This book provides a comprehensive overview of the field of aerosol science related to particle inhalation and its effect on the lung, predominately in humans. It covers the basics of aerosol behavior, transport, deposition, clearance, and effects of aerosols, both environmental and therapeutic. Aimed at the researcher entering the field of aerosol inhalation it provides a valuable introductory resource in an accessible format.
The lung receives the entire cardiac output from the right heart and must load oxygen onto and unload carbon dioxide from perfusing blood in the correct amounts to meet the metabolic needs of the body. It does so through the process of passive diffusion. Effective diffusion is accomplished by intricate parallel structures of airways and blood vessels designed to bring ventilation and perfusion together in an appropriate ratio in the same place and at the same time. Gas exchange is determined by the ventilation-perfusion ratio in each of the gas exchange units of the lung. In the normal lung ventilation and perfusion are well matched, and the ventilation-perfusion ratio is remarkably uniform among lung units, such that the partial pressure of oxygen in the blood leaving the pulmonary capillaries is less than 10 Torr lower than that in the alveolar space. In disease, the disruption to ventilation-perfusion matching and to diffusional transport may result in inefficient gas exchange and arterial hypoxemia. This volume covers the basics of pulmonary gas exchange, providing a central understanding of the processes involved, the interactions between the components upon which gas exchange depends, and basic equations of the process.
New insights for understanding and combating Al Qaeda and other contemporary security threats Wars were once fought mainly between nations—a presumption put to rest on September 11, 2001. Al Qaeda showed that nonstate actors could threaten a traditional nation-state and pursue strategic objectives without conventional weaponry, thereby altering the nature of war and often rendering military firepower meaningless. National security expert Max G. Manwaring examines the emergence of nonstate actors in a geopolitical world. Manwaring invites policy makers to look past familiar insurgencies such as those in Vietnam and Iraq and consider global security problems from multiple perspectives. He concludes that the use of calculated political and psychological power may be the most effective response in many situations. The power to make war no longer rests solely in the hands of traditional governments. Manwaring analyzes the context, conduct, and outcome of today’s irregular wars and applies proven methods of effective response to seven case studies: Colombia, Al Qaeda, Portugal, Uruguay, Venezuela, Italy, and Central American gangs and criminal organizations. Insurgency, Terrorism, and Crime translates the cogent lessons of recent events into workable strategies for tomorrow’s leaders. This book is required reading for students of national security policy and foreign-policy analysis.
This book provides a comprehensive overview of the field of aerosol science related to particle inhalation and its effect on the lung, predominately in humans. It covers the basics of aerosol behavior, transport, deposition, clearance, and effects of aerosols, both environmental and therapeutic. Aimed at the researcher entering the field of aerosol inhalation it provides a valuable introductory resource in an accessible format.
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