Anger is a natural human emotion that can serve important survival functions, but the excessive presence of anger and its associated negative outcomes—such as aggression and violence—can lead to significant interpersonal, intrapersonal, occupational, legal, familial, societal, and physical health problems. Unfortunately, clinical anger clients haven’t historically been helped in truly sustainable ways, and loved ones and society at large are often left to simply watch as these individuals struggle to overcome their anger and the noxious behaviors that often emanate from this troubling condition. Contextual Anger Regulation Therapy gives clinicians the power to change this. The book presents an exciting nine-module mindfulness and acceptance-based behavioral treatment program that has been effectively utilized in formal clinical settings with clinical anger clients, including those mandated for treatment following both non-domestic and domestic violence. Treatment success has not only been demonstrated in observable ways, including significant reductions in violence recidivism and marked improvements in quality of life; it has also been seen in scientific data both in the laboratory and with large numbers of mandated clinical anger clients.
The MAC approach developed by connecting the more traditional scientific knowledge base on human performance and self-regulation to more contemporary findings to do with meta-cognitive processes, emotion regulation, and acceptance-based behavioral interventions. Written by the originators of the MAC model, this book will provide both the necessary theory, empirical background, and a structured step-by-step, easy-to-use protocol for the understanding, assessment, conceptualization, and enhancement of human performance. It is a protocol that can be readily adapted for a wide variety of high-performing clientele--from athletes and business people, to sales people, professionals in a variety of fields, and emergency/military personnel. The material can be integrated by practicing clinicians as an adjunctive intervention strategy to help clients with specific performance problems. Numerous case examples, forms, handouts, in- and out-of-session assignments and activities, and verbatim client instructions are included.
In this provocative study the author challenges many contemporary assumptions about the modern family, the circumstances of home life which lead to academic success and the proper relationship between home and school. The modern family is not 'in decline'; its history is a success story. It is stable, unsociable, emotionally potent. Over the past three centuries it has turned its back on society. It is less remarkable for rebellious children than for the remorseless pressures it can exert upon the young, particularly for 'success' in the school system. In the home-centred society the school is an extension of the home, created in its image. Academic success seems most certain when the 'good home' and the 'good school' form a determined alliance. The combined pressures of home and school often seem to produce withdrawn, self-disparaging and negative young men and women. The author argues that the good school must counter-act many of the influences of the good home and that the educational system must re-order its affairs so that it is able to encourage and assess achievement which comes from joy rather than neurotic drive.
A riveting account of one of the most scandalous unsolved murders at the turn of the nineteenth century: the killing of twenty-four-year-old May Fosburgh. Shots rang out in a prominent Pittsfield family home on the morning of August 20, 1900, ending the life of young socialite May Fosburgh. Who pulled the trigger was unclear, and the scandal captivated attention well beyond the Berkshires. Her brother was a top suspect, but the distraught family claimed an intruder was to blame. Investigators, media and the public struggled to make sense of conflicting details, including suspicious gunpowder residue, as the mystery remained unsolved. Author Frank J. Leskovitz unravels the tale that still lingers in the hills generations later. Includes photos! “A clear, thorough account of this old crime . . . The book respects the dead but also respects the interest readers take in the past.” —Greenfield Recorder
This book addresses the COVID-19 pandemic from a quantitative perspective based on mathematical models and methods largely used in nonlinear physics. It aims to study COVID-19 epidemics in countries and SARS-CoV-2 infections in individuals from the nonlinear physics perspective and to model explicitly COVID-19 data observed in countries and virus load data observed in COVID-19 patients. The first part of this book provides a short technical introduction into amplitude spaces given by eigenvalues, eigenvectors, and amplitudes.In the second part of the book, mathematical models of epidemiology are introduced such as the SIR and SEIR models and applied to describe COVID-19 epidemics in various countries around the world. In the third part of the book, virus dynamics models are considered and applied to infections in COVID-19 patients. This book is written for researchers, modellers, and graduate students in physics and medicine, epidemiology and virology, biology, applied mathematics, and computer sciences. This book identifies the relevant mechanisms behind past COVID-19 outbreaks and in doing so can help efforts to stop future COVID-19 outbreaks and other epidemic outbreaks. Likewise, this book points out the physics underlying SARS-CoV-2 infections in patients and in doing so supports a physics perspective to address human immune reactions to SARS-CoV-2 infections and similar virus infections.
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
The MAC approach developed by connecting the more traditional scientific knowledge base on human performance and self-regulation to more contemporary findings to do with meta-cognitive processes, emotion regulation, and acceptance-based behavioral interventions. Written by the originators of the MAC model, this book will provide both the necessary theory, empirical background, and a structured step-by-step, easy-to-use protocol for the understanding, assessment, conceptualization, and enhancement of human performance. It is a protocol that can be readily adapted for a wide variety of high-performing clientele--from athletes and business people, to sales people, professionals in a variety of fields, and emergency/military personnel. The material can be integrated by practicing clinicians as an adjunctive intervention strategy to help clients with specific performance problems. Numerous case examples, forms, handouts, in- and out-of-session assignments and activities, and verbatim client instructions are included.
In this provocative study the author challenges many contemporary assumptions about the modern family, the circumstances of home life which lead to academic success and the proper relationship between home and school. The modern family is not ‘in decline’; its history is a success story. It is stable, unsociable, emotionally potent. Over the past three centuries it has turned its back on society. It is less remarkable for rebellious children than for the remorseless pressures it can exert upon the young, particularly for ‘success’ in the school system. In the home-centred society the school is an extension of the home, created in its image. Academic success seems most certain when the ‘good home’ and the ‘good school’ form a determined alliance. The combined pressures of home and school often seem to produce withdrawn, self-disparaging and negative young men and women. The author argues that the good school must counter-act many of the influences of the good home and that the educational system must re-order its affairs so that it is able to encourage and assess achievement which comes from joy rather than neurotic drive.
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