Discovery Southeast's Books

African Researches

Or, Proceedings of the Association for Promoting the Discovery of the Interior Parts of Africa

By: Association for Promoting the Discovery of the Interior Parts of Africa

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African Researches

Or, Proceedings of the Association for Promoting the Discovery of the Interior Parts of Africa

By: Association for Promoting the Discovery of the Interior Parts of Africa

An 1802 work reporting on the exploits of explorers in Africa, including Mungo Park and Friedrich Hornemann.

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Page Count

461

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Cambridge University Press

Published Date

ISBN 10

1108032672

ISBN 13

9781108032674

Facing the Reality of Drug-Resistant Tuberculosis in India

Challenges and Potential Solutions: Summary of a Joint Workshop by the Institute of Medicine, the Indian National Science Academy, and the Indian Council of Medical Research

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

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Facing the Reality of Drug-Resistant Tuberculosis in India

Challenges and Potential Solutions: Summary of a Joint Workshop by the Institute of Medicine, the Indian National Science Academy, and the Indian Council of Medical Research

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

An estimated 8.8 million people fell ill with tuberculosis (TB) in 2010 and 1.4 million died from the disease. Although antibiotics to treat TB were developed in the 1950s and are effective against a majority of TB cases, resistance to these antibiotics has emerged over the years, resulting in the growing spread of multidrug-resistant (MDR) TB. Due to challenges in timely and accurate diagnosis of drug-resistant TB, length and tolerability of treatment regimens, and expense of second-line anti-TB drugs, effectively controlling the disease requires complex public health interventions. The IOM Forum on Drug Discovery, Development, and Translation held three international workshops to gather information from local experts around the world on the threat of drug resistant TB and how the challenges it presents can be met. Workshops were held in South Africa and Russia in 2010. The third workshop was held April 18-19, 2011, in New Delhi, India, in collaboration with the Indian National Science Academy and the Indian Council of Medical Research. The aim of the workshop was to highlight key challenges to controlling the spread of drug-resistant strains of TB in India and to discuss strategies for advancing and integrating local and international efforts to prevent and treat drug-resistant TB. This document summarizes the workshop.

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Page Count

186

Publisher

National Academies Press

Published Date

ISBN 10

0309219663

ISBN 13

9780309219662

Accelerating the Development of New Drugs and Diagnostics

Maximizing the Impact of the Cures Acceleration Network: Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

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Accelerating the Development of New Drugs and Diagnostics

Maximizing the Impact of the Cures Acceleration Network: Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

Advances in technologies and knowledge are creating new avenues for research and opportunities for the discovery and clinical development of innovative therapies and diagnostics. However, despite these opportunities, only a small fraction of investigational products are successfully developed into cures and therapies that can be accessed by patients. One response to the ever-widening gap between the number and promise of basic scientific discoveries and the translation of those discoveries into therapies is a renewed emphasis on collaborative approaches among federal agencies, academia, and industry, all directed at the advancement of the drug development enterprise. The newly developed Cures Acceleration Network (CAN)-a part of the National Center for Advancing Translational Sciences (NCATS) within the National Institutes of Health (NIH)-has the potential to catalyze widespread changes in NCATS, NIH, and the drug development ecosystem in general. On June 4-5, 2012, the IOM Forum on Drug Discovery, Development, and Translation held, at the request of NCATS, a workshop-bringing together members of federal government agencies, the private sector, academia, and advocacy groups-to explore options and opportunities in the implementation of CAN. Accelerating the Development of New Drugs and Diagnostics: Maximizing the Impact of the Cures Acceleration Network: Workshop Summary summarizes the workshop.

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108

Publisher

National Academies Press

Published Date

ISBN 10

0309261163

ISBN 13

9780309261166

Reptiles and Amphibians

By: Discovery Channel (Firm)

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Reptiles and Amphibians

By: Discovery Channel (Firm)

An Explore Your World Handbook.

