Mathematical models and computer simulations play important roles in developing a better understanding of learning and memory mechanisms. Models provide a means for representing, integrating, and manipulating diverse and complex empirical data. This chapter provides an overview of computational studies of learning and memory in invertebrates, including gene regulatory networks, signal transduction cascades, single neurons, and neural networks. These computational studies are helping to link specific component processes (e.g., changes in protein levels and phosphorylation, modulation of membrane conductances, synaptic plasticity, and network architecture) to features of nonassociative and associative learning. Moreover, these computational studies highlight mechanistic features that are common among different animals and common to multiple forms of learning and memory. Thus, computational analyses provide insights into the relationships among simple and complex forms of learning.
This small book describes a fifteen-day car trip you can take in Apulia and the neighboring regions of Basilicata and Abruzzo, passing through important archeological, artistic, and cultural locations. The itinerary starts from the town of Ortona a Mare in Abruzzo. It goes through several Apulia cities and then to Matera, a stunning city in Basilicata, vibrant with history, cave hotels, and authentic Italian food. The time to visit Matera is now. The ancient town, 2019 European Culture Capital, could be Italy's next great attraction. The itinerary then returns to Apulia and touches other several cities, to arrive in Alberobello, known for its Trulli, whitewashed stone huts with conical roofs - the hilltop Rione Monti district has hundreds of them. It continues with other towns in Apulia and the Gargano peninsula, with its National Park, home to the last remaining part of the oak and beech Forest Umbra that once covered most of central Europe. It passes through Termoli to end up again in Ortona al Mare. It also describes a possible visit to the Tremiti Islands from Termoli and how to get there. There are several ferry companies providing transportation services to these islands, the service is available from different ports, with or without the possibility of bringing your car with you. Finding the right solution for your needs using Google is at least confusing if you don't understand Italian; you can spend a full day to figure out what is available and when. In the guide, I present you with the outcome of my research. The guide includes a chapter on the food and wine of Apulia. A list of local recipes is present; the original recipes' links are active in the digital editions.
Do you want to learn about Greece? So come to Sicily. It is a paradox, for sure, but only to a certain extent. The Greek cities of Sicily (Agrigento, Selinunte, Segesta, Syracuse, to mention the most important) were among the most beautiful of the Hellenic world. Nowadays, to visit the Valley of Temples at Agrigento or to watch a summer performance in the great Greek Theatre of Syracuse is to plunge yourself into the remote Hellenic past. And this is also true in Sicily for many other historical eras and civilizations, from the Spanish to the French. With the sole exception of Arab rule, that has left a scarce physical testimony. Sicily is a book of history and art history, a compendium of the greatest civilizations and cultures of all time. A sunny island whose landscape is rich in contrasts, with a splendid coastline and refined, delicious and varied cuisine of traditional flavors and exquisite aromas. The quintessence of Mediterranean culture, yet also dense with intellectual complexity and refinement, so well represented by the literary masterpieces of Luigi Pirandello, Giuseppe Tomasi di Lampedusa, Leonardo Sciascia, Gesualdo Bufalino and today, Andrea Camilleri. This guide leads you in a week-long drive in the Island of Sicily: starting with Messina, touching the Aeolian Islands, and then Taormina, Acireale, Catania, Syracuse, Caltagirone, Piazza Armerina with its Roman Villa, Agrigento with the Greek Temples, Porto Empedocle, Selinunte, to arrive in Palermo, with a visit to Solunto and Monreale. It includes a section on Sicilian food. It includes color photos and descriptions of the attractions of all the localities touched. It is ideal for use on your smartphone, it contains links to the websites of many reviews for the best-recommended restaurants that are at the location described. P { margin-bottom: 0.08in; }
An accessible introduction to modern physics that focuses on wormholes and discusses among other topics their structure, stability, dynamics, operation as time machines, utility as portals to parallel universes, and their implications for the distant future of humanity. Read the wormhole FAQ and the bullet point "principles" scattered throughout to quickly absorb the basics of wormhole physics. Go back and read the interstitial material for greater depth. Written by a physicist with years of experience in gently introducing physics to the mathematically challenged, it also covers the history of wormhole physics and delineates the unsolved problems at the forefront of research.
Often called the Switzerland of the South, Calabria covers the mountainous toe of Italy. Here one finds the most beautiful forests, and the hillsides are covered with the white leaves of ancient olive trees. Traveling between the Calabrian mountains, in a vast land of magnificent beauty, you are in a region bounded with two seas of approximately eight hundred kilometers coasts, where for this particular configuration, incalculable views are present and where the nature has plot in a magnificent way the lines that talent and human work must follow, or art efforts can improve. Closed in the north with the Pollino and Orsomarso imponent relieves, Calabria has a predominantly territory mountainous, vast green reserves, and lakes with robust splendor inside Sila, demoted summit to peak into the sea on the Range Coast, very high silver firs and rushing streams on the Serre, the last window on the Mediterranean between the Aspromonte summits. Calabria’s 800 km of pristine coastline are described in detail, as well as the Nature parks and reserves. The Sports available are included. This guide also leads you in a drive through Calabria, starting from Maratea and then going to Papasidero, Cosenza, the Sila mountains, Crotone, Pizzo Calabro, Tropea and Capo Vaticano, Locri, Pentedattilo, to end up in Reggio Calabria. It includes photos and descriptions of the attractions of all the localities touched, as well as travel info. It includes info on regional food. It contains many reviews for the best-recommended restaurants that are at the location described; you have the necessary information ready: the name, address and telephone number are included in the guide together with the review.
