Trusted by generations of cardiologists for the latest, most reliable guidance in the field, Braunwald’s Heart Disease, 11th Edition, remains your #1 source of information on rapidly changing clinical science, clinical and translational research, and evidence-based medicine. This award-winning text has been completely updated, providing a superior multimedia reference for every aspect of this fast-changing field, including new material about almost every topic in cardiology.
Ideal for cardiologists who need to keep abreast of rapidly changing scientific foundations, clinical research results, and evidence-based medicine, Braunwald’s Heart Disease is your indispensable source for definitive, state-of-the-art answers on every aspect of contemporary cardiology, helping you apply the most recent knowledge in personalized medicine, imaging techniques, pharmacology, interventional cardiology, electrophysiology, and much more! Practice with confidence and overcome your toughest challenges with advice from the top minds in cardiology today, who synthesize the entire state of current knowledge and summarize all of the most recent ACC/AHA practice guidelines. Locate the answers you need fast thanks to a user-friendly, full-color design with more than 1,200 color illustrations. Learn from leading international experts, including 53 new authors. Explore brand-new chapters, such as Principles of Cardiovascular Genetics and Biomarkers, Proteomics, Metabolomics, and Personalized Medicine. Access new and updated guidelines covering Diseases of the Aorta, Peripheral Artery Diseases, Diabetes and the Cardiovascular System, Heart Failure, and Valvular Heart Disease. Stay abreast of the latest diagnostic and imaging techniques and modalities, such as three-dimensional echocardiography, speckle tracking, tissue Doppler, computed tomography, and cardiac magnetic resonance imaging. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability.
Braunwald’s Heart Disease remains your indispensable source for definitive, state-of-the-art answers on every aspect of contemporary cardiology. Edited by Drs. Robert O. Bonow, Douglas L. Mann, Douglas P. Zipes, and Peter Libby, this dynamic, multimedia reference helps you apply the most recent knowledge in molecular biology and genetics, imaging, pharmacology, interventional cardiology, electrophysiology, and much more. Weekly updates online, personally selected by Dr. Braunwald, continuously keep you current on the most important new developments affecting your practice. Enhanced premium online content includes new dynamic cardiac imaging videos, heart sound recordings, and podcasts. With sweeping updates throughout, and contributions from a "who’s who" of global cardiology, Braunwald’s is the cornerstone of effective practice. Continuously access the most important new developments affecting your practice with weekly updates personally selected by Dr. Braunwald, including focused reviews, "hot off the press" commentaries, and late-breaking clinical trials. Practice with confidence and overcome your toughest challenges with advice from the top minds in cardiology today, who synthesize the entire state of current knowledge and summarize all of the most recent ACC/AHA practice guidelines. Locate the answers you need fast thanks to a user-friendly, full-color design with more than 1,200 color illustrations. Search the complete contents online at www.expertconsult.com. Stay on top of the latest advances in molecular imaging, intravascular ultrasound, cardiovascular regeneration and tissue engineering, device therapy for advanced heart failure, atrial fibrillation management, structural heart disease, Chagasic heart disease, ethics in cardiovascular medicine, the design and conduct of clinical trials, and many other timely topics. Hone your clinical skills with new dynamic cardiac imaging videos, heart sound recordings, and podcasts at www.expertconsult.com.
On the first day of July 1863, Robert E. Lee’s Army of Northern Virginia accidentally crossed swords with George Gordon Meade’s federal Army of the Potomac. They clashed at a tiny Pennsylvania crossroads called Gettysburg. Three days later, at least 22,000 Confederate men and boys were dead, wounded or captured, and the Yankees held the field when the river of bloodshed finally stopped. Gettysburg was General Lee’s worst defeat on an open field of battle. In The Court Martial of Robert E. Lee, a discouraged Confederate Congress summons General Lee to Richmond in December 1863, to face a board of inquiry on the Battle of Gettysburg. Through this speculative board of inquiry, the reader is drawn into the true history of the Army of Northern Virginia and the real political personalities and true political intrigue of Richmond in 1863. Will General Lee be relieved of command? Perhaps sent into retirement borne of catastrophic failure, leaving behind forever his beloved Army of Northern Virginia? The reader feels his pain and the anguish of a defeated general who wrote four months after Gettysburg that, “My heart and thoughts will always be with this army.”
