The discovery of new molecules that function in neuronal communication can be viewed as a progression of steps beginning with the identification of the molecular structure, moving to the understanding of the mecha nisms mediating the synaptic action, and to the appraisal of the involve ment of the new molecules in various neuronal mechanisms, and finally reaching the evaluation of this molecule's role in brain function and the consequences that are triggered by its abnormalities. Enkephalins have followed such a pattern, and the present publication expresses the salient points of the last two phases in this succession. Enkephalins were discovered in December 1975; in addition to pain threshold regulation, their participation in other brain functions was soon ascertained. Perhaps, there are multiple recognition sites for multiple molecular forms of endogenous enkephalins; similarly to other transmitter recognition sites, these are coupled with ionic and nucleotide amplifying systems; thus, when activated, they can modify membrane funtion and ionic permeability of membranes. The present publication probes the current status of our knowledge concerning the consequences related to abnormalities in enkephalin storage, release, and synthesis. However, since our basic understanding of enkephalins is incomplete, the views reported should be considered to be in a state of flux.
Insightful study of principles of Wright's architecture. Over 120 photos, plans, and illustrations of Robie House, Fallingwater, Taliesin, other masterworks.
This volume addresses context from three comprehensive perspectives: first, its importance, the issues surrounding context, and its value in the laboratory and the field; second, the theory guiding the AI used to model its context; and third, its applications in the field (e.g., decision-making). This breadth poses a challenge. The book analyzes how the environment (context) influences human perception, cognition and action. While current books approach context narrowly, the major contribution of this book is to provide an in-depth review over a broad range of topics for a computational context no matter its breadth. The volume outlines numerous strategies and techniques from world-class scientists who have adapted their research to solve different problems with AI, in difficult environments and complex domains to address the many computational challenges posed by context. Context can be clear, uncertain or an illusion. Clear contexts: A father praising his child; a trip to the post office to buy stamps; a policewoman asking for identification. Uncertain contexts: A sneak attack; a surprise witness in a courtroom; a shout of "Fire! Fire!" Contexts as illusion: Humans fall prey to illusions that machines do not (Adelson’s checkerboard illusion versus a photometer). Determining context is not easy when disagreement exists, interpretations vary, or uncertainty reigns. Physicists like Einstein (relativity), Bekenstein (holographs) and Rovelli (universe) have written that reality is not what we commonly believe. Even outside of awareness, individuals act differently whether alone or in teams. Can computational context with AI adapt to clear and uncertain contexts, to change over time, and to individuals, machines or robots as well as to teams? If a program automatically "knows" the context that improves performance or decisions, does it matter whether context is clear, uncertain or illusory? Written and edited by world class leaders from across the field of autonomous systems research, this volume carefully considers the computational systems being constructed to determine context for individual agents or teams, the challenges they face, and the advances they expect for the science of context.
Frank Lloyd Wright : The Early Years : Progressivism : Aesthetics : Cities examines Wright's belief that all aspects of human life must embrace and celebrate an aesthetic experience that would thereby lead to necessary social reforms. Inherent in the theory was a belief that reform of nineteenth-century gluttony should include a contemporary interpretation of its material presence, its bulk and space, its architectural landscape. This book analyzes Wright's innovative, profound theory of architecture that drew upon geometry and notions of pure design and the indigenous as put into practice. It outlines the design methodology that he applied to domestic and non-domestic buildings and presents reasons for the recognition of two Wright Styles and a Wright School. The book also studies how his design method was applied to city planning and implications of historical and theoretical contexts of the period that surely influenced all of Wright's community and city planning.
Speculation abounds about the relationship between Frank Lloyd Wright and Ayn Rand. Was Wright the inspiration for Howard Roark, the architect hero of Rand's The Fountainhead? What can be made of their collaboration on the book's failed 1944 movie adaptation, and what can be gleaned from the 1949 Hollywood production of The Fountainhead? Where does the FBI--Wright was dubbed a communist sympathizer, and Rand was called before the House Un-American Activities Committee--fit into the story? Art, architecture, philosophy, film and politics come together in this exploration, which relies on the writings of Wright and Rand, FBI files, visual evidence and more to cement their connection. Chapters are devoted to Wright and Rand, the two together, their parts in both the failed production of The Fountainhead and the successful one, and the effect FBI harassment had on the movie and on their lives. Subsequent chapters discuss Wright's place as a Hollywood architect, and offer telling set designs and architectural images from the 1949 production of The Fountainhead. Several appendices supplement the illustrated text, and there is a filmography of movies mentioned in the book. A bibliography and index are also included.
