Sources and Methods of Historical Demography covers the fundamental sources, methods, and approaches to explanatory modeling for describing, analyzing, and understanding demographic features of past societies. The book discusses the intellectual ancestry of historical demographic research, beginning in the 17th century; as well as the logic of basic techniques for reconstructing and analyzing information from fundamental source materials. The text also describes the full range of disciplines that have made major contributions to historical demography, and examples of empirical research. The book concludes by arguing the case for conducting historical demographic research with a broad, interdisciplinary ideal in mind. Historians and sociologists will find the book invaluable.
Collective Action and the Civil Rights Movement is a theoretical study of the dynamics of public-spirited collective action as well as a substantial study of the American civil rights movement and the local and national politics that surrounded it. In this major historical application of rational choice theory to a social movement, Dennis Chong reexamines the problem of organizing collective action by focusing on the social, psychological, and moral incentives of political activism that are often neglected by rational choice theorists. Using game theoretic concepts as well as dynamic models, he explores how rational individuals decide to participate in social movements and how these individual decisions translate into collective outcomes. In addition to applying formal modeling to the puzzling and important social phenomenon of collective action, he offers persuasive insights into the political and psychological dynamics that provoke and sustain public activism. This remarkably accessible study demonstrates how the civil rights movement succeeded against difficult odds by mobilizing community resources, resisting powerful opposition, and winning concessions from the government.
In almost every town in America there are places where strange things happen. The perfect companion to The International Directory of Haunted Places, this revised and updated edition of Haunted Places is both a fascinating and unusual travel guide as well as an indispensable casebook for those interested in the paranormal. From buildings and parks believed to have resident ghosts and poltergeists to areas where Bigfoot or UFO sightings are most frequently reported, Haunted Places will lead you to more than 2,000 sites of paranormal activity across the United States. Organized alphabetically by state, each entry is referenced to an extensive bibliography of sources-with descriptions, addresses, phone numbers, Web sites, and travel directions provided for all locations.
A remnant of the Renaissance : the transnational iconography of justice -- Civic space, the public square, and good governance -- Obedience : the judge as the loyal servant of the state -- Of eyes and ostriches -- Why eyes? : color, blindness, and impartiality -- Representations and abstractions : identity, politics, and rights -- From seventeenth-century town halls to twentieth-century courts -- A building and litigation boom in Twentieth-Century federal courts -- Late Twentieth-Century United States courts : monumentality, security, and eclectic imagery -- Monuments to the present and museums of the past : national courts (and prisons) -- Constructing regional rights -- Multi-jurisdictional premises : from peace to crimes -- From "rites" to "rights" -- Courts : in and out of sight, site, and cite -- An iconography for democratic adjudication.
The jury trial is one of the formative elements of American government, vitally important even when Americans were still colonial subjects of Great Britain. When the founding generation enshrined the jury in the Constitution and Bill of Rights, they were not inventing something new, but protecting something old: one of the traditional and essential rights of all free men. Judgment by an “impartial jury” would henceforth put citizen panels at the very heart of the American legal order. And yet at the dawn of the 21st century, juries resolve just two percent of the nation’s legal cases and critics warn that the jury is “vanishing” from both the criminal and civil courts. The jury’s critics point to sensational jury trials like those in the O. J. Simpson and Menendez cases, and conclude that the disappearance of the jury is no great loss. The jury’s defenders, from journeyman trial lawyers to members of the Supreme Court, take a different view, warning that the disappearance of the jury trial would be a profound loss. In The Jury in America, a work that deftly combines legal history, political analysis, and storytelling, Dennis Hale takes us to the very heart of this debate to show us what the American jury system was, what it has become, and what the changes in the jury system tell us about our common political and civic life. Because the jury is so old, continuously present in the life of the American republic, it can act as a mirror, reflecting the changes going on around it. And yet because the jury is embedded in the Constitution, it has held on to its original shape more stubbornly than almost any other element in the American regime. Looking back to juries at the time of America's founding, and forward to the fraught and diminished juries of our day, Hale traces a transformation in our understanding of ideas about sedition, race relations, negligence, expertise, the responsibilities of citizenship, and what it means to be a citizen who is “good and true” and therefore suited to the difficult tasks of judgment. Criminal and civil trials and the jury decisions that result from them involve the most fundamental questions of right, and so go to the core of what makes the nation what it is. In this light, in conclusion, Hale considers four controversial modern trials for what they can tell us about what a jury is, and about the fate of republican government in America today.
