This volume is a critical exposition of the data and analyses from a full decade of rigorous research into how age-related changes at the individual level, along with other factors, contribute to morbidity, disability and mortality risks at the broader population level. After summarizing the state of our knowledge in the field, individual chapters offer enlightening discussion on a range of key topics such as age trajectory analysis in select and general populations, incidence/age patterns of major chronic illnesses, and indices of cumulative deficits and their use in characterizing and understanding the detailed properties of individual aging. The book features comprehensive statistical analyses of unique longitudinal data sets including the unique resource of the Framingham Heart Study, with its more than 60 years of follow-up. Culminating in penetrating conclusions about the insights gained from the work involved, this book adds much to our understanding of the links between aging and human health.
This selection of papers encompasses recent methodological advances in several important areas, such as multivariate failure time data and interval censored data, as well as innovative applications of the existing theory and methods. Using a rigorous account of statistical forecasting efforts that led to the successful resolution of the John-Manville asbestos litigation, the models in this volume can be adapted to forecast industry-wide asbestos liability. More generally, because the models are not overly dependent on the U.S. legal system and the role of asbestos, this volume will be of interest in other product liability cases, as well as similar forecasting situations for a range of insurable or compensational events. Throughout the text, the emphasis is on the iterative nature of model building and the uncertainty generated by lack of complete knowledge of the injury process. This uncertainty is balanced against the court's need for a definitive settlement, and how these opposing principles can be reconciled. A valuable reference for researchers and practitioners in the field of survival analysis.
The theory of holomorphic dynamical systems is a subject of increasing interest in mathematics, both for its challenging problems and for its connections with other branches of pure and applied mathematics. A holomorphic dynamical system is the datum of a complex variety and a holomorphic object (such as a self-map or a vector ?eld) acting on it. The study of a holomorphic dynamical system consists in describing the asymptotic behavior of the system, associating it with some invariant objects (easy to compute) which describe the dynamics and classify the possible holomorphic dynamical systems supported by a given manifold. The behavior of a holomorphic dynamical system is pretty much related to the geometry of the ambient manifold (for instance, - perbolic manifolds do no admit chaotic behavior, while projective manifolds have a variety of different chaotic pictures). The techniques used to tackle such pr- lems are of variouskinds: complexanalysis, methodsof real analysis, pluripotential theory, algebraic geometry, differential geometry, topology. To cover all the possible points of view of the subject in a unique occasion has become almost impossible, and the CIME session in Cetraro on Holomorphic Dynamical Systems was not an exception.
“A welcome new account of Stuart’s fateful ride during the 1863 Pennsylvania campaign . . . well researched, vividly written, and shrewdly argued.” —Mark Grimsley, author of And Keep Moving On June 1863. The Gettysburg Campaign is in its opening hours. Harness jingles and hoofs pound as Confederate cavalryman James Ewell Brown (JEB) Stuart leads his three brigades of veteran troopers on a ride that triggers one of the Civil War’s most bitter and enduring controversies. Instead of finding glory and victory-two objectives with which he was intimately familiar, Stuart reaped stinging criticism and substantial blame for one of the Confederacy’s most stunning and unexpected battlefield defeats. In Plenty of Blame to Go Around: Jeb Stuart’s Controversial Ride to Gettysburg, Eric J. Wittenberg and J. David Petruzzi objectively investigate the role Stuart’s horsemen played in the disastrous campaign. It is the first book ever written on this important and endlessly fascinating subject. Did the plumed cavalier disobey General Robert E. Lee’s orders by stripping the army of its “eyes and ears?” Was Stuart to blame for the unexpected combat that broke out at Gettysburg on July 1? Authors Wittenberg and Petruzzi, widely recognized for their study and expertise of Civil War cavalry operations, have drawn upon a massive array of primary sources, many heretofore untapped, to fully explore Stuart’s ride, its consequences, and the intense debate among participants shortly after the battle, through early post-war commentators, and among modern scholars. The result is a richly detailed study jammed with incisive tactical commentary, new perspectives on the strategic role of the Southern cavalry, and fresh insights on every horse engagement, large and small, fought during the campaign.
The dominant political theme of the State of Israel is the perpetual quest for security. In its first 25 years, Israel experienced five wars with Arab states declaring their goal to destroy Israel. In American Christian Support for Israel:Standing with the Chosen People, 1948–1975, Eric R. Crouse examines how American Christians responded to Israel’s wars and the persistent threats to its security. While some were quick to condemn Israel as it made difficult and unpopular decisions in its fight for survival in a hostile region, conservative Christians were trustworthy supporters, routinely voicing uplifting reports. Crouse argues that Israel’s embodiment of western ideals and its remarkable economic development gave conservative Christians good reasons to favor Israel in a troubled Middle East, but the main reason for their unconditional support was the key biblical text of Christian Zionism: “I will bless those who bless you [Abraham and his descendants], and I will curse him who curses you” (Genesis 12:3).
