The central themes of Cell Boundaries concern the structural and organizational principles underlying cell membranes, and how these principles enable function. By building a biological and biophysical foundation for understanding the organization of lipids in bilayers and the folding, assembly, stability, and function of membrane proteins, the book aims to broaden the knowledge of bioscience students to include the basic physics and physical chemistry that inform us about membranes. In doing so, it is hoped that physics students will find familiar territory that will lead them to an interest in biology. Our progress toward understanding membranes and membrane proteins depends strongly upon the concerted use of both biology and physics. It is important for students to know not only what we know, but how we have come to know it, so Cell Boundaries endeavours to bring out the history behind the central discoveries, especially in the early chapters, where the foundation is laid for later chapters. Science is far more interesting if, as students, we can appreciate and share in the adventures—and misadventures—of discovering new scientific knowledge. Cell Boundaries was written with advanced undergraduates and beginning graduate students in the biological and physical sciences in mind, though this textbook will likely have appeal to researchers and other academics as well. Highlights the history of important central discoveries Early chapters lay the foundation for later chapters to build on, so knowledge is amassed High-quality line diagrams illustrate key concepts and illuminate molecular mechanisms Box features and spreads expand on topics in main text, including histories of discoveries, special techniques, and applications
Eine Einführung in alle Aspekte der finiten Elemente, jetzt schon in der 4. Auflage! Geboten wird eine ausgewogene Mischung theoretischer und anwendungsorientierter Kapitel mit vielen Beispielen. Schwerpunkte liegen auf Anwendungen aus der Mechanik, dem Wärmetransport, der Elastizität sowie auf disziplinübergreifenden Problemen (Strömungen von Fluiden, Elektromagnetismus). Eine nützliche und zuverlässige Informationsquelle für Studenten und Praktiker!
Species of aspergilli are common in man's environment and are responsible for a wide spectrum of human and animal disease, ranging in animals from mycotic abortion to aflatoxicosis and in humans from localized colonization of the ear or skin to life-threatening systemic infection of neutropenic patients. In recent times, invasive aspergillosis has become increasingly important as a cause of morbidity and death, initially in patients receiving immunosuppression prior to organ transplantation, and latterly in haematologic patients rendered neutropenic by underlying disease or chemotherapy. In some centres, the condition has been recorded in more than 40% of patients dying with acute leukaemia. Laboratory diagnostic procedures are not always helpful and the diagnosis depends largely on clinical parameters. The clinician is faced with yet another problem, that of management. At present, antifungal therapy of invasive aspergillosis can be largely ineffectual, and the mortality rate remains unacceptably high. Since Aspergillus fumigatus was first described almost 125 years ago, several other pathogenic species have been recognized. The marked biosynthetic abilities and varied mechanisms of gene recombination of aspergilli have long commanded attention in food technology and genetics. Their equally varied abilities to cause disease have attracted the interest of toxicologists, allergists and physicians concerned with infectious diseases.
FOREST ECOLOGY Authoritative resource covering traditional plant ecology topics and contemporary components such as climate change, invasive species, ecosystem services, and more Forest Ecology provides comprehensive coverage of the field, focusing on traditional plant ecology topics of tree structure and growth, regeneration, effects of light and temperature on tree physiology, forest communities, succession, and diversity. The work also reviews abiotic factors of light, temperature, physiography (landforms and topography), soil, and disturbance (especially fire), and provides coverage of ecosystem-level topics including carbon storage and balance, nutrient cycling, and forest ecosystem productivity. The 5th edition of Forest Ecology retains the readability and accessibility of the previous editions and includes important additional topical material that has surfaced in the field. All topics are approached with a landscape ecosystem or geo-ecological view, which places biota (organisms and communities) in context as integral parts of whole ecosystems that also include air (atmosphere and climate), topography, soil, and water. As such, the book fills a niche utilized by no other forest ecology text on the market, helping students and researchers consider whole ecosystems at multiple scales. Sample topics covered in Forest Ecology include: Contemporary components of forest ecology, including climate change, invasive species, diversity, ecological forestry, landscape ecology, and ecosystem services. Characteristics of physiography important for forest ecosystems, including its effects on microclimate, disturbance, soil, and vegetation. Genetic diversity of woody plants and genecological differentiation of tree species, including the importance of hybridization, polyploidy, and epigenetics. Site quality estimation using tree height and ground flora, and multiple-factor approaches to forest site and ecosystem classification and mapping. Forest Ecology is a highly accessible text for students, but it also serves as an excellent reference for academics. In addition, practitioners of forest ecology can also harness the information within to gain better insight into the field for practical application of concepts.
