Although thought of as a minor crop, peppers are a major world commodity due to their great versatility. They are used not only as vegetables in their own right but also as flavourings in food products, pharmaceuticals and cosmetics. Aimed at advanced students and growers, this second edition expands upon topics covered in the first, such as the plant's history, genetics, production, diseases and pests, and brings the text up to date with current research and understanding of this genus. New material includes an expansion of marker-assisted breeding to cover the different types of markers available, new directions, and trends in the industry, the loss of germplasm and access to it, and the long term preservation of Capsicum resources worldwide. It is suitable for horticultural researchers, extension workers, academics, breeders, growers, and students.
This book explores the state of California — viewing the state as a holistic political culture that reflects the influence of multiple cultures, ethnic groups, and communities of interest. It starts with a broad historical foundation, and travels through cultural analyses and institutional discussions. The evaluation of specific policy issues affecting the state is an important stop along the way, and the crossroads that bring together the variety of analytic paths. This book is suited for individuals interested in California policy work, and gaining a better understanding of that state's unique political culture.
Factoid Attack: Inherent sadistic streak in dentists confirmed! The electric chair was invented by a dentist, Dr. Alfred Southwick. Not surprising, dentists have been perfecting torture devices for centuries. Factoid Attack: Galaxy at risk! Intelligent life in short supply! In 1961, Astronomer Frank Drake estimated the number of probable intelligent civilizations inhabiting our galaxy. Using conservative numbers, that estimate came to 10,000. Unfortunately, we are not included in that total. Factoid Attack: Colorblind bulls hate all matadors equally! The color of a matador's cape, or muleta, is traditionally red, which is widely believed to irritate the bull. In reality, bulls are colorblind, so it is irrelevant what color cape a matador uses to antagonize them. Shot in the dark, but maybe it's the being stabbed with swords bit that pisses them off. Forget Fringe, Warehouse 13, and The X-Files. In this book, you'll find more weird and wacko truths than in all those combined. From golden poison dart frogs with enough venom to kill ten grown humans to cockroaches that can survive radiation 15 times stronger than what kills people, scary and strange just got scarier—and stranger!
The city of New York is the city of skyscrapers. Every first-time visitor to Manhattan experiences the awe of gazing up at the soaring stone, steel, and glass towers of Wall Street or Midtown, and wonders how those structures came to be built. Manhattan Skyscrapers answers the question by presenting the 75 most significant tall buildings that make up the city's famous skyline. From Louis Sullivan's Bayard-Condict Building of 1898 on Bleeker Street to the Conde Nast tower currently rising above Times Square, Manhattan Skyscrapers lavishly presents over a hundred years of New York's most interesting and important tall buildings. Author Eric P. Nash profiles familiar skyscrapers such as the Woolworth Building, the Empire State Building, the Chrysler Building, the World Trade Towers, the AT&T (now Sony) Building, and the Seagram Building, while also championing several often-overlooked yet significant structures, such as the McGraw- Hill, the Metropolitan Life Insurance, and the Fred F. French Buildings. Nash's writing strikes an elegant balance between history, archi-tectural evaluation, and intelligent guidebook. For each building, Nash identifies the building style, gives the overall profile and image of the building, and discusses its construction; also included are quotes from the buildings' architects and the architectural critics of the time. Each skyscraper is illustrated with full-page color photo-graphs by noted photographer Norman McGrath as well as architectural drawings and plans, archival images of the original interiors, postcards, and other ephemera. Manhattan Skyscrapers is essential reading-or an ideal gift-for anyone interested in the buildings that make New York the ultimate skyscraper city.