Consultant eye surgeon, Eric Arnott, was one of the original pioneers of small-incision surgery. He was the first to perform modern Phaco surgery in Europe and designed lens implants that have restored the sight to millions of patients. The word autobiography is simply insufficient to describe this book, which is a remarkable testament to the life, works and marriage of a remarkable man. The book details the original invention of the lens implant by Harold Ridley, who Eric worked with in his early years of medical training. It goes on to follow the development of small-incision Phaco surgery, instigated by Charlie Kelman, and the disinterest and contempt held by the peers of these ophthalmologic pioneers. The author describes every advance in this field of ophthalmology in fascinating detail. The importance to Eric of religion, spirituality, family life and helping others less fortunate than himself is reinforced in this enthralling and at times very amusing read. Arnott draws you into his narrative, rousing thoughts of disbelief as you are compelled to continue reading, each new chapter and event in his life proving as fascinating as the last. Entertaining and illuminating, A New Beginning in Sight provides a detailed history of ophthalmology and is essential reading for ophthalmologists, other specialists and non-specialists alike.
Before they became household names, many would-be Hollywood stars began their careers as small-time actors in regional theatres and playhouses. Few of them earned much recognition based on their time in the footlights, but often the stage provided these Hollywood hopefuls with their first break in show business. Drawing on material from the J. Willis Sayre Collection, a nearly unbroken accumulation of theatrical programs from 1865 to 1955, this book chronicles the Seattle stage engagements of more than 30 silent film personalities. Such Hollywood giants as Douglas Fairbanks, Charlie Chaplin, Cecil B. DeMille, D.W. Griffith, and Buster Keaton, to name just a few, can trace their early careers through the Emerald City.
Eric Engel and Stylianos Antonarakis have written the most authoritative and vital reference on molecular and clinical aspects of uniparental disomy (UPD) and genomic imprinting to date. Genomic Imprinting and Uniparental Disomy in Medicine features comprehensive overviews of a multitude of genetic disorders linked to UPD, with a strong emphasis on clinical consequences. This book will provide readers with the tools necessary to identify and treat diseases associated with nontraditional chromosomal inheritance. Genomic Imprinting and Uniparental Disomy in Medicine features handy tables summarizing clinical phenotypes and chromosomal involvement in UPD, as well as clear illustrations on imprinting mechanisms and diagnostic testing. This authoritative, completely up-to-date practical reference will be useful for any clinical geneticist, genetic counselor, physician, or researcher encountering patients with such disorders or studying complex disease mechanisms.
Drawing from research, experience, and real school success stories, this galvanizing book explores engagement as the key factor in the academic success of economically disadvantaged students.
Written by an experienced business lawyer in the technology, scientific and engineering community, this publication is for the engineer with an innovative high-tech idea or concept who needs those crucial business insights and strategies to move that idea forward. It offers key analysis on how to leave a current employer, gain access to technologie
Ethical Considerations When Preparing a Clinical Research Protocol, Second Edition, provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. It includes practical information on ethical principles in clinical research, how to design appropriate research studies, how to consent and assent documents, how to get protocols approved, special populations, confidentiality issues, and the reporting of adverse events. The book's valuable appendix includes a listing of web resources about research ethics, along with a glossary, making it an invaluable resource for scientists collaborating in clinical trials, physician investigators, clinical research fellows, and more. - Walks investigators and trainees through the identification of the ethical aspects of each section of a clinical research protocol - Includes case histories that illustrate key points - Contains information on conducting clinical research within the pharmaceutical industry - Includes internet resources and worldwide web addresses for important research ethics documents and regulations - Contains a chapter on Study Design and Methodology that is purposely expanded to explicitly address biostatistical considerations
From the remote villages of Afghanistan to the depths of the ocean, Lieutenant Commander Grant Chisolm is on a mission to thwart jihadists. His latest assignment as liaison officer to Guantanamo brings him face to face with the Taliban and Al-Qaeda, and their hatred of the United States, once more. Dive into the explosive world of terrorism and those fearless enough to fight it in Killing Sharks. "In the best tradition of the works of Frederick Forsyth and Dan Brown, Killing Sharks: De Profundis is a thriller that takes the reader from the desolate mountains of the FATA on the Afghan-Pakistani border to the warm waters of the Caribbean and the base prison at Guantanamo, Cuba. Navy SEAL, Lieutenant Commander Grant Chisolm, races against the timing of suicide bombers and through the murky world of the modern war on terrorism and the backwaters of the Cold War. Wentz's work is authentic. It's the product of a navy officer who has seen Guantanamo and the world-wide war on terror firsthand." Dr. Ralph L. DeFalco III, Senior Strategist, Joint and Coalition Warfighter Support, Under Secretary of Defense for Intelligence, Captain, USNR