Nationalism and Desire in Early Historical Fiction analyses a sequence of early-nineteenth-century British and American texts from a perspective informed by Rene Girard's theory of triangular of 'mimetic' desire. Jane Porter's The Scottish Chiefs , Sydney Owenson's The Wild Irish Girl , Sir Walter Scott's Waverley , Old Mortality , Rob Roy , The Pirate and Redgauntlet , and Fenimore Cooper's The Last of the Mohicans and Lionel Lincoln are given detailed new readings. General conclusions about the relationship of desire and nationalism in historical fiction are proposed.
The Epic Struggle of Freedom and Justice Against the Tyrannies of the 17th Century Continues, as European Cunning Meets American Courage! The Thirty Years War continues to ravage 17th century Europe, but a new force is gathering power and influence: the Confederated Principalities of Europe, an alliance between Gustavus Adolphus, King of Sweden, and the West Virginians from the 20th century led by Mike Stearns who were hurled centuries into the past by a mysterious cosmic accident. The democratic ideals of the CPE have aroused the implacable hostility of Cardinal Richelieu, effective ruler of France, who has moved behind the scenes, making common cause with old enemies to stop this new threat to the privileged and powerful. But the CPE is also working in secret. A group of West Virginians have secretly traveled to Venice where their advanced medical knowledge may prevent the recurrence of the terrible plague which recently killed a third of the city-state's population. At the same time, the group hopes to establish commercial ties with Turkey's Ottoman Empire, then at the height of its power. And, most important, they hope to establish private diplomatic ties with the Vatican, exploiting Pope Urban VIII's misgivings about the actions of Richelieu and the Hapsburgs. But a Venetian artisan involved with the West Virginians may cause all their plans to come to naught. Having read 20th century history books of the period, he has become determined to rescue Galileo from his trial for heresy. The Americans are divided on whether to help him or stop him¾and whether he succeeds or fails, the results may be catastrophic for the CPE. At the publisher's request, this title is sold without DRM (Digital Rights Management). "A rich complex alternate history with great characters and vivid action. A great read and an excellent book." ¾David Drake "Gripping . . . depicted with power!" ¾Publishers Weekly ". . . formidable historiography, wit, balance (there are few stupid bad guys¾well, England's Charles I), intelligently ferocious women, and mouth-watering displays of alternate technology . . . [many readers] will turn every page and cry for more!" ¾Booklist "[Flint takes] historic speculation to a new level in a tale that combines accurate historical research with bold leaps of the imagination. Fans of alternate history and military sf should enjoy this rousing tale of adventure and intrigue." ¾Library Journal
A new global focus, new editorial team, and new content make Principles and Practice of Gynecologic Oncology, 7th Edition an invaluable resource for practitioners, researchers, and students who need an authoritative reference for understanding and treating gynecologic cancers. This edition maintains the practical, multidisciplinary approach that encompasses surgery, medical oncology, radiation oncology, and pathology, reflecting the many recent advances in each area.
“A compelling narrative that moves crisply through the murder, the lynching, and the cover-up by silence that local residents thereafter affected.”—The Journal of American History On a warm August night in 1911, Zachariah Walker was lynched—burned alive—by an angry mob on the outskirts of Coatesville, a prosperous Pennsylvania steel town. At the time of his very public murder, Walker, an African American millworker, was under arrest for the shooting and killing of a respected local police officer. Investigated by the NAACP, the horrific incident garnered national and international attention. Despite this scrutiny, a conspiracy of silence shrouded the events, and the accused men and boys were found not guilty at trial. More than 100 years after the lynching, authors Dennis B. Downey and Raymond M. Hyser bring new insight to events that rocked a community.
