This compact open access reference delves beyond popular concepts of educated consumers and an informed public by examining the science behind deliberative engagement. Using data from four longitudinal studies, the authors assess public engagement methods in deliberative discussions of ethical, legal, and social issues concerning innovations in nanotechnology. Coverage includes the theoretical origins of the studies, forms of engagement and variations used, and in-depth details on cognitive, affective, and social components that go into the critical thinking process and forming of opinions. Not only are the findings intriguing in and of themselves, but researchers from varied fields will also find them useful in pursuing their own projects. Featured in the coverage: Experimental methods and measures used in relation to specific outcomes. Forms of deliberative engagement affecting objective and subjective knowledge. Effects of engagement variables on attitude formation, change, and polarization. Tracing the processes leading to policy acceptance and support. Study conclusions and evaluation. Plus supplemental materials giving readers access to full study data. Since public engagement methods are widely regarded as valuable for policy input, planning purposes, and understanding societal processes, Deliberative Engagement with Science stands to have a wide audience among psychologists, researchers, academics, and policymakers, as well as professionals in the corporate sphere and the tech industries.
Jorge Manrique was the greatest poet of fifteenth-century Castile and one of the three or four greatest in Spanish literature. Frank A. Domínguez offers here an introduction to Manrique's poetry and the first book-length study of him in English in fifty years. After presenting the biographical and historical context of Manrique's poetry, Domínguez examines the poet's love lyrics, describing the large fund of commonplaces and forms that Manrique's verses share with those of other poets of his age. Manrique's highly stylized language and parallel verse structures express the obsession of the lover with the beloved. Moreover, his attention to parallel construe the world's greatest. In treating the Coplas, Domínguez not only offers a sensitive reading of the elegy but also examines questions of text, structure, and style. Like the love lyrics, the Coplas present a high incidence of parallel structures that make for clarity and symmetry. Domínguez also finds that the complex stylistic relationships of the verses provide the Coplas with a unity that is deeper and more fundamental than has generally been perceived. This study, eclectic in its critical approaches, will be the standard English work on Manrique for years to come.
Practical and highly organized, The 5-Minute Clinical Consult 2021 is a reliable, go-to resource for primary care physicians, nurse practitioners, and physician assistants. This bestselling title provides rapid access to guidance on diagnosis, treatment, medications, follow-up, and associated factors for more than 540 diseases and conditions. The 5-Minute Clinical Consult 2021 delivers clinical confidence efficiently, allowing you to focus your valuable time on giving your patients the best possible care. Written by esteemed internal medicine and family medicine practitioners and published by the leading publisher in medical content, The 5-Minute Clinical Consult 2021, 29th Edition is your best resource for patient care.
As we approach the end of the 20th century we can look back upon the achievements that have been made in a variety of human endeavours with pride. Enormous strides have been made to improve the quality of life of millions of people through the application of the scientific discoveries made during this and past centuries. The 20th century will be remembered as much for the mass exploitation of scientific discovery as for the discoveries themselves. The technological age has meant that the human being is able to contemplate activities which "defy" nature. For example, some of the work involved in the preparation of these proceedings has been done whilst travelling at over 500 miles per hour seven miles above the surface of the earth. It is not difficult to conjecture about the effect that this relatively recent technology has had upon a number of "systems". Air transportation has provided a number of benefits including such disparate examples such as enabling holidays, famine relief and the cross fertilisation of cultural practices from other lands. Equally, there have been undesirable effects such as enabling the means of mass destruction, interference in other cultures and the speedy transportation of disease. Moreover, the physical presence of the aeroplane itself represents the consumption of fossil fuels, a source of pollution and a change in the way think about life. The view expressed here is of course the view of an inhabitant of the "western world".
This volume provides individual treatments of the major molluscan taxa. Each chapter provides an overview of the evolution, phylogeny and classification of a group of molluscs, as well as more specific and detailed coverage of their biology (reproduction, feeding and digestion, excretion, respiration etc.), their long fossil record and aspects of their natural history. The book is illustrated with hundreds of colour figures. In both volumes, concepts are summarised in colour-coded illustrations. Key selling features: Comprehensively reviews molluscan biology and evolutionary history Includes a description the anatomy and physiology of anatomical systems Up to date treatment with a comprehensive bibliography Reviews the phylogenetic history of the major molluscan lineages
23 Roots: The History Behind The First 23 Pairs of Air Jordan Sneakers takes you on a ride through the first 23 years of Air Jordan sneakers. This book digs deep into the roots of the Air Jordan brand and brings you the inspiration behind each design, as well as a list of the sneakers that were originally released with images, original release year and original retail price. 23 Roots is sure to take you down memory lane, and revisit the feeling and story behind how you finally acquired that specific pair of prized kicks. Whether you've just gained a passion for Air Jordan sneakers or are a veteran collector with closets full of sneaker boxes, 23 Roots is a must have book for ALL sneaker enthusiasts.
