Eugene Koonin's Books

The Logic of Chance

The Nature and Origin of Biological Evolution

By: Eugene V. Koonin

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The Logic of Chance

The Nature and Origin of Biological Evolution

By: Eugene V. Koonin

The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and hypotheses on the key aspects of the evolution of life on earth in light of comparative genomics and systems biology. The author presents many specific examples from systems and comparative genomic analysis to begin to build a new, much more detailed, complex, and realistic picture of evolution. The book examines a broad range of topics in evolutionary biology including the inadequacy of natural selection and adaptation as the only or even the main mode of evolution; the key role of horizontal gene transfer in evolution and the consequent overhaul of the Tree of Life concept; the central, underappreciated evolutionary importance of viruses; the origin of eukaryotes as a result of endosymbiosis; the concomitant origin of cells and viruses on the primordial earth; universal dependences between genomic and molecular-phenomic variables; and the evolving landscape of constraints that shape the evolution of genomes and molecular phenomes. "Koonin's account of viral and pre-eukaryotic evolution is undoubtedly up-to-date. His "mega views" of evolution (given what was said above) and his cosmological musings, on the other hand, are interesting reading." Summing Up: Recommended Reprinted with permission from CHOICE, copyright by the American Library Association.

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530

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FT Press

Published Date

ISBN 10

013262317X

ISBN 13

9780132623179

The Logic of Chance

The Nature and Origin of Biological Evolution

By: Eugene V. Koonin

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The Logic of Chance

The Nature and Origin of Biological Evolution

By: Eugene V. Koonin

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530

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FT Press

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ISBN 10

013262317X

ISBN 13

9780132623179

Sequence — Evolution — Function

Computational Approaches in Comparative Genomics

By: Eugene V. Koonin,Michael Galperin

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Sequence — Evolution — Function

Computational Approaches in Comparative Genomics

By: Eugene V. Koonin,Michael Galperin

Sequence - Evolution - Function is an introduction to the computational approaches that play a critical role in the emerging new branch of biology known as functional genomics. The book provides the reader with an understanding of the principles and approaches of functional genomics and of the potential and limitations of computational and experimental approaches to genome analysis. Sequence - Evolution - Function should help bridge the "digital divide" between biologists and computer scientists, allowing biologists to better grasp the peculiarities of the emerging field of Genome Biology and to learn how to benefit from the enormous amount of sequence data available in the public databases. The book is non-technical with respect to the computer methods for genome analysis and discusses these methods from the user's viewpoint, without addressing mathematical and algorithmic details. Prior practical familiarity with the basic methods for sequence analysis is a major advantage, but a reader without such experience will be able to use the book as an introduction to these methods. This book is perfect for introductory level courses in computational methods for comparative and functional genomics.

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482

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1475737831

ISBN 13

9781475737837

The Hologenome Concept: Human, Animal and Plant Microbiota

By: Eugene Rosenberg,Ilana Zilber-Rosenberg

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The Hologenome Concept: Human, Animal and Plant Microbiota

By: Eugene Rosenberg,Ilana Zilber-Rosenberg

Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.

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187

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3319042416

ISBN 13

9783319042411

Microbiomes

Current Knowledge and Unanswered Questions

By: Eugene Rosenberg

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Microbiomes

Current Knowledge and Unanswered Questions

By: Eugene Rosenberg

This book examines an important paradigm shift in biology: Plants and animals, traditionally viewed as individuals, are now considered to be complex systems and host to a plethora of microorganisms. After first presenting historical aspects of microbiota research, bacterial compositions of individual microbiomes and the critical analysis of current methods, the book discusses how microbial communities inside the human body are profoundly affected by numerous factors, such as macro- and micro-nutrients, physical exercise, antibiotics, gender and age. As described by current research, the author highlights how microbiomes contribute to the fitness of the host by providing nutrients, inhibiting pathogens, aiding in the storage of fat during pregnancy, and contributing to development and behavior. The author not only focusses on prokaryotic components in microbiomes, but also addresses single-cell eukaryotes and viruses. This follow-up to the successful book The Hologenome Concept: Human, Animal and Plant Microbiota, published in 2013, provides a contemporary overview of microbiomes. It appeals to anyone working in the life sciences and biomedicine.

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Page Count

439

Publisher

Springer Nature

Published Date

ISBN 10

303065317X

ISBN 13

9783030653170

Environmental Microbiology

From Genomes to Biogeochemistry

By: Eugene L. Madsen

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Environmental Microbiology

From Genomes to Biogeochemistry

By: Eugene L. Madsen

New and expanded for its second edition, Environmental Microbiology: From Genomes to Biogeochemistry ̧ Second Edition, is a timely update to a classic text filled with ideas, connections, and concepts that advance an in-depth understanding of this growing segment of microbiology. Core principles are highlighted with an emphasis on the logic of the science and new methods-driven discoveries. Numerous up-to-date examples and applications boxes provide tangible reinforcement of material covered. Study questions at the end of each chapter require students to utilize analytical and quantitative approaches, to define and defend arguments, and to apply microbiological paradigms to their personal interests. Essay assignments and related readings stimulate student inquiry and serve as focal points for teachers to launch classroom discussions. A companion website with downloadable artwork and answers to study questions is also available. Environmental Microbiology: From Genomes to Biogeochemistry, Second Edition, offers a coherent and comprehensive treatment of this dynamic, emerging field, building bridges between basic biology, evolution, genomics, ecology, biotechnology, climate change, and the environmental sciences.

