To honor the life and times of The Focus Theatre, this new title provides an insight into Ireland's only arthouse theatre from the people who were there. Through interviews, articles, short memoirs, and photographs, Stanislavski in Ireland: Focus at Fifty tracks the theatre from its inception. Many of Ireland's leading theatre and film artists trained and worked at Focus, including Gabriel Byrne, Joan Bergin, Olwen Fouere, Brendan Coyle, Rebecca Schull, Johnny Murphy, Sean Campion, Tom Hickey, and Mary Elizabeth and Declan Burke-Kennedy. The book comes complete with a chronological list of productions.
Presenting real-life case studies of child sexual abuse in the Caribbean as a basis for discussing interventions and models of practice that are relevant for a wide range of cultural and social settings, this multi-disciplinary text will be of interest to scholars, professionals and practitioners alike. Contributors to this volume demonstrate how sexual abuse is never just a problem of the individual: structures of inequality and the intersection of the factors they give rise to help to explain why some children are more at risk of abuse than others. Furthermore, the sub-systems in which lives are lived can compound risk and vulnerability or alternatively, can be sources of support and change. This book draws on these ideas to discuss practice across a range of service users: children, adolescent girls, teenage mothers, children with learning disabilities, fathers, mothers, women who abuse, juvenile sex offenders and children in residential care. p>
The information given in this book tries to capture the essence of the sheer dynamicity of the cell along with useful tips on how to address critical rate limiting steps in the process of exploration and investigation of its capacity to regenerate, rebuild and replenish from within. The definitions of stem cells, stemness, and the niche concept continue to undergo revisions. In adult vertebrates, hematopoietic and some non-hematopoietic progenitors are synthesized within specialized niches of bone marrow. They migrate to designated tissues, and are either trans-differentiated or become quiescent and settle down. These form the stem cell niche reservoir in all tissues. Not only the primary hematopoietic tissue but all organs and tissues are also capable of generating progenitors which are either synthesized from these migrants or are direct recruits from other tissues. In the niches, the cells settle down and await their turn to either make more clones like themselves or differentiate and mobilize in an exigency. Thus progenitors are important reserves, to be multiplied and deployed or travel as important message bearing molecules via blood as circulating progenitors which can home to their allocated destinations. Upon reaching, specific integrins and selectins help them “dock” and “port” and they may be reprogrammed to induce further differentiation and help repopulate the denuded tissue. In pulmonary fibrosis and asthma, progenitors from both systemic circulation and local stem cell niches have been found to participate in the myriad ramifications of repair, replacement and regeneration of lost or diseased tissue. Whether they are lung specific or global in origin and role remain to be explored. Research tools, fundamental concepts, techniques, methodologies and standard operating protocols and animal models and human extrapolations, have been discussed in a concise way along with detailed description and discussion on the appropriate rationale to introduce the subject to the casual reader and provide valuable tactical information to the specialist in Regenerative Medicine. I sincerely hope you enjoy the work and appreciate the hard work that has gone into designing and executing elegant experiments by many researchers in the field. The branch is multi-disciplinary and I hope that the readers will not be limited to biologists alone.
NEW! Restructured table of contents presents anatomically related medical and trauma chapters sequentially for quick reference. NEW! Considerations for critical care in the ED. NEW! Considerations for the transgender patient. NEW! Section on human trafficking in the Interpersonal Violence and Abuse chapter. NEW! Section on violent risk assessment in the Workplace Violence chapter. NEW! Color photos insert visually highlights and clarifies key content. EXPANDED! Substance Abuse and Addiction Emergencies chapter covers methamphetamines, bath salts, marijuana edibles, opioid abuse/prescription drug abuse, heroin/Narcan, and substance abuse disorder. EXPANDED! Chapter on end-of-life includes information on palliative care considerations. UPDATED! Infectious Diseases chapter addresses coronavirus 19 (COVID-19), Ebola, and vector-borne malaria.
Increasing global competition, combined with shrinking budgets, are forcing managers to find new ways of operating. To compete successfully, companies must now use technology and resources (particularly human resources) to their full potential. Much of the research in the area of performance management has suggested that, while it has great potential to contribute dramatically to the bottom line, it rarely works. The third edition of Managing Performance Improvement looks at why performance systems fail, and explores the tools and techniques to overcome this failure. This best selling text provides practical, specific advice to managers and students enabling them to plan for, and then manage, performance improvement.
This book will provide practitioners, researchers and counsellor trainers with the knowledge they need to influence more competent therapeutic practice with a diverse clientele. It is a companion volume to Volume 7 in the Multicultural Aspects of Counseling series.
