This book is a completely revised new edition of the definitive reference on disorders of hemoglobin. Authored by world-renowned experts, the book focuses on basic science aspects and clinical features of hemoglobinopathies, covering diagnosis, treatment, and future applications of current research. While the second edition continues to address the important molecular, cellular, and genetic components, coverage of clinical issues has been significantly expanded, and there is more practical emphasis on diagnosis and management throughout. The book opens with a review of the scientific underpinnings. Pathophysiology of common hemoglobin disorders is discussed next in an entirely new section devoted to vascular biology, the erythrocyte membrane, nitric oxide biology, and hemolysis. Four sections deal with α and β thalassemia, sickle cell disease, and related conditions, followed by special topics. The second edition concludes with current and developing approaches to treatment, incorporating new agents for iron chelation, methods to induce fetal hemoglobin production, novel treatment approaches, stem cell transplantation, and progress in gene therapy.
Psychology 2ed will support you to develop the skills and knowledge needed for your career in psychology and within the professional discipline of psychology. This book will be an invaluable study resource during your introductory psychology course and it will be a helpful reference throughout your studies and your future career in psychology. Psychology 2ed provides you with local ideas and examples within the context of psychology as an international discipline. Rich cultural and indigenous coverage is integrated throughout the book to help your understanding. To support your learning online study tools with revision quizzes, games and additional content have been developed with this book.
This work provides comprehensive coverage of modern biochemical engineering, detailing the basic concepts underlying the behaviour of bioprocesses as well as advances in bioprocess and biochemical engineering science. It includes discussions of topics such as enzyme kinetics and biocatalysis, microbial growth and product formation, bioreactor design, transport in bioreactors, bioproduct recovery and bioprocess economics and design. A solutions manual is available to instructors only.
Focusing on the fundamental principles of nanoscience and nanotechnology, this carefully developed textbook will equip students with a deep understanding of the nanoscale. • Each new topic is introduced with a concise summary of the relevant physical principles, emphasising universal commonalities between seemingly disparate areas, and encouraging students to develop an intuitive understanding of this diverse area of study • Accessible introductions to condensed matter physics and materials systems provide students from a broad range of scientific disciplines with all the necessary background • Theoretical concepts are linked to real-world applications, allowing students to connect theory and practice • Chapters are packed with problems to help students develop and retain their understanding, as well as engaging colour illustrations, and are accompanied by suggestions for additional reading. Containing enough material for a one- or two-semester course, this is an excellent resource for senior undergraduate and graduate students with backgrounds in physics, chemistry, materials science and electrical engineering.
Synthesizes the research literature on legal issues that arise when school deans and department chairs perform their many duties. Pays particular attention to the judicial process, plus areas of employment, student affairs, and external regulation.
Adored by many, appalling to some, baffling still to others, few authors defy any single critical narrative to the confounding extent that James Baldwin manages. Was he a black or queer writer? Was he a religious or secular writer? Was he a spokesman for the civil rights movement or a champion of the individual? His critics, as disparate as his readership, endlessly wrestle with paradoxes, not just in his work but also in the life of a man who described himself as "all those strangers called Jimmy Baldwin" and who declared that "all theories are suspect." Viewing Baldwin through a cultural-historical lens alongside a more traditional literary critical approach, All Those Strangers examines how his fiction and nonfiction shaped and responded to key political and cultural developments in the United States from the 1940s to the 1980s. Showing how external forces molded Baldwin's personal, political, and psychological development, Douglas Field breaks through the established critical difficulties caused by Baldwin's geographical, ideological, and artistic multiplicity by analyzing his life and work against the radically transformative politics of his time. The book explores under-researched areas in Baldwin's life and work, including his relationship to the Left, his FBI files, and the significance of Africa in his writing, while also contributing to wider discussions about postwar US culture. Field deftly navigates key twentieth-century themes-the Cold War, African American literary history, conflicts between spirituality and organized religion, and transnationalism-to bring a number of isolated subjects into dialogue with each other. By exploring the paradoxes in Baldwin's development as a writer, rather than trying to fix his life and work into a single framework, All Those Strangers contradicts the accepted critical paradigm that Baldwin's life and work are too ambiguous to make sense of. By studying him as an individual and an artist in flux, Field reveals the manifold ways in which Baldwin's work develops and coheres.
Volume one of a three volume set which describes the military personalities and tactics during the American Civil War, presenting the stories and military campaigns of the Army of Northern Virginia under the direction of Robert E. Lee.
