This book describes biosynthetic methods to synthesize heterocycliccompounds, offering a guide for the development of new drugs basedon natural products. The authors explain the role of naturalproducts in chemistry and their formation along with importantanalytical methods and techniques for working withheterocycles. • Covers methods and techniques: isotopic labelling,enzymes and mutants, and pathway identification • Provides a thorough resource of informationspecifically on heterocyclic natural products and their practicalbiosynthetic relevance • Explains the role of natural products in chemistry andtheir formation • Discusses gene cluster identification and the use ofbiogenetic engineering in pharmaceutical application
The challenge of connecting employers and educators to collaboratively plan for training future workers is an enduring one-particularly for jobs that are rapidly changing because of technological advancements. This report addresses this challenge as it pertains to employers and educators in the oil and natural gas industry located in and around the Utica and Marcellus shales. The combination of horizontal drilling and hydraulic fracturing to tap natural gas has resulted in the Utica and Marcellus shales becoming major sources of natural gas supply within the United States and are predicted to bring significant long-term economic benefits to the tristate region of Ohio, Pennsylvania, and West Virginia. To inform policy decisions on how best to expand and sustain the pool of workers with knowledge and skills needed by oil and natural gas employers in the tristate region, this report summarizes the findings from surveys administered to the region's oil and gas employers and education providers. We found that basic cross-cutting skills-such as time management, speaking, and writing-and knowledge of business operations (including sales and marketing) are reported by employers as essential for their workers to competently perform in high-priority occupations. However, these basic skills tend not to be emphasized in local postsecondary degree programs that support the oil and natural gas industry. We also found a clear lack of collaboration and partnerships between oil and gas companies and education providers across the region, with colleges and employers each pointing to the other's unwillingness as the source for lack of partnerships or collaboration.
The authors describe an unconstrained ?clean sheet? approach to space acquisition for the U.S. Space Force designed around the unique mission and calling of the new service.
The U.S. Air Force has embarked on a new round of strategic planning, under the auspices of its 2015 Strategic Master Plan (SMP), to help set the future direction of the service. Refining the Air Force's strategic planning process may help the service align itself to its environment and keep key initiatives on track. To offer the Air Force actionable findings on strategic planning, we surveyed a number of major topics and literatures for common themes and findings. The basic concept and approach of the SMP has promise. Our review of history and theory supports the idea that a consistent, ongoing planning structure would offer important advantages to any military service. Yet we also found that the actual design and execution of the SMP could potentially obstruct, rather than facilitate, these objectives. The SMP retains many elements of an old-style strategic planning process — forecasting an identifiable future, building an exhaustive, pre-set plan, and identifying hundreds of specific tasks — which creates a focus on execution over creative and flexible responses."--Publisher's description.
DIANA PALMER COLLECTED BOOKS 1-6 New York Times bestselling author Diana Palmer brings you six dangerous, ruthless men - and the women who can tame them...
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