A newly-updated edition of the definitive textbook on Aboriginal Health issues Binan Goonj, 3rd Edition: Bridging cultures in Aboriginal health is a comprehensive Indigenous health text which addresses key topics in a clear and accessible manner. Thoroughly updated and revised, the latest edition of Binan Goonj sheds light upon the many multidisciplinary topics within the complex field of Indigenous health. With chapter titles including Empowerment in Aboriginal Health and Aboriginal Communities Today, this authoritative health resource has been widely adopted as a teaching text across Australia. Despite years of research, policy changes and interventions, it is widely documented that the health status of many Aboriginal people remains the poorest in Australia. Binan Goonj, 3rd Edition: Bridging cultures in Aboriginal health explores the processes and practices underlying this situation, while providing practical strategies to work towards redressing it. This latest edition will engage a diverse readership and challenge students and health professionals alike to examine their own values and the use of power in Australian society. Elsevier’s Evolve website provides extensive support material for nursing and health professions faculty and students, including: • discussion questions • suggested reading on Aboriginal health and related topics • web links • an instructor’s manual featuring course delivery tips including topics such as adult learning, attitudinal change, colonisation, government policies, Indigenous media sites and cross-cultural education resources • video links specific to chapters in this latest edition of Binan Goonj • completely updated to reflect major Indigenous health policy changes since the second edition • an in-depth exploration of the collaboration between Aboriginal and non-Aboriginal people • the use of Aboriginal health case studies and critical incidences to bring academic discussion and analysis to life • processes that have been successfully incorporated into 18 years of cross-cultural workshops
The present book addresses the multi-disciplinary nature of Translational Outcomes Research, which is a watershed for nearly all the disciplines of Life and Health Sciences, along with the Materials Sciences including but not limited to Zoology, Botany, Microbiology, Biochemistry, Physiology, Nanotechnology, the Medical Sciences, Bioengineering, Biophysics, Medicinal Chemistry, Structural Biology, Biostatistics and Bioinformatics. This book, for the first time, addresses the basic premises of fundamental research in facilitating drug discovery. One chapter is dedicated to a novel generation of platforms with novel camelid antibodies and their technological extensions, while another focuses on functional food and nutraceuticals. The book begins with a thorough overview of what translational outcomes research connotes and what the current status of research in the area is, and goes on to elucidate various pertinent preclinical disease models and their uses in basic and application based research in the Life Sciences. How basic approaches to screening and characterization vis-à-vis their role in amelioration of the two cardinal problems of inflammation and degeneration involved in most diseases is elucidated. The book ends with a discussion of the relevance and importance of using Bio Green technology in Translational Outcomes, addressing the need to fill the gap between academia and industry and clinics that can arise through direct or indirect collaboration between the stakeholders and emphasizing the need for an eco-friendly approach so as not to jeopardize the fine balance that holds life on earth in harmony.
A dead body. A missing will. An evil relative. The good news is, Great Grammy has a plan. The bad news is, she's the dead body. Rosie and Baker are hiding something. Something big. Their great grandmother made them promise to pretend she's alive until they find her missing will and get it in the right hands. The will protects the family house from their grandmother, Grim Hesper, who would sell it and ship Rosie and Baker off to separate boarding schools. They've already lost their parents and Great Grammy--they can't lose each other, too. The siblings kick it into high gear to locate the will, keep their neighbors from prying, and safeguard the house. Rosie has no time to cope with her grief as disasters pop up around every carefully planned corner. She can't even bring herself to read her last-ever letter from Great Grammy. But the lies get bigger and bigger as Rosie and Baker try to convince everyone that their great grandmother is still around, and they'll need more than a six-month supply of frozen noodle casserole and mountains of toilet paper once their wicked grandmother shows up! This unexpectedly touching read reminds us that families are weird and wonderful, even when they're missing their best parts. With humor, suspense, and a testament to loyalty, Ena Jones takes two brave kids on an unforgettable journey. Includes four recipes for Great Grammy's survival treats.
“Perspectives in Inflammation Biology” outlines detailed studies using preclinical murine models in Inflammation. The book is meant for academicians, industry persons, research scholars and students alike. The detailed perspective for a beginner and the exhaustive methodologies and analyses outlined, for the veteran researcher, makes this book a unique link between someone who is thinking of embarking on a study of inflammation and one who is delving deep into this area of specialization. The book deals with asthma and allergy as specific disease areas of inflammation of the lung, aseptic peritonitis as a disease of systemic inflammation and details how each role player in its pathophysiology has a unique niche of activity. Data acquisition, sequentiality and analyses in context demonstrate how each role player is validated systematically to become a target for drug discovery. Methods and models used in the course of my work and their relevance will demonstrate to the researcher how a study can be developed from an idea. Further into a researcher’s ongoing work, this book is meant to stimulate new questions and pave ways for better dissection of a phenomenon. The highlights of this book are the detailed tables tabulating sub species of immune cells, their inflammatory recruitment indices, their translation into tissue-to-tissue traffic of the inflammatory stimulus and the delicate interplay of resident structural cells, cells recruited from circulation, their feedback poiesis in bone marrow, their instruction in the lymphoid organs and tissues as well as the non-cellular mediators synthesized from corresponding genetic instruction. The book shall definitely help students and researchers how a disease can be simplified from its complex ramifications and network of implications and put back into perspective and the whole thing falls into place without an intimate understanding of the mechanism and the compelling circumstances that causes a disease, a drug hunter cannot hope to begin her quest. To find the “Achilles’ heel” and effectively neutralize the enemy!
