Cellular Internet of Things: Technologies, Standards and Performance gives insight into the recent work performed by the 3rd Generation Partnership Project (3GPP) to develop systems for the Cellular Internet of Things. It presents both the design of the new Narrowband Internet of Things (NB-IoT) technology and how GSM and LTE have evolved to provide Cellular Internet of Things services. The criteria used for the design and objectives of the standardization work are explained, and the technical details and performance of each technology is presented. This book discusses the overall competitive landscape for providing wireless connectivity, also introducing the most promising technologies in the market. Users will learn how cellular systems work and how they can be designed to cater to challenging new requirements that are emerging in the telecom industry, what the physical layers and procedures in idle and connected mode look like in EC-GSM-IoT, LTE-M, and NB-IoT, and what the expected performance of these new systems is in terms of expected coverage, battery lifetime, data throughput, access delay time and device cost. Learn: How cellular systems work, and how they can be designed to cater for challenging new requirements emerging in the telecom industry. How the physical layers and the procedures in idle and connected mode look like in EC-GSM-IoT, LTE-M, and NB-IoT. What the expected performance of these new systems is in terms of expected coverage, battery lifetime, data throughput, access delay time, and device cost. How the Low-Power-Wide-Area IoT market segment looks like and how different available solutions compare in terms of performance and compatibility with already existing radio networks. What system capacity and network level performance can be achieved when deploying these new systems, and in addition what deployment options are possible. Provides a detailed introduction to the EC-GSM-IoT, LTE-M and NB-IoT technologies Presents network performance of the 3GPP cellular technologies, along with an analysis of the performance of non-cellular alternatives operating in unlicensed spectrum Includes prediction of true performance levels using state-of-the-art simulation models developed in the 3GPP standardization process
Providing an expert overview of the current structure of health care and how it affects today’s orthopaedic surgeons, Value-Based Health Care in Orthopaedics addresses the healthcare system’s transition from a fee-for-service model to value-based health care. This transition aligns the incentives of all stakeholders, including payers, purchasers, clinicians, and most importantly, patients, by prioritizing health over care, and facilitating competition based on health outcomes and cost. Developed in partnership with the American Academy of Orthopaedic Surgeons (AAOS) and edited by Eric C. Makhni, MD, MBA, FAAOS, Benedict Nwachukwu, MD, MBA, and Kevin J. Bozic, MD, MBA, FAAOS, this unique, authoritative text covers essential information not often covered in medical school or orthopaedic residency training—offering a comprehensive discussion of the principles of value-based health care as applied to orthopaedics.
The recent introduction of the “nano” dimension to pyrotechnics has made it possible to develop a new family of highly reactive substances: nanothermites. These have a chemical composition that is comparable to that of thermites at submillimeter or micrometric granulometry, but with a morphology having a much increased degree of homogeneity. This book discusses the methods of preparation of these energetic nanomaterials, their specific properties, and the different safety aspects inherent in their manipulation.
In a wide-ranging theory of the way people function, the author shows how their inner lives depend upon and in turn influence their commitments to goals or incentives.
In this wide-ranging history of modern Britain, Eric Evans surveys every aspect of the period in which Britain was transformed into the world's first industrial power. By the end of the nineteenth century, Britain was still ruled by wealthy landowners, but the world over which they presided had been utterly transformed. It was an era of revolutionary change unparalleled in Britain - yet that change was achieved without political revolution. Ranging across the developing empire, and dealing with such central institutions as the church, education, health, finance and rural and urban life, The Shaping of Modern Britain provides an unparallelled account of Britain's rise to superpower status. Particular attention is given to the Great Reform Act of 1832, and the implications of the 1867 Reform Act are assessed. The book discusses: - the growing role of the central state in domestic policy making - the emergence of the Labour party - the Great Depression - the acquisition of a vast territorial empire Comprehensive, informed and engagingly written, The Shaping of Modern Britain will be an invaluable introduction for students of this key period of British history.
