This is a new edition of the first comprehensive text to show how the advances in molecular and cellular biology and in the basic neurosciences have brought the revolution in molecular medicine to the field of psychiatry. The book begins with a review of basic neuroscience and methods for studying neurobiology in human patients then proceeds to discussions of all major psychiatric syndromes with respect to knowledge of their etiology, pathophysiology, and treatment. Emphasis is placed on synthesizing information across numerous levels of analysis, including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, and behavior, and in translating information from the basic laboratory to the clinical laboratory and finally to clinical treatment. Editors Dennis Charney and Eric Nestle, along with their six section editors and over 150 contributors, have revised and updated all 80 chapters from the previous edition and have added new chapters on topics relating to, for example, genetics, experimental therapeutics, and late-life mood disorders. Both a textbook and a reference book, Neurobiology of Mental Illness is intended for psychiatrists, neuroscientists, and upper level students.
Performance of Bio-based Building Materials provides guidance on the use of bio-based building materials (BBBM) with respect to their performance. The book focuses on BBBM currently present on the European market. The state-of-the-art is presented regarding material properties, recommended uses, performance expectancies, testing methodology, and related standards. Chapters cover both 'old and traditional' BBBM since quite a few of them are experiencing a comeback on the market. Promising developments that could become commercial in the near future are presented as well. The book will be a valuable reference resource for those working in the bio-based materials research community, architects and agencies dealing with sustainable construction, and graduate students in civil engineering. - Takes a unique approach to bio-based materials and presents a broad overview of the topics on relevant areas necessary for application and promotion in construction - Contains a general description, notable properties related to performance, and applications - Presents standards that are structured according to performance types
When Pueblo Indians say, “The first white man our people saw was a black man,” they are referring to Esteban, who came to New Mexico in 1539. After centuries of negative portrayals, this book highlights Esteban’s importance in America’s early history. Books about the history of the American West have ignored Esteban or belittled his importance, often using his slave nickname, Estebanico. What little we know about Esteban comes from Álvar Núñez Cabeza de Vaca and other Spanish chroniclers, whose condescension toward the African slave has carried over into most history books. In this work Herrick dispels the myths and outright lies about Esteban. His biography emphasizes Esteban rather than the Spaniards whose exploits are often exaggerated and jingoistic in the sixteenth-century chronicles. He gives Esteban full credit for his courage and his skill as a linguist and cultural intermediary who was trusted and respected by Indians from many tribes across the continent.
A new global focus, new editorial team, and new content make Principles and Practice of Gynecologic Oncology, 7th Edition an invaluable resource for practitioners, researchers, and students who need an authoritative reference for understanding and treating gynecologic cancers. This edition maintains the practical, multidisciplinary approach that encompasses surgery, medical oncology, radiation oncology, and pathology, reflecting the many recent advances in each area.
Acclaimed journalist Dennis Covington examines how faith and violence shape our world. In war zones witnessing widespread conflict, what makes life at all worth living? When chaos becomes a way of life in places where religion and violence intersect, what do people hold on to? If religious belief is, as Christopher Hitchens argues, the cause of wars and genocide, then is faith the cure? Dennis Covington pursued answers to these questions for years, traveling deep into places like Syria, Mexico, and the American South. Looking not for rigid doctrines, creeds, or beliefs -- which, he says, can be contradictory, even dangerous -- he sought something bigger and more fundamental: faith. It's faith in goodness, kindness, and the humanity of the smallest moments that makes the most difficult times bearable. The young bomb victim who offers a smile from his hospital bed, the grieving parent who shares a photograph, the joined hands of men who were previously mortal enemies, and Covington's own family turmoil. These are some of the moments that leave him touching the beating heart of what it truly is to live. Like Covington's widely celebrated Salvation on Sand Mountain, Revelation is an intensely personal journey that goes to the edges of a world filled with violence and religious strife to find the enduring worth of living.
The market for durable products using modified wood has increased substantially during the last few years. This is partly because of the restriction on the use of toxic preservatives due to environmental concerns, and to lower maintenance cost and time. Furthermore, as sustainability becomes a greater concern, the environmental impact of construction and interior materials is factored in planning by considering the whole life cycle and embodied energy of the materials used. Wood is modified to improve its intrinsic properties, enhance the range of applications of timber, and to acquire the form and functionality desired by engineers without calling the environmental friendliness into question. Wood modification processes are at various stages of development, and the challenges faced in scaling up to industrial applications differ. The aim of this book is to put together the key elements of the changes of wood constituents and the related changes in wood properties of modified wood. Further, a selection of the principal technologies implemented in wood modification are presented. This work is intended for researchers, professionals of timber construction, as well as students studying the science of materials, civil engineering and architecture. This work is not exhaustive, but intends to deliver an outline of the scientific disciplines necessary to apprehend the technologies of wood modification and its behavior during treatment, as well as during its use.