When you have questions about C# 8.0 or .NET Core, this best-selling guide has the answers you need. C# is a language of unusual flexibility and breadth, but with its continual growth there’s so much more to learn. In the tradition of the O’Reilly Nutshell guides, this thoroughly updated edition is simply the best one-volume reference to the C# language available today. Organized around concepts and use cases, C# 8.0 in a Nutshell provides intermediate and advanced programmers with a concise map of C# and .NET knowledge that also plumbs significant depths. Get up to speed on C#, from syntax and variables to advanced topics such as pointers, closures, and patterns Dig deep into LINQ with three chapters dedicated to the topic Explore concurrency and asynchrony, advanced threading, and parallel programming Work with .NET features, including regular expressions, networking, serialization, spans, reflection, and cryptography Delve into Roslyn, the modular C# compiler as a service
One of our most important political theorists pulls the philosophical rug out from under modern liberalism, then tries to place it on a more secure footing. We think of modern liberalism as the novel product of a world reinvented on a secular basis after 1945. In The Theology of Liberalism, one of the country’s most important political theorists argues that we could hardly be more wrong. Eric Nelson contends that the tradition of liberal political philosophy founded by John Rawls is, however unwittingly, the product of ancient theological debates about justice and evil. Once we understand this, he suggests, we can recognize the deep incoherence of various forms of liberal political philosophy that have emerged in Rawls’s wake. Nelson starts by noting that today’s liberal political philosophers treat the unequal distribution of social and natural advantages as morally arbitrary. This arbitrariness, they claim, diminishes our moral responsibility for our actions. Some even argue that we are not morally responsible when our own choices and efforts produce inequalities. In defending such views, Nelson writes, modern liberals have implicitly taken up positions in an age-old debate about whether the nature of the created world is consistent with the justice of God. Strikingly, their commitments diverge sharply from those of their proto-liberal predecessors, who rejected the notion of moral arbitrariness in favor of what was called Pelagianism—the view that beings created and judged by a just God must be capable of freedom and merit. Nelson reconstructs this earlier “liberal” position and shows that Rawls’s philosophy derived from his self-conscious repudiation of Pelagianism. In closing, Nelson sketches a way out of the argumentative maze for liberals who wish to emerge with commitments to freedom and equality intact.
Rising stars in Boston's design scene, architects Eric Howeler and J. Meejin Yoon have in a single decade developed a reputation for radical experiments in architectural form. Their design methodology--what they call an "expanded practice"--combines intense research with interdisciplinary experimentation. Howeler and Yoon's sensational, competition-winning lighting entry for the 2004 Athens Olympics exemplifies their fearless approach: without any prior experience in public space interactive design, the firm constructed a luminous, interactive soundscape installation at the base of the Acropolis. White Noise White Light featured a field of semiflexible fiber-optic strands that emitted white light and white noise in response to the movement of pedestrians. The project, an enormous success, enchanted a multitude of visitors who moved amidst the cilia of light. Expanded Practice presents twenty-nine recent projects by this young firm encompassing a broad range of scales and media. The projects, divided into distinct but often overlapping research themes, include a museum courtyard program inspired by the Voronoi cell-packing algorithm (PS1 Loop); an outdoor light installation featuring hovering cones that capture and interact with solar energy, rainwater, and sound (Hover); a garment designed to turn inside out as it unravels (Mobius Dress); and a landscape design that weaves technology and texture into an integrated and interactive landscape (Tripanel). Packed with drawings, diagrams, and photographs of each project's design process, Expanded Practice provides an inspirational look into one of the most exciting young firms working in architecture today.
This volume describes the life and works of Samuel ben h ofni Gaon of Baghdad and the dynamics of tenth-century Jewish culture. Included are the Judeo-Arabic texts and annotated translations of his "Treatise on the Commandments" and "Ten Questions." Winner of the Ben-Zvi prize 1998.
Part architectural guidebook and part critique, Sky-High documents the pencil-thin, supertall towers that are transforming New York City's skyline as well as its streets. New York City's penchant for building skyward has reached new heights with its crop of supertall towers—those that rise at least 984 feet above the sidewalk. The city that never sleeps is also the city that never stops building ever higher, from the Woolworth and Chrysler buildings of an earlier race to the top to today's super luxury aeries of 57th Street's Billionaires' Row and the towers of the World Trade complex in Lower Manhattan. Bruce Katz's extraordinary photographs capture a dozen of these self-styled odes to wealth and power, alongside Eric P. Nash's incisive critique documenting the evolution of the skyline, past and present, and the supertalls' transformative effects on the contemporary cityscape. Among the twelve buildings featured are One World Trade Center, Three World Trade Center, 30 Hudson Yards, 35 Hudson Yards, One57, 432 Park Avenue, 53West53, Central Park Tower, and One Vanderbilt.
