For over a century, New Zealand has built its economy through a series of commodity-based booms—from wood and wool to beef and butter. Now the country faces new challenges. In a world where value is increasingly rooted in capital- and technology-intensive industries, can countries dependent on agriculture really sustain its high living standards by growing crops? This book takes readers out on to farms, orchards, and vineyards, and inside the offices and factories of processors and exporters, to show how innovative New Zealanders are answering these challenges. From Icebreaker clothing to Mr Apple fruit exports, innovative companies are creating high-value, unique products, rooted in particular places, and making pathways to the niche markets where they can realize that value.
The field of management research is commonly regarded as or aspires to be a science discipline. As such, management researchers face similar methodological problems as their counterparts in other science disciplines. There are at least two ways that philosophy is connected with management research: ontological and epistemological. Despite an increasing number of scattered philosophy-based discussions of research methodology, there has not been a book that provides a systematic and more comprehensive treatment of the subject. This book addresses this gap in the market and provides new ideas and arguments for guiding management researchers.
The names have been changed to protect the guilty in this otherwise-authentic Prohibition memoir. Published under a pseudonym in 1928, the reminiscences offer an inside look at bootlegging-related corruption and violence.
This textbook is aimed at undergraduate and diploma students across a wide range of the social sciences, with particular reference to those preparing for or involved in careers in social and public administration. It provides, in compact form, the story of social provision from medieval times to the present day, systematically examining major themes of: the relief of poverty and social care; healthcare and housing; crime and policing; and education. With the rise of the Welfare State, and its current questioning as the chief focus, the book sets out to analyze how the state has responded to the social problems that have beset it. Consideration is given to comparative elements in Europe, North America and elsewhere, together with specific reference to issues of race, ethnicity and gender. A specially prepared glossary completes what is a review and description of the growth and present disposition of the full range of social and public services in Britain.
The history, development, and future directions of evaluation in various European and Asian countries are described and examined. Chapter topics include international organizations or associations that influence this global direction."--Business Horizon Evaluation of public policy has changed considerably in the past decade. This is especially true in Europe, where evaluation is now an institutional part of public sector governance, but it is also characteristic of other parts of the world. The International Atlas of Evaluation describes individual country as well as global trends and developments in the application and impact of evaluation. It also explains underlying forces affecting the contour of evaluation in different national contexts and their consequences for the diffusion of evaluation. The International Atlas of Evaluation describes and examines the history development and future directions of evaluation in twenty-two countries: Australia, Canada, China, Denmark, Finland, France, Germany, Switzerland, Ireland, Israel, Italy, Japan, Korea, the Netherlands, New Zealand, Norway, Spain, Sweden, Switzerland, Zimbabwe, the United Kingdom, and the United States. It includes chapters on international organizations or associations that heavily influence the global direction of evaluation-the European Union, the World Bank, and Development Assistance Evaluation. The volume includes a historical overview of supply and demand in relation to evaluation; shifts in institutional settings; university programs and other sources of training; descriptions of its applications in the executive and legislative branches of government; and observations on the status and future of national systems of evaluation. The Atlas explores whether those countries where evaluation "took off" some years ago are expanding its use, or whether its development has stabilized or even decreased. It explores factors supporting the development of evaluation in a number of developing countries. This volume in the Comparative Policy Analysis series is an essential tool for policy makers, government officials, and scholars interested in the contemporary status of evaluation. Jan-Eric Furubo is head of the Secretariat for Strategic Analyses in the National Audit Office in Sweden. Ray C. Rist is a senior evaluation officer with the Operations Evaluation Department of the World Bank. He has held senior positions in both the legislative and executive branches of the United States government as well as teaching positions at Cornell University, The John Hopkins University, and George Washington University. Rolf Sandahl is an expert in evaluation at the National Financial Management Authority in Sweden, and author of many books and articles in the area of policy instruments, results analysis, and management by results.