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Page Count

196

Published Date

ISBN 10

1563318393

ISBN 13

9781563318399

The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS

Challenges and Opportunities: Summary of a Joint Workshop by the Institute of Medicine and the Institute of Microbiology, Chinese Academy of Sciences

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

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The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS

Challenges and Opportunities: Summary of a Joint Workshop by the Institute of Medicine and the Institute of Microbiology, Chinese Academy of Sciences

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

Multidrug-resistant tuberculosis (TB) is caused by bacteria resistant to isoniazid and rifampicin, the two most effective first-line anti-TB drugs, originally developed and introduced in the 1950 and 1960s. Since 2008, the Forum on Drug Discovery, Development, and Translation of the Institute of Medicine has hosted or co-hosted six domestic and international workshops addressing the global crisis of drug-resistant TB, with special attention to the BRICS countries - Brazil, Russia, India, China, and South Africa. The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS is the summary of a workshop convened to address the current status of drug-resistant TB globally and in China. This report considers lessons learned from high burden countries; highlights global challenges to controlling the spread of drug-resistant strains; and discusses innovative strategies to advance and harmonize local and international efforts to prevent and treat drug-resistant TB. Additionally, the report examines the problem of MDR TB and emergent TB strains that are potentially untreatable with drugs available and considers the critical leadership role of the BRICS countries in addressing the threats and opportunities in drug-resistant TB.

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Page Count

219

Publisher

National Academies Press

Published Date

ISBN 10

0309285968

ISBN 13

9780309285964

Our Daily Times with God

Favorite Selections from Our Daily Bread

By: Discovery House Publishers,Discovery House Staff,No Author,Dave Branon

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Our Daily Times with God

Favorite Selections from Our Daily Bread

By: Discovery House Publishers,Discovery House Staff,No Author,Dave Branon

Chioce daily devotionals from Our Daily Bread. Seven days of meditation for each of fifty-two different Old and New Testament events. Arranged by event to show God's involvement in human history-past, present and future

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436

Published Date

ISBN 10

0929239016

ISBN 13

9780929239019

Shark Week

Everything You Need to Know

By: Discovery,Martha Brockenbrough

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Shark Week

Everything You Need to Know

By: Discovery,Martha Brockenbrough

Tie-in to the Discovery Channel's popular program Shark Week.

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Page Count

162

Publisher

Macmillan

Published Date

ISBN 10

1250097770

ISBN 13

9781250097774

International Regulatory Harmonization Amid Globalization of Drug Development

Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

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International Regulatory Harmonization Amid Globalization of Drug Development

Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

The past several decades have been a time of rapid globalization in the development, manufacture, marketing, and distribution of medical products and technologies. Increasingly, research on the safety and effectiveness of new drugs is being conducted in countries with little experience in regulation of medical product development. Demand has been increasing for globally harmonized, science-based standards for the development and evaluation of the safety, quality, and efficacy of medical products. Consistency of such standards could improve the efficiency and clarity of the drug development and evaluation process and, ultimately, promote and enhance product quality and the public health. To explore the need and prospects for greater international regulatory harmonization for drug development, the IOM Forum on Drug Discovery, Development, and Translation hosted a workshop on February 13-14, 2013. Discussions at the workshop helped identify principles, potential approaches, and strategies to advance the development or evolution of more harmonized regulatory standards. This document summarizes the workshop.

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Page Count

129

Publisher

National Academies Press

Published Date

ISBN 10

0309284791

ISBN 13

9780309284790

Cash Cab

A Collection of the Best Trivia from the Hit Discovery Show

By: Discovery Communications

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Cash Cab

A Collection of the Best Trivia from the Hit Discovery Show

By: Discovery Communications

Enjoy the best, most challenging, and most popular questions from the hit Discovery show Cash Cab—and they're all no fare.The fast-paced, fact-driven, backseat game show fans can now play without hailing a taxi! This fun and engaging book features: • Organized for easy one-on-one read-along trivia, or game playing mode • Hundreds of multiple-choice questions that vary in degrees of difficulty for novice trivia buffs to frontseat know-it-alls • Popular "red-light challenges" and "shout-outs" • Page after page of trivia sidebars and fascinating facts • Cash Cab host Ben Bailey's favorite places to visit in New York