With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain
No other atlas presents pediatric urologic surgery with such care, attention to detail, and respect for the subject. Revised to include a new co-author and new illustrations, this new edition supplements comprehensive, step-by-step coverage of every procedure with the commentary of leading urologists. Over 60 new procedures present the latest advances in pediatric urologic surgery. Clear writing and detailed illustrations make this atlas ideal for both new and experienced surgeons. Depicts surgery as it is actually performed with beautiful illustrations that illuminate every step in each procedure. Follows a surgeon's approach to technique, providing step-by-step instructions so you understand key anatomy and events during surgery. Includes every procedure you might encounter in clinical practice for comprehensive coverage. Features a new co-author and new commentators-the most important names in urology-for expert guidance and a fresh understanding of the subject. Covers over 60 new procedures, including laparoscopic varicocele ligation, incision of the urethral plate, ileovesicostomy, laparoscopic orchiectomy, and cloacal exstrophy, to help you provide the best outcomes for pediatric patients.
The only text to cover the full range of adult cardiac, thoracic, and pediatric chest surgery, Sabiston and Spencer Surgery of the Chest provides unparalleled guidance in a single, two-volume resource. This gold standard reference, edited by Drs. Frank Sellke, Pedro del Nido, and Scott Swanson, covers today's most important knowledge and techniques in cardiac and thoracic surgery—the information you need for specialty board review and for day-to-day surgical practice. Meticulously organized so that you can quickly find expert information on open and endoscopic surgical techniques, this 10th Edition is an essential resource not only for all cardiothoracic surgeons, but also for physicians, residents, and students concerned with diseases of the chest. - Features short, focused chapters divided into three major sections: Adult Cardiac Surgery, Pediatric Cardiac Surgery, and Thoracic Surgery. - Presents the knowledge and expertise of global experts who provide a comprehensive view of the entire specialty. - Provides full-color coverage throughout, helping you visualize challenging surgical techniques and procedures and navigate the text efficiently. - Includes new chapters on dissection complications and percutaneous treatment of mitral and tricuspid valve disease. - Offers extensively revised or rewritten chapters on surgical revascularization, acute dissection, vascular physiology, the latest innovations in minimally invasive cardiothoracic surgery and percutaneous devices, the molecular biology of thoracic malignancy, robotics in chest surgery, congenital valve reconstructions, novel hybrid procedures in pediatric cardiac surgery, and 3D visualization of cardiac anatomy for surgical procedure planning. - Keeps you up to date with the latest developments in cardiothoracic imaging and diagnosis. - Provides access to more than 30 surgical videos online, and features new figures, tables, and illustrations throughout. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud.