With surprising tales of vicious mutineers, imperial riches, and high-seas intrigue, Black Flags, Blue Waters is “rumbustious enough for the adventure-hungry” (Peter Lewis, San Francisco Chronicle). Set against the backdrop of the Age of Exploration, Black Flags, Blue Waters reveals the surprising history of American piracy’s “Golden Age” - spanning the late 1600s through the early 1700s - when lawless pirates plied the coastal waters of North America and beyond. “Deftly blending scholarship and drama” (Richard Zacks), best-selling author Eric Jay Dolin illustrates how American colonists at first supported these outrageous pirates in an early display of solidarity against the Crown, and then violently opposed them. Through engrossing episodes of roguish glamour and extreme brutality, Dolin depicts the star pirates of this period, among them the towering Blackbeard, the ill-fated Captain Kidd, and sadistic Edward Low, who delighted in torturing his prey. Upending popular misconceptions and cartoonish stereotypes, Black Flags, Blue Waters is a “tour de force history” (Michael Pierce, Midwestern Rewind) of the seafaring outlaws whose raids reflect the precarious nature of American colonial life.
The familiar industrialisation of northern England and less familiar de-industrialisation of the south are shown to have depended on a common process. Neither rise nor decline resulted from differences in natural resource endowments, since they began before the use of coal and steam in manufacturing. Instead, political certainty, competitive ideology and Enlightenment optimism encouraged investment in transport and communications. This integrated the national market, intensifying competition between regions and altering economic distributions. Despite a dysfunctional landed system, agricultural innovation meant that the south's comparative advantage shifted towards the farm sector. Meanwhile its manufactures slowly declined. Once industry clustered in the less-benign northern environment, technological changes in manufacturing accumulated there. This book portrays the Industrial Revolution as deriving from economic competition within unique political arrangements.
This 1995 book contributes to both modern German history and to the sociological understanding of crime in modern industrial and urban societies. Its central argument is that cities, in themselves, do not cause crime. It focuses on the problems of crime and criminal justice during Germany's period of most rapid urban and industrial growth - a period when Germany also rose to world power status. From 1871 to 1914, German cities, despite massive growth, socialist agitation and non-ethnic German immigration, were not particularly infested with crime. Yet the conservative political and religious elites constantly railed against the immoral nature of the city and the German governmental authorities, police, and court officials often overreacted against city populations. In so doing, they helped to set Germany on a dangerous authoritarian course.
The Pentecostal mission in Palestine is a virtually unknown episode in the history of Pentecostalism. Its story begins in 1906 at the Azusa Street Revival, from which missionaries were sent to Palestine. In its first thirty years, the Pentecostal mission in Palestine gained a foothold in Jerusalem and expanded its reach into Jordan, Syria, and Iran. It was severely tested and lost traction during the tumultuous period of the Arab Revolts, World War II, and the Partition Crisis. With the catastrophic war of 1948, the Pentecostal missionaries fled as their Arab clients were swept away in the Palestinian Diaspora. After 1948, a valiant attempt was made to revive the mission, but only with relative success. Although the Pentecostal missionaries failed in their objective of converting Jews and Muslims, they were eyewitnesses of the formative events of the Arab-Israeli conflict. Newberg argues that the Pentecostal missionaries functioned as brokers of Pentecostal Zionism. He offers a postcolonial assessment of the Pentecostal missionaries, crediting them for advocating philosemitism, yet bringing them up short for disregarding the civil rights of Palestinian Arabs, espousing Islamophobia, and contributing to the forces working against peace in the Holy Land.
Over the past forty years, numerous theoretical advances have been made. From Ayres’ and Braithwaite’s ground breaking work on ‘responsive regulation’, we have seen models of ‘smart regulation’, ‘regulatory governance’ and ‘regulatory capitalism’ emerge to capture the growing prevalence and importance of regulation in modern liberal Western capitalist societies. Important advances also have been made in the practice of regulation, with regulators evolving from traditional enforcement focussed ‘command and control’ models to being ‘modern regulators’ with a suite of diverse and innovative regulatory tools at their disposal. The book presents and critically examines these theoretical and practical developments from the perspective of governments who design regulations, and the regulators that deploy them. In doing so, the book examines the various forces and interests that influence and shape the regulatory endeavour, and the practical challenges facing governments and regulators when deciding whether and how to regulate. This volume is a study of regulation in context: in the context of the public policy it is designed to deliver; the law that enables, shapes and holds it to account; and the evolving societal and institutional frameworks within which it takes place. Aimed to provide innovative cross-disciplinary conceptual frameworks that regulators, regulatees, those whom regulation is intended to benefit, and academics, might employ to better understand and undertake the regulatory endeavour. This will be of great interest to researchers, educators, advanced students and practitioners working in the fields of political science, public management and administration, and public policy. .
