One outstanding question in biology is the problem of devel opment: how the genetic instructions encoded in the DNA become expressed in the morphological, physiological, and behavioral features of multicellular organisms, through an ordered sequence of events that extend from the first cell division of the zygote to the adult stage and eventual death. The problem is how a one dimensional array of instructions is transformed into a four dimensional entity, the organism that exists in space and time. Understanding this transformation is, nevertheless, necessary for mastering the process of evolution. One hundred and twenty-five years after The Origin of Species, we have gained some understanding of evolution at the genetic level. Genetic information is stored in the linear sequence of nucleotides in the DNA. Gene mutations, chromosomal reorganiza tions, and a host of related processes introduce variation in the sequence and the amount of DNA. The fate of these variations is determined by interactions within the genome and with the outside environment that are largely understood. We have recently gained a glimpse of how the genome of eukaryotes is organized and will learn much more about it in the future, now that we have the research tools for it.
In anticipation of the opening of the H. Lee Moffitt Cancer Center and Research lnstitut~ on the campus of the University of South Florida, an international symposium, "The First Annual H. Lee Moffitt Symposium on Cancer Biology and Therapeutics" was held in Tampa, Florida on January 20-22, 1986. In this first symposium we decided to present a broad-based series of topics dealing with the major issues in the field of cancer. These topics ranged from the biochemistry of the cancer cell to the design of antineoplastic agents, through tumor cell heterogeneity, treatment of ltuman neoplasms to immunological aspects of cancer biology and tr~atment. The speakers chosen represented individuals of international acclaim who are very active in the area of cancer research and treatment. The symposium brought together scien tists/physicians from six nations including Austria, Canada, France, Hungary, West Germany, and of course, the United States. The congeniality of the participants promoted the friendly exchange of knowledge which, it is hoped, will greatly hasten the time when successful management of human cancer will become routine. Future symposia in this series will be highly focused and will deal with a single facet of this vast field of cancer research and treatment. Joseph G. Cory, Editor Andor Szentivanyi, Editor University of South Florida, 1986 V ACKNOWLEDGMENTS This volume presents the Proceedings of the H. Lee Moffitt International Syn~osium on Cancer Biology and Therapeutics which was held in Tampa, Florida on January 20, 21, and 22, 1986.
The 13th Annual Meeting of the Foundation was held in Edinburgh during September 1985. The subject was neuroendocrine molecular biology which brought together leading scientists in the fields of molecular genetics, neuroendocrinology and developmental neuro biology. The conference was most stimulating and as the Proceedings show, novel data presented was of the highest quality. The topics presented were grouped under the headings;, "Molecular Biology of the Nervous System", ''IlIRH - New Perspectives', ''Neuropeptides'', "Oxytocin and Vasopressin", "Transcriptional and Post-Translational Regulation of Neuropeptide Synthesis", "Neuroendocrine Mechanisms at the Cellular Level", "Receptors - Cellular and Molecular Biology" and "Clinical Applications". The
Introduction to UAV Systems The latest edition of the leading resource on unmanned aerial vehicle systems In the newly revised Fifth Edition of Introduction to UAV Systems, an expert team of aviators, engineers, and researchers delivers the fundamentals of UAV systems for both professionals and students in UAV courses. Suitable for students in Aerospace Engineering programs, as well as Flight and Aeronautics programs, this new edition now includes end-of-chapter questions and online instructor ancillaries that make it an ideal textbook. As the perfect complement to the author’s Design of Unmanned Aerial Systems, this book includes the history, classes, and missions of UAVs. It covers fundamental topics, like aerodynamics, stability and control, propulsion, loads and structures, mission planning, payloads, and communication systems. Brand-new materials in areas including autopilots, quadcopters, payloads, and ground control stations highlight the latest industry technologies. The authors also discuss: A thorough introduction to the history of unmanned aerial vehicles, including their use in various conflicts, an overview of critical UAV systems, and the Predator/Reaper A comprehensive exploration of the classes and missions of UAVs, including several examples of UAV systems, like Mini UAVs, UCAVs, and quadcopters Practical discussions of air vehicles, including coverage of topics like aerodynamics, flight performance, stability, and control In-depth examinations of propulsion, loads, structures, mission planning, control systems, and autonomy Perfect for professional aeronautical and aerospace engineers, as well as students and instructors in courses like Unmanned Aircraft Systems Design and Introduction to Unmanned Aerial Systems, Introduction to UAV Systems is an indispensable resource for anyone seeking coverage of the latest industry advances and technologies in UAV and UAS technology.