Proteins in living systems carry out a great variety of specific functions, each of which depends on the precise three-dimensional structure of a particular protein. Proteins are synthesized in the form of a flexible polypeptide chain that is capable of assuming a vast number of configurations; the transformation of this chain into a specific, relatively rigid three-dimensional structure is called folding--a remarkable process of self-organization. It is known that the amino acid sequences of some proteins have sufficient information to determine their three-dimensional structures. There are other proteins whose folding requires additional information beyond that found in the sequence of the mature protein. This book introduces the central problem of folding mechanisms as well as a number of other closely related issues. This book is neither a textbook nor a treatise. Rather, it is an attempt by several investigators to convey the excitement and challenges of those aspects of the folding problem in which they are actively engaged. The contributors give brief introductions to protein folding from the perspectives of molecular architecture, stability and dynamics, phage genetics, DNA exons, general physiology, and natural selection. They point out emerging new directions, including the suggestion of a class of diseases that result from protein folding defects.
This volume provides a comprehensive summary of developments in theories and techniques within the areas of sampling, measurement, and statistical methods for analyzing behavioral data. By unifying new theories, techniques, methodologies, terminology, and language in behavioral observation research, the authors provide a comprehensive source for students and researchers.
Over the Beach, written by historian and retired Army Colonel Donald W. Boose Jr., is the definitive history of the extensive but little known US Army amphibious operations during the Korean War, 1950-1953. Building on its extensive experience in World War II, the Army conducted three major landing operations during the war, including the assault at Inchon in September 1950. After the massive Chinese attacks two months later the Army executed a series of amphibious withdrawals as it fell back to more defensible positions farther down the peninsula. Throughout the war the Army also conducted a number of massive and complex over-the-shore logistical operations, as well as several amphibious special operations along the Korean littoral. Colonel Boose's work, commissioned by DAMO-ODG, Operations and Technology Office, provides the historical context for any subsequent amphibious operations on the Korean peninsula. As such, this thought-provoking study may provide insights to modern planners crafting future joint or combined operations in that part of the world. -- Publisher's Description.
The "Gold Standard" in Biochemistry text books, Biochemistry 4e, is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge.
Perhaps heartbreaking is the wrong word for a very happy event, one that brings tears to your eyes because you know what the alternative would have been. But however you describe it, the letters that Don Gazzaniga finds on his web site ever since his first cookbook was published easily bring tears to the reader's eyes. "The doctor told him that the very low-sodium diet is the main thing responsible for this success and I couldn't wait to share it with you." "When I said that your book saved [my husband's] life, I meant it." That first cookbook was a surprise to medical professionals and their patients alike. Doctors have always believed that no one could ever get below 1500 milligrams of sodium a daily diet. "Keep it at that level," Don's doctor told the sixty-three-year-old Gazzaniga in 1997. He had diagnosed his patient's problem as congestive heart failure and was about to sign him up for the only solution believed possible, a heart transplant. To Don, this was a challenge. After a lot of research, the help of nutritionist daughter, Jeannie, familiarity with the cuisines of many different countries, and hours in the kitchen, Don came up with a large selection of recipes and a twenty-eight-day menu that never went above five hundred milligrams of sodium a day! Yep! That's five hundred. And the food was delicious. The recipes in that first diet were gathered in a general cookbook that told readers just about everything they needed to know: where to find the right ingredients, how to make tasty substitutions that did not raise the sodium level, and more, with the sodium count given for each ingredient and each recipe. That was The No-Salt, Lowest-Sodium Cookbook. Don decided to embellish the general work with some specialties and, with his wife, Maureen, created The No-Salt, Lowest-Sodium Baking Book. If anyone thinks that you can't make delicious bread and pies and cookies and other baked goodies with very little or no sodium, try a few of Don's recipes. i0 But suppose you want to celebrate your grandson's third birthday, or your doctor's latest green light, with a party and need delicious tidbits for the guests. Here they are in their new book. Sometimes you feel like a light lunch---a salad, a sandwich, a bowl of soup. Here they are. There are sections explaining where to buy special flavorings and the like, how to substitute low-sodium or sodium-free ingredients, and a foreword by Dr. Michael Fowler, director of the Stanford Heart Transplant Program and medical director of the Stanford Cardiomyopathy Center.
