Filled with industrial examples emphasizing the practical applications of crystallization methodologies Based on the authors' hands-on experiences as process engineers at Merck, Crystallization of Organic Compounds guides readers through the practical aspects of crystallization. It uses plenty of case studies and examples of crystallization processes, ranging from development through manufacturing scale-up. The book not only emphasizes strategies that have been proven successful, it also helps readers avoid common pitfalls that can render standard procedures unsuccessful. The goal of this text is twofold: Build a deeper understanding of the fundamental properties of crystallization as well as the impact of these properties on crystallization process development. Improve readers' problem-solving abilities by using actual industrial examples with real process constraints. Crystallization of Organic Compounds begins with detailed discussions of fundamental thermodynamic properties, nucleation and crystal growth kinetics, process dynamics, and scale-up considerations. Next, it investigates modes of operation, including cooling, evaporation, anti-solvent, and reactive crystallization. The authors conclude with special applications such as ultrasound in crystallization and computational fluid dynamics in crystallization. Most chapters feature multiple examples that guide readers step by step through the crystallization of active pharmaceutical ingredients (APIs). With its focus on industrial applications, this book is recommended for chemical engineers and chemists who are involved with the development, scale-up, or operation of crystallization processes in the pharmaceutical and fine chemical industries.
Macular degenertaion is the leading cause of blindness for those over the age of 65 and affects as many as 15 million North Americans. That number is projected to grow to an epidemic 30 million by 2010. "Getting old and going blind is not your only option! What most eye doctors are telling their patients is that there is no treatment for this disease... and that simply isn't true." These controversial words come from one of the nation's leading authorities on eye disease, Dr. Edward L. Paul, Jr. This ground breaking book discloses the latest breakthroughs and treatments for macular degeneration. Debunking the myths that surround this blinding disease, Dr. Paul disucusses new research evolving in the field of nutrition as well as cutting edge therapies in electro medicine such as MCS™ Therapy. "MCS™ is a new safe, nonsurgical, inexpensive and painless treatment that is helping over 75% of the patients treated," says Dr. Paul. In this book, you'll learn: How to dramatically improve your vision in 4 days. Why your eye doctor doesn't know about these new therapies. How inexpensive nutritional supplements may save your eyesight. How taking one simple action will improve your chances of recovery by 350%. Conquering macular degeneration is finally achievable and there is now hope where previously there was none. Dr. Paul's book uncovers secrets that will truly become the medicine of the millennium.
Examines the deleterious effects of the U.S. failure to focus on protecting the Iraqi population for most of the military campaign in Iraq and analyzes the failure of a technologically driven counterinsurgency (COIN) approach. It outlines strategic considerations relative to COIN; presents an overview of the conflict in Iraq; describes implications for future operations; and offers recommendations to improve the U.S. capability to conduct COIN.
Never in the field of human conflict was so much owed by so many to so few' Seventy-five years on the unforgettable words of Winston Churchill ring as powerfully as they did in August 1940 when the young men of the RAF stood as the last line of defence against Hitler's far more powerful Luftwaffe.This emotional yet factual book describes the three and a half months (10 July 31 October 1940) battle day-by-day and covers the essential details of every one of the 540 young pilots who died in this critical campaign that saved Britain from invasion by the Nazis.Thanks to the authors painstaking research we are given a short biography of each pilots and learn of their actions and the manner of their deaths, their squadrons and planes.The result is a unique record and fitting memorial of the courage and sacrifice of this select band of heroes. The text is enhanced by photographs of the individuals themselves.
A biography of George W. Bush, showing how he ignored his advisors to make key decisions himself--most in invading Iraq--and how these decisions were often driven by the President's deep religious faith.
Christ. The Christian Experience in the Modern World focuses on the question of salvation for all people. Using seven 'anthropological constants', Schillebeeckx innovatively shows the social and political relevance of faith. Inspired by liberation and feminist theologies, he puts strong emphasis on human experience and on the importance of examining church teaching in its historical context. This volume is a testimony of Schillebeeckx' ground breaking attempt to rethink doctrine in the light of the research on the historical Jesus. Instead of starting with Christianity's great creedal statements about Christ and the Trinity, he focuses on the subjective experience of the first generations of believers as expressed in the New Testament. This choice stirred considerable controversy and a Vatican investigation but inspired and still keeps to inspire readers in their personal approach to Christian faith.
A signature volume in the NIV-based New American Commentary series, New Testament professor Mark Taylor offers his exposition of the popular book of 1 Corinthians to give readers a deeper understanding of its content and context.
A comprehensive compilation of the available experimental and theoretical vibrational data for organometallic compounds and its role in evaluating the structures, bonding, and properties of these key compounds This unique book offers a thorough review of the literature dealing with vibrational data obtained using various phases, including matrices, reported for organometallic compounds from infrared spectra, Raman spectra, and several other techniques. It is the only one that compiles the available experimental and theoretical vibrational data on these compounds, and which discusses the importance of this information and its role in evaluating structures, bonding, and other important properties. It also treats the use of DFT and other theoretical calculations to analyze the vibrational data and to predict properties associated with these compounds. The book also includes vibrational data for organic species that form on metal and other surfaces. Vibrational Spectra of Organometallics: Theoretical and Experimental Data offers complete coverage of: Carbide, Alkylidyne, Alkylidene, Alkyl, and Alkane Derivatives; Noncyclic Carbon Clusters and Unsaturated Hydrocarbon Derivatives; and Cyclic, Unsaturated Organometallic Derivatives. By summarizing work that has already been done on organometallic compounds, it serves as an important reference for those studying their vibrational spectra and will, in the end, lead to a clearer understanding of other research that needs to be done in order to help researchers determine new research directions. An important reference for those studying the vibrational spectra of organometallic compounds Gathers the existing experimental and theoretical vibrational data and discusses its significance in assessing structures, bonding, and other principle properties Includes DFT methods for the interpretation of spectra, which has been one of the major developments of the last two decades Vibrational Spectra of Organometallics: Theoretical and Experimental Data is an important reference for researchers and practitioners in the areas of inorganic, organometallic, organic, and surface chemistry who have an interest in using vibrational data to characterize the bonding, composition, reactions, and structures of organometallic compounds, and organic species that are formed on various surfaces.
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