Thirteen-year-old Clayton’s new assignment for the Special Service means adopting a new identity—indefinitely. He has to leave behind his friends and beloved lacrosse team to live as "Max Carrington," a student at the Sydney Brown School, where the President’s son Kyle is a seventh grader. But Clayton isn’t the only new kid at school and there’s something odd about his fellow outsider, James Scott. Is James hiding something, and is he a threat to Kyle? The chaos of undercover life keeps Clayton on his toes as he rushes from one crisis to the next, while a cutthroat school election brings out some strong personalities at Sydney Brown. To make matters worse, Clayton’s new lacrosse team is set to play Masters Academy in the playoffs. It looks like he will face off against his best friends and former teammates! Clayton’s adventures are better than ever in this funny and heartwarming sequel to Clayton Stone, At Your Service.
Have you ever been frustrated with not enough peace, joy, meaning, or fulfillment? Do you feel there is more to life than what you are experiencing? An overflow in every area of your life is achievable—in fact, it is already given to you. Jesus came with one mission—that you may have life and have it more abundantly. In The Abundant Woman, author Dr. Ena Tychus takes a unique approach to showing how women can uncover this truth starting with the mind. She defines abundance as having a superfluous supply of something, whatever your something is, so much so that this something can overflow into another life or community and make impact. Offering a unique perspective on abundance, each chapter brings you closer to the fulfilled promise of living abundantly every day.
This is a Pageburst digital textbook; the product description may vary from the print textbook. Written by emergency nurses for emergency nurses, this comprehensive, evidence-based resource covers the issues and procedures that are often unique to the emergency department. New developments and changes in clinical practice are incorporated throughout. The user-friendly format features more than 350 high-quality illustrations and 150 tables that highlight essential concepts and offer quick access to vital information. Key coverage includes clinical fundamentals, treatment for trauma and medical-surgical emergencies, the foundations of emergency nursing practice, and special populations. 58 contributors offer valuable insights from a broad range of clinical positions in rural, suburban, and urban areas. High-quality radiographs and other diagnostic images help you learn to identify common conditions - especially head trauma, fractures, and dislocations. Logically organized, chapters are grouped into six sections for quick access to important content: Foundations of Emergency Nursing, Professional Practice, Clinical Foundations of Emergency Nursing, Major Trauma Emergencies, Medical and Surgical Emergencies, and Special Patient Populations. Tables and boxes highlight and summarize critical information for at-a-glance reference. A separate unit on special patient populations covers topics such as child abuse, elder abuse, intimate partner violence, sexual assault, substance abuse and behavioral/pediatric/obstetrical emergencies. Priority nursing diagnoses are highlighted in a quick-reference appendix to help you focus on the most serious problems. Five new chapters bring you the most reliable, up-to-date information on these key topics: Management of the Critical Care Patient in the Emergency Department Family Presence During Resuscitation Forensic Nursing Nuclear, Biological, and Chemical Agents of Mass Destruction Influenza: Seasonal, Avian, and Pandemic Expanded coverage of shock and sepsis provides essential information on pathophysiology and diagnosis, with valuable guidelines for managing these patients. A detailed discussion of various types of triage systems and triage acuity ratings examines valid and reliable methods for differentiating between patients who require immediate treatment and those who can wait. Additional coverage of behavioral health emergencies includes new information on agitation, substance abuse, and suicide prevention.
Have you ever been frustrated with not enough peace, joy, meaning, or fulfillment? Do you feel there is more to life than what you are experiencing? An overflow in every area of your life is achievable--in fact, it is already given to you. Jesus came with one mission--that you may have life and have it more abundantly. In The Abundant Woman, author Dr. Ena Tychus takes a unique approach to showing how women can uncover this truth starting with the mind. She defines abundance as having a superfluous supply of something, whatever your something is, so much so that this something can overflow into another life or community and make impact. Offering a unique perspective on abundance, each chapter brings you closer to the fulfilled promise of living abundantly every day.
This book discusses the mechanisms leading to immune-mediated tissue rejection following the hypothesis that independent of the disease process the final effector mechanism is shared by most (but not all) pathologies and it is relatively simple. The book covers evidence gathered to support the thesis by studies performed in humans during rejection or in experimental models and will focus particularly (but not exclusively) on the analysis of the rejected tissue rather than the systemic circulation. Several disease processes are discussed including example of chronic inflammatory process without resolution of the pathologic process and acute one with resolution of the pathologic process (clearance of pathogen, rejection of tumor) or unwanted tissue destruction (allograft rejection, autoimmunity).
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