American medicine attracts some of the brightest and most motivated people the country has to offer, and it boasts the most advanced medical technology in the world, a wondrous parade of machines and techniques such as PET scans, MRI, angioplasty, endoscopy, bypasses, organ transplants, and much more besides. And yet, writes Dr. Eric Cassell, what started out early in the century as the exciting conquest of disease, has evolved into an overly expensive, over technologized, uncaring medicine, poorly suited to the health care needs of a society marked by an aging population and a predominance of chronic diseases. In Doctoring: The Nature of Primary Care Medicine, Dr. Cassell shows convincingly how much better fitted advanced concepts of primary care medicine are to America's health care needs. He offers valuable insights into how primary care physicians can be better trained to meet the needs of their patients, both well and sick, and to keep these patients as the focus of their practice. Modern medical training arose at a time when medical science was in ascendancy, Cassell notes. Thus the ideals of science--objectivity, rationality--became the ideals of medicine, and disease--the target of most medical research--became the logical focus of medical practice. When clinicians treat a patient with pneumonia, they are apt to be thinking about pneumonia in general--which is how they learn about the disease--rather than this person's pneumonia. This objective, rational approach has its value, but when it dominates a physician's approach to medicine, it can create problems. For instance, treating chronic disease--such as rheumatoid arthritis, diabetes, stroke, emphysema, and congestive heart failure--is not simply a matter of medical knowledge, for it demands a great deal of effort by the patients themselves: they have to keep their doctor appointments, take their medication, do their exercises, stop smoking. The patient thus has a profound effect on the course of the disease, and so for a physician to succeed, he or she must also be familiar with the patient's motivations, values, concerns, and relationship with the doctor. Many doctors eventually figure out how to put the patient at the center of their practice, but they should learn to do this at the training level, not haphazardly over time. To that end, the training of primary care physicians must recognize a distinction between doctoring itself and the medical science on which it is based, and should try to produce doctors who rely on both their scientific and subjective assessments of their patients' overall needs. There must be a return to careful observational and physical examination skills and finely tuned history taking and communication skills. Cassell also advocates the need to teach the behavior of both sick and well persons, evaluation of data from clinical epidemiology, decision making skills, and preventive medicine, as well as actively teaching how to make technology the servant rather than the master, and offers practical tips for instruction both in the classroom and in practice. Most important, Doctoring argues convincingly that primary care medicine should become a central focus of America's health care system, not merely a cost-saving measure as envisioned by managed care organizations. Indeed, Cassell shows that the primary care physician can fulfill a unique role in the medical community, and a vital role in society in general. He shows that primary care medicine is not a retreat from scientific medicine, but the natural next step for medicine to take in the coming century.
Addressing the problems facing medicine and medical education Cassell discusses the new generalism and the skills that physicians-in-training must be taught in order to practice the art of doctoring which centres on the person not the disease.
A comprehensive treatment of visual ecology Visual ecology is the study of how animals use visual systems to meet their ecological needs, how these systems have evolved, and how they are specialized for particular visual tasks. Visual Ecology provides the first up-to-date synthesis of the field to appear in more than three decades. Featuring some 225 illustrations, including more than 140 in color, spread throughout the text, this comprehensive and accessible book begins by discussing the basic properties of light and the optical environment. It then looks at how photoreceptors intercept light and convert it to usable biological signals, how the pigments and cells of vision vary among animals, and how the properties of these components affect a given receptor's sensitivity to light. The book goes on to examine how eyes and photoreceptors become specialized for an array of visual tasks, such as navigation, evading prey, mate choice, and communication. A timely and much-needed resource for students and researchers alike, Visual Ecology also includes a glossary and a wealth of examples drawn from the full diversity of visual systems. The most up-to-date overview of visual ecology available Features some 225 illustrations, including more than 140 in color, spread throughout the text Guides readers from the basic physics of light to the role of visual systems in animal behavior Includes a glossary and a wealth of real-world examples
Scientists largely attribute the recent deterioration of the electromagnetic environment to power electronics. This realization has spurred the study of methodical approaches to electromagnetic compatibility designs as explored in this text. The book addresses major challenges, such as handling numerous parameters vital to predicting electro magnetic effects and achieving compliance with line-harmonics norms, while proposing potential solutions.