**Selected for Doody's Core Titles® 2024 in Respiratory Therapy** You can breathe a little easier knowing there's a proven way to master respiratory pharmacology! For more than 30 years, Rau's Respiratory Care Pharmacology has been the preeminent text on the subject. With easy-to-grasp terminology, relatable explanations, and reader-friendly writing, it simplifies the process of learning pharmacology material like never before. Rau's is organized into three logical sections, covering the basics of respiratory care, frequently used drugs, and critical care medications. New to the 11th edition are recently approved FDA drugs, information on drug approvals, COVID-19 coverage, and new and updated Clinical Connection boxes that focus on important clinical questions, assisting you in connecting the information in the text to the clinical setting and addressing how Respiratory Therapists can help educate patients. - Clinical scenarios with follow-up SOAP assessment help you assess your comprehension of the material. - Self-assessment questions offer you thought-provoking opportunities to test your comprehension of key concepts. - Learning objectives parallel the levels tested by the NBRC® exams to help you identify important information that goes beyond memorization and recall. - Key terms with definitions provide easy access to the pharmacologic vocabulary you should embrace. - Key points boxes in each chapter highlight important concepts in the lesson. - Glossary of all key terms in the text aids you in understanding the terminology associated with respiratory care pharmacology. - Appendices on common Units and Systems of Measurement and Acceptable Mixtures provide references to need-to-know information such as abbreviations, conversion charts for temperatures, liquid metric and solids, and a simple drug compatibility chart for drug mixtures. - Alphabetical drug index provides a direct index to look up information based on drug name. - NEW and UPDATED! Clinical Connection boxes assist you in connecting information in the text to the clinical setting, including providing patients a better understanding of their clinical conditions as related to their drug treatments. - UPDATED! Chapter 1 reflects changes to drug approval. - UPDATED! Chapter 3 reflects changes in aerosol medication devices and addresses aerosol-generating device issues and COVID-19. - UPDATED! The latest FDA-approved medications are referenced in all chapters. - UPDATED! Current asthma (GINA) and COPD (GOLD) guidelines include COVID-19 treatment protocols. - Enhanced readability helps you more easily understand difficult material.
Jonathan Edwards has been recognized as the most influential evangelical theologian of all time. Before his death at the age of fifty-four, he had sparked a new movement of Reformed evangelicals who played a major role in fueling the rise of modern missions, preaching revivals far and wide, and wielding the cutting edge of American theology. He has never gone out of print, and Christians today continue to flock to seminars and conferences on him. In this biography of the great preacher and teacher, historian Douglas Sweeney locates for us the core and key to Edwards' enduring impact. Sweeney finds that Edwards' profound and meticulous study of the Bible securely anchored his powerful preaching, his lively theological passions and his discerning pastoral work. Beyond introducing you to Edwards' life and times, this book will provide you with a model of Christian faith, thought and ministry.