Award-winning authors Scott L. Mingus Sr. and Eric J. Wittenberg are back with the second and final installment of “If We Are Striking for Pennsylvania”: The Army of Northern Virginia’s and Army of the Potomac’s March to Gettysburg. This compelling and bestselling study is the first to fully integrate the military, political, social, economic, and civilian perspectives with rank-and-file accounts from the soldiers of both armies during the inexorably march north toward their mutual destinies at Gettysburg. Gen. Robert E. Lee’s bold movement north, which began on June 3, shifted the war out of the central counties of the Old Dominion into the Shenandoah Valley, across the Potomac, and beyond. The first installment (June 3-22, 1863) carried the armies through the defining mounted clash at Battle of Brandy Station, after which Lee pushed his corps into the Shenandoah Valley and achieved the magnificent victory at Second Winchester on his way to the Potomac. Caught flat-footed, Maj. Gen. Joseph Hooker used his cavalry to probe the mountain gaps, triggering a series of consequential mounted actions. The current volume (June 23-30) completes the march to Gettysburg and details the actions and whereabout of each component of the armies up to the eve of the fighting. The large-scale maneuvering in late June prompted General Hooker to move his Army of the Potomac north after his opponent and eventually above the Potomac, where he loses his command to the surprised Maj. Gen. George G. Meade. Jeb Stuart begins his controversial and consequential ride that strips away the eyes and ears of the Virginia army. Throughout northern Virginia, central Maryland, and south-central Pennsylvania, civilians and soldiers alike struggle with the reality of a mobile campaign and the massive logistical needs of the armies. Untold numbers of reports, editorials, news articles, letters, and diaries describe the passage of the long martial columns, the thunderous galloping of hooves, and the looting, fighting, suffering, and dying. Mingus and Wittenberg mined hundreds of primary accounts, newspapers, and other sources to produce this powerful and gripping saga. As careful readers will quickly discern, other studies of the runup to Gettysburg gloss over most of this material. It is simply impossible to fully grasp and understand the campaign without a firm appreciation of what the armies and the civilians did during the days leading up to the fateful meeting at the small crossroads town in Adams County, Pennsylvania.
Written by a practicing business attorney with startup experience in the environmental and technology sectors, this comprehensive handbook assists entrepreneurs in tackling the wide variety of opportunities to go green. A one-stop resource for entrepreneurs, it helps readers incorporate clean technology, environmental practices, and green business approaches into the work environment. The book discusses how to sell to utilities, explores fundraising outlets for green businesses, covers government incentives, presents key startup tools aimed at green businesses, and addresses challenges of many new businesses, such as raising money and making sales. Additional resources are available on the book's website.
Trusted for decades by Physical Therapy students as well as experienced therapists who want to improve their knowledge, Tecklin’s Pediatric Physical Therapy provides a comprehensive and logical overview of some of the most common pediatric physical therapy diagnoses. This straightforward approach presents basic medical information regarding common clinical diagnostic categories followed by coverage of physical therapy examination, intervention and special considerations within each diagnostic group. Content in this 6th Edition has been thoroughly updated and reorganized to help prepare students for today’s clinical challenges, accompanied by case studies and interactive features that reinforce understanding and instill the clinical decision-making skills essential to successful practice.
Water. It’s in nearly every book of the Bible! The world was made from water and was flooded by it. People were both killed and saved by it. Life requires water. It was in Eden and will be in the New Jerusalem. Moses, David, and most of the Old Testament prophets spoke about it, as did Jesus, Peter, and John. So why has no one yet figured out what all this water talk is about? God is revealing something exciting using water as his means of communication. In this book nearly all the uses of water throughout the Bible have been examined and organized into common categories. The mentions of water have ramifications for other major biblical teachings such as on the work of the Holy Spirit, salvation, and baptism. This work unveils something that has remained hidden to most until now: a biblical theology of water.