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Page Count

588

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118439635

ISBN 13

9781118439630

Coronavirus Capitalism Goes to the Cinema

By: Eugene Nulman

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Coronavirus Capitalism Goes to the Cinema

By: Eugene Nulman

Using innovative interpretations of recent big budget films, Coronavirus Capitalism Goes to the Cinema interrogates the social, political and economic landscape during and prior to the COVID-19 crisis and provides lessons for advancing progressive politics in a post-pandemic age. By exploring numerous films including Avengers: Endgame, Once Upon a Time... In Hollywood, 1917, and Parasite, this short book provides a deep understanding about neoliberal society in a time of crisis. Facilitated by the ideas of Emma Goldman, Naomi Klein, Karl Marx, Noam Chomsky and many more, these movies are reinterpreted to point out our political blind spots, combat our non-COVID contagions and inoculate us into ideological herd immunity. From explorations of the supervillain-like decision-making of our political leaders to the inequalities in infection outcomes that sparked further Black Lives Matter protests, this book discusses the central social challenges we face today through the sights and sounds of some of the most beloved films of the very recent past. This entertaining and accessible book will reward readers who are interested in contemporary politics in the context of COVID-19, as well as cinephiles and movie-goers who want fresh interpretations of instant classics to help explain the world around them. More than just informative and amusing, this book is a call to action to those activists who want social change in the face of coronavirus capitalism.

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Page Count

149

Publisher

Taylor & Francis

Published Date

ISBN 10

1000407675

ISBN 13

9781000407679

The Bubble Universe: Psychological Perspectives on Reality

By: Eugene Subbotsky

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The Bubble Universe: Psychological Perspectives on Reality

By: Eugene Subbotsky

This book examines the role that human subjective experience plays in the creation of reality and introduces a new concept, the Bubble Universe, to describe the universe as it looks from the subjective viewpoint of an individual. Drawing on a range of research, the author questions the extent to which the scientific study of the origins of life, consciousness and subjective experience is itself influenced by scientists’ subjective worlds. The author argues that in many respects the Bubble Universe differs from the universe as described by science and religion, and analyzes these differences. The fabric and structure of subjective reality is described, and various aspects of the Bubble Universe are examined, including science, religion, life, morality and history. The differences between the views from inside the subjective universe and from scientific, religious and sociocultural versions of the universe are outlined, and their significance for practical and theoretical problems are highlighted and illustrated with psychological experiments. This book will be of value to all scholars interested in how subjectivity influences research and appeal in particular to those working in developmental and theoretical psychology, consciousness, epistemology, phenomenology, and the philosophy of science and of the mind.

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Page Count

393

Publisher

Springer Nature

Published Date

ISBN 10

3030490084

ISBN 13

9783030490089

Sequence — Evolution — Function

Computational Approaches in Comparative Genomics

By: Eugene V. Koonin,Michael Galperin

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Sequence — Evolution — Function

Computational Approaches in Comparative Genomics

By: Eugene V. Koonin,Michael Galperin

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Page Count

482

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Springer Science & Business Media

Published Date

ISBN 10

1475737831

ISBN 13

9781475737837

Sequence — Evolution — Function

Computational Approaches in Comparative Genomics

By: Eugene Koonin,Michael Y. Galperin

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Sequence — Evolution — Function

Computational Approaches in Comparative Genomics

By: Eugene Koonin,Michael Y. Galperin

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Page Count

462

Publisher

Springer

Published Date

ISBN 10

147573784X

ISBN 13

9781475737844

Power Laws, Scale-Free Networks and Genome Biology

By: Eugene V. Koonin,Yuri Wolf,Georgy Karev

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Power Laws, Scale-Free Networks and Genome Biology

By: Eugene V. Koonin,Yuri Wolf,Georgy Karev

Power Laws, Scale-free Networks and Genome Biology deals with crucial aspects of the theoretical foundations of systems biology, namely power law distributions and scale-free networks which have emerged as the hallmarks of biological organization in the post-genomic era. The chapters in the book not only describe the interesting mathematical properties of biological networks but moves beyond phenomenology, toward models of evolution capable of explaining the emergence of these features. The collection of chapters, contributed by both physicists and biologists, strives to address the problems in this field in a rigorous but not excessively mathematical manner and to represent different viewpoints, which is crucial in this emerging discipline. Each chapter includes, in addition to technical descriptions of properties of biological networks and evolutionary models, a more general and accessible introduction to the respective problems. Most chapters emphasize the potential of theoretical systems biology for discovery of new biological phenomena.

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Page Count

274

Publisher

Springer Science & Business Media

Published Date

ISBN 10

0387339167

ISBN 13

9780387339160

Book's by Eugene Koonin

The Logic of Chance

The Logic of Chance

The Logic of Chance

The Logic of Chance

Sequence — Evolution — Function

Sequence — Evolution — Function

The Hologenome Concept: Human, Animal and Plant Microbiota

The Hologenome Concept: Human, Animal and Plant Microbiota

Microbiomes

Microbiomes

Environmental Microbiology

Environmental Microbiology

Coronavirus Capitalism Goes to the Cinema

Coronavirus Capitalism Goes to the Cinema

The Bubble Universe: Psychological Perspectives on Reality

The Bubble Universe: Psychological Perspectives on Reality

Sequence — Evolution — Function

Sequence — Evolution — Function

Sequence — Evolution — Function

Sequence — Evolution — Function

Power Laws, Scale-Free Networks and Genome Biology

Power Laws, Scale-Free Networks and Genome Biology

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