A comprehensive guide designed to enable CBT practitioners to effectively engage people from diverse cultural backgrounds by applying culturally-sensitive therapeutic techniques Adapts core CBT techniques including reattribution, normalization, explanation development, formulating, reality testing, inference chaining and resetting expectations High profile author team includes specialists in culturally-sensitive CBT along with world-renowned pioneers in the application of CBT to serious mental illness Contains the most up-to-date research on CBT in ethnic minority groups available
During World War II, the U.S. military lost some 35,000 aircraft to enemy action, training incidents, typhoons, aircraft carrier deck mishaps, mechanical failures or just normal wear-and-tear where aircraft were scrapped and used for parts to keep others flying. Many just failed to return from their missions. To date, the 15,069 aircraft represented in this 3-volume set is information initially transferred from hand-written "Aircraft History Cards" and are the total number of U.S. Navy, Marine Corps and Coast Guard aircraft lost between 7 December 1941 and 15 August 1945, and lost outside the continental United States (CONUS). Volume II represents the information on any aircraft lost that was attached to any of the 713 squadrons listed in the database. Given the thousands of hours that went into this effort, the author hopes that, as a 3-volume set of reference books, it provides assistance to others who are researching ship, squadron and aircraft histories.
Sized to fit in your pocket for quick reference, Handbook for Principles and Practice of Gynecologic Oncology, 3rd Edition, is packed with the essential information you need on the diagnosis and management of gynecologic cancers. Now in full color for the first time, this bestselling handbook features coverage of the most recent developments in the field, clear and concise data that support treatment recommendations, and numerous algorithms and tables throughout. Fellows, residents, and specialist trainees will benefit from authoritative coverage in an easily accessible format.
Over the past two decades, there has been a shift in research and industrial practice, and products traditionally manufactured primarily from wood are increasingly combined with other nonwood materials of either natural or synthetic origin. Wood and other plant-based fiber is routinely combined with adhesives, polymers, and other "ingredients" to produce composite materials. Introduction to Wood and Natural Fiber Composites draws together widely scattered information concerning fundamental concepts and technical applications, essential to the manufacture of wood and natural fiber composites. The topics addressed include basic information on the chemical and physical composition of wood and other lignocellulosic materials, the behavior of these materials under thermocompression processes, fundamentals of adhesion, specific adhesive systems used to manufacture composite materials, and an overview of the industrial technologies used to manufacture major product categories. The book concludes with a chapter on the burgeoning field of natural fiber-plastic composites. Introduction to Wood and Natural Fiber Composites is a valuable resource for upper-level undergraduate students and graduate students studying forest products and wood science, as well as for practicing professionals working in operational areas of wood- and natural-fiber processing. For more information on the Wiley Series in Renewable Resources, visit www.wiley.com/go/rrs Topics covered include: Overview of lignocellulosic material, their chemical and physical composition Consolidation behavior of wood and fiber in response to heat and pressure Fundamentals of adhesion Adhesives used to bond wood and lignocellulosic composites Manufacturing technology of major product types Fiber/plastic composites
Lee's Lieutenants: A Study in Command is the most colorful and popular of Douglas Southall Freeman's works. A sweeping narrative that presents a multiple biography against the flame-shot background of the American Civil War, it is the story of the great figures of the Army of Northern Virginia who fought under Robert E. Lee. The Confederacy won resounding victories throughout the war, but seldom easily or without tremendous casualties. Death was always on the heels of fame, but the men who commanded -- among them Jackson, Longstreet, and Ewell -- developed as leaders and men. Lee's Lieutenants follows these men to the costly battle at Gettysburg, through the deepening twilight of the South's declining military might, and finally to the collapse of Lee's command and his formal surrender in 1865. To his unparalleled descriptions of men and operations, Dr. Freeman adds an insightful analysis of the lessons learned and their bearing upon the future military development of the nation. Accessible at last in a one-volume edition abridged by noted Civil War historian Stephen W. Sears, Lee's Lieutenants is essential reading for all Civil War buffs, students of war, and admirers of the historian's art as practiced at its very highest level.
How did we first come to believe in a correspondence between writers' lives and their works? When did the person of the author—both as context and target of textual interpretation—come to matter so much to the way we read? This book traces the development of author centrism back to the scholarship of early Renaissance humanists. Working against allegoresis and other traditions of non-historicizing textual reception, they discovered the power of engaging ancient works through the speculative reconstruction of writers' personalities and artistic motives. To trace the multi-lingual and eventually cross-cultural rise of reading for the author, this book presents four case studies of resolutely experimental texts by and about writers of high ambition in their respective generations: Lorenzo Valla on the forger of the Donation of Constantine, Erasmus on Saint Jerome, the poet George Gascoigne on himself, and Fulke Greville on Sir Philip Sidney. An opening methodological chapter and exhortative conclusion frame these four studies with accounts of the central lexicon—character, intention, ethos, persona—and the range of genre evidence that contemporaries used to discern and articulate authorial character and purpose. Constellated throughout with examples from the works of major contemporaries including John Aubrey, John Hayward, Galileo, Machiavelli, and Shakespeare, this volume resurrects a vibrant culture of biographism continuous with modern popular practice and yet radically more nuanced in its strategic reliance on the explanatory power of probabilism and historical conjecture—the discursive middle ground now obscured from view by the post-Enlightenment binaries of truth and fiction, history and story, fact and fable.