Voet, Voet and Pratt's Fundamentals of Biochemistry, 5th Edition addresses the enormous advances in biochemistry, particularly in the areas of structural biology and Bioinformatics, by providing a solid biochemical foundation that is rooted in chemistry to prepare students for the scientific challenges of the future. While continuing in its tradition of presenting complete and balanced coverage that is clearly written and relevant to human health and disease, Fundamentals of Biochemistry, 5e includes new pedagogy and enhanced visuals that provide a pathway for student learning.
Voets Principles of Biochemistry, Global Edition addresses the enormous advances in biochemistry, particularly in the areas of structural biology and bioinformatics. It provides a solid biochemical foundation that is rooted in chemistry to prepare students for the scientific challenges of the future. New information related to advances in biochemistry and experimental approaches for studying complex systems are introduced. Notes on a variety of human diseases and pharmacological effectors have been expanded to reflect recent research findings. While continuing in its tradition of presenting complete and balanced coverage, this Global Edition includes new pedagogy and enhanced visuals that provide a clear pathway for student learning (4e de couverture).
The Domestic Assault of Women relates social and criminal justice policy to empirically tested social psychological theory about the causes and effects of wife assault. Donald G. Dutton argues that only by understanding the psychology of both the aggressors and the victims of wife assault can we generate informed social and criminal justice policy. By linking the psychological factors that support assaultive habits to police arrest policy and subsequent treatment, Dutton shows how police/therapist intervention can interrupt assaultive behaviour and prevent recidivism.
Biochemistry is a modern classic that had been thoroughly revised. Explains biochemical concepts while offering a unified presentation of life and its variation through evolution. Incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge. This edition has been updated to reflect the enormous advances in molecular and protein structure. Features a new chapter on nucleic acids, gene expression, and recombinant DNA technology, as well as a new chapter on nucleotide metabolism. Integrated Biochemical Interactions CD.
A scientifically based herbal and nutritional program to master stress, improve energy, prevent degenerative disease, and age gracefully • Explains how adaptogenic herbs work at the cellular level to enhance energy production and subdue the pro-inflammatory state behind degenerative disease • Explores the author’s custom adaptogenic blends for the immune system, cardiovascular health, thyroid function, brain health, and cancer treatment support • Provides more than 60 monographs on herbs and nutritional compounds based on more than 25 years of clinical practice with thousands of patients Weaving together the ancient wisdom of herbalism and the most up-to-date scientific research on cancer, aging, and nutrition, renowned medical herbalist and clinical nutritionist Donald Yance reveals how to master stress, improve energy levels, prevent degenerative disease, and age gracefully with the elite herbs known as adaptogens. Yance’s holistic approach, called the Eclectic Triphasic Medical System (ETMS), is based on extensive scientific research, more than 25 years of clinical practice, and excellent results with thousands of patients. It centers on four interconnected groups of health tools: botanical formulations, nutritional supplements, diet, and lifestyle. Defining three categories for adaptogenic herbs, he explains how formulations should combine herbs from each category to create a synergistic effect. He provides more than 60 monographs on herbs and nutritional compounds as well as custom combinations to revitalize the immune system, build cardiovascular health, protect brain function, manage weight, and support cancer treatment. He explains the interplay of endocrine health, the hypothalamic-pituitary-adrenal (HPA) axis, thyroid function, and stress in the aging process and reveals how adaptogenic treatment begins at the cellular level with the mitochondria--the microscopic energy producers present in every living cell. Emphasizing spirituality, exercise, and diet in addition to herbal treatments and nutritional supplements, Yance’s complete lifestyle program explores how to enhance energy production in the body and subdue the proinflammatory state that lays the groundwork for nearly every degenerative disease, taking you from merely surviving to thriving.
The "Gold Standard" in Biochemistry text books. Biochemistry 4e, is a modern classic that has been thoroughly revised. Don and Judy Voet explain biochemical concepts while offering a unified presentation of life and its variation through evolution. It incorporates both classical and current research to illustrate the historical source of much of our biochemical knowledge.
This book brings together information on the natural history, ecology and systematics of North American aquatic monocotyledons. The book is an overview of the biology of major aquatic species by compiling information from numerous sources that lie scattered among the primary literature, herbarium databases, and other reference sources. Information on more than 300 species in 87 genera of monocotyledons will be included. Recent phylogenetic analyses will be incorporated. Although focusing specifically on North America, the cosmopolitan distribution of many aquatic plants should make this an attractive text to people working virtually anywhere outside of the region as well. Key Selling Features: The primary source of natural history information on aquatic plants Comprehensive lists of ecological associates Synthetic overview of systematic relationships of aquatic species and genera Practical information for rare and invasive plant managers Essential guide to facilitate wetland delineation
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