Based on the Diagnostic and Statistical Manual for Primary Care: Child and Adolescent Version (DSM-PC), this state-of-the-art reference expertly guides you through normal and abnormal development and behavior for all pediatric age groups. See how neurobiological, environmental, and human relationship factors all contribute to developmental and behavioral disorders and know how to best diagnose and treat each patient you see. Accurately identify developmental and behavioral problems using the Diagnostic and Statistical Manual for Primary Care criteria, and evidence-based guidelines. Gain a clear understanding of the "normal" boundaries and variations within specific disorders. Make informed therapeutic decisions with the integration of basic science and practical information and recommendations from the Society of Developmental and Behavioral Pediatrics and the American Academy of Pediatrics. Avoid legal and ethical implications by consulting the Law, Policy, and Ethics chapter.
The book that serves as the basis for the popular “Harrison’s Podclass” podcast series! This outstanding collection of internal medicine Q&A is perfect for prepping for board or shelf exams, getting in multiple “reps” of self directed learning, and increasing your understanding of clinical reasoning. It’s packed with 1,000+ high-quality clinical vignettes, with expert, on-point explanations for correct and incorrect answers. Harrison’s Principles of Internal Medicine Self-Assessment and Board Review reflects all the specialties of internal medicine, and has been exhaustively revised and updated to reflect hundreds of never-before published Q&A in board-style format. This great resource will bolster your understanding of pathophysiology, epidemiology, differential diagnosis, clinical decision making, and therapeutics. Illustrations, radiographs, and pathology slides are included throughout. Each question is accompanied by a complete answer and explanation, and cross-referenced to Harrison’s Principles of Internal Medicine for deeper-dive understanding. 325 full-color photos and illustrations Clinical vignettes and Q&A presented in board-style format Content consistent with board exam blueprint in internal medicine Aligned with Harrison’s Principles of Internal Medicine, the global authority in medicine Explanations for correct and incorrect answer choices
Market: medical students (18,000/ year); internists (75,000); internal medicine and family medicine residents (30,000), nurse practitioners (50,000), physician assistants (40,000), infectious diseases specialists (15,000); infectious diseases fellows (800) public health education and practice
The most widely read textbook in the history of medicine – made more essential to practice and education by an unmatched array of multi-media content Through six decades, no resource has matched the encyclopedic scope, esteemed scholarship, and scientific rigor of Harrison’s Principles of Internal Medicine, both as a textbook and as a clinical reference. It remains the most universally respected textbook in all of medical publishing and the pinnacle of current medical knowledge. The eighteenth edition of Harrison’s features expanded and more in-depth coverage of key issues in clinical medicine, pathophysiology, and medical education. The acclaimed Harrison’s DVD has been updated to include 53 chapters not found in the text; 14 all-new how-to videos commissioned specifically for Harrison’s; PowerPoint presentations on essential topics in medical education; and hundreds of bonus illustrations. Presented in two volumes NEW text design greatly enhances readability NEW chapters on cutting-edge topics in clinical medicine Expanded focus on global considerations of health and disease Editor-in-Chief: Dan Longo, MD (Boston, MA) is Professor of Medicine, Brigham and Women’s Hospital/Harvard Medical School.
