WHEN YOUR LIFE IS LIKE A CIRCUS"....and whose life isn't? Here's the story of a family of entertainers with 48 years of real life experiences of international entertainment in circuses and stage productions that included hanging from a helicopter while strapped in a straightjacket! Brushes with death from rogue elephants, traveling hundreds of "mountain miles" a day, and meeting strangers who turned out to be 'angels' who showed up at "just the right time" are all integral parts of this exciting testimony of a family who felt God was directing their paths and who learned how to listen to His directions as they enjoyed His blessings along the way. This book contains the story of an entire family who took their God given talents and developed programs to motivate "children of all ages" to be the very best they were created to be! It's a true life story that can inspire the reader with the motivation to get thru challenges as THEY listen to God's direction in THEIR personal lives encouraging everyone to "MAKE CHRIST THEIR RINGMASTER"!
Tate provides a detailed account of 'subjective authenticity' in German literature: its origins in the 1930s' exile debates, its evolution during the GDR's lifespan, and its manifestations in the work of five East German authors: Brigitte Reinmann, Franz Fühmann, Stefan Heym, Günter de Bruyn and Christa Wolf.
A new global focus, new editorial team, and new content make Principles and Practice of Gynecologic Oncology, 7th Edition an invaluable resource for practitioners, researchers, and students who need an authoritative reference for understanding and treating gynecologic cancers. This edition maintains the practical, multidisciplinary approach that encompasses surgery, medical oncology, radiation oncology, and pathology, reflecting the many recent advances in each area.
Several South African agencies, institutes, organizations, and professional bodies are promoting and developing contact-center operations in order to satisfy international and national market demands. Accordingly, additional information, knowledge, and experience are needed to improve on how organizations integrate core business processes into these contact-centers. Responding to this need, the industry is now being represented in higher education. Featuring sections on managing contact-center performance, recruiting, training, and motivating staff- and customer-relations management, this comprehensive course guide, cowritten by several experts in the field, is ideal for institutions offering courses for contact-center agents and anyone working in the contact-center industry.
Statistics is the activity of inferring results about a population given a sample. Historically, statistics books assume an underlying distribution to the data (typically, the normal distribution) and derive results under that assumption. Unfortunately, in real life, one cannot normally be sure of the underlying distribution. For that reason, this book presents a distribution-independent approach to statistics based on a simple computational counting idea called resampling. This book explains the basic concepts of resampling, then systematically presents the standard statistical measures along with programs (in the language Python) to calculate them using resampling, and finally illustrates the use of the measures and programs in a case study. The text uses junior high school algebra and many examples to explain the concepts. The ideal reader has mastered at least elementary mathematics, likes to think procedurally, and is comfortable with computers. Table of Contents: The Basic Idea / Bias Corrected Confidence Intervals / Pragmatic Considerations When Using Resampling / Terminology / The Essential Stats / Case Study: New Mexico's 2004 Presidential Ballots / References
Starving Cancer Cells: Evidence-Based Strategies to Slow Cancer Progression — A Selection of Readings for Health Services Providers presents an edited and annotated collection of recent medical journal publications and abstracts illustrating new approaches to treatment derived from the metabolic theory of cancer. It intends to shed an early light on a relatively new approach to our understanding of the cancer cell idiosyncratic metabolic dysfunction, and on evidence-based new treatment strategies derived from that understanding. The book discusses topics such as tumor starvation by L-arginine deprivation; L-canavanine depriving tumors of L-arginine in pancreatic, multiple myeloma and breast cancer; glucose deprivation and intermittent fasting; glutamine uptake in cancer; the relation of oxygen-starved cancer cells with aspartate; and reducing tolerance of tumor cells to nutrition starvation. The content is presented in a contextualized and practical way in order to facilitate the transition from bench to bedside. This is a valuable resource for practitioners, oncologists and other members of healthcare chain who are interested in learning more about the most recent tumor cell starvation strategies and how they can improve overall treatment outcome. - Provides extensive comments on scientific publications detailing recent findings about tumor cell auxotrophy applied to tumor cell starvation strategies - Helps the reader to find relevant and practical information on cancer cell starvation, otherwise spread through niched specialized journals, in one single place - Comments on the recent findings putting them in context of clinical practice in order to provide the reader with means of translating high level research to the clinics
This book is for students and researchers who have had a first year graduate level mathematical statistics course. It covers classical likelihood, Bayesian, and permutation inference; an introduction to basic asymptotic distribution theory; and modern topics like M-estimation, the jackknife, and the bootstrap. R code is woven throughout the text, and there are a large number of examples and problems. An important goal has been to make the topics accessible to a wide audience, with little overt reliance on measure theory. A typical semester course consists of Chapters 1-6 (likelihood-based estimation and testing, Bayesian inference, basic asymptotic results) plus selections from M-estimation and related testing and resampling methodology. Dennis Boos and Len Stefanski are professors in the Department of Statistics at North Carolina State. Their research has been eclectic, often with a robustness angle, although Stefanski is also known for research concentrated on measurement error, including a co-authored book on non-linear measurement error models. In recent years the authors have jointly worked on variable selection methods.