Tuning your database for optimal performance means more than following a few short steps in a vendor-specific guide. For maximum improvement, you need a broad and deep knowledge of basic tuning principles, the ability to gather data in a systematic way, and the skill to make your system run faster. This is an art as well as a science, and Database Tuning: Principles, Experiments, and Troubleshooting Techniques will help you develop portable skills that will allow you to tune a wide variety of database systems on a multitude of hardware and operating systems. Further, these skills, combined with the scripts provided for validating results, are exactly what you need to evaluate competing database products and to choose the right one. - Forward by Jim Gray, with invited chapters by Joe Celko and Alberto Lerner - Includes industrial contributions by Bill McKenna (RedBrick/Informix), Hany Saleeb (Oracle), Tim Shetler (TimesTen), Judy Smith (Deutsche Bank), and Ron Yorita (IBM) - Covers the entire system environment: hardware, operating system, transactions, indexes, queries, table design, and application analysis - Contains experiments (scripts available on the author's site) to help you verify a system's effectiveness in your own environment - Presents special topics, including data warehousing, Web support, main memory databases, specialized databases, and financial time series - Describes performance-monitoring techniques that will help you recognize and troubleshoot problems
These contextual cases remind us that we think best when the issues before us evoke both passion and professionalism. Here are vividly detailed everyday tensions of librarianship, portrayed among human complexities and imaginable lives. We become stronger not by crafting elegant solutions, but by conducting focused contemplation and multifaceted talk.' -Dr David Carr, Associate Professor, School of Information and Library Science, University of North Carolina at Chapel Hill
On Highway 61 explores the historical context of the significant social dissent that was central to the cultural genesis of the sixties. The book is going to search for the deeper roots of American cultural and musical evolution for the past 150 years by studying what the Western European culture learned from African American culture in a historical progression that reaches from the minstrel era to Bob Dylan. The book begins with America's first great social critic, Henry David Thoreau, and his fundamental source of social philosophy:–––his profound commitment to freedom, to abolitionism and to African–American culture. Continuing with Mark Twain, through whom we can observe the rise of minstrelsy, which he embraced, and his subversive satirical masterpiece Huckleberry Finn. While familiar, the book places them into a newly articulated historical reference that shines new light and reveals a progression that is much greater than the sum of its individual parts. As the first post–Civil War generation of black Americans came of age, they introduced into the national culture a trio of musical forms—ragtime, blues, and jazz— that would, with their derivations, dominate popular music to this day. Ragtime introduced syncopation and become the cutting edge of the modern 20th century with popular dances. The blues would combine with syncopation and improvisation and create jazz. Maturing at the hands of Louis Armstrong, it would soon attract a cluster of young white musicians who came to be known as the Austin High Gang, who fell in love with black music and were inspired to play it themselves. In the process, they developed a liberating respect for the diversity of their city and country, which they did not see as exotic, but rather as art. It was not long before these young white rebels were the masters of American pop music – big band Swing. As Bop succeeded Swing, and Rhythm and Blues followed, each had white followers like the Beat writers and the first young rock and rollers. Even popular white genres like the country music of Jimmy Rodgers and the Carter Family reflected significant black influence. In fact, the theoretical separation of American music by race is not accurate. This biracial fusion achieved an apotheosis in the early work of Bob Dylan, born and raised at the northern end of the same Mississippi River and Highway 61 that had been the birthplace of much of the black music he would study. As the book reveals, the connection that began with Thoreau and continued for over 100 years was a cultural evolution where, at first individuals, and then larger portions of society, absorbed the culture of those at the absolute bottom of the power structure, the slaves and their descendants, and realized that they themselves were not free.