Through seven successful editions, Sabiston & Spencer Surgery of the Chest has set the standard in cardiothoracic surgery references. Now, the new 8th Edition, edited by Frank W. Sellke, MD, Pedro J. del Nido, MD, and Scott J. Swanson, MD, carries on this tradition with updated coverage of today's essential clinical knowledge from leaders worldwide. Guidance divided into three major sections—Adult Cardiac Surgery, Congenital Heart Surgery, and Thoracic Surgery—lets you quickly find what you need, while new and revised chapters reflect all of the important changes within this rapidly evolving specialty. Expert Consult functionality—new to this edition—enables you to access the complete contents of the 2-volume set from anyplace with an Internet connection for convenient consultation where and when you need it. This is an ideal source for mastering all of the most important current knowledge and techniques in cardiac and thoracic surgery—whether for specialty board review or day-to-day practice. Features short, focused chapters that help you find exactly what you need. Presents the work of international contributors who offer a global view of the entire specialty. Covers thoracic surgery as well as adult and pediatric cardiac surgery for a practical and powerful single source. Includes nearly 1,100 illustrations that help to clarify key concepts. Features online access to the complete contents of the 2-volume text at expertconsult.com for convenient anytime, anywhere reference. Covers the hottest topics shaping today's practice, including the latest theory and surgical techniques for mitral valve disease, advances in the treatment of congenital heart disease, minimally invasive surgical approaches to the treatment of adult and congenital cardiac disease and thoracic disease, stent grafting for aortic disease, and cell-based therapies. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
A wide-ranging study that illuminates the connection between epidemic diseases and societal change, from the Black Death to Ebola This sweeping exploration of the impact of epidemic diseases looks at how mass infectious outbreaks have shaped society, from the Black Death to today. In a clear and accessible style, Frank M. Snowden reveals the ways that diseases have not only influenced medical science and public health, but also transformed the arts, religion, intellectual history, and warfare. A multidisciplinary and comparative investigation of the medical and social history of the major epidemics, this volume touches on themes such as the evolution of medical therapy, plague literature, poverty, the environment, and mass hysteria. In addition to providing historical perspective on diseases such as smallpox, cholera, and tuberculosis, Snowden examines the fallout from recent epidemics such as HIV/AIDS, SARS, and Ebola and the question of the world’s preparedness for the next generation of diseases.
Arthritis is an inflammatory disease affecting the joints and surrounding tissues. As the disease develops it can cause severe pain and disability. The two most common types of arthritis are osteoarthritis and rheumatoid arthritis. Osteoarthritis (OA) is a painful, degenerative joint disease that often involves the hips, knees, neck, lower back, or the small joints of the hands. Treatment usually includes analgesics, topical creams, or non-steroidal anti-inflammatory medications (known as NSAIDs); appropriate exercises or physical therapy; joint splinting; or joint replacement surgery for seriously damaged larger joints, such as the knee or hip. Rheumatoid arthritis (RA) is an autoimmune inflammatory disease that usually involves the hands, wrists, elbows, shoulders, knees, feet, or ankles. Focus on Arthritis Research brings together leading research in the field.
The Eye in History is a comprehensive manual describing the structure and function of the eye, ocular disorders and their treatment. Beginning with an introduction to anatomy and discussion on different disorders, the authors also review eye diseases of famous historical people and perception differences between men and women. The final sections discuss eye surgery and future technologies including the bionic eye, nanotechnology and gene therapy. Edited by Frank Joseph Goes of the Goes Eye Centre in Belgium, this multi-authored book has contributions from specialists throughout Europe, as well as the USA. 830 full colour images and illustrations assist comprehension. Key points Comprehensive guide to structure and function of the eye, ocular disorders and treatment Includes sections on eye diseases of famous historical people, the art of painting and perception Discusses future technologies including bionic eye, nanotechnology and gene therapy Edited by Frank Joseph Goes of Goes Eye Centre, Belgium, with contributions from authors across Europe and the USA Features 830 full colour images and illustrations
Teacher leadership is a transformative process that can drive school and community reform. This revised edition of the groundbreaking bestseller builds on current research to help teachers and administrators work together to foster, develop, and support teacher leadership. Principals and staff developers will learn how collaborating with teacher leaders can result in significantly improved school outcomes. With the Teachers as Leaders Framework, teachers can become leaders who facilitate communities of learning, strive for pedagogical excellence, confront barriers in the school's culture and structures, and nurture a culture of success. Featured in the second edition are: five new school case studies with insights about the complexity of teacher leadership, expanded discussion of the capacity-building process for teacher leaders and principals, an outline of a school development program based on teacher leadership and parallel leadership, with exercises for systematically developing teacher leaders, the second edition of this invaluable guide is for every educator who believes in teacher leadership as a crucial step toward making schools a source of instruction and inspiration."--PUBLISHER'S WEBSITE.
Cryo-EM, as it is currently practiced in many laboratories, is limited to the visualization of molecules that are in thermal equilibrium at the time before freezing. A further limitation is that the existing software does not fully exploit the information that is contained in the images of large ensembles of molecules in thermal equilibrium. This book is a collection of recent articles by the author, reprinted with introductions, and they mainly describe two novel methods in cryo-EM, one computational and the other experimental that requires the use of a microfluidic device. Both methods have the capacity to shed light on the dynamic behavior of biomolecules. Combined, they greatly expand the range of applications of cryo-EM. The book describes a successful approach in which, based on cryo-EM data, all states visited by the molecule in thermal equilibrium are mapped by manifold embedding—a method of geometric machine learning—and the energy landscape of the molecule is derived. It also discusses methods and biological results of time-resolved cryo-EM, following a reaction in a non-equilibrium system over a short period of time and resulting in the capture of short-lived states that have been inaccessible by standard methods of cryo-EM.
