Trichinellosis is a parasitic zoonosis caused by the nematode Trichinella spp. Neurotrichinellosis represents one of the most important complications of severe trichinellosis in humans and is sometimes fatal, especially when Trichinella spiralis is involved. There are numerous mechanisms responsible for the involvement of the nervous system through direct or indirect involvement of the parasite. In the latter, inflammatory cells, especially eosinophils, appear to play a crucial role. Encephalopathy, neuromuscular disturbances, and ocular involvement represent the most frequent presentations of neurotrichinellosis, with the first being the most responsible for fatalities. The diagnosis is based on imaging (CT or MRI), which shows nodular multifocal hypodensities in serologically positive individuals with relevant epidemiological factors (e.g., consumption of raw pork). However, only direct diagnosis by muscle biopsy can give the absolute certainty of infection. Albendazole and mebendazole are the anthelminthic of choice and should be used with corticosteroids to prevent allergic manifestations.
A radical new perspective on the dynamics of urban life in Renaissance Italy The cities of Renaissance Italy comprised a network of forces shaping both the urban landscape and those who inhabited it. In this illuminating study, those complex relations are laid bare and explored through the lens of contemporary urban theory, providing new insights into the various urban centers of Italy’s transition toward modernity. The book underscores how the design and structure of public space during this transformative period were intended to exercise a certain measure of authority over its citizens, citing the impact of architecture and street layout on everyday social practices. The ensuing chapters demonstrate how the character of public space became increasingly determined by the habits of its residents, for whom the streets served as the backdrop of their daily activities. Highlighting major hubs such as Rome, Florence, and Bologna, as well as other lesser-known settings, Street Life in Renaissance Italy offers a new look at this remarkable era.
Weaving together social, political, economic and architectural history, this book explores the role of key patrons in Siena's urban projects, including Pope Pius II Piccolomini and his family, and the quasi-despot Pandolfo Petrucci.
We live in a world in which almost all states purport to be republican. Very few adhere to the Ciceronian concept of res publica, understood as “that which belongs to the popolo (respublica respopuli) [...] and which has the observance of the law and the commonality of interests as its foundation”. The concept of republicanism is traditionally connected to the principle that true political freedom consists of not being subject to the arbitrary will of any man or group of men, and it requires equality of civil and political rights. Republicanism has attracted scholars who aim to develop insights from the classical republican tradition into an attractive political doctrine suitable for modern pluralistic societies. The volume examines republicanism from an historical and theoretical perspective after many years of scholarly investigation and debate.
Un’afosa sera d’estate: un’esplosione sconvolge Asti. L’incendio conseguente distrugge la APES azienda specializzata nello stoccaggio di rifiuti; nella tragedia perdono la vita due dipendenti. Contemporaneamente in un incidente avvenuto poco distante dal luogo del disastro,muore un motociclista mentre l’autista di un SUV finisce in coma. Entrambe le vittime si scoprono essere titolari della stessa azienda distrutta dall’incendio. La medesima sera, l’investigatore privato Giorgio Martinengo prende servizio come soccorritore della Croce Rossa e il suo migliore amico, il chimico Paolo Marchese, membro dell’ARPA Piemonte, deve intervenire per monitorare il potenziale pericolo d’inquinamento ambientale derivato dall’incendio,perché la funerea e irreale colonna di fumo nero come la pece che ascende al cielo della piccola città piemontese non sembra solo carta che brucia. Inizia così una lunga notte insonne, durante la quale Giorgio Martinengo si ritroverà a ricomporre un mosaico di fatti e persone in una sarabanda di morte che coinvolgerà i personaggi più inaspettati. Un vortice di faccendieri, corrotti ed ecomafie nel quale Martinengo, vittima di una insopprimibile brama di sapere, sarà coinvolto nonostante il suo inedito ruolo.
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