Environmental Organic Chemistry focuses on environmental factors that govern the processes that determine the fate of organic chemicals in natural and engineered systems. The information discovered is then applied to quantitatively assessing the environmental behaviour of organic chemicals. Now in its 2nd edition this book takes a more holistic view on physical-chemical properties of organic compounds. It includes new topics that address aspects of gas/solid partitioning, bioaccumulation, and transformations in the atmosphere. Structures chapters into basic and sophisticated sections Contains illustrative examples, problems and case studies Examines the fundamental aspects of organic, physical and inorganic chemistry - applied to environmentally relevant problems Addresses problems and case studies in one volume
Hepatology -- a systematic overview The 1st edition was sold out within one year and a reprint became necessary. The 2nd edition has been updated, revised and extended to include some 900 pages. Unique - 477 top-quality coloured figures containing clinical and immunological findings, laparoscopic and and histologic features as well as imaging procedures - all figures directly integrated in the respective text; this results in a new form of learning from "seeing" to "understanding" Attractive - 306 tables in colour - coloured highlighting of important principles and statements for better reading - well-structured and systematic approaches support the content - derived from clinical hepatology for practical use by specialists and in hospital Instructive - detailed presentation of morphology and its integration in liver disease - precise recommendations for therapy and summarized descriptions of special forms of treatment (inlcuding a separate chapter on "Therapy" Manual - about 7,000 references are listed in full; quotations of significant historical publications - first authors of therapy procedures, methods, medical techniques and invasive measures are given as far as possible - comprehensive subject index and register of abbreviations
The completion of the Human Genome Project and the rapid progress in cell bi- ogy and biochemical engineering, are major forces driving the steady increase of approved biotech products, especially biopharmaceuticals, in the market. Today mammalian cell products (“products from cells”), primarily monoclonals, cytokines, recombinant glycoproteins, and, increasingly, vaccines, dominate the biopharmaceutical industry. Moreover, a small number of products consisting of in vitro cultivated cells (“cells as product”) for regenerative medicine have also been introduced in the market. Their efficient production requires comprehensive knowledge of biological as well as biochemical mammalian cell culture fundamentals (e.g., cell characteristics and metabolism, cell line establishment, culture medium optimization) and related engineering principles (e.g., bioreactor design, process scale-up and optimization). In addition, new developments focusing on cell line development, animal-free c- ture media, disposables and the implications of changing processes (multi-purpo- facilities) have to be taken into account. While a number of excellent books treating the basic methods and applications of mammalian cell culture technology have been published, only little attention has been afforded to their engineering aspects. The aim of this book is to make a contribution to closing this gap; it particularly focuses on the interactions between biological and biochemical and engineering principles in processes derived from cell cultures. It is not intended to give a c- prehensive overview of the literature. This has been done extensively elsewhere.
This mini-encyclopedia contains more than 1,500 alphabetical entries from the entire field of peptide science in one handy volume, as well as the technical terms, acronyms and concepts used in peptide chemistry. It also features the complete sequence of more than 800 peptides, numerous illustrations and numerous cross-references. Areas covered include: - biological peptides and small proteins - peptide hormones - pharmaceutical peptides - peptide antibiotics - peptide inhibitors - peptide reagents - peptide tags - structural classes - synthesis and purification - analytical methods - proteomics and peptidomics. Condensed yet accessible, only essential information is displayed, extensively linked via references to the recent scientific literature for further study.
Der "Sewald/Jakubke" ist und bleibt das einzige moderne, auf dem neuesten wissenschaftlichen Stand gehaltene fortgeschrittene Lehrbuch der Peptid-Biochemie! Auch für diese zweite, um ein Viertel erweitere Auflage haben die Autoren Hunderte von Publikationen gelesen und zu einem informativen und vollständigen Überblick über das Fachgebiet zusammengefasst. Nach einer Einführung in die Grundlagen der Peptidstruktur und -synthese werden die wichtigsten Familien biologisch aktiver Peptide systematisch abgehandelt. Mit interdisziplinärem Anspruch werden dann wichtige Anwendungen aus der Biotechnologie, Pharmazie und Biomedizin besprochen. Selbstverständlich werden auch Themen der Spitzenforschung berücksichtigt, zum Beispiel Pseudopeptide, Peptidmimetika und Aspekte der kombinatorischen Synthese. -- Neu in dieser Auflage sind Fragen und Übungsaufgaben, die das Nacharbeiten von Vorlesungen oder das Selbststudium erleichtern.