A trenchant account of an unacknowledged driver of inequality and wage stagnation in America: the failure of antitrust law to prevent the consolidation of employers, who use their market power to suppress wages. Since the 1970s, Americans have seen inequality skyrocket--and job opportunities stagnate. There are many theories of why this happened, including the decline of organized labor, changes in technology, and the introduction of tax policies that favored the rich. A missing piece of the puzzle is the consolidation of employers, which has resulted in limited competition in labor markets. This should have been addressed by antitrust law, but was not. In How Antitrust Law Failed Workers, Eric Posner documents the failure of antitrust law to address labor market concentration. Only through reforming antitrust law can we shield workers from employers' overwhelming market power. Antitrust law is well-known for its role in combatting mergers, price-fixing arrangements, and other anticompetitive actions in product markets. By opposing these practices, antitrust law enhances competition among firms and keeps prices low for goods and services. Less well-known, antitrust law also applies to anticompetitive conduct by employers in labor markets, which pushes wages below the competitive rate. Yet there have been few labor market cases or enforcement actions, and almost no scholarly commentary on the role of antitrust law in labor markets. This book fills the gap. It explains why antitrust law has failed to address labor market concentration, and how it can be reformed so that it does a better job. Essential reading for anyone interested in fighting economic inequality, How Antitrust Failed Workers also offers a sharp primer on the true nature of the American economyDLone that is increasingly uncompetitive and tilted against workers.
Netter’s Sports Medicine, by Christopher C. Madden, MD, Margot Putukian, MD, FACSM, Craig C. Young, MD, and Eric C. McCarty, MD, is a reference designed to help you meet the challenges presented by your patients in this growing interdisciplinary field. More than 1,000 Netter images, along with photos of physical examination techniques and imaging examples, provide a rich visual understanding, while a bulleted text format, combined with a user-friendly organization by specific types of injuries as well as different types of sports, makes reference quick and easy. Discussions of a full range of sports—traditional as well as less common—ensure that the coverage is comprehensive and up to date. From pre-participation exams, musculoskeletal injuries, sports nutrition, and sports psychology...to general medical problems in athletes...this reference equips you with the guidance you need to keep your patients at the top of their game. Presents more than 1,000 Netter illustrations accompanied by photos of physical examination techniques, radiographs, and other imaging techniques—including CT and MRI—that equip you with a rich visual understanding of sports medicine. Features a bulleted text format for quick-read guidance. Organizes information by specific types of injuries as well as different types of sports for an easy-to-access reference. Discusses traditional along with less common sports for comprehensive coverage that is up to date. Includes a section that examines considerations for specific athlete populations, including children, women, the senior athlete and the physically challenged, to help you meet their special needs. Presents the cross-disciplinary contributions of primary care physicians, athletic trainers, physical therapists, dentists, orthopaedic surgeons, and others, who provide a well-rounded perspective on the subject. Combines current, evidence-based information with expert clinical guidance for a high-yield reference.
This book will give you a practical overview of several methods and approaches for designing mobile technologies and conducting mobile user research, including how to understand behavior and evaluate how such technologies are being (or may be) used out in the world. Each chapter includes case studies from our own work and highlights advantages, limitations, and very practical steps that should be taken to increase the validity of the studies you conduct and the data you collect. This book is intended as a practical guide for conducting mobile research focused on the user and their experience. We hope that the depth and breadth of case studies presented, as well as specific best practices, will help you to design the best technologies possible and choose appropriate methods to gather ethical, reliable, and generalizable data to explore the use of mobile technologies out in the world.
