This ICME-13 Topical Survey reviews the state-of-the-art by first exploring the roots and scope of design science. Second, it presents two examples of current design science projects that focus on substantial learning environments including a student and a teacher perspective. Subsequently, the book elaborates on how empirical research can be conceptualised within design science. Lastly, it explores developments in design science from a national and international perspective, while also discussing current trends in design research. Within the German-language tradition, considering ‘mathematics education as a design science’ primarily draws on the works of Wittmann. The core of this approach constitutes designing and investigating learning environments that involve substantial mathematics.
Principles of International Criminal Law is one of the leading textbooks in the field. This third edition builds on the highly-successful work of the previous editions, setting out the general principles governing international crimes as well as the fundamentals of both substantive and procedural international criminal law.
This concise dictionary is intended to be helpful in the reading of archaeological books and publications, and in the writing of papers and articles in both English and German.
In Freud’s Adolescence, Florian Houssier looks at the early years of the Father of Psychoanalysis and considers how his personal experiences shaped his later work. Including excerpts from many letters written by Freud himself, this volume allows a rare glimpse into the inner thoughts and emotions of one of his generation’s greatest minds. Engaging with this lesser-known period of Freud’s life, the vivacity of his incestuous and parricidal fantasies comes to the surface, infiltrating his relational life as well as his dreams. Houssier proposes a new hypothesis about the conflicts of Freud’s adolescence, and their impact on his tendencies in later conflicts. This is the first book that sustains a systematic analysis of this material and adds a new dimension to the biography of Freud by exploring links between his life and creativity from a current theorisation of the adolescent process. This book will be an essential read for all psychoanalysts, psychologists, lecturers, followers of Freud’s work and those looking into psychoanalysis as a whole.
What does it mean to be modern? This study regards the concept of ‘society’ as foundational to modern self-understanding. Identifying Arabic conceptualizations of society in the journal al-Manar, the mouthpiece of Islamic reformism, the author shows how modernity was articulated from within an Islamic discursive tradition. The fact that the classical term umma was a principal term used to conceptualize modern society suggests the convergence of discursive traditions in modernity, rather than a mere diffusion of European concepts.
NONTHERMAL PLASMAS FOR MATERIALS PROCESSING This unique book covers the physical and chemical aspects of plasma chemistry with polymers and gives new insights into the interaction of physics and chemistry of nonthermal plasmas and their applications in materials science for physicists and chemists. The properties and characteristics of plasmas, elementary (collision) processes in the gas phase, plasma surface interactions, gas discharge plasmas and technical plasma sources, atmospheric plasmas, plasma diagnostics, polymers and plasmas, plasma polymerization, post-plasma processes, plasma, and wet-chemical processing, plasma-induced generation of functional groups, and the chemical reactions on these groups along with a few exemplary applications are discussed in this comprehensive but condensed state-of-the-art book on plasma chemistry and its dependence on plasma physics. While plasma physics, plasma chemistry, and polymer science are often handled separately, the aim of the authors is to harmoniously join the physics and chemistry of low-pressure and atmospheric-pressure plasmas with polymer surface chemistry and polymerization and to compare such chemistry with classic chemistry. Readers will find in these chapters Interaction of plasma physics and chemistry in plasmas and at the surface of polymers; Explanation and interpretation of physical and chemical mechanisms on plasma polymerization and polymer surface modification; Introduction of modern techniques in plasma diagnostics, surface analysis of solids, and special behavior of polymers on exposure to plasmas; Discussion of the conflict of energy-rich plasma species with permanent energy supply and the much lower binding energies in polymers and alternatives to avoid random polymer decomposition Technical applications such as adhesion, cleaning, wettability, textile modification, coatings, films, etc. New perspectives are explained about how to use selective and mild processes to allow post-plasma chemistry on non-degraded polymer surfaces. Audience Physicists, polymer chemists, materials scientists, industrial engineers in biomedicine, coatings, printing, etc.
The endocannabinoid system represents a highly complex lipid-based (neuro-) transmitter system and can be found in nearly all animals. Since the discovery of the two main cannabinoid receptors CB1 and CB2 in the early '90, intensive research reviled a substantial influence of this system on many physiological and pathophysiological processes. Direct and selective targeting of the system bears a huge potential for the development of novel therapeutic approaches, especially for the treatment of chronical pain, inflammation or other neurological disorders. Therefore, the endocannabinoid system is a promising target in drug development. In the presented thesis, the design, syntheses and pharmacologic evaluation of substituted coumarins as potential new drug candidates as selective synthetic cannabinoids were investigated. In a combinatorial synthetic approach, several new libraries of new ligands were synthesised and subsequently pharmacological tested. Additionally, in a second project, novel reversible monoacylglycerol lipase (MAGL) inhibitors have been synthesized and pharmacologically evaluated. Thereby, several important structure-activity relationships for high potency or selectivity were found. Nearly all potencies of the developed inhibitors were determined in the nanomolar regions.
This ICME-13 Topical Survey reviews the state-of-the-art by first exploring the roots and scope of design science. Second, it presents two examples of current design science projects that focus on substantial learning environments including a student and a teacher perspective. Subsequently, the book elaborates on how empirical research can be conceptualised within design science. Lastly, it explores developments in design science from a national and international perspective, while also discussing current trends in design research. Within the German-language tradition, considering ‘mathematics education as a design science’ primarily draws on the works of Wittmann. The core of this approach constitutes designing and investigating learning environments that involve substantial mathematics.
This ICME-13 Topical Survey reviews the state-of-the-art by first exploring the roots and scope of design science. Second, it presents two examples of current design science projects that focus on substantial learning environments including a student and a teacher perspective. Subsequently, the book elaborates on how empirical research can be conceptualised within design science. Lastly, it explores developments in design science from a national and international perspective, while also discussing current trends in design research. Within the German-language tradition, considering ‘mathematics education as a design science’ primarily draws on the works of Wittmann. The core of this approach constitutes designing and investigating learning environments that involve substantial mathematics.
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