“A dense and scholarly book about . . . the relationship between the Nazi party and the occult . . . reveals stranger-than-fiction truths on every page.”—Daily Telegraph The Nazi fascination with the occult is legendary, yet today it is often dismissed as Himmler’s personal obsession or wildly overstated for its novelty. Preposterous though it was, however, supernatural thinking was inextricable from the Nazi project. The regime enlisted astrology and the paranormal, paganism, Indo-Aryan mythology, witchcraft, miracle weapons, and the lost kingdom of Atlantis in reimagining German politics and society and recasting German science and religion. In this eye-opening history, Eric Kurlander reveals how the Third Reich’s relationship to the supernatural was far from straightforward. Even as popular occultism and superstition were intermittently rooted out, suppressed, and outlawed, the Nazis drew upon a wide variety of occult practices and esoteric sciences to gain power, shape propaganda and policy, and pursue their dreams of racial utopia and empire. “[Kurlander] shows how swiftly irrational ideas can take hold, even in an age before social media.”—The Washington Post “Deeply researched, convincingly authenticated, this extraordinary study of the magical and supernatural at the highest levels of Nazi Germany will astonish.”—The Spectator “A trustworthy [book] on an extraordinary subject.”—The Times “A fascinating look at a little-understood aspect of fascism.”—Kirkus Reviews “Kurlander provides a careful, clear-headed, and exhaustive examination of a subject so lurid that it has probably scared away some of the serious research it merits.”—National Review
Catch up with current theories on a major public health menace! Adolescent smoking has increasingly become a concern as a public health issue, yet the theoretical and empirical literature in the area remains skimpy. Nicotine Addiction Among Adolescents furnishes researchers and medical professionals with a comprehensive overview of current theories and statistics. Moreover, it offers fresh empirical research as well as suggestions for promising avenues of investigation. The first half of Nicotine Addiction Among Adolescents provides a solid conceptual and practical context for studying adolescent nicotine addiction, drawing on the most advanced scholarly studies of why teenagers start smoking and the process of addiction. The second half evaluates nicotine replacement therapy, smoking interventions among substance-abusing adolescents, and smoking among teenage girls. Nicotine Addiction Among Adolescents addresses all phases of adolescent tobacco use. This valuable guide details: the pharmacological, psychological, and developmental factors that influence teen smoking behavior the hidden connection between depression, gender, and cigarettes the grounds for the debate over whether most teens become addicted to nicotine emerging practices and methods to help adolescents stop smoking links between smoking and other kinds of substance abuse ways to improve prevention and intervention programs unanswered questions about teenage smoking that demand further research Nicotine Addiction Among Adolescents recognizes the need for developmentally sensitive approaches for conceptualizing and treating nicotine addiction and offers you thought-provoking strategies and models that will spark future research.