Why do the vast majority of heroin users live in cities? In his provocative history of heroin in the United States, Eric C. Schneider explains what is distinctively urban about this undisputed king of underworld drugs. During the twentieth century, New York City was the nation's heroin capital—over half of all known addicts lived there, and underworld bosses like Vito Genovese, Nicky Barnes, and Frank Lucas used their international networks to import and distribute the drug to cities throughout the country, generating vast sums of capital in return. Schneider uncovers how New York, as the principal distribution hub, organized the global trade in heroin and sustained the subcultures that supported its use. Through interviews with former junkies and clinic workers and in-depth archival research, Schneider also chronicles the dramatically shifting demographic profile of heroin users. Originally popular among working-class whites in the 1920s, heroin became associated with jazz musicians and Beat writers in the 1940s. Musician Red Rodney called heroin the trademark of the bebop generation. "It was the thing that gave us membership in a unique club," he proclaimed. Smack takes readers through the typical haunts of heroin users—52nd Street jazz clubs, Times Square cafeterias, Chicago's South Side street corners—to explain how young people were initiated into the drug culture. Smack recounts the explosion of heroin use among middle-class young people in the 1960s and 1970s. It became the drug of choice among a wide swath of youth, from hippies in Haight-Ashbury and soldiers in Vietnam to punks on the Lower East Side. Panics over the drug led to the passage of increasingly severe legislation that entrapped heroin users in the criminal justice system without addressing the issues that led to its use in the first place. The book ends with a meditation on the evolution of the war on drugs and addresses why efforts to solve the drug problem must go beyond eliminating supply.
Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative update on our current knowledge of mitochondrial medicine, this text draws together world authorities from various fields to present general therapeutic strategies, as well as the treatments presently available in different specialties - thus making it essential reading for clinicians involved with the management of patients with mitochondrial diseases. A unique work, this text covers a range of specialties, including cardiology, ophthalmology, otology, nephrology, gastroenterology, hematology-oncology, and reproductive medicine, and does not focus exclusively on the more commonly known neurologic conditions. An accessible, user-friendly text, it also presents translational concepts of mitochondrial biogenesis and genetics in vignettes related to specific questions raised by the disease under discussion, rather than concentrating on basic science, which can often intimidate clinicians. This pioneering work is primarily directed to a clinical audience who are interested in the diverse and diagnostically challenging clinical presentations of mitochondrial diseases and their pathophysiology.
Drug Delivery Devices and Therapeutic Systems examines the current technology and innovations moving drug delivery systems (DDS) forward. The book provides an overview on the therapeutic use of drug delivery devices, including design, applications, and a description of the design of each device. While other books focus on the therapy, the primary emphasis in this book is on current technologies for DDS applications, including microfluidics, nanotechnology, biodegradable hydrogel and microneedles, with a special emphasis on wearable DDS. As part of the Developments in Biomedical Engineering and Bioelectronics series, this book is written by experts in the field and informed with information directly from manufacturers. Pharmaceutical scientists, medical researchers, biomedical engineers and clinical professionals will find this an essential reference. Provides essential information on the most recent drug delivery systems available Explains current technology and its applications to drug delivery Contains contributions from biomedical engineers, pharmaceutical scientists and manufacturers
Assessing the formation process of the International Criminal Court (ICC), this study provides a fuller and richer understanding of this institution. It does so by adopting three analytical approaches: neoliberal institutionalism, regime theory and global governance. Examining the implications of the ICC, the volume draws conclusions about the changing nature of world politics in terms of conflict management, authority, governance and actor relevance. It is highly suitable for courses and research in humanitarian and international law, international relations theory, globalization, global governance and regime formation.
Analog circuit design is often the bottleneck when designing mixed analog-digital systems. A Top-Down, Constraint-Driven Design Methodology for Analog Integrated Circuits presents a new methodology based on a top-down, constraint-driven design paradigm that provides a solution to this problem. This methodology has two principal advantages: (1) it provides a high probability for the first silicon which meets all specifications, and (2) it shortens the design cycle. A Top-Down, Constraint-Driven Design Methodology for Analog Integrated Circuits is part of an ongoing research effort at the University of California at Berkeley in the Electrical Engineering and Computer Sciences Department. Many faculty and students, past and present, are working on this design methodology and its supporting tools. The principal goals are: (1) developing the design methodology, (2) developing and applying new tools, and (3) `proving' the methodology by undertaking `industrial strength' design examples. The work presented here is neither a beginning nor an end in the development of a complete top-down, constraint-driven design methodology, but rather a step in its development. This work is divided into three parts. Chapter 2 presents the design methodology along with foundation material. Chapters 3-8 describe supporting concepts for the methodology, from behavioral simulation and modeling to circuit module generators. Finally, Chapters 9-11 illustrate the methodology in detail by presenting the entire design cycle through three large-scale examples. These include the design of a current source D/A converter, a Sigma-Delta A/D converter, and a video driver system. Chapter 12 presents conclusions and current research topics. A Top-Down, Constraint-Driven Design Methodology for Analog Integrated Circuits will be of interest to analog and mixed-signal designers as well as CAD tool developers.