Nickel and Chromium Plating, Second Edition, does not merely update the first edition but also places additional emphasis on certain methods that have achieved increased industrial use in the 14 years since the first edition was published. The book begins by tracing the history of nickel and chromium plating. This is followed by a discussion of the electrochemistry of electrodeposition from aqueous electrolyte solutions. Separate chapters cover topics such as autocatalytic (electroless) nickel deposition; nickel plating onto aluminum and other difficult substrates; plating onto plastics and high-speed plating; the deposition of various nickel alloys for decorative and functional applications; composite coatings; and tampon (brush) plating. This book will be helpful to those new to the plating industry; those experienced in the industry will find that this revised version enables them to keep up-to-date with the latest developments in this specialized technology.
With characteristic boldness and careful reassessment of the evidence, MacDonald offers an alternative reconstruction of Q and an alternative solution to the Synoptic Problem: the Q+/Papias Hypothesis. To do so, he reconstructs and interprets two lost books about Jesus: the earliest Gospel, which was used as a source by the authors of Mark, Matthew, and Luke; and the earliest commentary on the Gospels, by Papias of Hierapolis, who apparently knew Mark, Matthew, and the lost Gospel, which he considered to be an alternative Greek translation of a Semitic Matthew. MacDonald also explores how these two texts, well known into the fourth century, shipwrecked with the canonization of the New Testament and the embarrassment at outmoded eschatologies in both the lost Gospel and Papias’s Exposition.
Statistics is the activity of inferring results about a population given a sample. Historically, statistics books assume an underlying distribution to the data (typically, the normal distribution) and derive results under that assumption. Unfortunately, in real life, one cannot normally be sure of the underlying distribution. For that reason, this book presents a distribution-independent approach to statistics based on a simple computational counting idea called resampling. This book explains the basic concepts of resampling, then system atically presents the standard statistical measures along with programs (in the language Python) to calculate them using resampling, and finally illustrates the use of the measures and programs in a case study. The text uses junior high school algebra and many examples to explain the concepts. Th e ideal reader has mastered at least elementary mathematics, likes to think procedurally, and is comfortable with computers. Table of Contents: The Basic Idea / Pragmatic Considerations when Using Resampling / Terminology / The Essential Stats / Case Study: New Mexico's 2004 Presidential Ballots / References / Bias Corrected Confidence Intervals / Appendix B
In the current environment of deepening class and income inequality, it is essential to understand the socio-economic conditions that shape the health of individuals and communities. Now in its third edition, Dennis Raphael’s Social Determinants of Health offers a comprehensive discussion of the primary factors that influence the health of Canada’s population. This seminal text on the social determinants of health contains contributions from top academics and high-profile experts from across the country. Taking a public policy approach, the authors in this edited collection critically analyze the structural inequalities embedded in our society and the socio-economic factors that affect health, including income, education, employment, housing, food security, gender, and race. The thorough updates to this edition include a greater focus on the political mechanisms that explain the distribution of the social determinants of health and additional material on public policy, early childhood education in Canada, and the determinants of Indigenous peoples’ health. Rich in pedagogical tools including critical thinking questions and lists of recommended readings and online resources, this book will actively engage students and researchers alike.
Praise for the First Edition "...a reference for everyone who is interested in knowing and handling uncertainty." —Journal of Applied Statistics The critically acclaimed First Edition of Understanding Uncertainty provided a study of uncertainty addressed to scholars in all fields, showing that uncertainty could be measured by probability, and that probability obeyed three basic rules that enabled uncertainty to be handled sensibly in everyday life. These ideas were extended to embrace the scientific method and to show how decisions, containing an uncertain element, could be rationally made. Featuring new material, the Revised Edition remains the go-to guide for uncertainty and decision making, providing further applications at an accessible level including: A critical study of transitivity, a basic concept in probability A discussion of how the failure of the financial sector to use the proper approach to uncertainty may have contributed to the recent recession A consideration of betting, showing that a bookmaker's odds are not expressions of probability Applications of the book’s thesis to statistics A demonstration that some techniques currently popular in statistics, like significance tests, may be unsound, even seriously misleading, because they violate the rules of probability Understanding Uncertainty, Revised Edition is ideal for students studying probability or statistics and for anyone interested in one of the most fascinating and vibrant fields of study in contemporary science and mathematics.
