In recent years, developments in ultrasound, computed tomography and magnetic resonance imaging have made important changes in the practice of diagnostic radio logy. Concomitantly, invasive radiology for both diagnostic and therapeutic purposes has grown into a rapidly evolving subspecialty. This text represents a landmark in paediatric radiology. The three authors are distinguished radiologists who, over the past two decades, have greatly contributed to paediatric hepatology. Their pioneering work in the area of splanchnic angiography and diagnostic as well as therapeutic cholangiography was facilitated by their close day-to-day interaction with the Paediatric Liver Disease Unit at Höpital Bicetre. The contents and the format of this "atlas" are testimony to their knowledge of clinical hepatology and to their wide experience in invasive paediatric radiology. The out standing quality of the images is enhanced by appropriate clinical descriptions which will help the reader understand the indications for these procedures, their accuracy and limitations.
Clinical features (progressive psychomotor retardation, seizures, movement disorders and motor signs in both central and peripheral systems, sensorineural defects, and psychiatric symptoms) and brain imaging are the keys to diagnosis. CT is indicated for the detection of calcifications and blood, and for angiography. MRI in all three axes requires T1, T2, FLAIR (from 1 year on), eventually T2* or contrast administration, and diffusion in any acute condition. MR spectroscopy allows the dectection of lactate and creatine deficiency, elevated choline in high membrane turnover, and low NAA in neuronal death. The normal sequence of myelination needs to be taken into account. Pre- and neonatal anomalies include cystic and basal ganglia lesions, gyral and myelin anomalies, callosal agenesis, and large subdural spaces. Anomalies disclosed after 3 months of age include basal ganglia appearing hyper- or hypointense on T2, hypointense on T2*, or calcified white matter anomalies mainly periventricular or subcortical, or with contrast enhancement, associated with macrocephaly and/or large or very small cysts, and hypomyelination; there may be “vascular” or pseudostroke disorders, cortical atrophy, hypoplasia, or abnormal signal of the brainstem and/or cerebellum. Spectroscopy should investigate basal ganglia, white matter, and the cerebellum. MRI may reveal typical alterations of the brain at the preclinical stage in siblings of affected children.
The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. It can stand-alone; together, with Part A: Structure and Mechanisms, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for students and exercise solutions for instructors.
“Cukier and his co-authors have a more ambitious project than Kahneman and Harari. They don’t want to just point out how powerfully we are influenced by our perspectives and prejudices—our frames. They want to show us that these frames are tools, and that we can optimise their use.” —Forbes From pandemics to populism, AI to ISIS, wealth inequity to climate change, humanity faces unprecedented challenges that threaten our very existence. The essential tool that will enable humanity to find the best way foward is defined in Framers by internationally renowned authors Kenneth Cukier, Viktor Mayer-Schönberger, and Francis de Véricourt. To frame is to make a mental model that enables us to make sense of new situations. Frames guide the decisions we make and the results we attain. People have long focused on traits like memory and reasoning, leaving framing all but ignored. But with computers becoming better at some of those cognitive tasks, framing stands out as a critical function—and only humans can do it. This book is the first guide to mastering this human ability. Illustrating their case with compelling examples and the latest research, authors Cukier, Mayer-Schönberger, and de Véricourt examine: · Why advice to “think outside the box” is useless · How Spotify beat Apple by reframing music as an experience · How the #MeToo twitter hashtag reframed the perception of sexual assault · The disaster of framing Covid-19 as equivalent to seasonal flu, and how framing it akin to SARS delivered New Zealand from the pandemic Framers shows how framing is not just a way to improve how we make decisions in the era of algorithms—but why it will be a matter of survival for humanity in a time of societal upheaval and machine prosperity.
For the fourth English edition, this highly popular book has been thoroughly revised and updated to include such new sections as endoscopic digestive US and abnormalities related to AIDS. It is the only work available covering the diagnostic US of the whole abdomen, and its superb treatment of elementary symptoms enables beginners to become familiar with more complicated features. After an extensive technical introduction, the book covers the sonoanatomy and ultrasonic symptomatology of the diseases of the digestive system and the abdominal vessels. Numerous tips on avoiding pitfalls, as well as indications for other procedures, and backed by some 1000 illustrations, this is well on its way to becoming a standard text for practitioners and clinicians in the field.
In For The People James Cameron charts the institutional development of St Francis Xavier University from 1853 to 1970 and illustrates how the college has become an integral part of the region's history and culture through its tradition of service to the people of eastern Nova Scotia on both the mainland and Cape Breton Island.
In recent years, developments in ultrasound, computed tomography and magnetic resonance imaging have made important changes in the practice of diagnostic radio logy. Concomitantly, invasive radiology for both diagnostic and therapeutic purposes has grown into a rapidly evolving subspecialty. This text represents a landmark in paediatric radiology. The three authors are distinguished radiologists who, over the past two decades, have greatly contributed to paediatric hepatology. Their pioneering work in the area of splanchnic angiography and diagnostic as well as therapeutic cholangiography was facilitated by their close day-to-day interaction with the Paediatric Liver Disease Unit at Höpital Bicetre. The contents and the format of this "atlas" are testimony to their knowledge of clinical hepatology and to their wide experience in invasive paediatric radiology. The out standing quality of the images is enhanced by appropriate clinical descriptions which will help the reader understand the indications for these procedures, their accuracy and limitations.
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