The Essential Psychology Series bridges the gap between simple introductory texts aimed at pre-university students and higher level textbooks for upper level undergraduates. Each volume in the series is designed to provide concise yet up-to-date descriptions of the major areas of psychology for first year undergraduates or students taking psychology as a supplement to other courses of study. The authors, who are acknowledged experts in their field, explain the basics carefully and engagingly without the over-simplification often found in introductory textbooks, at the same time providing the reader with insights into current thinking. Essential Biological Psychology is an accessible, well-illustrated and well-written account of the study of the role of the body in behaviour and the effect of behaviour on the working of the body. Covering all the major topics within biopsychology, and evaluating the most up-to-date findings, particularly within neuroscience and neuroimaging research, this textbook is essential reading for first and second level undergraduates taking courses in biological or physiological psychology as well as anyone studying courses in neuropsychology or behavioural neuroscience.
Spectral techniques facilitate the design and testing of today's increasingly complex digital devices There is heightened interest in spectral techniques for the design of digital devices dictated by ever increasing demands on technology that often cannot be met by classical approaches. Spectral methods provide a uniform and consistent theoretic environment for recent achievements in this area, which appear divergent in many other approaches. Spectral Logic and Its Applications for the Design of Digital Devices gives readers a foundation for further exploration of abstract harmonic analysis over finite groups in the analysis, design, and testing of digital devices. After an introduction, this book provides the essential mathematical background for discussing spectral methods. It then delves into spectral logic and its applications, covering: * Walsh, Haar, arithmetic transform, Reed-Muller transform for binary-valued functions and Vilenkin-Chrestenson transform, generalized Haar, and other related transforms for multiple-valued functions * Polynomial expressions and decision diagram representations for switching and multiple-value functions * Spectral analysis of Boolean functions * Spectral synthesis and optimization of combinational and sequential devices * Spectral methods in analysis and synthesis of reliable devices * Spectral techniques for testing computer hardware This is the authoritative reference for computer science and engineering professionals and researchers with an interest in spectral methods of representing discrete functions and related applications in the design and testing of digital devices. It is also an excellent text for graduate students in courses covering spectral logic and its applications.
Adhesives and Finishes for Wood Understand the science of joining wood with this comprehensive guide Long seen as an old-fashioned material with narrowing modern applications, wood has seen increased popularity as a material in building and manufacturing in recent years. This has been driven by the need for sustainable resources and environmentally friendly materials. As a result of increased emphasis on wood, however, there is a corresponding need to understand the wood adhesives, the crucial materials in wood-based manufacture and craftsmanship. Adhesives and Finishes for Wood meets this need with a comprehensive but accessible introduction to the chemistry and applications of wood adhesives. Its easy-to-follow presentation nonetheless presents wood adhesives and finishes in significant detail. Ideal for readers without considerable preexisting knowledge in chemistry, this book includes everything the reader needs to understand and apply wood adhesives in their work or industry. Adhesives and Finishes for Wood readers will also find: Coverage ranging from the fundamentals of wood adhesive polymer chemistry to the properties of specific wood structures and resins A presentation suitable for both academic students and wood manufacture professionals An author with decades of experience in both academia and industry Adhesives and Finishes for Wood is a useful reference for advanced students and professionals in industries or manufacturing disciplines that incorporate wood, as well as for chemists, materials scientists, vocational school instructors, and more.
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