A step-by-step guide to computing and graphics in regression analysis In this unique book, leading statisticians Dennis Cook and Sanford Weisberg expertly blend regression fundamentals and cutting-edge graphical techniques. They combine and up- date most of the material from their widely used earlier work, An Introduction to Regression Graphics, and Weisberg's Applied Linear Regression; incorporate the latest in statistical graphics, computing, and regression models; and wind up with a modern, fully integrated approach to one of the most important tools of data analysis. In 23 concise, easy-to-digest chapters, the authors present:? A wealth of simple 2D and 3D graphical techniques, helping visualize results through graphs * An improved version of the user-friendly Arc software, which lets readers promptly implement new ideas * Complete coverage of regression models, including logistic regression and generalized linear models * More than 300 figures, easily reproducible on the computer * Numerous examples and problems based on real data * A companion Web site featuring free software and advice, available at www.wiley.com/mathem atics Accessible, self-contained, and fully referenced, Applied Regression Including Computing and Graphics assumes only a first course in basic statistical methods and provides a bona fide user manual for the Arc software. It is an invaluable resource for anyone interested in learning how to analyze regression problems with confidence and depth.
An exploration of regression graphics through computer graphics. Recent developments in computer technology have stimulated new and exciting uses for graphics in statistical analyses. Regression Graphics, one of the first graduate-level textbooks on the subject, demonstrates how statisticians, both theoretical and applied, can use these exciting innovations. After developing a relatively new regression context that requires few scope-limiting conditions, Regression Graphics guides readers through the process of analyzing regressions graphically and assessing and selecting models. This innovative reference makes use of a wide range of graphical tools, including 2D and 3D scatterplots, 3D binary response plots, and scatterplot matrices. Supplemented by a companion ftp site, it features numerous data sets and applied examples that are used to elucidate the theory. Other important features of this book include: * Extensive coverage of a relatively new regression context based on dimension-reduction subspaces and sufficient summary plots * Graphical regression, an iterative visualization process for constructing sufficient regression views * Graphics for regressions with a binary response * Graphics for model assessment, including residual plots * Net-effects plots for assessing predictor contributions * Graphics for predictor and response transformations * Inverse regression methods * Access to a Web site of supplemental plots, data sets, and 3D color displays. An ideal text for students in graduate-level courses on statistical analysis, Regression Graphics is also an excellent reference for professional statisticians.
This volume brings together two hitherto disparate domains of scholarly inquiry: organization and management studies on the one hand, and the study of visual and multimodal communication on the other. Within organization and management studies it has been recognized that organizational reality and communication are becoming increasingly visual, and, more generally, multimodal, whether in digital form or otherwise. Within multimodality studies it has been noted that many forms of contemporary communication are deeply influenced by organizational and managerial communication, as formerly formal and bureaucratic types of communication increasingly adopt promotional language and multimodal document presentation. Visual and Multimodal Research in Organization and Management Studies integrates these two domains of research in a way that will benefit both. In particular, it conceptually and empirically connects recent insights from visual and multimodality studies to ongoing discussions in organization and management theory. Throughout, the book shows how a visual/multimodal lens enriches and extends what we already know about organization, organizations, and practices of organizing, but also how concepts from organization and management studies can be highly productive in further developing insights on visual and multimodal communication. Due to its essentially interdisciplinary objectives, the book will prove inspiring for academics and scholars of management, the sociology of organizations as well as related disciplines such as applied linguistics and visual studies.
This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.
Publisher's Note: There is a new edition of Harrison's Principles of Internal Medicine. The 21st edition contains the most timely and comprehensive updates from the world's top experts. MASTER MODERN MEDICINE! Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible. Essential for practice and education, the landmark 20th Edition features: Thoroughly revised content—covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison’s. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care. State-of-the-art coverage of disease mechanisms: Harrison’s focuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention. Harrison’s summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system’s role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals. All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals. New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine—Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine. Important and timely new chapters—such as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and more—offer the very latest, definitive perspectives on must-know topics in medical education and practice. Updated clinical guidelines, expert opinions, and treatment approaches from world-renowned editors and authors contribute to the accuracy and immediacy of the text material and pres
WHEN YOUR LIFE IS LIKE A CIRCUS"....and whose life isn't? Here's the story of a family of entertainers with 48 years of real life experiences of international entertainment in circuses and stage productions that included hanging from a helicopter while strapped in a straightjacket! Brushes with death from rogue elephants, traveling hundreds of "mountain miles" a day, and meeting strangers who turned out to be 'angels' who showed up at "just the right time" are all integral parts of this exciting testimony of a family who felt God was directing their paths and who learned how to listen to His directions as they enjoyed His blessings along the way. This book contains the story of an entire family who took their God given talents and developed programs to motivate "children of all ages" to be the very best they were created to be! It's a true life story that can inspire the reader with the motivation to get thru challenges as THEY listen to God's direction in THEIR personal lives encouraging everyone to "MAKE CHRIST THEIR RINGMASTER"!
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