Rethinking Culture in Health Communication An interdisciplinary overview of health communication using a cultural lens—uniquely focused on social interactions in health contexts Patients, health professionals, and policymakers embody cultural constructs that impact healthcare processes. Rethinking Culture in Health Communication explores the ways in which culture influences healthcare, introducing new approaches to understanding social relationships and health policies as a dynamic process involving cultural values, expectations, motivations, and behavioral patterns. This innovative textbook integrates theories and practices in health communication, public health, and medicine to help students relate fundamental concepts to their personal experiences and develop an awareness of how all individuals and groups are shaped by culture. The authors present a foundational framework explaining how cultures can be understood from four perspectives—Magic Consciousness, Mythic Connection, Perspectival Thinking, and Integral Fusion—to examine existing theories, social norms, and clinical practices in health-related contexts. Detailed yet accessible chapters discuss culture and health behaviors, interpersonal communication, minority health and healthcare delivery, cultural consciousness, social interactions, sociopolitical structure, and more. The text features examples of how culture can create challenges in access, process, and outcomes of healthcare services and includes scenarios in which individuals and institutions hold different or incompatible ethical views. The text also illustrates how cultural perspectives can shape the theoretical concepts emerged in caregiver-patient communication, provider-patient interactions, social policies, public health interventions, and other real-life settings. Written by two leading health communication scholars, this textbook: Highlights the sociocultural, interprofessional, clinical, and ethical aspects of health communication Explores the intersections of social relationships, cultural tendencies, and health theories and behaviors Examines the various forms, functions, and meanings of health, illness, and healthcare in a range of cultural contexts Discusses how cultural elements in social interactions are essential to successful health interventions Includes foundational overviews of health communication and of culture in health-related fields Discusses culture in health administration, moral values in social policies, and ethics in medical development Incorporates various aspects and impacts of the COVID-19 pandemic as a cultural phenomenon through the lens of health communication Rethinking Culture in Health Communication is an ideal textbook for courses in health communication, particularly those focused on interpersonal communication, as well as in cross-cultural communication, cultural phenomenology, medical sociology, social work, public health, and other health-related fields.
First Published in 2005. This book argues that the agricultural revolution took place in England in the sixteenth and seventeenth centuries and not in the eighteenth and nineteenth.
Bio-Guided Music Therapy explores the clinical integration of music and biofeedback, providing the practitioner with a rationale, historical context and detailed step-by-step instructions for implementing real-time physiological data driven music therapy. This practical guide introduces the fundamental principles of biofeedback and explores the use of music therapy interventions in the context of achieving skills in self-regulation of physiological response. The book looks at the primary modalities of biofeedback, in conjunction with the assignment of digitally sampled musical voices to specific body functions. Additional music therapy interventions discussed include guided imagery to music, toning, mantra meditation, drumming and improvisation. We see how physiological data taken in the moment and combined with music therapy techniques, may be successfully applied to the treatment of stress, anxiety, high blood pressure, chronic pain, dementia, migraine, ADHD and addictions. Instructive and accessible, this book will prove an essential resource for students and practitioners of music therapy, biofeedback practitioners, social workers, psychologists and healing arts professionals.
Evaluation has come of age. Today most social and political observers would have difficulty imagining a society where evaluation is not a fixture of daily life, from individual programs to local authorities to parliamentary committees. While university researchers, grant makers and public servants may think there are too many types of evaluation, rankings and reviews, evaluation is nonetheless viewed positively by the public. It is perceived as a tool for improvement and evaluators are seen as dedicated to using their knowledge for the benefit of society. The book examines the degree to which evaluators seek power for their own interests. This perspective is based on a simple assumption: If you are in possession of an asset that can give you power, why not use it for your own interests? Can we really trust evaluation to be a force for the good? To what degree can we talk about self-interest in evaluation, and is this self-interest something that contradicts other interests such as "the benefit of society?" Such questions and others are addressed in this brilliant, innovative, international collection of pioneering contributions.