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242

Publisher

Penguin

Published Date

ISBN 10

1101576847

ISBN 13

9781101576847

Breakthrough Business Models

Drug Development for Rare and Neglected Diseases and Individualized Therapies: Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation,Robert Giffin,Sally Robinson,Theresa Wizemann

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Breakthrough Business Models

Drug Development for Rare and Neglected Diseases and Individualized Therapies: Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation,Robert Giffin,Sally Robinson,Theresa Wizemann

The process for developing new drug and biologic products is extraordinarily expensive and time-consuming. Although large pharmaceutical companies may be able to afford the cost of development because they can expect a large return on investment, organizations developing drugs to treat rare and neglected diseases are unable to rely on such returns. On June 23, 2008, the Institute of Medicine's Forum on Drug Discovery, Development, and Translation held a public workshop, "Breakthrough Business Models: Drug Development for Rare and Neglected Diseases and Individualized Therapies," which sought to explore new and innovative strategies for developing drugs for rare and neglected diseases.

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151

Publisher

National Academies Press

Published Date

ISBN 10

0309178169

ISBN 13

9780309178167

Public Engagement and Clinical Trials

New Models and Disruptive Technologies: Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

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Public Engagement and Clinical Trials

New Models and Disruptive Technologies: Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

Clinical trials provide essential information needed to turn basic medical research findings into patient treatments. New treatments must be studied in large numbers of humans to find out whether they are effective and to assess any harm that may arise from treatment. There is growing recognition among many stakeholders that the U.S. clinical trials enterprise is unable to keep pace with the national demand for research results. The IOM, along with the Mount Sinai School of Medicine, held a workshop June 27-28, 2011, to engage stakeholders and experts in a discussion about possible solutions to improve public engagement in clinical trials.

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140

Publisher

National Academies Press

Published Date

ISBN 10

0309219299

ISBN 13

9780309219297

Rapid Medical Countermeasure Response to Infectious Diseases

Enabling Sustainable Capabilities Through Ongoing Public- and Private-Sector Partnerships: Workshop Summary

By: National Academies of Sciences, Engineering, and Medicine,Institute of Medicine,Board on Global Health,Board on Health Sciences Policy,Forum on Microbial Threats,Forum on Drug Discovery, Development, and Translation,Forum on Medical and Public Health Preparedness for Catastrophic Events

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Rapid Medical Countermeasure Response to Infectious Diseases

Enabling Sustainable Capabilities Through Ongoing Public- and Private-Sector Partnerships: Workshop Summary

Emerging infectious disease threats that may not have available treatments or vaccines can directly affect the security of the world's health since these diseases also know no boundaries and will easily cross borders. Sustaining public and private investment in the development of medical countermeasures (MCMs) before an emerging infectious disease becomes a public health emergency in the United States has been extremely challenging. Interest and momentum peak during a crisis and wane between events, and there is little interest in disease threats outside the United States until they impact people stateside. On March 26 and 27, 2015, the Institute of Medicine convened a workshop in Washington, DC to discuss how to achieve rapid and nimble MCM capability for new and emerging threats. Public- and private-sector stakeholders examined recent efforts to prepare for and respond to outbreaks of Ebola Virus Disease, pandemic influenza, and coronaviruses from policy, budget, and operational standpoints. Participants discussed the need for rapid access to MCM to ensure national security and considered strategies and business models that could enhance stakeholder interest and investment in sustainable response capabilities. This report summarizes the presentations and discussions from this workshop.

