Praise for Investment Manager Analysis "This is a book that should have been written years ago. It provides a practical, thorough, and completely objective method to analyze and select an investment manager. It takes the mystery (and the consultants) out of the equation. Without question, this book belongs on every Plan Sponsor's desk." —Dave Davenport, Assistant Treasurer, Lord Corporation, author of The Equity Manager Search "An insightful compendium of the issues that challenge those responsible for hiring and firing investment managers. Frank Travers does a good job of taking complicated analytical tools and methodologies and explaining them in a simple, yet practical manner. Anyone responsible for conducting investment manager due diligence should have a copy on their bookshelf." —Leon G. Cooperman, Chairman and CEO, Omega Advisors, Inc. "Investment Manager Analysis provides a good overview of the important areas that purchasers of institutional investment management services need to consider. It is a good instructional guide, from which search policies and procedures can be developed, as well as a handy reference guide." —David Spaulding, President, The Spaulding Group, Inc. "This book is the definitive work on the investment manager selection process. It is comprehensive in scope and well organized for both the layman and the professional. It should be required reading for any organization or individual seeking talent to manage their assets." —Scott Johnston, Chairman and Chief Investment Officer, Sterling Johnston Capital Management, LP "Investment Manager Analysis is a much-needed, comprehensive review of the manager selection process. While the industry is riddled with information about selecting individual stocks, comparatively little has been written on the important subject of manager selection for fund sponsors. This is a particularly useful guide for the less experienced practitioner and offers considerable value to the veteran decisionmaker as well." —Dennis J. Trittin, CFA, Portfolio Manager, Russell Investment Group
A detailed, step-by-step book covering the entire hedge fund evaluation process Investing in hedge funds is different from investing in other asset classes. There is much less publicly available information about hedge funds performance than there is about mutual funds or individual stocks. Consequently, investing in this class requires more sophisticated investment knowledge, greater due diligence, and, in many cases, a better-developed ability to evaluate investment managers. Hedge Fund Analysis provides a broad framework of how to approach this endeavor, from initial screening to analytical techniques, interviewing skills, and legal and contract negotiations. Along the way, it demonstrates a variety of mechanisms for monitoring and tracking hedge funds and the underlying hedge fund portfolios—explaining each stage of the process in minute detail and providing specific examples which fully explain the opportunities and challenges you'll face each step of the way. Provides a detailed look at how to source hedge funds, screen through them, and rank their strengths and weaknesses Lays out a thorough process for evaluating funds, from initial interviews to performance analysis to onsite meetings Reveals what questions to ask by strategy in order to understand the underlying risk factors associated with each Highlights non-investment analysis, including operational due diligence and risk management, as integral elements in the process Written by a financial professional with over twenty years of experience conducting investment manager due diligence, this book will put you in a position to make more informed decisions when investing in hedge funds.
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
The only text to cover the full range of adult cardiac, thoracic, and pediatric chest surgery, Sabiston and Spencer Surgery of the Chest provides unparalleled guidance in a single, two-volume resource. This gold standard reference, edited by Drs. Frank Sellke, Pedro del Nido, and Scott Swanson, covers today's most important knowledge and techniques in cardiac and thoracic surgery—the information you need for specialty board review and for day-to-day surgical practice. Meticulously organized so that you can quickly find expert information on open and endoscopic surgical techniques, this 10th Edition is an essential resource not only for all cardiothoracic surgeons, but also for physicians, residents, and students concerned with diseases of the chest. - Features short, focused chapters divided into three major sections: Adult Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery. - Presents the knowledge and expertise of global experts who provide a comprehensive view of the entire specialty. - Provides full-color coverage throughout, helping you visualize challenging surgical techniques and procedures and navigate the text efficiently. - Includes new chapters on dissection complications and percutaneous treatment of mitral and tricuspid valve disease. - Offers extensively revised or rewritten chapters on surgical revascularization, acute dissection, vascular physiology, the latest innovations in minimally invasive cardiothoracic surgery and percutaneous devices, the molecular biology of thoracic malignancy, robotics in chest surgery, congenital valve reconstructions, novel hybrid procedures in pediatric cardiac surgery, and 3D visualization of cardiac anatomy for surgical procedure planning. - Keeps you up to date with the latest developments in cardiothoracic imaging and diagnosis. - Provides access to more than 30 surgical videos online, and features new figures, tables, and illustrations throughout. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
This book explores the paradox of the ‘security dilemma’ in International Relations, as applied to the post-9/11 context of homeland security. The book's central argument can be summed up by the following counterintuitive thesis: the more security you have, the more security you will need. It argues that enhancing security does not make terrorism more likely, but rather it raises public expectations and amplifies public outrage after subsequent failures. The book contests that this dilemma will continue to shape American, Canadian and British domestic and international security priorities for decades. In exploring the key policy implications resulting from this, the book highlights the difficulty in finding a solution to this paradox, as the most rational and logical policy options are part of the problem. This book will be of interest to students of Homeland Security, Security Studies, US politics, and IR in general.
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