1. Metaphors and Logic Metaphors are among the most vigorous offspring of the creative mind; but their vitality springs from the fact that they are logical organisms in the ecology of l- guage. I aim to use logical techniques to analyze the meanings of metaphors. My goal here is to show how contemporary formal semantics can be extended to handle metaphorical utterances. What distinguishes this work is that it focuses intensely on the logical aspects of metaphors. I stress the role of logic in the generation and int- pretation of metaphors. While I don't presuppose any formal training in logic, some familiarity with philosophical logic (the propositional calculus and the predicate c- culus) is helpful. Since my theory makes great use of the notion of structure, I refer to it as the structural theory of m etaphor (STM). STM is a semant ic theory of m etaphor : if STM is correct, then metaphors are cognitively meaningful and are n- trivially logically linked with truth. I aim to extend possible worlds semantics to handle metaphors. I'll argue that some sentences in natural languages like English have multiple meanings: "Juliet is the sun" has (at least) two meanings: the literal meaning "(Juliet is the sunkIT" and the metaphorical meaning "(Juliet is the sun)MET". Each meaning is a function from (possible) worlds to truth-values. I deny that these functions are identical; I deny that the metaphorical function is necessarily false or necessarily true.
This book deals sequentially with major impediments to economic growth and their slow dissolution. It is original and quite different from standard economic history, which has always sought for one prime mover of the industrial revolution after another. These supposed positive forces are usually depicted as novel and little reference is made to inertia. Instead the barriers dealt with here run, in the first section, from early misallocations of resources to nineteenth-century reforms which of their nature indicate the problems to be overcome. The second section deals with more physical impediments and shocks, such as floods and settlement fires. These too are ignored in ordinary treatments, which this book will supplement or even replace. It will be of interest to academic economic historians and practitioners of neighbouring subjects such as economists, historians, historical geographers, and of course their students.
This reference brings together all aspects of renal cell carcinoma, and provides a basis for understanding the disease's origin, progression and responses to immunotherapy.;Examining the current status of cytokine, cell-based and chemotherapeutic methods of treatment, this book: discusses the clinical presentation of advanced renal carcinoma and its therapeutic challenges; reviews prognostic factors and the management of renal cell carcinoma occurring with von Hippel-Landau syndrome; summarizes efforts to identify the tumour suppressor gene deleted from chromosome 3 in most renal cell carcinomas; explicates the role of oncogenes in the progression of renal cell cancer and the molecular correlates of responses to interferon-alpha treatment; details the latest laboratory efforts to establish gene therapy for tumour treatment by transfection of cytokine genes in murine model systems; focuses on biologic response modifier therapy in humans, including cell-mediated immune responses and adoptive immunotherapy; presents preclinical and clinical studies of interleukin-2 alone, in combination with othe cytokines, and with chemothrapeutic agents; and addresses studies on the tumour necrosis factor and low- and high-dose interferon-alpha.
The ideal text for students in advanced cell biology courses, Lewin’s CELLS, Third Edition continues to offer a comprehensive, rigorous overview of the structure, organization, growth, regulation, movements, and interactions of cells, with an emphasis on eukaryotic cells. The text provides students with a solid grounding in the concepts and mechanisms underlying cell structure and function, and will leave them with a firm foundation in cell biology as well as a “big picture” view of the world of the cell. Revised and updated to reflect the most recent research in cell biology, Lewin’s CELLS, Third Edition includes expanded chapters on Nuclear Structure and Transport, Chromatin and Chromosomes, Apoptosis, Principles of Cell Signaling, The Extracellular Matrix and Cell Adhesion, Plant Cell Biology, and more. All-new design features and a chapter-by-chapter emphasis on key concepts enhance pedagogy and emphasize retention and application of new skills.
