This updated text brings together the principles & applications of epidemiology, the main health problems experienced by populations & the main groups within them, the strategies for intervention to promote health & prevent disease, the themes underlying health policy formulation & a description of the provision of health services.
This updated text brings together the principles & applications of epidemiology, the main health problems experienced by populations & the main groups within them, the strategies for intervention to promote health & prevent disease, the themes underlying health policy formulation & a description of the provision of health services.
This book summarizes major aspects of the evolution of South American metatherians, including their epistemologic, phylogenetic, biogeographic, faunal, tectonic, paleoclimatic, and metabolic contexts. A brief overview of the evolution of each major South American lineage ("Ameridelphia", Sparassodonta, Didelphimorphia, Paucituberculata, Microbiotheria, and Polydolopimorphia) is provided. It is argued that due to physiological constraints, metatherian evolution closely followed the conditions imposed by global temperatures. In general terms, during the Paleocene and the early Eocene multiple radiations of metatherian lineages occurred, with many adaptive types exploiting insectivorous, frugivorous, and omnivorous adaptive zones. In turn, a mixture of generalized and specialized types, the latter mainly exploiting carnivorous and granivorous-folivorous adaptive zones, characterized the second half of the Cenozoic. In both periods, climate was the critical driver of their radiation and turnovers.
Through 10 outstanding editions, Kelley & Firestein’s Textbook of Rheumatology has provided authoritative, in-depth guidance in rheumatology with an ideal balance of basic science and clinical application. The 11th Edition of this classic text continues this tradition of excellence, while keeping you abreast of recent advances in genetics and the microbiome, new therapies such as biologics and biosimilars, and other rapid changes in the field. It provides comprehensive, global coverage of all aspects of diagnosis, screening, and treatment in both adults and children, in a user-friendly, full color reference. Covers everything from basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes—including key data on therapeutic outcomes to better inform clinical decision making. Includes new chapters on Innate Lymphoid Cells and Natural Killer Cells, Pathogenesis of Inflammasome Mediated Diseases, Bisphosphonates, Ultrasound Evaluation of the Musculoskeletal System, and Evaluation of Monoarticular and Polyarticular Arthritis. Features 1,200 high-quality illustrations, including superb line art, quick-reference tables, and full-color clinical photographs. Shares the knowledge and expertise of internationally renowned scientists and clinicians, including new editor Dr. Gary Koretzky, specialist in immunology and rheumatology. Demonstrates the complete musculoskeletal exam in online videos, including abnormal findings and the arthroscopic presentation of diseased joints.
The book shows that self-help in commercial law is a fast, inexpensive and efficient alternative to court enforcement. Self-help remedies and private debt collection are largely but not exclusively features of common law jurisdictions, since remnants of private enforcement can still be found in contract law in civilian systems. The book argues that – despite their usefulness – self-help and private debt collection entail significant risks, especially for consumer debtors. This means that private enforcement needs to be accompanied by the introduction of tailor-made consumer-debtor protection regulation. Specific attention is given to factoring, which functions in many instances as a form of pseudo-private debt collection and which has been exploited to bypass sector-specific consumer protection regulations.
Consult the definitive resource in rheumatology for an in-depth understanding of scientific advances as they apply to clinical practice. Masterfully edited by Drs. Gary S. Firestein, Ralph C. Budd, Sherine E. Gabriel, Iain B. McInnes, and James R. O'Dell, and authored by internationally renowned scientists and clinicians in the field, Kelley and Firestein’s Textbook of Rheumatology, 10th Edition, delivers the knowledge you need for accurate diagnoses and effective patient care. From basic science, immunology, anatomy, and physiology to diagnostic tests, procedures, and specific disease processes, this state-of-the-art reference provides a global, authoritative perspective on the manifestations, diagnosis and treatment of rheumatic diseases. An ideal balance of the basic science you need to know and how to apply that information to clinical practice. An integrated chapter format allows you to review basic science advances and their clinical implications in one place and get dependable, evidence-based guidance for the full range of rheumatologic diseases and syndromes. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. New content on the latest diagnostic perspectives and approaches to therapy, including five brand-new chapters: Metabolic Regulation of Immunity, Principles of Signaling, Research Methods in the Rheumatic Diseases, Novel Intracellular Targeting Agents, and IgG4-Related Diseases. New and expanded chapter topics on small molecule treatment, biologics, biomarkers, epigenetics, biosimilars, and cell-based therapies. More schematic diagrams clearly summarize information and facilitate understanding.
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