The rapid growth of the world population - nearly six-fold over the last hundred years - combined with the rising number of technical installations especially in the industrialized countries has lead to ever tighter and more strained living spaces on our planet. Because ofthe inevitable processes oflife, man was at first an exploiter rather than a careful preserver of the environment. Environmental awareness with the intention to conserve the environment has grown only in the last few decades. Environmental standards have been defined and limit values have been set largely guided, however, by scientific and medical data on single exposures, while public opinion, on the other hand, now increasingly calls for astronger consideration of the more complex situations following combined exposures. Furthermore, it turned out that environmental standards, while necessarily based on scientific data, must also take into account ethical, legal, economic, and sociological aspects. A task of such complexity can only be dealt with appropriately in the framework of an inter disciplinary group.
The present Supplement Volume Beryllium A 3 continues and completes the description of the physical properties of the element, begun in Supplement Volume A 2, 1991, and also treats the electrochemical behavior of the metal. The unique combination of the Be properties, which was pointed out in Supplement Volume A 2, is also demonstrated in the following chapters of this Volume A 3: 13. Electrical Properties 14. Electronic Properties 15. Optical Properties. Emission and Impact Phenomena 16. Electrochemical Behavior Starting with the electrical properties, Be isarather good electrical conductor in centrast to what might be expected. Superconductivity was studied, especially on films. Quantum effects, which are more pronounced in Be than in most other metals, are the reason for numerous in vestigations of the magnetoresistance and the magnetic-breakdown effect. The basis for many of the characteristic properties is the unique nature of bonding in Be as a consequence of its peculiar electronic structure and the special shape of its Fermi surface which also gave rise to further numerous studies. Detailed cluster calculations were per formed to better understand the bonding in the metal. Regarding the optical properties, the high reflectivity of Be, particularly in the infrared region, makes it attractive for the fabrication of precision optical surfaces (mirrors); it is also useful for solar-collector surfaces in spacecraft applications. Emission and electron-and ion impact phenomena as well as neutron optics are also discussed.
You are out of your minds!" That was the reaction of many when they heard. Klaus and Martina John were planning to build a modern hospital for the Peruvian Indios - without any capital, income, or loans. But the resulting story of Diospi Suyana has become a thriller full of miracles and examples of divine providence. Since its inauguration in 2007, the adventure has continued as Diospi Suyana has regularly faced danger, corruption, and seemingly insurmountable obstacles. And yet it continues to grow. The Hospital of Hope has been the subject of 500+ media reports around the world. The unexpected twists and turns in its history has fascinated millions.
This fourth volume of the Supplement Series supplying the Main Volumes of the series "Perfluorohalogenoorgano Compounds of Main Group Elements" (Part 1 to 9) covers the heterocyclic compounds of nitrogen as the last main group element of this series. Compounds of the elements of main group 1 to 4, 6 (without 0), and of P, As, Sb, Bi, and I are presented in the Supplement Volumes 1 to 3. Concept, organization, and selection as to coverage of the material are the same as in the preceeding volumes. Title compounds are either newly synthesized ones or those compounds already referred in the Main Volume Parts 5 and 6 for which new facts have been published. I wish to thank Prof. Dr. Dr. h. c. E. Fluck and his co-workers for their excellent cooperation and many colleagues for providing reprints and patents. One of us (U. Niemann) thanks Philips GmbH Forschungslaboratorium Aachen for generous support. November 1987 Bochum, A. Haas x Table of Contents Page 1 Three-Membered Perfluorohalogenoorgano Nitrogen Heterocycles 1-1 Formation and Preparation . . . . . . . . . . . 1-1.1 Three-Membered Heterocycles with One N Atom.