Imaging in Rheumatology: A Clinical Approach is ideal for radiologists and rheumatologists—as well as orthopedic surgeons and others interested in applying imaging to rheumatologic diseases—and stresses conventional radiography as the most effective imaging assessment technique to help diagnose various diseases and conditions. Greenspan and Gershwin—a radiologist and rheumatologist, respectively—focus on practical, everyday use, so you can apply knowledge you learn in any clinical setting.
Few American presidents have exercised their constitutional authority as commander in chief with more determination than Franklin D. Roosevelt. He intervened in military operations more often and to better effect than his contemporaries Churchill and Stalin, and maneuvered events so that the Grand Alliance was directed from Washington. In this expansive history, Eric Larrabee examines the extent and importance of FDR's wartime leadership through his key military leaders—Marshall, King, Arnold, MacArthur, Vandergrift, Nimitz, Eisenhower, Stilwell, and LeMay. Devoting a chapter to each man, the author studies Roosevelt's impact on their personalities, their battles (sometimes with each other), and the consequences of their decisions. He also addresses such critical subjects as Roosevelt's responsibility for the war and how well it achieved his goals. First published in 1987, this comprehensive portrait of the titans of the American military effort in World War II is available in a new paperback edition for the first time in sixteen years.
Learn how to teach like a pro and have fun, too! The more you know about the brains of your students, the better you can be at your profession. Brain-based teaching gives you the tools to boost cognitive functioning, decrease discipline issues, increase graduation rates, and foster the joy of learning. This innovative, new edition of the bestselling Brain-Based Learning by Eric Jensen and master teacher and trainer Liesl McConchie provides an up-to-date, evidence-based learning approach that reveals how the brain naturally learns best in school. Based on findings from neuroscience, biology, and psychology, you will find: In-depth, relevant insights about the impact of relationships, the senses, movement, and emotions on learning Savvy strategies for creating a high-quality learning environment, complete with strategies for self-care Teaching tools to motivate struggling students and help them succeed that can be implemented immediately This rejuvenated classic with its easy-to-use format remains the guide to transforming your classroom into an academic, social, and emotional success story.
Pain management is an essential part of clinical practice for all healthcare providers from trainees, physician assistants and nurse practitioners through to practising physicians. Problem-Based Pain Management is a collaboration between experts in anesthesiology, geriatric medicine, neurology, psychiatry and rehabilitation which presents a multidisciplinary management strategy. Over 60 chapters follow a standard, easy-to-read, quick access format on: clinical presentation, signs and symptoms, lab tests, imaging studies, differential diagnosis, pharmacotherapy, non-pharmacologic approach, interventional procedure, follow-up and prognosis. The broad spectrum of topics include headache, neck and back pain, bursitis, phantom limb pain, sickle cell disease and palliative care. Unlike other large, cumbersome texts currently available, this book serves as a quick, concise and pertinent reference in the diagnosis and management of common pain syndromes.
Over the past half century, reverse osmosis (RO) has grown from a nascent niche technology into the most versatile and effective desalination and advanced water treatment technology available. However, there remain certain challenges for improving the cost-effectiveness and sustainability of RO desalination plants in various applications. In low-pressure RO applications, both capital (CAPEX) and operating (OPEX) costs are largely influenced by product water recovery, which is typically limited by mineral scale formation. In seawater applications, recovery tends to be limited by the salinity limits on brine discharge and cost is dominated by energy demand. The combination of water scarcity and sustainability imperatives, in many locations, is driving system designs towards minimal and zero liquid discharge (M/ZLD) for inland brackish water, municipal and industrial wastewaters, and even seawater desalination. Herein, we review the basic principles of RO processes, the state-of-the-art for RO membranes, modules and system designs as well as methods for concentrating and treating brines to achieve MLD/ZLD, resource recovery and renewable energy powered desalination systems. Throughout, we provide examples of installations employing conventional and some novel approaches towards high recovery RO in a range of applications from brackish groundwater desalination to oil and gas produced water treatment and seawater desalination.
