Estelle Collin's Books

Cells and Biomaterials for Intervertebral Disc Regeneration

By: Sibylle Grad,Mauro Alini,David Eglin,Daisuke Sakai

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Cells and Biomaterials for Intervertebral Disc Regeneration

By: Sibylle Grad,Mauro Alini,David Eglin,Daisuke Sakai

Disorders related to the intervertebral disc (IVD) are common causes of morbidity and of severe life quality deterioration. IVD degeneration, although in many cases asymptomatic, is often the origin of painful neck and back diseases. In Western societies IVD related pain and disability account for enormous health care costs as a result of work absenteeism and thus lost production, disability benefits, medical and insurance expenses. Although only a small percentage of patients with disc disorders finally will undergo surgery, spinal surgery has been one of the fastest growing disciplines in the musculoskeletal field in recent years. Nevertheless, current treatment options are still a matter of controversial discussion. In particular, they hardly can restore normal spine biomechanics and prevent degeneration of adjacent tissues. While degeneration affects all areas of the IVD, the most constant and noticeable changes occur in the gel-like central part, the nucleus pulposus (NP). Recent emphasis has therefore been put in biological ways to regenerate the NP; however, there are a number of obstacles to overcome, considering the exceptional biological and biomechanical environment of this tissue. Different biological approaches such as molecular, gene, and cell based therapies have been investigated and have shown promising results in both in vitro and in vivo studies. Nonetheless, considerable hurdles still exist in their application for IVD regeneration in human patients. The choice of the cells and the choice of the cell carrier suitable for implantation pose major challenges for research and development activities. This lecture recapitulates the basics of IVD structure, function, and degeneration mechanisms. The first part reviews the recent progress in the field of disc and stem cell based regenerative approaches. In the second part, most appropriate biomaterials that have been evaluated as cell or molecule carrier to cope with degenerative disc disease are outlined. The potential and limitations of cell- and biomaterial-based treatment strategies and perspectives for future clinical applications are discussed. Table of Contents: Cell Therapy for Nucleus Pulposus Regeneration / Recent Advances in Biomaterial Based Tissue Engineering for Intervertebral Disc Regeneration

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Springer Nature

Published Date

ISBN 10

3031025806

ISBN 13

9783031025808

The Palm Beach Palace

And Other Stories

By: Estelle Craig

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The Palm Beach Palace

And Other Stories

By: Estelle Craig

When Leslie Harper decided to become a resident of the Palm Beach Palace Hotel in Palm Beach, Florida, she had no idea how her life would change. Leslie Harper had lost her husband, and soon she found that her big house was too large for one person. She decided to look into the Palm Beach Palace, a hotel catering mostly to seniors, which she had passed many times but had never entered. She made an appointment to see what it was like and how much she really liked the idea of being with people who, like herself, wanted their privacy. But when she wanted the pleasure of being with other people, then she was ready to mix with company. She entered the building and found it to be what she expected. It would be quite manageable. And she knew that if she wanted to be private, she could retreat to her apartment. On the other hand, if she wanted to be with people, she could go downstairs and see others like herself, where she could carry on with the other residents. So she signed a year’s lease. As soon as she packed her belongings and moved in, she found that she had done the right thing. Yes, indeed, she had done the right thing.

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Page Count

137

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AuthorHouse

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ISBN 10

1546243089

ISBN 13

9781546243083

As I Was Saying

People Places and Things

By: Estelle Craig

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As I Was Saying

People Places and Things

By: Estelle Craig

After a lifetime full of adventure, travel and meeting celebrities and fascinating people all over the world, Estelle Craig has selected a few people, places and things from her memories. Unforgettable was her time spent with the duke of Bedford and Prime Minister Clement Attlee! But her Prime memories are of her three children and eleven great grandchildren and of course her husband Louis D. Craig.

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105

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Author House

Published Date

ISBN 10

1468546260

ISBN 13

9781468546262

The Diary of a 100 Year Old Amused Senior

By: Estelle Craig

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The Diary of a 100 Year Old Amused Senior

By: Estelle Craig

Stroll down memory lane with Estelle Craig at the age of one hundred, as she recalls her childhood, life as a new bride, a columnist, an impresario, a radio host, a publisher, and a playwright. Travel around the world and meet celebrities. Find out how it can be fun to be a senior.

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111

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AuthorHouse

Published Date

ISBN 10

1496974530

ISBN 13

9781496974532

Abstract of Early Kentucky Wills and Inventories

By: Junie Estelle Stewart King

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Abstract of Early Kentucky Wills and Inventories

By: Junie Estelle Stewart King

Mrs. King has here abstracted the earliest wills of 38 Kentucky counties formed between the years 1780 and 1842 (with the exception of Crittenden County) and representing the state as a whole. The information given includes dates of instrument and probate, names of wife and children, and names of witnesses. The arrangement is county by county, each with its own index, with a general index at the rear of the book containing all the names mentioned in the text. The following Kentucky counties are within the scope of the work: Barren, Bourbon, Bullitt, Caldwell, Christian, Clark, Crittenden, Daviess, Fayette, Franklin, Gallatin, Garrard, Greene, Hardin, Harrison, Henderson, Henry, Hopkins, Jefferson, Jessamine, Knox, Lincoln, Livingston, Logan, Madison, McCracken, Mercer, Muhlenberg, Nelson, Nicholas, Ohio, Scott, Shelby, Spencer, Todd, Warren, Washington, and Woodford..

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Page Count

306

Publisher

Genealogical Publishing Com

Published Date

ISBN 10

080630202X

ISBN 13

9780806302027

Historic Hood County

An Illustrated History

By: Mary Estelle Gott Salterelli

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Historic Hood County

An Illustrated History

By: Mary Estelle Gott Salterelli

An illustrated history of Hood County, Texas, paired with histories of the local companies.

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127

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HPN Books

Published Date

ISBN 10

1935377086

ISBN 13

9781935377085

Cells and Biomaterials for Intervertebral Disc Regeneration

By: Sibylle Grad,Mauro Alini,David Eglin,Daisuke Sakai

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Cells and Biomaterials for Intervertebral Disc Regeneration

By: Sibylle Grad,Mauro Alini,David Eglin,Daisuke Sakai

Average ratings

N/A

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Solve jigsaw puzzle

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Publisher

Springer Nature

Published Date

ISBN 10

3031025806

ISBN 13

9783031025808

Book's by Estelle Collin

Cells and Biomaterials for Intervertebral Disc Regeneration

Cells and Biomaterials for Intervertebral Disc Regeneration

The Palm Beach Palace

The Palm Beach Palace

As I Was Saying

As I Was Saying

The Diary of a 100 Year Old Amused Senior

The Diary of a 100 Year Old Amused Senior

Abstract of Early Kentucky Wills and Inventories

Abstract of Early Kentucky Wills and Inventories

Historic Hood County

Historic Hood County

Cells and Biomaterials for Intervertebral Disc Regeneration

Cells and Biomaterials for Intervertebral Disc Regeneration

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