For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.
?xml version="1.0" encoding="utf-8"? text The Social Origins of the Welfare State traces the evolution of the first universal laws for Québec families, passed during the Second World War. In this translation of her award-winning Aux origines sociales de l ́État-providence, Dominique Marshall examines the connections between political initiatives and Québécois families, in particular the way family allowances and compulsory schooling primarily benefited teenage boys who worked on family farms and girls who stayed home to help with domestic labour. She demonstrates that, while the promises of a minimum of welfare and education for all were by no means completely fulfilled, the laws helped to uncover the existence of deep family poverty. Further, by exposing the problem of unequal access of children of different classes to schooling, these programs paved the way for education and funding reforms of the next generation. Another consequence was that in their equal treatment of both genders, the laws fostered the more egalitarian language of the war, which faded from other sectors of society, possibly laying groundwork for feminist claims of future decades. The way in which the poorest families influenced the creation of public, educational, and welfare institutions is a dimension of the welfare state unexamined until this book. At a time when the very idea of a universal welfare state is questioned, The Social Origins of the Welfare State considers the fundamental reasons behind its creation and brings to light new perspectives on its future.
For decades retroviruses have been riding the crest of a wave of experimental research directed toward the identification of an infectious agent of human neoplastic diseases. In the early 1970s, several scientists successfully demonstrated the presence of retroviruses in numerous animal species and proved their etiological role in some related diseases. Corresponding findings in humans were somewhat discouraging. Although financial support for this line· of research declined, a few dedicated retrovirologists survived and continued to collect more biological information and technological expertise that opened a new approach to the search for a human retrovirus. The rewards came with the discovery that the genes responsible for neoplastic transformation (oncogenes) are of cellular origin and can be shuttled about by retroviruses, and with the identification of a new family of Human T-cell Lymphotrophic retroViruses (HTLV) from patients with diseases ranging from leukemia to the acquired immunodeficiency syndrome (AIDS). An understanding of the role and significance of retroviruses in human pathology requires basic knowledge of the major animal systems studied. With this perspective in mind, we present here a survey that includes general overviews, minireviews on each animal system studied with selected experimental reports and, finally, a stimulating review of the field of human retrovirology by many of the pioneer scientists who created it. We are especially grateful to Profs. C. A. Romanzi and G. C. Schito for promoting the organization of the Symposium. On behalf of the Sym posium Committee, we thank E. Soeri, L. Casarino, G. P. Gesu, M.
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