Ethical Considerations When Preparing a Clinical Research Protocol, Second Edition, provides a foundation for improving skills in the understanding of ethical requirements in the design and conduct of clinical research. It includes practical information on ethical principles in clinical research, how to design appropriate research studies, how to consent and assent documents, how to get protocols approved, special populations, confidentiality issues, and the reporting of adverse events. The book's valuable appendix includes a listing of web resources about research ethics, along with a glossary, making it an invaluable resource for scientists collaborating in clinical trials, physician investigators, clinical research fellows, and more. - Walks investigators and trainees through the identification of the ethical aspects of each section of a clinical research protocol - Includes case histories that illustrate key points - Contains information on conducting clinical research within the pharmaceutical industry - Includes internet resources and worldwide web addresses for important research ethics documents and regulations - Contains a chapter on Study Design and Methodology that is purposely expanded to explicitly address biostatistical considerations
A survey of the emerging field of neuroethics that calls for a multidisciplinary, pragmatic approach for tackling key issues and improving patient care. Today the measurable health burden of neurological and mental health disorders matches or even surpasses any other cluster of health conditions. At the same time, the clinical applications of recent advances in neuroscience are hardly straightforward. In Pragmatic Neuroethics, Eric Racine argues that the emerging field of neuroethics offers a way to integrate such specialties as neurology, psychiatry, and neurosurgery with the humanities and social sciences, neuroscience research, and related healthcare professions, with the goal of tackling key ethical challenges and improving patient care. Racine provides a survey of the often diverging perspectives within neuroethics, offers a theoretical framework supported by empirical data, and discusses the neuroethical implications of such issues as media coverage of neuroscience innovation and the importance of public concerns and lay opinion; nonmedical use of pharmaceuticals for performance enhancement; and the discord between intuitive notions about consciousness and behavior and the scientific understanding of them. Racine proposes a pragmatic neuroethics that combines pluralistic approaches, bottom-up research perspectives, and a focus on practical issues (in contrast to other more theoretical and single-discipline approaches to the field). [He discusses ethical issues related to powerful neuroscience insights into the mechanisms underlying moral reasoning, cooperative behavior, and such emotional processes as empathy.] In addition, he outlines a pragmatic framework for neuroethics, based on the philosophy of emergentism, which identifies conditions for the meaningful contribution of neuroscience to ethics, and sketches new directions and strategies for meeting future challenges for neuroscience and society. Basic Bioethics series
A Science Friday pick for book of the year, 2019 One of America's top doctors reveals how AI will empower physicians and revolutionize patient care Medicine has become inhuman, to disastrous effect. The doctor-patient relationship--the heart of medicine--is broken: doctors are too distracted and overwhelmed to truly connect with their patients, and medical errors and misdiagnoses abound. In Deep Medicine, leading physician Eric Topol reveals how artificial intelligence can help. AI has the potential to transform everything doctors do, from notetaking and medical scans to diagnosis and treatment, greatly cutting down the cost of medicine and reducing human mortality. By freeing physicians from the tasks that interfere with human connection, AI will create space for the real healing that takes place between a doctor who can listen and a patient who needs to be heard. Innovative, provocative, and hopeful, Deep Medicine shows us how the awesome power of AI can make medicine better, for all the humans involved.
A Programmer’s Guide to C# 5.0 is a book for software developers who want to truly understand C#. Whether you’ve worked with C# before or with another general-purpose programming language, each fast-paced, focused chapter will take you straight to the heart of a feature of C# and show you why it works the way it does. Written by one-time C# Test Lead, Program Manager, and member of the original C# language design team, this book is an ideal companion to the C# Language Specification, and works both as a tutorial and as a reference guide. Now in its fourth edition, you will find up-to-date coverage of all the latest C# features, including Linq, covariance and contravariance, and async support. You’ll learn how to: Use C# features effectively, in the way they were intended Apply the newest C# features to your coding problems Streamline your database code using LINQ Use async support and the task parallel library to improve performance. Program more efficiently, effectively, and with real insight into this mature and exciting language, with A Programmer’s Guide to C# 5.0.
Argues that sovereign wealth funds and rogue nations are threatening the security of America's financial future, explaining how they undermine the economy and the stability of banking institutions.
The influence of compounds in the environment on the chemistry of plants is a topic which has economic and scientific implications of global importance. Selected presentations in this symposium covered several topics within this immense field, inclusive of air, soil, and aquatic sources of the compounds. As demonstrated in Chapter 4 by O'Keeffe et al. we have not restricted the discussion solely to negative aspects of anthropogenic compounds. Nor could we begin to cover comprehensively all major classes of environmental compounds in the air, soil or water that may have an effect on the phytochemistry of plants. Our intent was to focus on some of the timely and well publicized environmental constituents such as ozone, sulfur dioxide, acid rain, and others, to provide an authoritative publication specifically related to environ mental modifications of plant chemistry. The concept of this symposium originated with the Executive Committee of the Phytochemical Society of North America in 1983. It was brought to fruition during July 13-17, 1986 on the campus of the University of Maryland at the annual meeting of the PSNA through the efforts of the Symposium Committee composed of James A. Saunders and Lynn Kosak-Channing. Financial support for this meeting was provided by the Phytochemical Society of North America, as well as by generous contributions from E. I. du Pont de Nemours & Company and the U. S. Department of Agriculture. The Organizing Committee, consisting of J. A. Saunders (Chair), J. M. Gillespie, L. Kosak-Channing, E. H. Lee, J. P.