Celebrated as one of America's frontier heroes, Daniel Boone left a legacy that made the Boone name almost synonymous with frontier settlement. Nathan Boone, the youngest of Daniel's sons, played a vital role in American pioneering, following in much the same steps as his famous father. In Nathan Boone and the American Frontier, R. Douglas Hurt presents for the first time the life of this important frontiersman. Based on primary collections, newspaper articles, government documents, and secondary sources, this well-crafted biography begins with Nathan's childhood in present-day Kentucky and Virginia and then follows his family's move to Missouri. Hurt traces Boone's early activities as a hunter, trapper, and surveyor, as well as his leadership of a company of rangers during the War of 1812. After the war, Boone returned to survey work. In 1831, he organized another company of rangers for the Black Hawk War and returned to military life, making it his career. The remainder of the book recounts Boone's activities with the army in Iowa and the Indian Territory, where he was the first Boone to gain notice outside Missouri or Kentucky. Even today his work is recognized in the form of state parks, buildings, and place-names. Although Nathan Boone was an important figure, he lived much of his life in the shadow of his father. R. Douglas Hurt, however, makes a strong case for Nathan's contribution to the larger context of life in the American backcountry, especially the execution of military and Indian policy and the settlement of the frontier. By recognizing the significant role that Nathan Boone played, Nathan Boone and the American Frontier also provides the recognition due the many unheralded frontiersmen who helped settle the West. Anyone with an interest in the history of Missouri, the frontier, or the Boone name will find this book informative and compelling.
This thoroughly revised second edition offers a child-centered, international perspective as it urges America to de-stigmatize alternate family forms. In this book's first edition, Philip L. Kilbride showed polygamy as the preferred marriage pattern in most parts of the nonwestern world and explained how plural marriage is surfacing in western countries to address economic and spiritual crises. In Plural Marriage for Our Times: A Reinvented Option? Second Edition, Kilbride and his coauthor, Douglas R. Page, update and enhance this thesis in light of contemporary circumstances, new studies, and current legal debates. This new edition examines plural marriage's benefits for children. It extends the discussion of polygamy and religion, especially the Muslim perspective on marriage and family; considers the illegal polygamy of immigrants; and looks at multiple marriage in African American communities, where "crisis polygamy" is a growing phenomenon. The authors suggest Americans consider plural marriage as a viable practice that can help reduce the divorce rate, better protect women and children, and serve as an alternative to the "fractured family" so prevalent in America today.
Pictures of Time Beneath examines three celebrated heritage landscapes: Adelaide’s Hallett Cove, Lake Callabonna in the far north of South Australia, and the World Heritage listed Willandra Lakes Region of New South Wales. It offers philosophical insights into significant issues of heritage management, our relationship with Australian landscapes, and an original perspective on our understanding of place, time, nation and science. Glaciers in Adelaide, cow-sized wombats, monster kangaroos, desert dunes littered with freshwater mussels, ancient oases and inland seas: a diverse group of deep-time imaginings is the subject of this ground-breaking book. Ideas about a deep past in Australia are central to broader issues of identity, belonging, uniqueness, legitimacy and intellectual community. This journey through Australia’s natural histories examines the way landscapes and landforms are interpreted to realise certain visions of the land, the nation and the past in the context of contemporary notions of geological heritage, cultural property, cultural identity and antiquity.
Winner, Clotilde P. Garcia Tejano Book Prize The opening campaign of the US-Mexican War transformed the map of each nation and shaped the course of conflict. Armed with a broad range of Mexican military documents and previously unknown US sources, Douglas Murphy provides the first balanced view of early battles such as Palo Alto and Resaca de la Palma. He reassesses previously covered territory and also poses new questions. Why did Mexico establish its defenses south of the Rio Grande while claiming territory north of the river? What was Mexico’s strategy in the campaign against the United States? What factors most affected Mexico’s defeat? In confronting these questions, Murphy shows that the campaign was a complex chess match with undercurrents of political intrigue, economic motivations, and personal animosities as much as military action. Two Armies on the Rio Grande will transform our understanding of the US-Mexican War.