Praise for the First Edition "The obvious enthusiasm of Myers, Montgomery, and Vining and their reliance on their many examples as a major focus of their pedagogy make Generalized Linear Models a joy to read. Every statistician working in any area of applied science should buy it and experience the excitement of these new approaches to familiar activities." —Technometrics Generalized Linear Models: With Applications in Engineering and the Sciences, Second Edition continues to provide a clear introduction to the theoretical foundations and key applications of generalized linear models (GLMs). Maintaining the same nontechnical approach as its predecessor, this update has been thoroughly extended to include the latest developments, relevant computational approaches, and modern examples from the fields of engineering and physical sciences. This new edition maintains its accessible approach to the topic by reviewing the various types of problems that support the use of GLMs and providing an overview of the basic, related concepts such as multiple linear regression, nonlinear regression, least squares, and the maximum likelihood estimation procedure. Incorporating the latest developments, new features of this Second Edition include: A new chapter on random effects and designs for GLMs A thoroughly revised chapter on logistic and Poisson regression, now with additional results on goodness of fit testing, nominal and ordinal responses, and overdispersion A new emphasis on GLM design, with added sections on designs for regression models and optimal designs for nonlinear regression models Expanded discussion of weighted least squares, including examples that illustrate how to estimate the weights Illustrations of R code to perform GLM analysis The authors demonstrate the diverse applications of GLMs through numerous examples, from classical applications in the fields of biology and biopharmaceuticals to more modern examples related to engineering and quality assurance. The Second Edition has been designed to demonstrate the growing computational nature of GLMs, as SAS®, Minitab®, JMP®, and R software packages are used throughout the book to demonstrate fitting and analysis of generalized linear models, perform inference, and conduct diagnostic checking. Numerous figures and screen shots illustrating computer output are provided, and a related FTP site houses supplementary material, including computer commands and additional data sets. Generalized Linear Models, Second Edition is an excellent book for courses on regression analysis and regression modeling at the upper-undergraduate and graduate level. It also serves as a valuable reference for engineers, scientists, and statisticians who must understand and apply GLMs in their work.
The seventh edition of this two-volume narrative of English history draws on the most up-to-date primary and secondary research, encouraging students to interpret the full range of England's social, economic, cultural, and political past from its first inhabitants to the 2020s. A History of England, Volume 1: Prehistory to 1714 focuses on the key social, economic, cultural, environmental, intellectual, and political events and themes of English history up to the early eighteenth century. Topics include the Viking and Norman conquests of the eleventh century, the creation of the monarchy, the Reformation, and the Glorious Revolution of 1688. The text discusses events in Scotland, Wales, and Ireland as they affected developments in England. There is a new section dealing with the decline of belief in witchcraft. This book is essential introductory reading for students of the history of England and Britain.
This two-volume narrative of English history draws on the most up-to-date primary and secondary research, encouraging students to interpret the full range of England's social, economic, cultural, and political past. A History of England, Volume 1 (Prehistory to 1714), focuses on the most important developments in the history of England through the early 18th century. Topics include the Viking and Norman conquests of the 11th century, the creation of the monarchy, the Reformation, and the Glorious Revolution of 1688.
A good reference for statisticians and other analysts becoming involved in the popular field of 'gene mapping'." -- "American Journal of Human Genetics
Describes the men and women who made a lasting impact on Christian faith and experience. With over 1,500 biographical entries, this book is the most comprehensive resource available. It spans the first through the twentieth centuries--from Jesus and the apostles to Billy Graham and Mother Teresa. A great reference book for pastors, Bible students and teachers, or anyone desiring a one-volume biographical dictionary of who's who in Christian history.
Since the publication of its first edition, this book has served as one of the few available on the classical Adams spectral sequence, and is the best account on the Adams-Novikov spectral sequence. This new edition has been updated in many places, especially the final chapter, which has been completely rewritten with an eye toward future research in the field. It remains the definitive reference on the stable homotopy groups of spheres. The first three chapters introduce the homotopy groups of spheres and take the reader from the classical results in the field though the computational aspects of the classical Adams spectral sequence and its modifications, which are the main tools topologists have to investigate the homotopy groups of spheres. Nowadays, the most efficient tools are the Brown-Peterson theory, the Adams-Novikov spectral sequence, and the chromatic spectral sequence, a device for analyzing the global structure of the stable homotopy groups of spheres and relating them to the cohomology of the Morava stabilizer groups. These topics are described in detail in Chapters 4 to 6. The revamped Chapter 7 is the computational payoff of the book, yielding a lot of information about the stable homotopy group of spheres. Appendices follow, giving self-contained accounts of the theory of formal group laws and the homological algebra associated with Hopf algebras and Hopf algebroids. The book is intended for anyone wishing to study computational stable homotopy theory. It is accessible to graduate students with a knowledge of algebraic topology and recommended to anyone wishing to venture into the frontiers of the subject.