Over 500 pages of facts, statistics, and records of every match and every player for the Australian national Rugby Union team from the first match in June 1899 up to December 2023.
This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.
Pulsed Field Gel Electrophoresis: A Practical Guide is the first laboratory manual to describe the theory and practice of this technique. Based on the authors' experience developing pulsed field gel instruments and teaching procedures, this book provides everything a researcher or student needs to know in order to understand and carry out pulsed field gel experiments. Clear, well-tested protocols assume only that users have a basic familiarity with molecular biology. Thorough coverage of useful data, theory, and applications ensures that this book is also a lasting resource for more advanced practitioners of pulsed field gels. - Reviews all types of pulsed field gel electrophoresis - Describes all commercially available systems and summarizes advantages and limitations of each - Includes step-by-step protocols for sample preparation and analysis - Illustrated with photographs that depict - How to run gels: What the results should look like - What they look like when they go wrong - Covers applications to a wide range of organisms - Includes bibliography of over 900 publications and cross-referenced by topic, application, and organism
The condemnation of memory inexorably altered the visual landscape of imperial Rome. This volume catalogues and interprets the sculptural, glyptic, numismatic and epigraphic evidence for damnatio memoriae and ultimately reveals its praxis to be at the core of Roman cultural identity.
A remarkable compilation of over 400 pages of statistics and records of every match and every player for the Wales national Rugby Union team from the first match in February 1881 up to December 2023.
The new edition of this definitive textbook reflects the continuing reintegration of psychiatry into the mainstream of biomedical science. The research tools that are transforming other branches of medicine - epidemiology, genetics, molecular biology, imaging, and medicinal chemistry - are also transforming psychiatry. The field stands poised to make dramatic advances in defining disease pathogenesis, developing diagnostic methods capable of identifying specific and valid disease entities, discovering novel and more effective treatments, and ultimately preventing psychiatric disorders. The Neurobiology of Mental Illness is written by world-renowned experts in basic neuroscience and the pathophysiology and treatment of psychiatric disorders. It begins with a succint overview of the basic neurosciences followed by and evaluation of the tools that are available for the study of mental disorders in humans. The core of the book is a series of consistently organized sections on the major psychiatric disorders that cover their diagnostic classification, molecular genetics, functional neuroanatomy, neurochemistry and pharmacology, neuroimaging, and principles of pharmacotherapy. Chapters are written in a clear style that is easily accessible to practicing psychiatrists, and yet they are detailed enough to interest researchers and academics. For this second edition, every section has been thoroughly updated, and 13 new chapters have been added in areas where significant advances have been made, including functional genomics and animal models of illness; epidemiology; cognitive neuroscience; postmortem investigation of human brain; drug discovery methods for psychiatric disorders; the neurobiology of schizophrenia; animal models of anxiety disorders; neuroimaging studies of anxiety disorders; developmental neurobiology and childhood onset of psychiatric disorders; the neurobiology of mental retardation; the interface between neurological and psychiatric disorders; the neurobiology of circadian rhythms; and the neurobiology of sleep disorders. Both as a textbook and a reference work, Neurobiology of Mental Illness represents a uniquely valuable resource for psychiatrists, neuroscientists, and their students or trainees.