In Creating the Modern South, Douglas Flamming examines one hundred years in the life of the mill and the town of Dalton, Georgia, providing a uniquely perceptive view of Dixie's social and economic transformation. "Beautifully written, it combines the rich specificity of a case study with broadly applicable synthetic conclusions.--Technology and Culture "A detailed and nuanced study of community development. . . . Creating the Modern South is an important book and will be of interest to anyone in the field of labor history.--Journal of Economic History "A rich and provocative study. . . . Its major contribution to our knowledge of the South is its careful account of the evolution and collapse of mill culture.--Journal of Southern History "Ambitious, and at times provocative, Creating the Modern South is a well-researched, highly readable, and engaging book.--Journal of American History
Bromley's Family Law' is a well-established and popular textbook with students and practitioners alike. This edition has been updated to take into account recent developments in family law.
This volume synthesizes and analyzes thirty years of hydrological research in the Danum Valley Conservation Area, a lowland dipterocarp rainforest in Sabah, Malaysia. Ian Douglas explores the role of water in the rainforest ecosystem, setting out the ecological, climatological and geological context of present-day hydrological processes, soil erosion and stream sedimentation. He emphasizes the role of extreme events and natural disturbances in sediment supplies and the evolution of drainage pathways and explains the pathways of rainfall and stream sediment. Douglas then explores the impacts caused by logging, the extreme pulses of sedimentation and the effects of log removal and logging road construction, examining the effects of major storms in the 20 years after tree harvesting. Methods of minimizing logging damage to soils and streams are discussed and the effects on flora and fauns are considered.
When Douglas Adams died in 2001, he left behind 60 boxes full of notebooks, letters, scripts, jokes, speeches and even poems. In 42, compiled by Douglas’s long-time collaborator Kevin Jon Davies, hundreds of these personal artefacts appear in print for the very first time. Douglas was as much a thinker as he was a writer, and his artefacts reveal how his deep fascination with technology led to ideas which were far ahead of their time: a convention speech envisioning the modern smartphone, with all the information in the world living at our fingertips; sheets of notes predicting the advent of electronic books; journal entries from his forays into home computing – it is a matter of legend that Douglas bought the very first Mac in the UK; musings on how the internet would disrupt the CD-Rom industry, among others. 42 also features archival material charting Douglas’s school days through Cambridge, Footlights, collaborations with Graham Chapman, and early scribbles from the development of Doctor Who, Hitchhiker’s and Dirk Gently. Alongside details of his most celebrated works are projects that never came to fruition, including the pilot for radio programme They’ll Never Play That on the Radio and a space-inspired theme park ride. Douglas’s personal papers prove that the greatest ideas come from the fleeting thoughts that collide in our own imagination, and offer a captivating insight into the mind of one of the twentieth century’s greatest thinkers and most enduring storytellers.
Rain forests represent the world's richest repository of terrestrial biodiversity, and play a major role in regulating the global climate. They support the livelihoods of a substantial proportion of the world's population and are the source of many internationally traded commodities. They remain (despite decades of conservation attention) increasingly vulnerable to degradation and clearance, with profound though often uncertain future costs to global society. Understanding the ecology of these diverse biomes, and peoples' dependencies on them, is fundamental to their future management and conservation. Tropical Rain Forest Ecology, Diversity, and Conservation introduces and explores what rain forests are, how they arose, what they contain, how they function, and how humans use and impact them. The book starts by introducing the variety of rain forest plants, fungi, microorganisms, and animals, emphasising the spectacular diversity that is the motivation for their conservation. The central chapters describe the origins of rain forest communities, the variety of rain forest formations, and their ecology and dynamics. The challenge of explaining the species richness of rain forest communities lies at the heart of ecological theory, and forms a common theme throughout. The book's final section considers historical and current interactions of humans and rain forests. It explores biodiversity conservation as well as livelihood security for the many communities that are dependent on rain forests - inextricable issues that represent urgent priorities for scientists, conservationists, and policy makers.
A snapshot in time. After thousands of hours of research and data entry over a 35-year period, the information on the disposition of some 25,000 US Navy, US Marine Corps and US Coast Guard aircraft needs to be published. These aircraft mainly represent those built and lost during World War II - between 7 December 1941 and 15 August 1945 - but this book also contains aircraft built before WWII that were lost during WWII or disposed of after WWII (lost during the Korean War, lost on training exercises, sold to private investors, currently located in museums and even some still proudly sitting as "gate guards" across the US, etc.).
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