Frank F. Scherer's Books

The Freudian Orient

Early Psychoanalysis, Anti-Semitic Challenge, and the Vicissitudes of Orientalist Discourse

By: Frank F. Scherer

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The Freudian Orient

Early Psychoanalysis, Anti-Semitic Challenge, and the Vicissitudes of Orientalist Discourse

By: Frank F. Scherer

This study consists of a twofold, interrelated enquiry: the Orientalism of psychoanalysis and the psychoanalysis of Orientalism - bringing into conversation Sigmund Freud and Edward Said and, thereby, the founding texts of psychoanalysis and postcolonial studies. The immediate object of this exploration is the "Freudian Orient" and we thus begin by tracing the strong Orientalist presence in Freud's writings with examples from his early as well as later correspondence, his diaries, and his psychological works. Following these examples of "manifest" Orientalism, we will pursue more "latent" meanings by engaging two of Freud's favorite metaphors: archaeology and travel. Whereas the former soon uncovers a veritable porta Orientis, conducting to an external Orient, the latter reveals an internalised Orient traversed by Jewishness, anti-Semitism and the Bible. Unveiling the figure of Moses shows how Freud's strategy to resist anti-Semitic Orientalism by way of universalist reversal is only partially successful as he cannot extricate himself from the historical assumptions of that discourse.

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Page Count

248

Publisher

Routledge

Published Date

ISBN 10

0429920849

ISBN 13

9780429920844

ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins

Applications in Drug Discovery and Development

By: Honghui Zhou,Frank-Peter Theil

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ADME and Translational Pharmacokinetics / Pharmacodynamics of Therapeutic Proteins

Applications in Drug Discovery and Development

By: Honghui Zhou,Frank-Peter Theil

With an emphasis on the fundamental and practical aspects of ADME for therapeutic proteins, this book helps readers strategize, plan and implement translational research for biologic drugs. • Details cutting-edge ADME (absorption, distribution, metabolism and excretion) and PKPD (pharmacokinetic / pharmacodynamics) modeling for biologic drugs • Combines theoretical with practical aspects of ADME in biologic drug discovery and development and compares innovator biologics with biosimilar biologics and small molecules with biologics, giving a lessons-learned perspective • Includes case studies about leveraging ADME to improve biologics drug development for monoclonal antibodies, fusion proteins, pegylated proteins, ADCs, bispecifics, and vaccines • Presents regulatory expectations and industry perspectives for developing biologic drugs in USA, EU, and Japan • Provides mechanistic insight into biodistribution and target-driven pharmacokinetics in important sites of action such as tumors and the brain

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