A Readable, Updated Introduction to Textual Criticism This accessibly written, practical introduction to Old Testament textual criticism helps students understand the discipline and begin thinking through complex issues for themselves. The authors combine proven expertise in the classroom with cutting-edge work in Hebrew textual studies. This successful classic (nearly 25,000 copies sold) has been thoroughly expanded and updated to account for the many changes in the field over the past twenty years. It includes examples, illustrations, an updated bibliography, and a textual commentary on the book of Ruth.
Edited by past presidents of the American Medical Society for Sports Medicine, Netter’s Sports Medicine, 2nd Edition, is a superbly illustrated, go-to sports medicine resource for the outpatient office, the training room, on the sideline, and for certification preparation. Designed for quick reference, this interdisciplinary reference by Drs. Christopher Madden, Margot Putukian, Eric McCarty, and Craig Young, is organized by both topic and sport, so you can find what you need quickly. Whether you are a primary care physician managing a common or unique musculoskeletal injury in an ambulatory setting ... an orthopaedic surgeon gaining insight about a medical or psychological problem foreign to the cast or operating room ... an athletic trainer figuring out a diagnosis in the training room ... or a physical therapist pursuing further in-depth sports medicine knowledge, this reference gives you the guidance you need to keep athletes and other active patients at the top of their game. More than 1,000 superb Netter graphics, tables, figures, pictures, diagnostic images, and other medical artwork highlight the easy-to-read, bulleted text. Ideal for the sports clinician, team physician, and any health care professionals who provide care to athletes and active individuals. New chapters on travel considerations for the athlete, EKG interpretation, cardiac disease, diagnostic imaging and ultrasound, injury prevention protocols, equestrian sports and rodeo medicine, mixed martial arts, and many more. Up-to-date coverage of nutritional supplements, eating disorders, sports and pharmacology for chronic conditions and behavioral medicine, and extreme and adventure sports.
Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: RNA Viruses, Seventh Edition covers the latest information on RNA viruses, how they cause disease, how they can cause epidemics and pandemics, new therapeutics and vaccine approaches, as provided in new or extensively revised chapters that reflect these advances in this dynamic field. Bundled with the eBook, which will be updated regularly as new information about each virus is available, this text serves as the authoritative, up-to-date reference book for virologists, infectious disease specialists, microbiologists, and physicians, as well as medical students pursuing a career in infectious diseases.
Little magazines made modernism. These unconventional, noncommercial publications may have brought writers such as James Joyce, T. S. Eliot, Ezra Pound, Marianne Moore, Mina Loy, and Wallace Stevens to the world but, as Eric Bulson shows in Little Magazine, World Form, their reach and importance extended far beyond Europe and the United States. By investigating the global and transnational itineraries of the little-magazine form, Bulson uncovers a worldwide network that influenced the development of literature and criticism in Africa, the West Indies, the Pacific Rim, and South America. In addition to identifying how these circulations and exchanges worked, Bulson also addresses equally formative moments of disconnection and immobility. British and American writers who fled to Europe to escape Anglo-American provincialism, refugees from fascism, wandering surrealists, and displaced communists all contributed to the proliferation of print. Yet the little magazine was equally crucial to literary production and consumption in the postcolonial world, where it helped connect newly independent African nations. Bulson concludes with reflections on the digitization of these defunct little magazines and what it means for our ongoing desire to understand modernism's global dimensions in the past and its digital afterlife.