We, the Jury is the dramatic story of seven jurors, who convicted Scott Peterson of murdering his wife, Laci, and their unborn son, Conner, despite a series of internal battles that brought the first major murder trial of the 21st century to the brink of a mistrial. The Peterson jurors argued and disagreed but eventually bonded to seal the fate of the icy killer who dumped his victims into the bullet-gray waters of San Francisco Bay. The seven jurors of We, the Jury were seven average Americans who never imagined the horrors they would face or the phantoms that would haunt them after they convicted the enigmatic murderer and recommended that he be put to death. This is the story of how the American jury system worked after being battered by critics for the way it functioned in the trials of O.J. Simpson and Michael Jackson. Unlike the jurors in those trials, who second-guessed themselves, the Peterson jurors do not question their decisions. It wasn’t one thing that condemned Scott Peterson, it was everything.
These two volumes of The New Testament and Greek Literature are the magnum opus of biblical scholar Dennis R. MacDonald, outlining the profound connections between the New Testament and classical Greek poetry. MacDonald argues that the Gospel writers borrowed from established literary sources to create stories about Jesus that readers of the day would find convincing. In Luke and Vergil MacDonald proposes that the author of Luke-Acts followed Mark’s lead in imitating Homer’s Iliad and Odyssey, but greatly expanded his project, especially in the Acts, but adding imitations not only of the epics but also of Euripides’ Bacchae and Plato’s Socratic dialogues. The potential imitations include spectacular miracles, official resistance, epiphanies, prison breaks, and more. The book applies mimesis criticism and uses side-by-side comparisons to show how early Christian authors portrayed the origins of Christianity as more compelling than the Augustan Golden Age.
Part of James Atlas's Icons series, a revealing look at the life and work of David Lynch, one of the most enigmatic and influential filmmakers of our time
The apostle Paul--antifeminist conformist, or social radical? Combining New Testament studies with folkloristic methods to search for the true identity of Paul, the author sheds new light on the apocryphal Acts of Paul and the Pastoral Epistles of the canonical New Testament. With this book, the legends surrounding the apostle have been rescued from near oblivion and properly placed in the Pauline tradition. Formulated in the days of early Christianity and handed down through the centuries, they cast new light on Paul's views about the ordination of women, the forms of Christian community, and the meaning of the gospel for politics, society, and sexuality.
Written in a lively, accessible style and detailing the events of the Progressive Era and World War I (1901-1920), this book is the only interdisciplinary history covering this period currently available. 60+ illustrations.
Here is a book that was neither written by a human nor dictated by the Holy Spirit to a human. It is the perspective of an angel, a disinterested third party who is neither human nor divine. Augie is a working angel who, like most angels, troubleshoots and serves God as a messenger, guardian, avenger, chaperone—you name it, Augie has done it. For reasons unknown, Augie’s superiors select him to write a book, giving him no reason and no guidelines. Augie figures it must be to help humans understand the spirit world a little better. It was strange that Augie was selected because he takes a rather dim view of the human species. He feels that the sacrifice of Jesus to purchase mankind was like a human who spent a fortune to buy the Brooklyn Bridge. Being a good angel, however, he takes to his task willingly and digs into his case files—reports that all angels must submit following encounters with humans. He includes an after-action summary as a sort of debrief in which he records the important details that he feels humans are too ignorant to see on their own. The result is this book. Since heaven submitted it for publication, I guess they think Augie did an okay job.
From the 1970s through the mid-1980s, the Chicago Outfit dominated organized crime in Las Vegas. To ensure the smooth flow of cash, the gangsters installed a front man with no criminal background, Allen R. Glick, as the casino owner of record, Frank “Lefty” Rosenthal as the real boss of casino operations, and Tony Spilotro as the ultimate enforcer, who’d do whatever it took to protect their interests. It wasn’t long before Spilotro, also in charge of Vegas street crime, was known as the “King of the Strip.” Federal and local law enforcement, recognizing the need to rid the casinos of the mob and shut down Spilotro’s rackets, declared war on organized crime. The Battle for Las Vegas relates the story of the fight between the tough guys on both sides, told in large part by the agents and detectives who knew they had to win.