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Page Count

177

Publisher

National Academies Press

Published Date

ISBN 10

0309378648

ISBN 13

9780309378642

Envisioning a Transformed Clinical Trials Enterprise in the United States

Establishing an Agenda for 2020: Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

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Envisioning a Transformed Clinical Trials Enterprise in the United States

Establishing an Agenda for 2020: Workshop Summary

By: Institute of Medicine,Board on Health Sciences Policy,Forum on Drug Discovery, Development, and Translation

There is growing recognition that the United States' clinical trials enterprise (CTE) faces great challenges. There is a gap between what is desired - where medical care is provided solely based on high quality evidence - and the reality - where there is limited capacity to generate timely and practical evidence for drug development and to support medical treatment decisions. With the need for transforming the CTE in the U.S. becoming more pressing, the IOM Forum on Drug Discovery, Development, and Translation held a two-day workshop in November 2011, bringing together leaders in research and health care. The workshop focused on how to transform the CTE and discussed a vision to make the enterprise more efficient, effective, and fully integrated into the health care system. Key issue areas addressed at the workshop included: the development of a robust clinical trials workforce, the alignment of cultural and financial incentives for clinical trials, and the creation of a sustainable infrastructure to support a transformed CTE. This document summarizes the workshop.

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Page Count

248

Publisher

National Academies Press

Published Date

ISBN 10

0309253152

ISBN 13

9780309253154

Insight Guide: Puerto Rico

By: Insight Guides,Barbara Balletto,Discovery Channel

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Insight Guide: Puerto Rico

By: Insight Guides,Barbara Balletto,Discovery Channel

A travel series unlike any other, Insight Guides go beyond the sights and into reality. Their incomparable photojournalistic approach captures the uniqueness of each culture they cover: their traditions, their arts, their history, their lives. The stunning photography is married to compelling text, written by local writers; the people most qualified to convey their culture's "secrets". Yes, Insight Guides will tell you which attractions to visit, but they'll also tell you a whole lot more. From the most popular resort cities to the world's most remote and exotic villages, Insight Guides will give you the insider's perspective you need to truly experience any destination you visit. Insight Guides serve many purposes. They are ideal for planning a trip. And, they're wonderful souvenirs to treasure for years after. Even the armchair traveler can be swept away by their magnificent content and experience the world from the comfort of home. Many international and domestic and domestic destinations also offer companion FlexiMaps, an innovative laminated folding map specially designed for the discriminating traveler.

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Page Count

300

Publisher

Langenscheidt Publishers

Published Date

ISBN 10

0887291783

ISBN 13

9780887291784

Animal Planet The Most Extreme Bugs

By: Discovery Channel

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Animal Planet The Most Extreme Bugs

By: Discovery Channel

Discusses some of the wildest, craziest bugs in some crazy categories.

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John Wiley & Sons

Published Date

ISBN 10

0787986631

ISBN 13

9780787986636

Book's by Discovery Southeast

African Researches

African Researches

Facing the Reality of Drug-Resistant Tuberculosis in India

Facing the Reality of Drug-Resistant Tuberculosis in India

Accelerating the Development of New Drugs and Diagnostics

Accelerating the Development of New Drugs and Diagnostics

Reptiles and Amphibians

Reptiles and Amphibians

The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS

The Global Crisis of Drug-Resistant Tuberculosis and Leadership of China and the BRICS

Our Daily Times with God

Our Daily Times with God

Shark Week

Shark Week

International Regulatory Harmonization Amid Globalization of Drug Development

International Regulatory Harmonization Amid Globalization of Drug Development

Cash Cab

Cash Cab

Breakthrough Business Models

Breakthrough Business Models

Public Engagement and Clinical Trials

Public Engagement and Clinical Trials

Rapid Medical Countermeasure Response to Infectious Diseases

Rapid Medical Countermeasure Response to Infectious Diseases

Envisioning a Transformed Clinical Trials Enterprise in the United States

Envisioning a Transformed Clinical Trials Enterprise in the United States

Insight Guide: Puerto Rico

Insight Guide: Puerto Rico

Animal Planet The Most Extreme Bugs

Animal Planet The Most Extreme Bugs

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