This book offers an overall review, applying systems engineering and architecture approaches, of the design, optimization, operation and results of leading fusion experiments. These approaches provide a unified means of evaluating reactor design. Methodologies are developed for more coherent construction or evaluation of fusion devices, associated experiments and operating procedures. The main focus is on tokamaks, with almost all machines and their important results being integrated into a systems design space. Case studies focus on DIII-D, TCV, JET, WEST, the fusion reactor prototype ITER and the EU DEMO concept. Stellarator, Mirror and Laser inertial confinement experiments are similarly analysed, including reactor implications of breakeven at NIF. The book examines the engineering and physics design and optimization process for each machine, analysing their performance and major results achieved, thus establishing a basis for the improvement of future machines. The reader will gain a broad historical and up-to-date perspective of the status of nuclear fusion research from both an engineering and physics point of view. Explanations are given of the computational tools needed to design and operate successful experiments and reactor-relevant machines. This book is aimed at both graduate students and practitioners of nuclear fusion science and engineering, as well as those specializing in other fields demanding large and integrated experimental equipment. Systems engineers will obtain valuable insights into fusion applications. References are given to associated complex mathematical derivations, which are beyond the scope of this book. The general reader interested in nuclear fusion will find here an accessible summary of the current state of nuclear fusion.
The second edition of this bestselling title provides the most up-to-date comprehensive review of all aspects of biomaterials science by providing a balanced, insightful approach to learning biomaterials. This reference integrates a historical perspective of materials engineering principles with biological interactions of biomaterials. Also provided within are regulatory and ethical issues in addition to future directions of the field, and a state-of-the-art update of medical and biotechnological applications. All aspects of biomaterials science are thoroughly addressed, from tissue engineering to cochlear prostheses and drug delivery systems. Over 80 contributors from academia, government and industry detail the principles of cell biology, immunology, and pathology. Focus within pertains to the clinical uses of biomaterials as components in implants, devices, and artificial organs. This reference also touches upon their uses in biotechnology as well as the characterization of the physical, chemical, biochemical and surface properties of these materials. - Provides comprehensive coverage of principles and applications of all classes of biomaterials - Integrates concepts of biomaterials science and biological interactions with clinical science and societal issues including law, regulation, and ethics - Discusses successes and failures of biomaterials applications in clinical medicine and the future directions of the field - Cover the broad spectrum of biomaterial compositions including polymers, metals, ceramics, glasses, carbons, natural materials, and composites - Endorsed by the Society for Biomaterials
Collaborative research in bioinformatics and systems biology is a key element of modern biology and health research. This book highlights and provides access to many of the methods, environments, results and resources involved, including integral laboratory data generation and experimentation and clinical activities. Collaborative projects embody a research paradigm that connects many of the top scientists, institutions, their resources and research worldwide, resulting in first-class contributions to bioinformatics and systems biology. Central themes include describing processes and results in collaborative research projects using computational biology and providing a guide for researchers to access them. The book is also a practical guide on how science is managed. It shows how collaborative researchers are putting results together in a way accessible to the entire biomedical community.
This book offers an overall review, applying systems engineering and architecture approaches, of the design, optimization, operation and results of leading fusion experiments. These approaches provide a unified means of evaluating reactor design. Methodologies are developed for more coherent construction or evaluation of fusion devices, associated experiments and operating procedures. The main focus is on tokamaks, with almost all machines and their important results being integrated into a systems design space. Case studies focus on DIII-D, TCV, JET, WEST, the fusion reactor prototype ITER and the EU DEMO concept. Stellarator, Mirror and Laser inertial confinement experiments are similarly analysed, including reactor implications of breakeven at NIF. The book examines the engineering and physics design and optimization process for each machine, analysing their performance and major results achieved, thus establishing a basis for the improvement of future machines. The reader will gain a broad historical and up-to-date perspective of the status of nuclear fusion research from both an engineering and physics point of view. Explanations are given of the computational tools needed to design and operate successful experiments and reactor-relevant machines. This book is aimed at both graduate students and practitioners of nuclear fusion science and engineering, as well as those specializing in other fields demanding large and integrated experimental equipment. Systems engineers will obtain valuable insights into fusion applications. References are given to associated complex mathematical derivations, which are beyond the scope of this book. The general reader interested in nuclear fusion will find here an accessible summary of the current state of nuclear fusion.
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