As developers know, the beauty of XML is that it is extensible, even to the point that you can invent new elements and attributes as you write XML documents. Then, however, you need to define your changes so that applications will be able to make sense of them and this is where XML schema languages come into play. RELAX NG (pronounced relaxing), the Regular Language Description for XML Core--New Generation is quickly gaining momentum as an alternative to other schema languages. Designed to solve a variety of common problems raised in the creation and sharing of XML vocabularies, RELAX NG is less complex than The W3C's XML Schema Recommendation and much more powerful and flexible than DTDs. RELAX NG is a grammar-based schema language that's both easy to learn for schema creators and easy to implement for software developers In RELAX NG, developers are introduced to this unique language and will learn a no-nonsense method for creating XML schemas. This book offers a clear-cut explanation of RELAX NG that enables intermediate and advanced XML developers to focus on XML document structures and content rather than battle the intricacies of yet another convoluted standard. RELAX NG covers the following topics in depth: Introduction to RELAX NG Building RELAX NG schemas using XML syntax Building RELAX NG schemas using compact syntax, an alternative non-XML syntax Flattening schemas to limit depth and provide reusability Using external datatype libraries with RELAX NG W3C XML Schema regular expressions Writing extensible schemas Annotating schemas Generating schemas form different sources Determinism and datatype assignment and much more. If you're looking for a schema language that's easy to use and won't leave you in a labyrinth of obscure limitations, RELAX NG is the language you should be using. And only O'Reilly's RELAX NG gives you the straightforward information and everything else you'll need to take advantage of this powerful and intelligible language.
What could be better than diving into cool water on a hot day? In this enormously enjoyable and informative history of swimming, Eric Chaline sums up this most summery of moments with one phrase: pleasure beckons at the water’s edge. Strokes of Genius traces the history of swimming from the first civilizations to its current worldwide popularity as a sport, fitness pastime, and leisure activity. Chaline explores swimming’s role in ritual, early trade and manufacturing, warfare, and medicine, before describing its transformation in the early modern period into a leisure activity and a competitive sport—the necessary precursors that have made it the most common physical pastime in the developed world. The book celebrates the physicality and sensuality of swimming—attributes that Chaline argues could have contributed to the evolution of the human species. Swimming, like other disciplines that use repetitive movements to train the body and quiet the mind, is also a means of spiritual awakening—a personal journey of discovery. Swimming has attained the status of a cultural marker, denoting eroticism, leisure, endurance, adventure, exploration, and excellence. Strokes of Genius shows that there is not a single story of human swimming, but many currents that merge, diverge, and remerge. Chaline argues that swimming will become particularly important as we look toward a warmer future in which our survival may depend on our ability to adapt to life in an aquatic world.
This book focuses on developing a systematic approach to understanding the transformations in Africa's public sector social media landscape. Looking at the use of social media from the African public sector perspective, the authors present a comprehensive understanding of social media practices and how these could be integrated into African public sector institutions’ operational activities in order to deliver greater value for African citizens and consumers of public goods and services. Chapters explore how social media in Africa differs from traditional media use, their application in the public sector, objectives for government using social media, and how social media plays an interactive role in e-government services. Providings practical guidance on the use of social media in Africa’s public sector and governmental spaces, the book also serves as a teaching text in governance and public sector communication efforts within the African context for both undergraduate and graduate programmes.
This open access book examines the methodological complications of using complexity science concepts within the social science domain. The opening chapters take the reader on a tour through the development of simulation methodologies in the fields of artificial life and population biology, then demonstrates the growing popularity and relevance of these methods in the social sciences. Following an in-depth analysis of the potential impact of these methods on social science and social theory, the text provides substantive examples of the application of agent-based models in the field of demography. This work offers a unique combination of applied simulation work and substantive, in-depth philosophical analysis, and as such has potential appeal for specialist social scientists, complex systems scientists, and philosophers of science interested in the methodology of simulation and the practice of interdisciplinary computing research.