In this hugely ambitious history of Britain, Eric Evans surveys every aspect of the period in which the country was transformed into the world’s first industrial power. This was an era of revolutionary change unparalleled in Britain, yet one in which transformation was achieved without political revolution. The unique combination of transition and revolution is a major theme in the book, which ranges across the embryonic empire, the Church, education, health, finance, and rural and urban life. Evans gives particular attention to the Great Reform Act of 1832. The Third Edition includes an entirely new introductory chapter, and is illustrated for the first time.
Rutter’s Child and Adolescent Psychiatry has become an established and accepted textbook of child psychiatry. Now completely revised and updated, the fifth edition provides a coherent appraisal of the current state of the field to help trainee and practising clinicians in their daily work. It is distinctive in being both interdisciplinary and international, in its integration of science and clinical practice, and in its practical discussion of how researchers and practitioners need to think about conflicting or uncertain findings. This new edition now offers an entirely new section on conceptual approaches, and several new chapters, including: neurochemistry and basic pharmacology brain imaging health economics psychopathology in refugees and asylum seekers bipolar disorder attachment disorders statistical methods for clinicians This leading textbook provides an accurate and comprehensive account of current knowledge, through the integration of empirical findings with clinical experience and practice, and is essential reading for professionals working in the field of child and adolescent mental health, and clinicians working in general practice and community pediatric settings.
The Third Edition of Radiation Therapy Physics addresses in concise fashion the fundamental diagnostic radiologic physics principles as well as their clinical implications. Along with coverage of the concepts and applications for the radiation treatment of cancer patients, the authors have included reviews of the most up-to-date instrumentation and critical historical links. The text includes coverage of imaging in therapy planning and surveillance, calibration protocols, and precision radiation therapy, as well as discussion of relevant regulation and compliance activities. It contains an updated and expanded section on computer applications in radiation therapy and electron beam therapy, and features enhanced user-friendliness and visual appeal with a new, easy-to-follow format, including sidebars and a larger trim size. With its user-friendly presentation and broad, comprehensive coverage of radiotherapy physics, this Third Edition doubles as a medical text and handy professional reference.
Today, most trial lawyers and consultants accept the fact that all legal decision makers decide cases by first making up their own version of the case story. Yet, few have yet to fully adjust their practices to meet the demands of that reality. Facts Still Can’t Speak for Themselves offers specific methods for trial professionals to increase their reach into the full range of potential stories decision makers can construct (and will construct) during any single case, and then shows you how to refine those stories into the one most compelling presentation for any legal decision maker to judge, in any legal decision-making venue. What you’ll find inside: * How the stories decision makers imagine affect verdicts as much as their backgrounds and beliefs or the attorney’s presentation in court * Which focus group method reveals the real range of stories decision makers can build from your case * How to profitably apply focus group results in negotiations and mediation equally well as in trials * How to run voir dire like a focus group (and a focus group like voir dire) improving both in the processand how to avoid common misleading mistakes * How focus group deliberations are the least valuable part of the process * How asking focus group participants which side in a case they “like” could be a major mistake * Why you should think twice before ever again asking a “why” question or using the word “any” during voir dire or in focus groups * How to establish immediate rapport with decision makers and to manage how they build their perceptions of your client’s case storyin time to affect their final judgments In this new edition, Eric Oliver dives deeply into cutting-edge research in communication, human judgment, perception, and influence and breaks down the process of turning theoretical abstractions into effective persuasive practices that help legal decision makers hearand seethe case story from your client’s point of view. Each chapter is now supplemented with some of the most relevant developments in the science of decision making, as well as with the decade of additional experience Eric has acquired working with trial lawyers and their clients since the first edition was published in 2005.
A broad treatment of the cultural, social, political, and literary under-pinnings of an entire period and movement in American letters The Vast and Terrible Drama is a critical study of the context in which authors such as Oliver Wendell Holmes, Stephen Crane, Frank Norris, Theodore Dreiser, and Jack London created their most significant work. In 1896 Frank Norris wrote: "Terrible things must happen to the characters of the naturalistic tale. They must be twisted from the ordinary . . . and flung into the throes of a vast and terrible drama." There could be "no teacup tragedies here." This volume broadens our understanding of literary naturalism as a response to these and other aesthetic concerns of the 19th century. Themes addressed include the traditionally close connection between French naturalism and American literary naturalism; relationships between the movement and the romance tradition in American literature, as well as with utopian fictions of the 19th century; narrative strategies employed by the key writers; the dominant naturalist theme of determinism; and textual readings that provide broad examples of the role of the reader. By examining these and other aspects of American literary naturalism, Link counters a century of criticism that has perhaps viewed literary naturalism too narrowly, as a subset of realism, bound by the conventions of realistic narration.
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