Edward a. Boyden's Books

Novel Therapeutic Targets for Antiarrhythmic Drugs

By: George Edward Billman

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Novel Therapeutic Targets for Antiarrhythmic Drugs

By: George Edward Billman

PROFILES POTENTIAL TREATMENT APPROACHES FOR CARDIAC ARRHYTHMIAS Cardiac arrhythmias of ventricular origin are responsible for the deaths of nearly half a million Americans each year while atrial fibrillation accounts for about 2.3 million cases per year, a rate that is projected to increase 2.5 fold over the next half century. Effectively managing these cardiac rhythm disorders remains a major challenge for both caregivers and the pharmaceutical industry. Filling a gap in the current literature, Novel Therapeutic Targets for Antiarrhythmic Drugs presents the latest treatments for cardiac arrhythmias alongside comprehensive presentations of basic cardiac physiology and pharmacology. Written by leading experts in their research areas, this invaluable resource offers both practitioners and researchers a one-stop guide that brings together previously dispersed information. The text consists of four sections: Section One comprehensively reviews basic cardiac electrophysiology, the mechanisms responsible for arrhythmias in the setting of ischemia, and basic pharmacology of antiarrhythmic drugs. Section Two addresses safety pharmacology, including the concept of "repolarization reserve," safety challenges, and regulatory issues for the development of novel antiarrhythmic drugs. Section Three describes several novel pharmacological targets for antiarrhythmic drugs, including both ion channel and non-ion channel targets. Section Four describes promising non-pharmacological antiarrhythmic interventions including selective cardiac neural disruption or nerve stimulation, aerobic exercise training, and diet (omega-3 fatty acids). Offering an unparalleled look at the current state and future direction of cardiac arrhythmia treatment, Novel Therapeutic Targets for Antiarrhythmic Drugs provides an important resource to advanced students, working researchers, and busy professionals alike.

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Page Count

610

Publisher

John Wiley & Sons

Published Date

ISBN 10

0470261005

ISBN 13

9780470261002

Assisted Ventilation of the Neonate E-Book

By: Jay P. Goldsmith,Edward Karotkin,Gautham Suresh,Martin Keszler

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Assisted Ventilation of the Neonate E-Book

By: Jay P. Goldsmith,Edward Karotkin,Gautham Suresh,Martin Keszler

Extensively updated and featuring a new editorial team, the 6th Edition of Assisted Ventilation of the Neonate, by Drs. Jay P. Goldsmith, Edward Karotkin, Gautham Suresh, and Martin Keszler, continues to be a must-have reference for the entire NICU. Still the only fully comprehensive guide in this fast-changing area, it provides expert guidance on contemporary management of neonatal respiratory diseases, with an emphasis on evidence-based pharmacologic and technologic advances to improve outcomes and quality of life in newborns. A new full-color design and chapter layout combine for quick and easy reference. Covers everything you need to know about respiratory management in neonates: general principles and concepts; assessment, diagnosis and monitoring methods; therapeutic respiratory interventions; adjunctive interventions; and special situations and outcomes. Covers basic concepts of pulmonary pathophysiology and gives practical guidance on providing neonatal respiratory support with a variety of techniques, so you can learn both basic and advanced methods in one volume. Offers more than 30 appendices that help you quickly find normal values, assessment charts, ICU flow charts, procedure steps and other useful, printable forms. Reflects the rapid evolution of approaches to respiratory care, including the shift to non-invasive support, as well as changes in oxygenation targets, high-flow nasal therapy, volume ventilation, and sophisticated microprocessor-controlled ventilators. Completely new information on many previously covered topics, including ethical and legal issues related to neonatal mechanical ventilation. Features 11 entirely new chapters, including Radiography, Lung Ultrasound and Other Imaging Modalities; Non-invasive Monitoring of Gas Exchange; Airway Evaluation: Bronchoscopy, Laryngoscopy, Tracheal Aspirates; Special Ventilation Techniques; Cardiovascular Therapy and PPHN; and Quality Improvement in Respiratory Care . Includes new opening summaries that highlight key information in each chapter.

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Page Count

631

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

0323392156

ISBN 13

9780323392150

Global Objects

Toward a Connected Art History

By: Edward S. Cooke

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Global Objects

Toward a Connected Art History

By: Edward S. Cooke

A bold reorientation of art history that bridges the divide between fine art and material culture through an examination of objects and their uses Art history is often viewed through cultural or national lenses that define some works as fine art while relegating others to the category of craft. Global Objects points the way to an interconnected history of art, examining a broad array of functional aesthetic objects that transcend geographic and temporal boundaries and challenging preconceived ideas about what is and is not art. Avoiding traditional binaries such as East versus West and fine art versus decorative art, Edward Cooke looks at the production, consumption, and circulation of objects made from clay, fiber, wood, and nonferrous base metals. Carefully considering the materials and process of making, and connecting process to product and people, he demonstrates how objects act on those who look at, use, and acquire them. He reveals how objects retain aspects of their local fabrication while absorbing additional meanings in subtle and unexpected ways as they move through space and time. In emphasizing multiple centers of art production amid constantly changing contexts, Cooke moves beyond regional histories driven by geography, nation-state, time period, or medium. Beautifully illustrated, Global Objects traces the social lives of objects from creation to purchase, and from use to experienced meaning, charting exciting new directions in art history.

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Page Count

336

Publisher

Princeton University Press

Published Date

ISBN 10

0691184739

ISBN 13

9780691184739

Book's by Edward a. Boyden

Novel Therapeutic Targets for Antiarrhythmic Drugs

Novel Therapeutic Targets for Antiarrhythmic Drugs

Assisted Ventilation of the Neonate E-Book

Assisted Ventilation of the Neonate E-Book

Global Objects

Global Objects

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