Land conversion, climate change and species invasions are contributing to the widespread emergence of novel ecosystems, which demand a shift in how we think about traditional approaches to conservation, restoration and environmental management. They are novel because they exist without historical precedents and are self-sustaining. Traditional approaches emphasizing native species and historical continuity are challenged by novel ecosystems that deliver critical ecosystems services or are simply immune to practical restorative efforts. Some fear that, by raising the issue of novel ecosystems, we are simply paving the way for a more laissez-faire attitude to conservation and restoration. Regardless of the range of views and perceptions about novel ecosystems, their existence is becoming ever more obvious and prevalent in today’s rapidly changing world. In this first comprehensive volume to look at the ecological, social, cultural, ethical and policy dimensions of novel ecosystems, the authors argue these altered systems are overdue for careful analysis and that we need to figure out how to intervene in them responsibly. This book brings together researchers from a range of disciplines together with practitioners and policy makers to explore the questions surrounding novel ecosystems. It includes chapters on key concepts and methodologies for deciding when and how to intervene in systems, as well as a rich collection of case studies and perspective pieces. It will be a valuable resource for researchers, managers and policy makers interested in the question of how humanity manages and restores ecosystems in a rapidly changing world. A companion website with additional resources is available at www.wiley.com/go/hobbs/ecosystems
Genomic Control Process explores the biological phenomena around genomic regulatory systems that control and shape animal development processes, and which determine the nature of evolutionary processes that affect body plan. Unifying and simplifying the descriptions of development and evolution by focusing on the causality in these processes, it provides a comprehensive method of considering genomic control across diverse biological processes. This book is essential for graduate researchers in genomics, systems biology and molecular biology seeking to understand deep biological processes which regulate the structure of animals during development. - Covers a vast area of current biological research to produce a genome oriented regulatory bioscience of animal life - Places gene regulation, embryonic and postembryonic development, and evolution of the body plan in a unified conceptual framework - Provides the conceptual keys to interpret a broad developmental and evolutionary landscape with precise experimental illustrations drawn from contemporary literature - Includes a range of material, from developmental phenomenology to quantitative and logic models, from phylogenetics to the molecular biology of gene regulation, from animal models of all kinds to evidence of every relevant type - Demonstrates the causal power of system-level understanding of genomic control process - Conceptually organizes a constellation of complex and diverse biological phenomena - Investigates fundamental developmental control system logic in diverse circumstances and expresses these in conceptual models - Explores mechanistic evolutionary processes, illuminating the evolutionary consequences of developmental control systems as they are encoded in the genome
Aimed at advanced undergraduates, postgraduates and researchers, this important textbook provides a detailed description of the structure and mechanisms of phosphoinositide 3-kinase (PI3Ks) signalling of all classes, with focus on the cellular context of PI3K activity, including its relevance to normal tissue and diseased states.This book contains a general review chapter detailing the mechanisms of cell proliferation and apoptosis, which are two of the main cellular targets of PI3K signalling. In addition, it provides a detailed description of the role of PI3K on the regulation of FOXO proteins, which are now becoming one of the most closely studied and important proteins in the regulation of cell death, cell proliferation and senescence./a
Donald Langham and Maria Dupré must navigate a rocky road to find a killer when a body is found next to a standing stone. Newlyweds Donald Langham and Maria Dupré have moved to the country. They're excited about starting a new life in the picturesque village of Ingoldby-over-Water – and about meeting their new neighbours. But they’ve barely moved into Yew Tree Cottage when their new neighbour at Standing Stone Manor, Professor Edwin Robertshaw, invites Donald over to discuss some ‘fishy business’. Shortly after, a body is found by the professor’s precious standing stone in the manor grounds. Donald and Maria discover tensions, disputes and resentment raging below the surface of this idyllic village, but can they find out which of the villagers is a cold-blooded killer?
