Elena L. Paley's Books

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

By: Elena L. Paley

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Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

By: Elena L. Paley

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome metabolome vagus nerve brain circuit in Alzheimer's disease and associated diseases and medical conditions, including dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea, which may increase the risk of other conditions. This book also discusses the vagus nerve-related conditions, including Arnold's reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in the book also address an important question of which one is more important for human health and intellectual abilities: the human genome or the human microbiome? The conceptual model of food and gut microbial tryptamine vagus nerve circuit is also presented in this book. - Addresses the emerging hypothesis of a dysfunctional microbiome vagus nerve brain circuit in Alzheimer's disease and associated diseases and medical conditions - Covers dementia, aging, COVID-19, autoimmune conditions, and inflammatory skin condition rosacea - Presents the conceptual model of food and gut microbial tryptamine vagus nerve circuit - Covers human health and intellectual abilities in the context of both the human genome and the human microbiome

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Page Count

536

Publisher

Elsevier

Published Date

ISBN 10

0443151989

ISBN 13

9780443151989

Tryptamine Microbiota-Deregulated Aminoacyl-tRNA Biosynthesis

A Conceptual Evolution of the Role of Microbiota Tryptamine in Human Diseases

By: Elena L. Paley

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Tryptamine Microbiota-Deregulated Aminoacyl-tRNA Biosynthesis

A Conceptual Evolution of the Role of Microbiota Tryptamine in Human Diseases

By: Elena L. Paley

Tryptamine Microbiota-Deregulated Aminoacyl-tRNA Biosynthesis: A Conceptual Evolution of the Role of Microbiota Tryptamine in Human Diseases provides a detailed investigation into tryptamine, its underlying mechanisms, and metabolism across multiple diseases. The book explores key concepts of tryptamine, its biosynthetic pathways, and its influence in disease, specifically focusing on the Alzheimer's disease-associated gut bacterial sequence (ADAS). Various neurodegenerative conditions are covered alongside cancer, diabetes, infections, and chromosomal aberrations. Additionally, a chapter on gut tryptamine in domestic and agricultural animals is included. The book closes with case studies involving FDG-PET imaging in the context of tryptamine-treated mouse models and Alzheimer's disease patients.This book elucidates the implications of the gut microbiota-mediated tryptamine metabolism for human health, sharing insights into disease etiology, mechanisms, testing, prevention, and treatment. It is an ideal reference for researchers across the biomedical sciences. - Provides a detailed investigation into tryptamine and its role in human health - Explores the relationship between microbiome tryptamine metabolome and a range of diseases, including diabetes, cancer, Alzheimer's disease and Parkinson's disease - Considers the role of tryptamine in cell death and the impairment of genome activities - Paves the way for advances in disease prevention and treatment pathways

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Page Count

320

Publisher

Elsevier

Published Date

ISBN 10

0443288313

ISBN 13

9780443288319

Microbial Metabolism and Disease

By: Elena L. Paley

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Microbial Metabolism and Disease

By: Elena L. Paley

Microbiome Metabolic Pathways and Disease provides insight into the interaction of microbial metabolic pathways in the human body and the impact these can have on a variety of diseases. By analyzing these pathways the book seeks to investigate how these metabolic processes can be targeted and manipulated in order to treat various disorders and diseases. Topics covered in the book include microbial shikimate pathways, protein biosynthesis, tryptophan metabolites, microbiome metabolic engineering, fecal microbiota transplantation, and virulence factors. Additionally, a variety of conditions are covered, such as disorders associated with metabolic syndromes, serotonin syndromes, Alzheimer's disease, and Covid-19, providing a detailed overview of how metabolic pathways of microbiome can impact health and disease in the human body. - Explores microbial metabolic pathways in the human body and implications for disease - Investigates specific steps involved in metabolic reactions in the human microbiome, including shikimate pathways and tryptophan pathways - Considers a variety of diseases and disorders, such as Alzheimer's disease, metabolic syndromes, Crohn's disease and Covid-19 - Includes analysis of various amino acids and enzymes in microbial and human cells and how these can impact health

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Page Count

308

Publisher

Academic Press

Published Date

ISBN 10

0323884466

ISBN 13

9780323884464

Protein Biosynthesis Interference in Disease

By: Elena L. Paley

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Protein Biosynthesis Interference in Disease

