The world of medicine has become splintered into two factions, that of orthodoxy and its counterpart, alternative or complementary medicine. A problem with alternative medicine is, of course, that of anecdote and hearsay. The solution: the disclosure, in an unassailable fashion, of the underlying biochemical principles for alternative cancer therap
Why the Right Went Wrong offers a historical view of the right since the 1960s. Its core contention is that American conservatism and the Republican Party took a wrong turn when they adopted Barry Goldwater's worldview during and after the 1964 campaign. The radicalism of today's conservatism is not the product of the Tea Party, Washington Post columnist E.J. Dionne writes. The Tea Partiers are the true heirs to Goldwater ideology. The purity movement did more than drive moderates out of the Republican Party--it beat back alternative definitions of conservatism.--Publisher information.
This completely revised and expanded new edition covers the full range of techniques now available for the investigation of materials structure and accurate quantitative determination of microstructural features within materials. It continues to provide the best introductory resource for understanding the interrelationship between microstructure and physical, mechanical, and chemical properties, as well as selection and application of techniques for both basic and applied studies. In particular, changes have been made to reflect developments in analysis of nanoscale and biological materials.
The first two editions of this book were published by the American Society for Colposcopy and Cervical Pathology (ASCCP). This product is considered the standard of colposcopy and has the reputation of being the best selling educational teaching module for the physician, resident, or advanced practice clinician who wishes to bridge the gap between the obvious need for increased early detection of cervical, vaginal, and vulvar disease and the intensive education required for colposcopy. The purpose of the society and the book is to provide education about the lower genital tract through the use of colposcopy. This includes the disciplines of pathology, cytology, cytogenetics, preventive medicine, basic research, gynecologic oncology, and endocrinology which are relevant to the understanding of the pathophysiology of the disease processes of the lower genital tract. Features Include: •1815 color images; • Complete coverage of HPV related diseases, colposcopy and related topics; • Chapters added on adolescents and the expanding field of anal screening, diagnosis of anal HPV related precancer and cancer through high resolution anoscopy and treatment of anal and perianal neoplastic disease; • Updated algorithms and guidelines; • Companion website that includes searchable text, images and more.
Molecules Engineered Against Oncogenic Proteins and Cancer A comprehensive review of the latest molecular advances in cancer treatment Featuring 91 total small molecule kinase/KRAS inhibitors, 80 of which are FDA-approved, Molecules Engineered Against Oncogenic Proteins and Cancer documents the recent scientific advances that have transformed one of medicine’s most challenging areas—cancer treatment. Most of these inhibitors specifically block oncogene-induced carcinogenic proteins with results that have dramatically advanced the treatment of cancer. In addition, the structural formulas of more than 100 kinase/KRAS inhibitors in clinical trials are presented. With a very well-known chemist as an author, Molecules Engineered Against Oncogenic Proteins and Cancer includes information on: Each molecule’s structure, function of the kinase target and relevance to cancer, the drug discovery process, and molecular details of drug action Mutated protein kinases as oncoproteins and targets for inhibition, along with the details of discovery for each antitumor antikinase agent History of oncoprotein inhibitors and their role in advancing the treatment and understanding of cancer The discovery process as a whole, effective strategies for innovation, ongoing challenges, and a glimpse of the future of the field Combining the most significant recent discoveries in a unique and useful way, Molecules Engineered Against Oncogenic Proteins and Cancer is an essential resource for researchers and students in bioscience, medicine, chemistry, and oncology as well as for those at industrial companies involved in therapeutic discovery.
Trapped in a suffocating marriage by a domineering husband and the ongoing fight to save her younger brother from self-destruction, Rebecca Croft's determination to do the right thing appears unassailable. But when her carefully balanced existence is resolutely rocked by the arrival of a stranger from out of town, the opportunity to escape proves too hard to resist. By the time she discovers this meeting was no chance encounter, Rebecca is in too deep and quite likely in danger. 'Paper Boats' is the story of one woman's internal battle of loyalty and responsibility versus dreams and self-fulfillment. If only someone had warned her dreams often come at a price.
Flash Photolysis and Pulse Radiolysis: Contributions to the Chemistry of Biology and Medicine presents the interaction of radiation with biomolecules, which is either beneficial o deleterious to life. This book discusses the biochemical reactions that are not radiation-induced by selectively generating certain types of free radicals present in normal metabolic processes. Organized into nine chapters, this book begins with an overview of the principle of both pulse radiolysis and flash photolysis with photoelectric detection. This text then examines the applications of flash photolysis and pulse radiolysis to the chlorophylls, bile pigments, hemoglobin and myoglobin, and the porphyrins. Other chapters consider the carotenoids related to photosynthesis. This book discusses as well the role of proteins in nearly all biological processes, including enzymatic catalysis, muscular contraction, immune protection, mechanical support, and genetic information. The final chapter deals with the structures and importance of radiosensitizers. This book is a valuable resource for chemists and biochemists.
First published in 1981, Professor Mishan’s Economic Efficiency and Social Welfare: Selected Essays on Fundamental Aspects of the Economic Theory of Social Welfare is a collection of 22 pioneering essays written while the author was teaching at the London School of Economics and chosen to indicate landmarks in the development of his own thought. Professor Mishan, who also enjoys an international reputation as a popular writer on the impact of modern economic growth on social welfare, is among the foremost authorities in the field of resource allocation, and his influence in his subject area has been profound. Mishan’s essays, while generally accessible to the layman due to the author’s lucidity, his economy in the use of mathematical notation and his concern with perspective, are invaluable reading for the economics undergraduate. The essays are particularly relevant to upper level students of project appraisal, welfare economics and cost benefit analysis requiring a coherent survey of their field of study.
Founded in 1899, scenic Hollywood Forever Cemetery--the only cemetery located within the city of Hollywood--serves as the "permanent home" for many of Hollywood's most famous (and infamous) characters. Hollywood Forever Cemetery boasts a fascinating history surpassed only by the compelling stories of its famous residents. Behind its iron gates are the graves of Cecil B. DeMille, Rudolph Valentino, Douglas Fairbanks, Carl "Alfalfa" Switzer, Tyrone Power, Nelson Eddy, Marion Davies, Fay Wray, Mel Blanc, Johnny Ramone, Don Adams, Bebe Daniels, Bugsy Siegel, and a host of others whose memorials tell the history of Tinseltown in stone.
This practical, well-organized reference delves deeply into functional group transformations, to provide all the detailed information that researchers need. Topics are organized into the following sections: oxidation, reduction, asymmetric synthesis, and functional group manipulations Each section includes a description of the functional group transformation, the historical perspective, mechanisms, variations and improvements on the reaction, synthetic utilities and applications for the reaction, experimental details, and references to the primary literature Contributors are well-known and respected for their work on the specific name reactions.
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