Publisher's Note: There is a new edition of Harrison's Principles of Internal Medicine. The 21st edition contains the most timely and comprehensive updates from the world's top experts. MASTER MODERN MEDICINE! Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible. Essential for practice and education, the landmark 20th Edition features: Thoroughly revised content—covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison’s. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care. State-of-the-art coverage of disease mechanisms: Harrison’s focuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention. Harrison’s summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system’s role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals. All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals. New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine—Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine. Important and timely new chapters—such as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and more—offer the very latest, definitive perspectives on must-know topics in medical education and practice. Updated clinical guidelines, expert opinions, and treatment approaches from world-renowned editors and authors contribute to the accuracy and immediacy of the text material and pres
Introducing the most dramatically revised edition of Harrison's ever! Now with NEW bonus DVD with 37 chapters and more than 500 brand new images and video clips! MORE THAN TRUSTED, BEYOND ESSENTIAL . . . The #1 selling medical textbook worldwide, Harrison's has defined internal medicine for millions of clinicians and students. The new Seventeenth Edition retains Harrison's acclaimed balance of pathobiology, cardinal signs and manifestations of disease, and best approaches to patient management, yet has been massively updated to give you an innovative array of bold new features and content. If ever there was one must-have resource for clinicians and students - this is it! UNMATCHED EXPERTISE AT YOUR FINGERTIPS As an unprecedented amount of medical information bombards you and your patients, where do you go to sort it out and make sense of it all? When your patients request clarification on something they've “printed off” where do you turn for expert explanations? The same trusted resource physicians and students have turned to for over fifty years: Harrison's Principles of Internal Medicine. Now more than ever, trust Harrison's to filter and clarify the exploding knowledge base, to highlight the breakthroughs, and to deliver a clear, balanced distillation of the best and most current information on which to base clinical decisions. THE MOST EXCITING AND EXTENSIVELY REVISED EDITION EVER! Here are just a few of the reasons why the new 17th Edition of Harrison's is the best edition yet: Bonus companion DVD featuring: 37 new “e-chapters”; over 500 brand-new radiological, laboratory, and clinical images, including complete atlases; state-of-the-art video clips; an Image Bank of nearly all the illustrations contained in the parent text, and much more Expanded, modernized illustration program with more than 800 brand-new, additional illustrations-a 60% increase over the previous edition Dozens of brand new chapters on vital topics in medical education and clinical practice: Global Issues in Medicine: Patient Safety and Health Quality; Health Disparities: Atlas of EKGs; Clinical Management of Obesity: Atlas of Hematology: Atlases of Chest, Neurological, and Cardiovascular Radiology, and much more! Also included a complete new Section on biological foundations and emerging clinical applications of regenerative medicine! Brand new, reader-friendly text design optimizes the full-color format An expanded, innovative focus on global health NEW Global Advisory Board comprised of 11 prominent medical experts from Asia, India, Europe, and South America Revision of the popular On Line Learning Center, which offers more skill-sharpening self-assessment questions and answers, plus additional case studies for helping you apply Harrison's content to the daily care of patients Harrison's related products are available in a full suite of formats to meet all your educational and clinical needs. Harrison's Practice of Medicine is a complete database of more than 700 clinical topics formatted for use at the point of care. The Harrison's Manual of Medicine is one of the most popular and heavily used handbook-sized resources in internal medicine. The Harrison's Self-Assessment and Board Review features more than 1000 board-type cases and questions and highlights the use of Harrison's as a great board prep resouce.
Infectious Diseases – as only Harrison’s can cover them A Doody's Core Title for 2017! Featuring a superb compilation of chapters related to infectious diseases derived from Harrison’s Principles of Internal Medicine, Nineteenth Edition (including content from the acclaimed Harrison’s DVD, now available here in print), this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find 137 chapters from more than 190 renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. Features: • Current, complete coverage of need-to-know topics, including infections in organ systems, bacterial infections, viral infections, prion diseases, fungal infections, and protozoal infections • Addresses underlying epidemiologic, pathophysiologic, and genetic factors • Integration of pathophysiology with clinical management • Includes special update on Zika virus etiology, clinical manifestations, and complications • The chapter on HIV infections and AIDS by Anthony Fauci and Dr. H. Clifford Lane is widely considered to be a classic in the field • Two chapters comprise atlases of images that will prove invaluable in clinical assessments • High-yield board review questions make this text ideal for keeping current and preparing for the boards • Helpful appendix of laboratory values of clinical importance
Infectious Diseases – as only Harrison’s can cover it Featuring a superb compilation of chapters related to infectious diseases that appear in Harrison’s Principles of Internal Medicine, Eighteenth Edition, this concise, full-color clinical companion delivers the latest knowledge in the field backed by the scientific rigor and authority that have defined Harrison’s. You will find content from renowned editors and contributors in a carry-anywhere presentation that is ideal for the classroom, clinic, ward, or exam/certification preparation. Features Current, complete coverage of need-to-know topics, including infections in organ systems, bacterial infections, viral infections, prion diseases, fungal infections, and protozoal infections Addresses underlying epidemiologic, pathophysiologic, and genetic factors Important material on HIV infections and AIDS by Anthony S. Fauci and H. Clifford Lane Two image-based chapters comprise atlases valuable to clinical assessment: rashes associated with fever and blood smears of the various stages of the parasites causing malaria and babesiosis Integration of pathophysiology with clinical management 121 high-yield questions and answers drawn from Harrison’s Principles of Internal Medicine Self-Assessment and Board Review, 18e Content updates and new developments since the publication of Harrison’s Principles of Internal Medicine, 18e 132 chapters written by physicians who are recognized experts in the field of infectious diseases Helpful appendix of laboratory values of clinical importance
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