By: Elena L. Paley

Protein Biosynthesis Interference in Disease offers a thorough discussion and overview of protein biosynthesis interference, its mechanisms of action, and influence over disease processes. This book examines the role of protein biosynthesis interference in Alzheimer's and other neurodegenerative conditions, cancer and inflammatory disorders, with specific attention paid to the biochemical dynamics of tryptamine, biogenic amines and aminoacyl-tRNA synthetases in these pathologies. Methods of regulating protein translation and interference mechanisms, including gene therapy, are presented, empowering biochemists, molecular biologists, disease researchers, and health professionals to understand the underlying factors of protein disease and improve patient outcomes. - Enables biochemists, molecular biologists and disease researchers to advance disease prevention, laboratory testing, and treatment pathways for protein biosynthesis interference related disorders - Examines the biochemical and molecular basis of protein biosynthesis interference in neurodegenerative disorders, cancer and inflammatory conditions, among other diseases - Analyzes tryptamine, biogenic amines, and aminoacyl-tRNA synthetases dynamics in protein translation and possible treatment pathways regulating protein biosynthesis

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Page Count

297

Publisher

Academic Press

Published Date

ISBN 10

0128234865

ISBN 13

9780128234860

Microbial Metabolism and Disease

By: Elena L. Paley

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Microbial Metabolism and Disease

By: Elena L. Paley

Microbiome Metabolic Pathways and Disease provides insight into the interaction of microbial metabolic pathways in the human body and the impact these can have on a variety of diseases. By analyzing these pathways the book seeks to investigate how these metabolic processes can be targeted and manipulated in order to treat various disorders and diseases. Topics covered in the book include microbial shikimate pathways, protein biosynthesis, tryptophan metabolites, microbiome metabolic engineering, fecal microbiota transplantation, and virulence factors. Additionally, a variety of conditions are covered, such as disorders associated with metabolic syndromes, serotonin syndromes, Alzheimer's disease, and Covid-19, providing a detailed overview of how metabolic pathways of microbiome can impact health and disease in the human body. Explores microbial metabolic pathways in the human body and implications for disease Investigates specific steps involved in metabolic reactions in the human microbiome, including shikimate pathways and tryptophan pathways Considers a variety of diseases and disorders, such as Alzheimer's disease, metabolic syndromes, Crohn's disease and Covid-19 Includes analysis of various amino acids and enzymes in microbial and human cells and how these can impact health

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Page Count

306

Publisher

Elsevier

Published Date

ISBN 10

0323884458

ISBN 13

9780323884457

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

By: Elena L. Paley

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Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

By: Elena L. Paley

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery focuses on the emerging hypothesis of a dysfunctional microbiome - metabolome - vagus nerve - brain circuit in Alzheimer's disease and associated diseases and medical conditions, including dementia, aging, COVID-19, and autoimmune conditions including rosacea. This volume also discusses the vagus nerve-related conditions including Arnold's reflex, laryngopharyngeal reflux, duodenogastric reflux, gastroesophageal reflux, and related pulmonary diseases. The subjects covered in this book also address an important question: which one is more important for human health and intellectual abilities: the human genome or human microbiome? The conceptual model of food and gut microbial tryptamine - vagus nerve circuit is also presented in this volume. Addresses the emerging hypothesis of a dysfunctional microbiome - vagus nerve - brain circuit in Alzheimer's disease and associated diseases and medical conditions Covers dementia, aging, COVID-19, and autoimmune conditions including rosacea Presents the conceptual model of food and gut microbial tryptamine - vagus nerve circuit Covers human health and intellectual abilities in the context of both the human genome and the human microbiome

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Age

Page Count

534

Publisher

Elsevier

Published Date

ISBN 10

0443191220

ISBN 13

9780443191220

Protein Biosynthesis Interference in Disease

By: Elena L. Paley

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Protein Biosynthesis Interference in Disease

By: Elena L. Paley

Average ratings

N/A

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Solve jigsaw puzzle

Age

Page Count

297

Publisher

Academic Press

Published Date

ISBN 10

0128234865

ISBN 13

9780128234860

Book's by Elena L. Paley

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

Tryptamine Microbiota-Deregulated Aminoacyl-tRNA Biosynthesis

Tryptamine Microbiota-Deregulated Aminoacyl-tRNA Biosynthesis

Microbial Metabolism and Disease

Microbial Metabolism and Disease

Protein Biosynthesis Interference in Disease

Protein Biosynthesis Interference in Disease

Microbial Metabolism and Disease

Microbial Metabolism and Disease

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

Microbiome Metabolome Brain Vagus Nerve Circuit in Disease and Recovery

Protein Biosynthesis Interference in Disease

Protein Biosynthesis Interference in Disease

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