Dieter Schlesak's haunting novel The Druggist of Auschwitz—beautifully translated from the German by John Hargraves—is a frighteningly vivid portrayal of the Holocaust as seen through the eyes of criminal and victim alike. Adam, known as "the last Jew of Schäßburg," recounts with disturbing clarity his imprisonment at the infamous Auschwitz concentration camp. Through Adam's fictional narrative and excerpts of actual testimony from the Frankfurt Auschwitz Trial of 1963–65, we come to learn of the true-life story of Dr. Victor Capesius, who, despite strong friendships with Jews before the war, quickly aided in and profited from their tragedy once the Nazis came to power. Interspersed with historical research and the author's face-to-face interviews with survivors, the novel follows Capesius from his assignment as the "sorter" of new arrivals at Auschwitz—deciding who will go directly to the gas chamber and who will be used for labor—through his life of lavish wealth after the war to his arrest and eventual trial. Schlesak's seamless incorporation of factual data and testimony—woven into Adam's dreamlike remembrance of a world turned upside down—makes The Druggist of Auschwitz a vital and unique addition to our understanding of the Holocaust.
Johann Christoph Blumhardt (1805-1880) was a pastoral counselor and theologian of hope. His theology and pastoral approach, shaped as they were by the awakening in his congregation and numerous incidents of faith healing, provoked earnest and lively debate, and the controversy continues today. Ising's work mines the original sources, the product of an interaction with Blumhardt's life and work that goes back many years. He has drawn a portrait that explores the shadows as well as its bright side. Readers are invited to enter fully into the nineteenth century, Blumhardt's century, yet are constantly reminded that the problems of that day have lost none of their currency within the altered mental horizons of today.
This book presents the physical concepts and tools to characterize and describe the formation of metastable solids from undercooled melts. Its aim is to facilitate understanding of the development of the science and technology of solidification of melts and to introduce new concepts within this exciting research field in order to fulfil the challenges of the future in the field of undercooled melts. A comprehensive description of the science and applications of the undercooling phenomenon is given. It is composed of several main parts: experimental techniques for undercooling; characterization of the undercooled melt as the first step in rapid solidification; introducing the concepts of modern theories of rapid dendrite and eutectic growth and their comparison with experimental results, and a survey of metastable materials formed from the non-equilibrium state of an undercooled melt.* Showing clear links to possible application of results obtained from basic research * The subject matter is multidisciplinary and will be of interest to material scientists, physicists, physical chemists, mechanical and electrical engineers
Boltzmann's formula S = In[W(E)] defines the microcanonical ensemble. The usual textbooks on statistical mechanics start with the microensemble but rather quickly switch to the canonical ensemble introduced by Gibbs. This has the main advantage of easier analytical calculations, but there is a price to pay — for example, phase transitions can only be defined in the thermodynamic limit of infinite system size. The question how phase transitions show up from systems with, say, 100 particles with an increasing number towards the bulk can only be answered when one finds a way to define and classify phase transitions in small systems. This is all possible within Boltzmann's original definition of the microcanonical ensemble.Starting from Boltzmann's formula, the book formulates the microcanonical thermodynamics entirely within the frame of mechanics. This way the thermodynamic limit is avoided and the formalism applies to small as well to other nonextensive systems like gravitational ones. Phase transitions of first order, continuous transitions, critical lines and multicritical points can be unambiguously defined by the curvature of the entropy S(E,N). Special attention is given to the fragmentation of nuclei and atomic clusters as a peculiar phase transition of small systems controlled, among others, by angular momentum.The dependence of the liquid-gas transition of small atomic clusters under prescribed pressure is treated. Thus the analogue to the bulk transition can be studied. The book also describes the microcanonical statistics of the collapse of a self-gravitating system under large angular momentum.
This classic of modern theoretical physics is the first and only comprehensive treatment of the superfluid phases of helium 3, a crucial aspect of condensed matter physics with applications to many other fields. The self-contained approach explores ideas, concepts, and theoretical results, emphasizing symmetries and the consequences of their spontaneous breakdown. 1990 edition.