During the years 1919 into 1925 Frank Lloyd Wright worked on four houses and a kindergarten located in metropolitan Los Angeles using concrete blocks as the main building material. The construction system has been described by Wright and others as ’uniquely molded’, ’woven like a textile fabric’ and perceived as ground breaking, truly modern, unprecedented. Many have attempted to uphold these claims while some thought the house-designs borrowed from old exotic buildings. For the first time this book brings together Wright’s declarations, the support of upholders and inferences in order to determine their accuracy and correctness, or the possibility of feigned or fictional stories. It examines technical developments of concrete blocks by Wright and others before his experiences in Los Angeles began in 1919. It also studies the manner of Wright’s design process by an examination of relevant pictorial and textual documents. A unique, in-depth and critical analysis of the houses is set within historical, biographical and theoretical contexts. Consequently, the book explains the impact upon Wright of California contemporaries, architects Irving Gill and Rudolph Schindler, and their instrumentally profound role upon the course of modernism 1907-1923. In doing so, it allows a full appreciation of Wright’s, Gill’s and Schindler’s buildings beyond their experiential qualities.
Design for Embedded Image Processing on FPGAs Bridge the gap between software and hardware with this foundational design reference Field-programmable gate arrays (FPGAs) are integrated circuits designed so that configuration can take place. Circuits of this kind play an integral role in processing images, with FPGAs increasingly embedded in digital cameras and other devices that produce visual data outputs for subsequent realization and compression. These uses of FPGAs require specific design processes designed to mediate smoothly between hardware and processing algorithm. Design for Embedded Image Processing on FPGAs provides a comprehensive overview of these processes and their applications in embedded image processing. Beginning with an overview of image processing and its core principles, this book discusses specific design and computation techniques, with a smooth progression from the foundations of the field to its advanced principles. Readers of the second edition of Design for Embedded Image Processing on FPGAs will also find: Detailed discussion of image processing techniques including point operations, histogram operations, linear transformations, and more New chapters covering Deep Learning algorithms and Image and Video Coding Example applications throughout to ground principles and demonstrate techniques Design for Embedded Image Processing on FPGAs is ideal for engineers and academics working in the field of Image Processing, as well as graduate students studying Embedded Systems Engineering, Image Processing, Digital Design, and related fields.
“A wonderfully readable account of Chicago’s early history” and the inspiration behind PBS’s American Experience (Michiko Kakutani, The New York Times). Depicting its turbulent beginnings to its current status as one of the world’s most dynamic cities, City of the Century tells the story of Chicago—and the story of America, writ small. From its many natural disasters, including the Great Fire of 1871 and several cholera epidemics, to its winner-take-all politics, dynamic business empires, breathtaking architecture, its diverse cultures, and its multitude of writers, journalists, and artists, Chicago’s story is violent, inspiring, passionate, and fascinating from the first page to the last. The winner of the prestigious Great Lakes Book Award, given to the year’s most outstanding books highlighting the American heartland, City of the Century has received consistent rave reviews since its publication in 1996, and was made into a six-hour film airing on PBS’s American Experience series. Written with energetic prose and exacting detail, it brings Chicago’s history to vivid life. “With City of the Century, Miller has written what will be judged as the great Chicago history.” —John Barron, Chicago Sun-Times “Brims with life, with people, surprise, and with stories.” —David McCullough, Pulitzer Prize–winning author of John Adams and Truman “An invaluable companion in my journey through Old Chicago.” —Erik Larson, New York Times–bestselling author of The Devil in the White City
This is a historical fiction novella about the Taino people before, during, and after the arrival of Columbus. It tells of Migua and Surani, a young Taino couple of Kiskeya (Hispaniola); and Anoki and Aiyana, a young Taino couple of Boriken (Puerto Rico) and the many adventures, dangers, and hardships they must face. It also tells of an affair between a young member of Columbus's crew and a Taino girl, and how their affair intertwines with Migua and Surani. The book also touches on the culture and history of the Taino, about whom we know so little.
Handsome pictorial essay documents creation of residential masterpiece with more than 160 interior and exterior photos, plans, elevations, sketches, and studies. Informative text recounts the house's history, including its site, plans, and construction.