Percy's continental travels in the 1580s may be related to the early travels of Donne and to the plans of Catholic exiles for an invasion of England six years before the defeat of the Armada.
Family, Political Economy, and Demographic Change represents an unprecedented interdisciplinary effort to discover how changes in family life and demographic behavior actually occurred in this crucial period, and how people's lives were affected. The book takes issue with a number of the most influential demographic and sociological theories dealing with the evolution of the Western family and the factors responsible for fertility decline. As in so many other parts of Europe, the northern Italian community of Casalecchio experienced massive social and economic changes in the nineteenth and early twentieth centuries. Characterized by sharecropping agriculture and large, complex family households, the community faced the effects of industrialization, urbanization, and dramatic political change. Making use of unusually rich archival sources to reconstruct the live of 19,000 people who lived in Casalecchio during this period, Kertzer and Hogan challenge many current generalizations regarding the emergence of modern European society.
A tale of time travel and spiritual adventure, where a father travels back in time to save his son's life. He soon discovers that to save his son's life is murder.
The stereotype of the African American male as a criminal element in society continues to be a major obstacle to greater racial harmony and the elimination of discrimination and racism on all levels in the United States. Often, this criminal stereotype is internalized by African American youth, so they are made to feel as though delinquent behavior is expected from them, and many fall into this trap. Black Demons examines this stereotype and contends that much of the blame for its perpetuation comes from U.S. mass media's negative depictions of African American males. Rome argues that these images foster the myths that help to deepen and strengthen the stereotypes that have plagued the African American community since colonial times. By examining the origins of this criminal stereotype, how it has been used historically, and how it is presently employed, Rome reveals a dangerous current in media depictions of African Americans, one that threatens that community and taints U.S. society as it tries to overcome the legacy of racism. The African American male criminal stereotype continues to be used to justify covert and overt racism in contemporary U.S. society. From television to cinema, music to news coverage, mass media continue to depict African American males running from the law, committing crimes, victimizing women, and generally engaging in illegal behavior. Here, Rome examines those images and offers an explanation for this phenomenon. He discusses the impact of these images on both the African American community and on U.S. society in general. He considers the notion that there is a black pathology, a fundamental weakness in African American families that can be traced back to their experiences as slaves. Finally, he concludes that both the news media and entertainment outlets must discontinue their practice of equating young African American males with aggressiveness, lawlessness, and violence if racism is every to be truly abolished in the United States.
The fifth edition of The Corporate Counsellor's Deskbook offers insightful analysis of the key areas of the law of critical interest to in-house counsel and corporate law departments, as well as outside firms and attorneys who represent corporate clients on a regular basis.The authors provide step-by-step guidance on issues such as: Employment agreements and executive compensationManaging complex litigation and litigation budgetingImplementing internal procedures to protect against insider trading and internal file controlsTaking advantage of alternative dispute resolution formatsCounseling on employment law and intellectual propertyNoncompetition agreementsImport regulation and customs complianceEnvironmental law concerns.Additional topics in the Fifth Edition include:
Like many good stories of the old West, this one begins in a saloon. In 1914 in El Paso, Texas, two strangers strike up a conversation at the bar—Bill Roberts, a real-life figure who died in Hico, Texas, in 1950, and a former US Army scout whose brother knew Roberts by another name: Billy the Kid. So begins The Gospel According to Billy the Kid, a tale of the old New Mexico territory, corrupt lawmen, honest ranchers, murder, betrayal, and the explosive events of the Lincoln County War that sent young Billy off seeking justice—and headed toward a bloody rendezvous with a sheriff hired to track him down. In the saloon Roberts has us imagine another story, told thirty-three years later over shots of whiskey, about a young outlaw given a second chance to find himself, to find peace, and to finally grow up and out from under the shadow of his own infamy.