Use your knowledge of pharmacology to enhance oral care! Pharmacology and Therapeutics for Dentistry, 6th Edition describes how to evaluate a patient's health and optimize dental treatment by factoring in the drugs they take. It explores the basic fundamentals of pharmacology, special topics such as pain control, fear and anxiety, and oral complications of cancer therapy, and most importantly, the actions of specific drug groups on the human body. Whether you're concerned about the drugs a patient is already taking or the drugs you prescribe for treatment, this book helps you reduce risk and provide effective dental care. - An emphasis on the dental applications of pharmacology relates drugs to dental considerations in clinical practice. - Dental aspects of many drug classes are expanded to include antibiotics, analgesics, and anesthetics. - The Alternative Medicine in Dentistry chapter discusses chemicals used as alternative medicines and assesses their potential benefits and risks. - The Nonopioid Analgesics chapter groups together non-opioid analgesics, nonsterioidal anti-inflammatory drugs, and antirheumatic and antigout drugs, making these easier to locate and study. - Coverage of the endocrine system includes four separate chapters for the most comprehensive coverage. - Drug Interactions in Clinical Dentistry appendix lists potential interactions between drugs a patient is taking for nondental conditions and drugs that may be used or prescribed during dental treatment, including effects and recommendations. - Glossary of Abbreviations appendix includes the most common abbreviations used for drugs or conditions. - New Pharmacogenetics and Pharmacogenomics chapter covers the effects of genetic traits of patients on their responses to drugs. - A NEW introductory section offers tips for the study of dental pharmacology and relates pharmacology to dental considerations. - An updated discussion of drug-drug interactions covers the harmful effects of mixing medications. - Coverage of adverse effects and mechanisms of COX-2 inhibitors, antibiotic prophylaxis, and antiplaque agents explains the dental risks relating to common drug treatments.
The 5-Minute Clinical Consult Standard 2016, 24th Edition, provides rapid-access in a quick-reference print format. It delivers diagnosis, treatment, medications, follow-up, and associated factors for a broad range of diseases and conditions. Organized alphabetically by diagnosis, this best-selling clinical reference continues to present brief, bulleted information on disease topics in a consistent and reader-friendly three-column format. The 5-Minute Clinical Consult Standard 2016, 24th Edition provides: 650+ commonly encountered diseases and disorders 150+ Treatment and diagnostic algorithms ICD10 Codes Current evidence-based designations highlighted in each topic A revised and updated Health Maintenance section The Health Maintenance 1-page summaries, based on the US Preventive Services Task Force recommendations
Long gone are the times when investors could make decisions based on intuition. Modern asset management draws on a wide-range of fields beyond financial theory: economics, financial accounting, econometrics/statistics, management science, operations research (optimization and Monte Carlo simulation), and more recently, data science (Big Data, machine learning, and artificial intelligence). The challenge in writing an institutional asset management book is that when tools from these different fields are applied in an investment strategy or an analytical framework for valuing securities, it is assumed that the reader is familiar with the fundamentals of these fields. Attempting to explain strategies and analytical concepts while also providing a primer on the tools from other fields is not the most effective way of describing the asset management process. Moreover, while an increasing number of investment models have been proposed in the asset management literature, there are challenges and issues in implementing these models. This book provides a description of the tools used in asset management as well as a more in-depth explanation of specialized topics and issues covered in the companion book, Fundamentals of Institutional Asset Management. The topics covered include the asset management business and its challenges, the basics of financial accounting, securitization technology, analytical tools (financial econometrics, Monte Carlo simulation, optimization models, and machine learning), alternative risk measures for asset allocation, securities finance, implementing quantitative research, quantitative equity strategies, transaction costs, multifactor models applied to equity and bond portfolio management, and backtesting methodologies. This pedagogic approach exposes the reader to the set of interdisciplinary tools that modern asset managers require in order to extract profits from data and processes.