Painstakingly researched and illuminating account of the making of the Fred C. Robie home. Revealing family documents, excerpts from a 1958 interview with Fred Robie, and 160 black-and-white illustrations.
Donald H. Stewart provides a comprehensive analysis of how the Republican press of the 1790s hastened the decline of the Federalist Party and promoted the election of Thomas Jefferson to the Presidency. Using both ridicule and serious argument, Republican editors of the decade attacked all aspects of Federalist foreign and domestic policies. Professor Stewart's examination of thousands of issues of more than 500 newspapers of the period enabled him to analyze the broad patterns of Republican opposition, the techniques used by the partisan editors, and the arguments that appeared most persuasive to the public. Many excerpts from these newspapers allow the reader to see how logical and emotional appeals were used in generating a groundswell of feeling against all things Federalist. In addition to the basic and well-known issues, a number of long-forgotten controversies and personalities are recalled to enhance understanding of the period. Professor Stewart concludes that, although the press alone was not responsible for Jefferson's elevation to the Presidency, he probably could not have been elected without the considerable number of newspapers that consistently supported and promulgated his views.
Fictional story based on the actual testimonies of colonists during the investigation of Dr. Andrew Turnbull's alleged abuses of his indentured servants in the ill-fated British colony established in 1768 at New Smyrna, Florida. Centers around a young Minorcan man and the girl he loves.
Al Rice awakens one morning with super psionic powers. While trying to find what happened to him, he learns that three groups of space aliens are observing Earth. Two groups are competing with each other for control of planet Earth. The third group sympathizes with Earth, however their own laws forbid them from any kind of interference with other cultures. Al tries to warn Earth, but his attempts are met with derision. He and a small group of UFO investigators are left with the impossible task of dealing with the powerful space alien forces. To make matters worse, one of the hostile groups has kidnapped and holding as hostage the girl that Al loves, while the other group has perfected a machine that nullifies Al's psionic powers.
For his critics and biographers, the 1930s have always been the most challenging period of Frank Lloyd Wright's career. This account uses the architect's long-inaccessable archives at Taliesin West to provide a balanced evaluation of Wright in the 1930s. It separates Wright's design activities from his self-promotion and places his philosophy of individualism within the context of the times.
Makers of 20th-Century Modern Architecture is an indispensable reference book for the scholar, student, architect or layman interested in the architects who initiated, developed, or advanced modern architecture. The book is amply illustrated and features the most prominent and influential people in 20th-century modernist architecture including Wright, Eisenman, Mies van der Rohe and Kahn. It describes the milieu in which they practiced their art and directs readers to information on the life and creative activities of these founding architects and their disciples. The profiles of individual architects include critical analysis of their major buildings and projects. Each profile is completed by a comprehensive bibliography.
Lavishly illustrated study recounts the turbulent history of one of Wright's most imaginative and controversial residential designs. More than 120 black-and-white images complement this perceptive account of the building's design and construction.
This profusely illustrated work offers abundant insights into the early development of the skyscraper and the influence of two master builders who played key roles in its evolution. Rare photos, floor plans, and renderings document such influential structures as Sullivan's Wainwright Building in St. Louis, Wright's Larkin building in Buffalo and many others.
Identification of Pathological Conditions in Human Skeletal Remains provides an integrated and comprehensive treatment of pathological conditions that affect the human skeleton. There is much that ancient skeletal remains can reveal to the modern orthopaedist, pathologist, forensic anthropologist, and radiologist about the skeletal manifestations of diseases that are rarely encountered in modern medical practice. Beautifully illustrated with over 1,100 photographs and drawings, this book provides essential text and materials on bone pathology, which will improve the diagnostic ability of those interested in human dry bone pathology. It also provides time depth to our understanding of the effect of disease on past human populations. - Comprehensive review of skeletal diseases encountered in archeological human remains - More than 1100 photographs and line drawings illustrating skeletal disease including both microscopic and gross features - Based on extensive research on skeletal paleopathology in many countries for over 35 years - Review of important theoretical issues in interpreting evidence of skeletal disease in archeological human populations
Eight tales of fantasy, a world of elves, space aliens, magic gone awry, mysterious beasts, a death curse, a stolen unicorn, a dream world, and a wand that belonged to Merlin
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