Publisher's Note: There is a new edition of Harrison's Principles of Internal Medicine. The 21st edition contains the most timely and comprehensive updates from the world's top experts. MASTER MODERN MEDICINE! Introducing the Landmark Twentieth Edition of the Global Icon of Internal Medicine The definitive guide to internal medicine is more essential than ever with the latest in disease mechanisms, updated clinical trial results and recommended guidelines, state-of-the art radiographic images, therapeutic approaches and specific treatments, hundreds of demonstrative full-color drawings, and practical clinical decision trees and algorithms Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine gives you the informational foundation you need to provide the best patient care possible. Essential for practice and education, the landmark 20th Edition features: Thoroughly revised content—covering the many new breakthroughs and advances in clinical medicine that have occurred since the last edition of Harrison’s. Chapters on acute and chronic hepatitis, management of diabetes, immune-based therapies in cancer, multiple sclerosis, cardiovascular disease, HIV, and many more, deliver the very latest information on disease mechanisms, diagnostic options, and the specific treatment guidance you need to provide optimal patient care. State-of-the-art coverage of disease mechanisms: Harrison’s focuses on pathophysiology with rigor, and with the goal of linking disease mechanisms to treatments. Improved understanding of how diseases develop and progress not only promotes better decision-making and higher value care, but also makes for fascinating reading and improved retention. Harrison’s summarizes important new basic science developments, such as the role of mitochondria in programmed and necrotic cell death, the immune system’s role in cancer development and treatment, the impact of telomere shortening in the aging and disease processes, and the role of the microbiome in health and disease. Understanding the role of inflammation in cardiovascular disease, the precise mechanisms of immune deficiency in HIV/AIDS, prions and misfolded proteins in neurodegenerative diseases, and obesity as a predisposition to diabetes are just a few examples of how this edition provides essential pathophysiology information for health professionals. All-new sections covering a wide range of new and emerging areas of vital interest to all healthcare professionals. New sections include: Sex and Gender-based Issues in Medicine; Obesity, Diabetes Mellitus, and Metabolic Syndrome; and Consultative Medicine—Plus, a new Part covering cutting-edge topics in research and clinical medicine includes great new chapters on the role of Epigenetics in Health and Disease, Behavioral Strategies to Improve Health, Genomics and Infectious Diseases, Emerging Neuro-Therapeutic Technologies, and Telomere Function in Health and Disease, and Network System Medicine. Important and timely new chapters—such as Promoting Good Health, LGBT Health, Systems of Healthcare, Approach to Medical Consultation, Pharmacogenomics, Antimicrobial Resistance, Worldwide Changes in Patterns of Infectious Diseases, Neuromyelitis Optica, and more—offer the very latest, definitive perspectives on must-know topics in medical education and practice. Updated clinical guidelines, expert opinions, and treatment approaches from world-renowned editors and authors contribute to the accuracy and immediacy of the text material and pres
In A Brotherhood of Liberty, Dennis Patrick Halpin shifts the focus of the black freedom struggle from the Deep South to argue that Baltimore is key to understanding the trajectory of civil rights in the late nineteenth and early twentieth centuries. In the 1870s and early 1880s, a dynamic group of black political leaders migrated to Baltimore from rural Virginia and Maryland. These activists, mostly former slaves who subsequently trained in the ministry, pushed Baltimore to fulfill Reconstruction's promise of racial equality. In doing so, they were part of a larger effort among African Americans to create new forms of black politics by founding churches, starting businesses, establishing community centers, and creating newspapers. Black Baltimoreans successfully challenged Jim Crow regulations on public transit, in the courts, in the voting booth, and on the streets of residential neighborhoods. They formed some of the nation's earliest civil rights organizations, including the United Mutual Brotherhood of Liberty, to define their own freedom in the period after the Civil War. Halpin shows how black Baltimoreans' successes prompted segregationists to reformulate their tactics. He examines how segregationists countered activists' victories by using Progressive Era concerns over urban order and corruption to criminalize and disenfranchise African Americans. Indeed, he argues the Progressive Era was crucial in establishing the racialized carceral state of the twentieth-century United States. Tracing the civil rights victories scored by black Baltimoreans that inspired activists throughout the nation and subsequent generations, A Brotherhood of Liberty highlights the strategies that can continue to be useful today, as well as the challenges that may be faced.