Other books present corporate finance approaches to the venture capital and private equity industry, but many key decisions require an understanding of the ways that law and economics work together. This revised and updated 2e offers broad perspectives and principles not found in other course books, enabling readers to deduce the economic implications of specific contract terms. This approach avoids the common pitfalls of implying that contractual terms apply equally to firms in any industry anywhere in the world. In the 2e, datasets from over 40 countries are used to analyze and consider limited partnership contracts, compensation agreements, and differences in the structure of limited partnership venture capital funds, corporate venture capital funds, and government venture capital funds. There is also an in-depth study of contracts between different types of venture capital funds and entrepreneurial firms, including security design, and detailed cash flow, control and veto rights. The implications of such contracts for value-added effort and for performance are examined with reference to data from an international perspective. With seven new or completely revised chapters covering a range of topics from Fund Size and Diseconomies of Scale to Fundraising and Regulation, this new edition will be essential for financial and legal students and researchers considering international venture capital and private equity. - An analysis of the structure and governance features of venture capital contracts - In-depth study of contracts between different types of venture capital funds and entrepreneurial firms - Presents international datasets from over 40 countries around the world - Additional references on a companion website - Contains sample contracts, including limited partnership agreements, term sheets, shareholder agreements, and subscription agreements
This volume examines Zambia's role in the search for African independence, unity and development, particularly in the context of southern Africa. It also analyses the problems of dependence and underdevelopment and their impact on foreign policymaking. By concentrating on the key issues and major crises that confronted Zambia's decision makers during the nation's first years, the authors explain the country's current preoccupations and future prospects. Although their primary focus is on Zambia, they also treat a range of substantive and theoretical issues.
Built on the premise that anyone can learn to use the R software, this book emphasizes using R to do useful things like writing papers and reports, creating graphs, and conducting simple data analysis.
Dr. Braunwald's masterwork returns ... bringing you the definitive guidance you need to overcome any challenge in clinical cardiology today, using the best approaches available! Hundreds of world authorities, many of them new to this edition, synthesize all of the recent developments that are revolutionizing practice - from the newest findings in molecular biology and genetics to the latest imaging modalities, interventional procedures, and medications. This multimedia e-dition includes not only the printed reference, but also access to the complete contents online, fully searchable, with regular updates and much more. The expertise of the contributors, the scope of the coverage, and the versatile, multimedia format all make this the ultimate reference for the practicing cardiologist. Locate the answers you need fast, thanks to a user-friendly, full-color design, complete with more than 1,500 color illustrations. Glean clinically actionable information quickly with Clinical Practice Points in every chapter. Access the complete contents of the 2-volume set online, fully searchable, plus regular updates to reflect the latest clinical developments · Focused Reviews · Commentaries · Late-Breaking Trials · and more. Apply the latest knowledge in your field with 7 new chapters on Acute Heart Failure · Device Therapy of Heart Failure · Emerging Therapies for Heart Failure · Complementary and Alternative Approaches to Management · Prevention and Management of Stroke · Hypertrophic Cardiomyopathy · and Coronary Arteriography Guidelines. Get fresh perspectives on your practice with contributions from more than 20 brand-new authors.
This book studies algebras and linear transformations acting on finite-dimensional vector spaces over arbitrary fields. It is written for readers who have prior knowledge of algebra and linear algebra. The goal is to present a balance of theory and example in order for readers to gain a firm understanding of the basic theory of finite-dimensional algebras and to provide a foundation for subsequent advanced study in a number of areas of mathematics.
A compiler translates a program written in a high level language into a program written in a lower level language. For students of computer science, building a compiler from scratch is a rite of passage: a challenging and fun project that offers insight into many different aspects of computer science, some deeply theoretical, and others highly practical. This book offers a one semester introduction into compiler construction, enabling the reader to build a simple compiler that accepts a C-like language and translates it into working X86 or ARM assembly language. It is most suitable for undergraduate students who have some experience programming in C, and have taken courses in data structures and computer architecture.
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