This book covers some of the most serious mental health conditions that top the global disease burden and affect 3% of the general population. However, most research on psychotic disorders is undertaken in the West, and few studies have been systematically carried out in Asia despite global interest in regional differences. This work offers a unique and coherent account of these disorders and their treatment in Hong Kong over the last thirty years. Chen and his research programme’s pioneering work has ranged from the impact of early intervention on outcomes and relapse prevention, to the renaming of psychosis to reduce stigma. The studies have contributed to wider international debates on the optimal management of the condition. Their investigations in semantics and cognition, as well as cognition-enhancing exercise interventions, have provided novel insights into deficits encountered in psychotic disorders and how they might be ameliorated. The research has also explored subjective experiences of psychosis and elicited unique perspectives in patients of Asian origin. Each topic is divided into three sections: a global background of the challenges encountered; research findings from Hong Kong; and reflections that place the data in scientific and clinical contexts and offer future directions. “This book contains important research into specific problems facing persons with psychosis and schizophrenia in Hong Kong, arising from environment factors, stigma, and treatment shortfalls. Its insights would help “overcome barriers to facilitate mental health work”, which is how Professor Eric Chen describes the work of the Advisory Committee on Mental Health, and what he has admirably devoted himself to do over the years.” —Wong Yan-Lung SC, chairman, Advisory Committee on Mental Health, Hong Kong, 2017–2023 ‘This learned and comprehensive opus about schizophrenia, its causes, course, and outcomes reaches far beyond its regional scope and presents the best of the world’s current knowledge about schizophrenia as well as the significant contribution to it made by the authors working in Hong Kong.’ —Norman Sartorius, MD, PhD, FRCPsych, president, Association of the Improvement of Mental Health Programs, Geneva
The new edition of this definitive textbook reflects the continuing reintegration of psychiatry into the mainstream of biomedical science. The research tools that are transforming other branches of medicine - epidemiology, genetics, molecular biology, imaging, and medicinal chemistry - are also transforming psychiatry. The field stands poised to make dramatic advances in defining disease pathogenesis, developing diagnostic methods capable of identifying specific and valid disease entities, discovering novel and more effective treatments, and ultimately preventing psychiatric disorders. The Neurobiology of Mental Illness is written by world-renowned experts in basic neuroscience and the pathophysiology and treatment of psychiatric disorders. It begins with a succint overview of the basic neurosciences followed by and evaluation of the tools that are available for the study of mental disorders in humans. The core of the book is a series of consistently organized sections on the major psychiatric disorders that cover their diagnostic classification, molecular genetics, functional neuroanatomy, neurochemistry and pharmacology, neuroimaging, and principles of pharmacotherapy. Chapters are written in a clear style that is easily accessible to practicing psychiatrists, and yet they are detailed enough to interest researchers and academics. For this second edition, every section has been thoroughly updated, and 13 new chapters have been added in areas where significant advances have been made, including functional genomics and animal models of illness; epidemiology; cognitive neuroscience; postmortem investigation of human brain; drug discovery methods for psychiatric disorders; the neurobiology of schizophrenia; animal models of anxiety disorders; neuroimaging studies of anxiety disorders; developmental neurobiology and childhood onset of psychiatric disorders; the neurobiology of mental retardation; the interface between neurological and psychiatric disorders; the neurobiology of circadian rhythms; and the neurobiology of sleep disorders. Both as a textbook and a reference work, Neurobiology of Mental Illness represents a uniquely valuable resource for psychiatrists, neuroscientists, and their students or trainees.
Li-Co-Mn-Ni oxides have been of extreme interest as potential positive electrode materials for next generation Li-ion batteries. Though many promising materials have been discovered and studied extensively, much debate remains in the literature about the structures of these materials. There is no consensus as to whether the lithium-rich layered materials are single-phase or form a layered-layered composite on the few nanometer length-scales. Much of this debate came about because no phase diagrams existed to describe these systems under the synthesis conditions used to make electrode materials. Detailed in this thesis are the complete Li-Co-Mn-O and Li-Mn-Ni-O phase diagrams generated by way of the combinatorial synthesis of mg-scale samples at over five hundred compositions characterized with X-ray diffraction. Selected bulk samples were used to confirm that the findings are relevant to synthesis conditions used commercially. The results help resolve a number of points of confusion and contradiction in the literature. Amongst other important findings, the compositions and synthesis conditions giving rise to layered-layered nano-composites are presented and electrochemical results are used to show how better electrode materials can be achieved by making samples in the single phase-layered regions.
Thank you for visiting our website. Would you like to provide feedback on how we could improve your experience?
This site does not use any third party cookies with one exception — it uses cookies from Google to deliver its services and to analyze traffic.Learn More.