results of these traumatizing experiences in the twentieth century.
The authors interviewed over 5,000 citizens in Germany, Italy, Mexico, Great Britain, and the U.S. to learn political attitudes in modem democratic states. Originally published in 1963. The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
This fascinating book provides a fully integrated explanation of the history of the modern world. Although the sheer complexity of society requires that it be studied from the standpoint of several social sciences (including Economics, Political Science, Sociology and Anthropology), using only the tools of just one of these is an obstacle to understanding the whole society, where social, economic and political conditions are interacting all the time. The book explains why and how modern communities have evolved from their pre-modern, Ancien regime, states in the early eighteenth century, to the early twenty-first century, where economic development had reached unprecedented levels. It shows that political revolutions have preceded economic revolutions, rather than the reverse, although there is a considerable degree of interaction between macroeconomic and political variables. Economic histories of the period neglect non-economic factors such as political and legal institutions, which from a wide perspective have a powerful impact on economic developments. The complexity of the world and of the times in which we live is overwhelming and growing. Professor Tortella provides an international approach and combines economic and social analysis with political, cultural, and scientific issues. Topics covered include: the Industrial Revolution capitalism and the West the First and Second World War the rise of communism and the era of Stalin the US depression and the Gold Standard social and class struggle
Frederick R. Gabriel graduated from medical school in 1940, entered the US Army, and was assigned to the newly-created 39th Station Hospital. His letters from the Pacific theater—especially from Guadalcanal, Angaur, and Saipan—capture the everyday life of a soldier physician. His son, Michael P. Gabriel, a professional historian, has faithfully preserved, edited, and annotated that correspondence to add a new dimension to our understanding of the social history of World War II, which he presents here in Physician Soldier: The South Pacific Letters of Captain Fred Gabriel from the 39th Station Hospital. Like most wartime hospitals, the 39th Station Hospital was positioned in a rear area and saw limited direct action. And like most wartime hospitals, the 39th Station Hospital spent each day confronting the injuries and casualties of frontline combat. Gabriel supervised a ward and oversaw the unit’s laboratory, serving a hospital that provided care to four hundred patients at a time. Gabriel’s letters home capture this experience and more, providing a revealing look into day-to-day life in the Pacific theater. He discusses the training of medical officers and female nurses, recreational activities such as Bob Hope’s USO show, and even his thoughts on the death of FDR, the end of the war in Europe, and ultimately the horrors of the atomic bomb.
At first glance, Garcia Mrquez's vivid and detailed portrait of his early life appears to be testament to a photographic memory. Yet as he explains in the epigraph, "Life isn't what one lived, but what one remembers and how one remembers it to tell it.
Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases. An ideal balance of the basic science you need to know and how to apply that information to clinical practice. An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases. New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. More schematic diagrams clearly summarize information and facilitate understanding.
Kelley's Textbook of Rheumatology delivers the state-of-the-art scientific and clinical know-how you need to offer your patients the most effective diagnosis and care. This rheumatology book’s sweeping updates highlight current advances and breakthroughs that impact your practice. With Kelley's Textbook of Rheumatology, you'll be ready to handle the toughest clinical challenges you face. Search the entire contents online at www.expertconsult.com, download all of images, and watch videos demonstrating the complete musculoskeletal exam, including abnormal findings and the arthroscopic presentation of diseased joints. Review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance with the integrated chapter format that readers of Kelley's Textbook of Rheumatology have always appreciated. Gain a thorough understanding of the "whys" and "hows" of rheumatic disease management with detailed coverage of the very latest breakthroughs and the newest clinical algorithms. Apply the latest therapeutic advances through new chapters in bioengineering and tissue engineering, as well as up-to-date coverage of gout and disease-modifying drugs. Learn how the study of biomarkers across populations can help you detect diseases earlier and with greater accuracy with a new chapter on epigenetics. Diagnose, monitor, and manage rheumatic disease more effectively with expanded information on the use of ultrasound and other imaging modalities.
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