This work contains the papers of the thirteenth Conference on “Antitrust between EU Law and national law”, held in Treviso on May 24 and 25, 2018 under the patronage of the European Lawyers Union – Union des Avocats Européens (UAE), the Associazione Italiana per la Tutela della Concorrenza - the Italian section of the Ligue Internationale du Droit de la Concurrence (LIDC)-, the Associazione Italiana Giuristi di Impresa (AIGI), the European Company Lawyers Association (ECLA), and the Associazione Antitrust Italiana (AAI). Some of the papers have been extensively reviewed and updated by the authors prior to publication. The contributions contained in this volume are the result of an in-depth analysis and study of the most salient issues arising from the application of antitrust rules, carried out by experienced and high-ranking professionals, in-house lawyers, academics and EU/national and international institutional representatives who attended the Conference. They deal with extremely topical issues, lying at the heart of current antitrust debate. Some of the most contemporary topics include those related to private antitrust enforcement after the implementation of Directive 2014/104/EU, and to the interplay between antitrust and intellectual property rights. Ample consideration is also given to recent developments in the field of new technologies and the related antitrust issues, as well as to the relations between consumer protection and antitrust. * * * Questo volume contiene gli atti del XIII Convegno sul tema “Antitrust fra Diritto Nazionale e Diritto dell’Unione Europea”, tenutosi a Treviso il 24 e 25 maggio 2018 con il patrocinio dell’Unione degli Avvocati Europei (UAE), dell’Associazione Italiana per la Tutela della Concorrenza - sezione italiana della Ligue Internationale du Droit de la Concurrence (LIDC) -, dell’Associazione Italiana dei Giuristi di Impresa (AIGI), della European Company Lawyers Association (AEJE-ECLA) e dell’Associazione Antitrust Italiana (AAI). Alcuni contributi sono stati sostanzialmente rivisti ed aggiornati dagli autori prima della pubblicazione. Gli articoli contenuti nel presente volume sono il frutto del prezioso lavoro di studio e approfondimento delle più interessanti tematiche correlate all’applicazione del diritto antitrust, svolto da qualificati esponenti del mondo professionale, imprenditoriale, accademico ed istituzionale, intervenuti al Convegno. I contributi pubblicati affrontano temi di estrema rilevanza, che rappr sentano il cuore delle problematiche antitrust oggi maggiormente dibattute, tra le quali spiccano, per attualità, quelle connesse al private enforcement ed al risarcimento dei danni in seguito dell’attuazione della Direttiva 2014/104/UE, nonché alle interazioni tra diritto antitrust e diritti di proprietà intellettuale. Ampio spazio è inoltre dedicato alle tematiche concernenti le nuove tecnologie e la loro rilevanza dal punto di vista antitrust, nonché ai rapporti tra tutela del consumatore e diritto antitrust.
The most comprehensive, current sickle cell disease resource—for both clinicians and researchers A Doody's Core Title for 2023! The first and only resource of its kind, Sickle Cell Disease examines this blood disorder through both clinical and research lenses. More than 80 dedicated experts in the field present their combined clinical knowledge of basic mechanisms, screening, diagnosis, management, and treatment of myriad complex complications of a single base point mutation in the human genome. Case studies with “How I Treat” authoritative insights provide overviews of common and rare complications, and Key Facts offer at-a-glance high-yield information. Filled with clinical photos, illustrations, numerous original diagrams, and with free updates available online, this unmatched resource covers: Mechanisms of sickle cell disease Historic and current research approaches The latest work in gene therapy and editing Guidelines for patient care, diagnosis, unique cases, and therapies Rare and common complications, including domestic and internationally relevant topics Psychosocial and supportive care The newest standards of therapy and future treatment options in children and adults Cardiopulmonary complications
L'Italia centrale tirrenica nel VII sec. a.C. è ormai da tempo pienamente inserita in un ricco circuito di scambi e commerci a livello mediterraneo. In questo complesso quadro di scambi e contatti, che hanno portato a una radicale trasformazione in ampi settori dell'Italia preromana, uno degli aspetti forse più evidenti e facilmente percepibili è l'evoluzione nelle produzioni artigianali etrusche e italiche di un interessante e variegato bestiario fantastico, che in buona parte affonda le sue radici in ambito lato sensu orientale e greco, ma la cui sopravvivenza nel corso del VII secolo a.C. e oltre, è in un certo senso garantita dalle differenti riletture locali, che spesso rielaborano liberamente i modelli allotri dando vita a figurazioni parzialmente o del tutto nuove.Il volume Il bestiario fantastico di età orientalizzante nella Penisola Italiana, che inaugura i Quaderni della serie Aristonothos, Scritti per il Mediterraneo Antico, ha lo scopo di creare un dossier di partenza, con il fine di attirare attenzione sul fenomeno e suscitare un dibattito, coinvolgendo studiosi che da diversi punti di vista (archeologico, storico artistico, antropologico, ecc.) e a diversi gradi di approfondimento, hanno incontrato nella propria ricerca questo aspetto della cultura figurativa."--Page 4 de la couverture
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