Edward C. Keefer's Books

Foreign relations of the United States, 1964-1968, V. 29, Pt. 2: Japan

By: Edward C. Keefer

Write a review Read reviews Take a Quiz Solve Book Puzzle

Foreign relations of the United States, 1964-1968, V. 29, Pt. 2: Japan

By: Edward C. Keefer

This volume is part of a subseries of the Foreign Relations of the United States that documents the most issues in the foreign policy of the 5 years (1964-1968) of the administration of Lyndon B. Johnson. This volume documents U.S. policy toward Japan during a period of increasing change in the relations between the two allies. Japan was fast becoming a major economic power while still relying on the United States for its security. A theme of the coverage, in fact, is the ongoing U.S. effort to encourage Japan to assume a greater role in its own military defense and to play a greater role on the world stage, especially in terms of economic development of the rest of Asia. Another major theme is U.S. efforts to encourage the continuation of a moderate, pro-Western Japanese Government.

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

372

Publisher

Government Printing Office

ISBN 10

016087632X

ISBN 13

9780160876325

Harold Brown

Offsetting the Soviet Military Challenge 1977-1981

By: Edward Coltrin Keefer

Write a review Read reviews Take a Quiz Solve Book Puzzle

Harold Brown

Offsetting the Soviet Military Challenge 1977-1981

By: Edward Coltrin Keefer

Author Edward Keefer chronicles and analyses the tenure of Secretary of Defense Harold Brown, who worked to counter the Soviet Union's growing military strength during the administration of President Jimmy Carter. Flush with cash from oil and gas development, the Soviets came closest to matching the United States in strategic power than at any other point in the Cold War, threatening to make the U.S. land-based missile force vulnerable to a first strike. By most reckonings the Kremlin also surpassed the West in conventional arms and forces in Central Europe, creating a direct threat to NATO. In response, Brown, a nuclear physicist, advocated for the development of more technologically advanced weapon systems to offset the Soviet military advantage, but faced Carter's efforts to reign in the defense budget. Eventually the secretary, backed by the JCS, the national security adviser, and key members of Congress, persuaded a reluctant Carter to increase defense spending for the last two years of his term. As a result weapons development such as stealth technology, precision-guided bombs, and cruise missiles went forward. These initiatives and more provided a head start for the acclaimed Ronald Reagan revolution in defense. As the author points out, there was more continuity than contrast in defense policy between Carter and Reagan. The book also highlights Brown's policymaking efforts and his influence on Carter as the administration responded to international events such as the Middle East peace process, the Iran revolution and hostage crisis, the rise of radical Islam, negotiations with the Soviets over arms limitations, the Soviet invasion of Afghanistan, and the creation of a new security framework in the Persian Gulf region. Other topics cover policy toward Latin America Africa, China, and Southeast Asia. The book is also a history of the Defense Department, including the continual development of the All-Volunteer Force and the organizational changes that saw improved policy formulation and acquisition decisions. Political strategists, political scientists, international relations scholars, foreign policy advocates, historians, and political economists may be interested in this comprehensive historical reference for United States defense and foreign policy under the James (Jimmy) Carter administration. High school students pursuing research for essays and term papers for Government, Modern World History, and United States History may be interested in this resource. Additionally, undergraduate and graduate level students may be interested in this authoritative resource for research relating to international relations, public administration, military science, public policy economics, and introduction to political theory courses. Related products: Presidential History resources collection is available here: https: //bookstore.gpo.gov/catalog/presidential-history Other resources relating to the President James (Jimmy) Carter administration can be found here: https: //bookstore.gpo.gov/catalog/39-jimmy-carter Foreign Relations of the United States (FRUS) series resources can be found here: https: //bookstore.gpo.gov/catalog/foreign-relations-united-states-series-frus Other published works by the US Department of Defense, Office of the Secretary of Defense can be found here: https: //bookstore.gpo.gov/agency/office-secretary-defense

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

848

Publisher

U.S. Government Printing Office

Published Date

ISBN 10

0160937558

ISBN 13

9780160937552

Drug-Like Properties

Concepts, Structure Design and Methods from ADME to Toxicity Optimization

By: Li Di,Edward H Kerns

Write a review Read reviews Take a Quiz Solve Book Puzzle

Drug-Like Properties

Concepts, Structure Design and Methods from ADME to Toxicity Optimization

By: Li Di,Edward H Kerns

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution, metabolism, elimination) properties, and acceptable toxicology properties, to become a drug product that will successfully complete human Phase I clinical trials. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates. This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, and metabolized safely and stably. Review chapters provide context and underscore the importance of key concepts such as pharmacokinetics, toxicity, the blood-brain barrier, diagnosing drug limitations, prodrugs, and formulation. Building on those foundations, this thoroughly updated revision covers a wide variety of current methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties for process and product improvement. From conducting key assays for interpretation and structural analysis, the reader learns to implement modification methods and improve each ADME property. Through valuable case studies, structure-property relationship descriptions, and structure modification strategies, Drug-Like Properties, Second Edition, offers tools and methods for ADME/Tox scientists through all aspects of drug research, discovery, design, development, and optimization. - Provides a comprehensive and valuable working handbook for scientists and students in medicinal chemistry - Includes expanded coverage of pharmacokinetics fundamentals and effects - Contains updates throughout, including the authors' recent work in the importance of solubility in drug development; new and currently used property methods, with a reduction of seldom-used methods; and exploration of computational modeling methods

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

582

Publisher

Academic Press

Published Date

ISBN 10

0128013222

ISBN 13

9780128013229

The Americanization of Edward Bok

By: Edward William Bok

Write a review Read reviews Take a Quiz Solve Book Puzzle

The Americanization of Edward Bok

By: Edward William Bok

Bonded Leather binding

Average ratings

N/A

Write a review

Solve jigsaw puzzle

Age

Page Count

425

Published Date

ISBN 10

0781254280

ISBN 13

9780781254281

Book's by Edward C. Keefer

Foreign relations of the United States, 1964-1968, V. 29, Pt. 2: Japan

Foreign relations of the United States, 1964-1968, V. 29, Pt. 2: Japan

Harold Brown

Harold Brown

Drug-Like Properties

Drug-Like Properties

The Americanization of Edward Bok

The Americanization of Edward Bok

Username

Password

Username

Password

Password again

Birthday

Email