Tragedy at Graignes tells the story of Captain Bud Sophian, the only US Army officer who did not flee Graignes, France, as the Waffen SS overran the American positions and stormed the village. Sophian was a surgeon, and he refused to abandon the fourteen wounded paratroopers in his care. He surrendered by waving a white flag at the door of the badly shelled Norman church where his aid station was located. He hoped for fair prisoner treatment in accordance with the Geneva Convention of 1929. The German troops instead committed unspeakable atrocities, leaving many of the American prisoners mutilated in grotesque heaps. All of the American prisoners, including Sophian, were killed. Captain Sophians judgment and actions in the US Army were the culmination of the rich and challenging life he led prior to the Second World War. Buds correspondence with his sister and other Sophian archival materials tell the story of this compelling life. These letters are reproduced verbatim in Tragedy at Graignes: The Bud Sophian Story so that Bud and other authors may speak directly to you and to the historical record.
The Voice of Clinical ReasonHarrison’s Principles of Internal Medicine is the world's most trusted clinical medicine text—and a superb resource for learning the art and science of clinical reasoning. Recognized by healthcare professionals worldwide as the leading authority on applied pathophysiology and clinical medicine, Harrison’s Principles of Internal Medicine provides the informational foundation you need for the best patient care possible. This new edition is fully updated with timely new chapters and essential updates across the spectrum of internal medicine. Harrison's Principles of Internal Medicine stands as the benchmark for authoritative, practical information on patient care and the pathogenesis and clinical management of symptoms and signs and specific diseases. Written and edited by the world’s top experts in their respective fields, this landmark guide provides the comprehensive, accurate, and essential coverage of the pathogenesis, diagnosis, and treatment of disease. Harrison’s is world-renowned as the most authoritative source for: • Descriptions of disease mechanisms and how the clinician can apply that knowledge for the best patient care and optimal diagnosis and treatment of specific diseases • Clear, concise schemas that facilitate the generation of differential diagnoses to reason efficiently through complex real world clinical cases • The physiologic and epidemiologic basis of signs and symptoms, which are covered through a wealth of unsurpassed expert guidance and linked to the disease-specific chapters that follow • Updated clinical trial results and recommended guidelines • Excellent and extensive visual support, including radiographs, clinical photos, schematics, and high-quality drawings • Coverage of both therapeutic approaches and specific treatment regimens • Practical clinical decision trees and algorithms • Organ-specific sections, with clinically relevant pathophysiology and practical clinical advice on the approach to the patient, strategies towards building a differential diagnosis, outstanding clinical algorithms and diagnostic schema, a wealth of clinical images and diagrams, current clinical guidelines, general and specific approaches to therapy Harrison’s remains the most trusted resource in a world influenced by endless sources of medical information. The most timely and comprehensive updates from the world’s top experts are featured in the 21st edition: • Current coverage of the diagnosis and treatment of diseases, from COVID to dementia to sepsis to multiple sclerosis to lung cancer • Updated content that reflects new approved therapeutics and new practice-changing guidelines and evidence summaries • More than 1000 clinical, pathological, and radiographic photographs, diagnostic and therapeutic decision trees, and clear schematics and diagrams describing pathophysiologic processes • More than a dozen atlases featuring curated collections of visual aspects of diagnosis and management • Complete, updated curation and synthesis of primary medical literature which incorporates current data from major studies and clinical trials • Clinical reasoning resources and helpful disease/presentation schemas • Clinically relevant coverage of disease mechanics and pathophysiology, and related therapeutic mechanisms
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