Written by experienced authors, this book presents numerous natural everyday products with a high range of structural diversity. Twenty natural products have been arranged in five sections, describing three alkaloids, five colored compounds, three carbohydrates and glycosides, seven terpenoids, and two aromatic compounds. Adopting a highly didactical approach, each chapter features a uniform structure: Background, in-depth information about isolation processes and structural characterization as well as a Q&A section at the end. Alongside the theoretical information many practical hints for the laboratory work are also included. A comprehensive overview of UV-, IR- and NMR-spectroscopy as well as mass-spectrometry for every exemplified compound is provided and the understanding of these methods is supported by concluding questions and exercises. Educating and entertaining, this full-color textbook turns the learning process into a real pleasure, not only for students in natural products chemistry but also experienced professionals.
The Nature of Language addresses one of the most fundamental questions of mankind: how did language evolve, and what are the neurobiological and cognitive foundations of language processing? These questions are explored from different perspectives to discuss the building blocks of language evolution and how they developed in the way they can be found in modern humans. Primarily, neural mapping methods of cognition presented in this research provide extremely valuable data about the neural circuitries that are involved in language processing. Thus, the book explores and illustrates cortical mapping in typical language patterns, but also cortical mapping in atypical populations that fail to process particular language aspects. A neurobiological stance is used to inquire about how language abilities of our species evolved to communicate for the purposes of conveying information such as ideas, emotions, goals, and humor. The evolutionary language model presented builds on the cognitive abilities of our ancestors, and it allows readers to draw a variety of expansive conclusions from that, including the idea that human language as an interface system provides the basis for consciousness.
Surface Scattering Experiments with Conduction Electrons shows how this process can be used to investigate surface processes of thin metal films. Since a thin film is in one direction of a size comparable to the mean free path of the conduction electrons, such a film is both substrate and sensor and must be characterized by other surface-analytical methodsas demonstrated here. Also discussed is how the dc-resistivity measurement permits the study of surface processes such as adsorption, desorption, and surface diffusion up to crystalline growth. The in situ observation of epitaxial growth is additionally shown to be possible. Thus the electronic structure of superimposed metal films and superlattices can be elucidated. This is an essential topic for all surface physicists.
Beryllium Supplement Volume A2 describes the properties of the bulk metal, the main emphasis being on the crystallographic structure and the structure-related (mechanical) properties. The great importance of this metal, for instance in nuclear and space technologies, results from its unique combination of properties, i.e., low density, extremely high elasticity modulus, and relatively high melting point. In addition, Be played a particular role in studying the fundamental mechanisms of deformation in the lattices of metals. On this basis, numerous factors contributing to the ductility or brittleness of Be are discussed. Thermal and magnetic properties complete the description of Be in this volume.
Today’s Comprehensive and Authoritative Guide to Augmented Reality By overlaying computer-generated information on the real world, augmented reality (AR) amplifies human perception and cognition in remarkable ways. Working in this fast-growing field requires knowledge of multiple disciplines, including computer vision, computer graphics, and human-computer interaction. Augmented Reality: Principles and Practice integrates all this knowledge into a single-source reference, presenting today’s most significant work with scrupulous accuracy. Pioneering researchers Dieter Schmalstieg and Tobias Höllerer carefully balance principles and practice, illuminating AR from technical, methodological, and user perspectives. Coverage includes Displays: head-mounted, handheld, projective, auditory, and haptic Tracking/sensing, including physical principles, sensor fusion, and real-time computer vision Calibration/registration, ensuring repeatable, accurate, coherent behavior Seamless blending of real and virtual objects Visualization to enhance intuitive understanding Interaction–from situated browsing to full 3D interaction Modeling new geometric content Authoring AR presentations and databases Architecting AR systems with real-time, multimedia, and distributed elements This guide is indispensable for anyone interested in AR, including developers, engineers, students, instructors, researchers, and serious hobbyists.
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