Offering a multifaceted, practical approach to the complex topic of clinical assessment, Practical Guide to the Assessment of Clinical Competence, 3rd Edition, is designed to help medical educators employ better assessment methods, tools, and models directly into their training programs. World-renowned editors and expert contributing authors provide hands-on, authoritative guidance on outcomes-based assessment in clinical education, presenting a well-organized, diverse combination of methods you can implement right away. This thoroughly revised edition is a valuable resource for developing, implementing, and sustaining effective systems for assessing clinical competence in medical school, residency, and fellowship programs. - Helps medical educators and administrators answer complex, ongoing, and critical questions in today's changing medical education system: Is this undergraduate or postgraduate medical student prepared and able to move to the next level of training? To be a competent and trusted physician? - Provides practical suggestions and assessment approaches that can be implemented immediately in your training program, tools that can be used to assess and measure clinical performance, overviews of key educational theories, and strengths and weaknesses of every method. - Covers assessment techniques, frameworks, high-quality assessment of clinical reasoning and procedural competence, psychometrics, and practical approaches to feedback. - Includes expanded coverage of fast-moving areas where concepts now have solid research and data that support practical ways to connect judgments of ability to outcomes—including work-based assessments, clinical competency committees, milestones and entrustable professional assessments (EPAs), and direct observation. - Offers examples of assessment instruments along with suggestions on how you can apply these methods and instruments in your own setting, as well as guidelines that apply across the medical education spectrum. - Includes online access to videos of medical interviewing scenarios and more, downloadable assessment tools, and detailed faculty guidelines. - An eBook version is included with purchase. The eBook allows you to access all of the text, figures, and references, with the ability to search, make notes and highlights, and have content read aloud.
This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.
Over 500 pages of facts, statistics, and records of every match and every player for the Australian national Rugby Union team from the first match in June 1899 up to December 2023.
The new edition of this definitive textbook reflects the continuing reintegration of psychiatry into the mainstream of biomedical science. The research tools that are transforming other branches of medicine - epidemiology, genetics, molecular biology, imaging, and medicinal chemistry - are also transforming psychiatry. The field stands poised to make dramatic advances in defining disease pathogenesis, developing diagnostic methods capable of identifying specific and valid disease entities, discovering novel and more effective treatments, and ultimately preventing psychiatric disorders. The Neurobiology of Mental Illness is written by world-renowned experts in basic neuroscience and the pathophysiology and treatment of psychiatric disorders. It begins with a succint overview of the basic neurosciences followed by and evaluation of the tools that are available for the study of mental disorders in humans. The core of the book is a series of consistently organized sections on the major psychiatric disorders that cover their diagnostic classification, molecular genetics, functional neuroanatomy, neurochemistry and pharmacology, neuroimaging, and principles of pharmacotherapy. Chapters are written in a clear style that is easily accessible to practicing psychiatrists, and yet they are detailed enough to interest researchers and academics. For this second edition, every section has been thoroughly updated, and 13 new chapters have been added in areas where significant advances have been made, including functional genomics and animal models of illness; epidemiology; cognitive neuroscience; postmortem investigation of human brain; drug discovery methods for psychiatric disorders; the neurobiology of schizophrenia; animal models of anxiety disorders; neuroimaging studies of anxiety disorders; developmental neurobiology and childhood onset of psychiatric disorders; the neurobiology of mental retardation; the interface between neurological and psychiatric disorders; the neurobiology of circadian rhythms; and the neurobiology of sleep disorders. Both as a textbook and a reference work, Neurobiology of Mental Illness represents a uniquely valuable resource for psychiatrists, neuroscientists, and their students or trainees.
This book critically assesses Christchurch, New Zealand as an evolving post-earthquake city. It examines the impact of the 2010–13 Canterbury earthquake sequence, employing a chronological structure to consider ‘damage and displacement’, ‘recovery and renewal’ and ‘the city in transition’. It offers a framework for understanding the multiple experiences and realities of post-earthquake recovery. It details how the rebuilding of the city has occurred and examines what has arisen in the context of an unprecedented opportunity to refashion land uses and social experience from the ground up. A recurring tension is observed between the desire and tendency of some to reproduce previous urban orthodoxies and the experimental efforts of others to fashion new cultures of progressive place-making and attention to the more-than-human city. The book offers several lessons for understanding disaster recovery in cities. It illuminates the opportunities disasters create for both the reassertion of the familiar and the emergence of the new; highlights the divergence of lived experience during recovery; and considers the extent to which a post-disaster city is prepared for likely climate futures. The book will be valuable reading for critical disaster researchers as well as geographers, sociologists, urban planners and policy makers interested in disaster recovery.
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