Essential C# 5.0 is a well-organized, no-fluff guide to the latest versions of C# for programmers at all levels of C# experience. Fully updated to reflect new features and programming patterns introduced with C# 5.0 and .NET 4.5, this guide shows you how to write C# code that is simple, powerful, robust, secure, and maintainable. Microsoft MVP Mark Michaelis and C# principal developer Eric Lippert provide comprehensive coverage of the entire language, offering a complete foundation for effective software development. The authors illustrate key constructs with succinct, downloadable code examples. Graphical mind maps at the beginning of each chapter outline the material that is covered and how individual topics interrelate. This edition also includes C# Coding Guidelines that call attention to today’s best practices for writing C# code. Separate indexes of C# versions 3.0, 4.0, and 5.0 make it easy to find answers specific to whatever version of C# you are using. Throughout, topics intended for beginners and advanced readers are clearly marked. If you’re new to C#, this guide will help you start writing significant code quickly. If you’re an experienced C# developer, you’ll gain insight into today’s most complex programming challenges and techniques as you master key C# 5.0 innovations such as async/await pattern. No matter how advanced your skills become, you’ll come to rely on this indispensable reference. Coverage includes Mastering C# data types, operators, control flow, methods, and parameters Making the most of C# object-oriented constructs, including classes, inheritance, interfaces, and more Building reliable, effective exception handling into your code Using generics, delegates, Lambda expressions, and events to reduce code complexity Learning dynamic programming with reflection and attributes Querying virtually any type of data using LINQ with Query Expressions Creating custom collections that operate against business objects Understanding the Common Language Infrastructure and C# in the context of the .NET 4.5 development platform Taking advantage of declarative programming, embedded metadata, reflection, and attributes Thoroughly mastering multithreading and synchronization, including the new async/await paradigm Discussion of WinRT and programming in C# for Windows 8 Using P/Invoke, pointers, and direct memory manipulation to interoperate with code in other languages Understanding how C# programs relate to the underlying runtime
From new research and equipment to new procedures, applications, and approaches, the field of interventional cardiology is one of the fastest-changing areas in medicine. Increasing data and recent technological advances have resulted in exciting changes – and an even greater need for cutting-edge, authoritative guidance on current practice. Textbook of Interventional Cardiology, 8th Edition, covers the theories, trends, and applications of diagnostic and interventional cardiology that cardiologists, cardiac surgeons, vascular surgeons, referring physicians, and advanced practitioners need to know. - Focuses on the latest treatment protocols for managing patients at every level of complexity. - Includes all-new chapters on Coronary Stenting, Diagnosis and Treatment of Coronary Microvascular Disease, Percutaneous Transcatheter Valve in Valve Implantation, and Percutaneous Tricuspid Valve Repair. - Features hundreds of new illustrations, tables, and boxes for visual clarity and quick reference. - Offers expanded coverage of transcatheter aortic valve interventions with extensive updates on practice implications. - Discusses hot topics such new atherectomy devices, percutaneous mitral valve replacement, and percutaneous treatment of paravalvular leak. - Provides the unique insights of expert leaders in the field who have pioneered today's innovative devices and techniques and lend their own analysis of practical, evidence-based clinical applications. - Presents the most recent data on how genomics and genetics impact interventional cardiology. - Provides an in-depth understanding of cardiology, making it well suited for cardiology and interventional cardiology exam preparation. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.
Visual Studio Tools for Office is both the first and the definitive book on VSTO 2005 programming, written by the inventors of the technology. VSTO is a set of tools that allows professional developers to use the full power of Visual Studio .NET and the .NET Framework to put code behind Excel 2003, Word 2003, Outlook 2003, and InfoPath 2003. VSTO provides functionality never before available to the Office developer: data binding and data/view separation, design-time views of Excel and Word documents inside Visual Studio, rich support for Windows Forms controls in a document, the ability to create custom Office task panes, server-side programming support against Office, and much more. Carter and Lippert cover their subject matter with deft insight into the needs of .NET developers learning VSTO. This book Explains the architecture of Microsoft Office programming and introduces the object models Teaches the three basic patterns of Office solutions: Office automation executables, Office add-ins, and code behind a document Explores the ways of customizing Excel, Word, Outlook, and InfoPath, and plumbs the depths of programming with their events and object models Introduces the VSTO programming model Teaches how to use Windows Forms in VSTO and how to work with the Actions Pane Delves into VSTO data programming and server data scenarios Explores .NET code security and VSTO deployment
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