Molluscs comprise the second largest phylum of animals (after arthropods), occurring in virtually all habitats. Some are commercially important, a few are pests and some carry diseases, while many non-marine molluscs are threatened by human impacts which have resulted in more extinctions than all tetrapod vertebrates combined. This book and its companion volume provide the first comprehensive account of the Mollusca in decades. Illustrated with hundreds of colour figures, it reviews molluscan biology, genomics, anatomy, physiology, fossil history, phylogeny and classification. This volume includes general chapters drawn from extensive and diverse literature on the anatomy and physiology of their structure, movement, reproduction, feeding, digestion, excretion, respiration, nervous system and sense organs. Other chapters review the natural history (including ecology) of molluscs, their interactions with humans, and assess research on the group. Key features of both volumes: up to date treatment with an extensive bibliography; thoroughly examines the current understanding of molluscan anatomy, physiology and development; reviews fossil history and phylogenetics; overviews ecology and economic values; and summarises research activity and suggests future directions for investigation. Winston F Ponder was a Principal Research Scientist at The Australian Museum in Sydney where he is currently a Research Fellow. He has published extensively over the last 55 years on the systematics, evolution, biology and conservation of marine and freshwater molluscs, as well as supervised post graduate students and run university courses. David R. Lindberg is former Chair of the Department of Integrative Biology, Director of the Museum of Paleontology, and Chair of the Berkeley Natural History Museums, all at the University of California. He has conducted research on the evolutionary history of marine organisms and their habitats on the rocky shores of the Pacific Rim for more than 40 years. The numerous elegant and interpretive illustrations were produced by Juliet Ponder.
Make the most effective diagnostic and therapeutic decisions in the least time! A best seller for over 25 years, The5-Minute Clinical Consult 2018 is a practical and useful resource for clinicians in primary care, family medicine, emergency medicine, nursing, and pediatrics. It provides rapid access to guidance on diagnosis, treatment, medications, follow-up, and associated factors for more than 540 diseases and conditions. The5-Minute Clinical Consult 2018 is designed to deliver maximum clinical confidence as efficiently as possible...allowing you to focus your valuable time on giving your patients the best possible care. Find the answers you need quickly thanks to an intuitive, at-a-glance format, with concise, bulleted text; hundreds of diagnostic and therapeutic algorithms; ICD-10 codes, DSM-5 criteria; and much more. Make confident decisions aided by current evidence-based designations in each topic. Written by esteemed internal medicine and family medicine practitioners and published by the leading publisher in medical content, The 5-Minute Clinical Consult 2018, 26th Edition includes a Free Trial to 5MinuteConsult.com.
The most authoritative guide to sonography in obstetrics and gynecology—now in full color Companion website includes images, case studies, and more Written by radiologists and ob/gyns to provide a balanced perspective, this standard-setting guide is both a clinically relevant reference text and atlas—presented in full color for the first time. It expertly examines the full spectrum of disorders and conditions you’re likely to encounter in gynecologic and maternal-fetal care, supported throughout by more than 2,000 detailed sonographic illustrations. You’ll also find the latest procedures and diagnostic guidelines for the use of sonography in ob/gyn, including 3D and 4D image processing, transvaginal sonography, and color Dopler sonography. The book opens with general obstetric sonography, covering such pivotal topics as normal pelvic anatomy and fetal echocardiography, before moving into fetal anomalies and disorders. Risk assessment and therapy, including first trimester screening and amniocentesis, are explored in the next section, while the remaining parts of the book focus on maternal disorders, gynecological sonography, and the newest complementary imaging modalities. Features The most trusted, accessible compendium of sonography in obstetrics and gynecology for residents and practitioners, filled with precise illustrations that add clarity to the text’s content All-inclusive coverage of everything from sonographic operating instruments and screening the fetal patient for syndromes and anomalies, to diagnosing the female patient for cysts, infertility, and incontinence NEW! Full-color format to aid readability and ease of use NEW! Up-to-date information on the significant advances made in three dimensional and even four-dimensional Doppler technology NEW! Learning aids: a “key points” section in each chapter; skill-building clinical scenarios; a stronger focus on differential diagnosis; multiple visuals (figure, illustration, or table) on each page; and helpful chapter-opening summaries NEW! Companion website filled with concept-clarifying images, video loops, case studies supplemented by Q&As, plus cutting-edge insights on a range of integral sonography topics NEW! SI Units incorporated throughout
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