The remarkable story of how today's brain scanning techniques were developed, told by one of the field's pioneers It is now possible to witness human brain activity while we are talking, reading, or thinking, thanks to revolutionary neuroimaging techniques like magnetic resonance imaging (MRI). These groundbreaking advances have opened infinite fields of investigation—into such areas as musical perception, brain development in utero, and faulty brain connections leading to psychiatric disorders—and have raised unprecedented ethical issues. In Looking Inside the Brain, one of the leading pioneers of the field, Denis Le Bihan, offers an engaging account of the sophisticated interdisciplinary research in physics, neuroscience, and medicine that have led to the remarkable neuroimaging methods that give us a detailed look into the human brain. Introducing neurological anatomy and physiology, Le Bihan walks readers through the historical evolution of imaging technology—from the x-ray and CT scan to the PET scan and MRI—and he explains how neuroimaging uncovers afflictions like stroke or cancer and the workings of higher-order brain activities, such as language skills. Le Bihan also takes readers on a behind-the-scenes journey through NeuroSpin, his state-of-the-art neuroimaging laboratory, and goes over the cutting-edge scanning devices currently being developed. Considering what we see when we look at brain images, Le Bihan weighs what might be revealed about our thoughts and unconscious, and discusses how far this technology might go in the future. Beautifully illustrated in color, Looking Inside the Brain presents the trailblazing story of the scanning techniques that provide keys to previously unimagined knowledge of our brains and our selves.
The remarkable story of how today's brain scanning techniques were developed, told by one of the field's pioneers It is now possible to witness human brain activity while we are talking, reading, or thinking, thanks to revolutionary neuroimaging techniques like magnetic resonance imaging (MRI). These groundbreaking advances have opened infinite fields of investigation—into such areas as musical perception, brain development in utero, and faulty brain connections leading to psychiatric disorders—and have raised unprecedented ethical issues. In Looking Inside the Brain, one of the leading pioneers of the field, Denis Le Bihan, offers an engaging account of the sophisticated interdisciplinary research in physics, neuroscience, and medicine that have led to the remarkable neuroimaging methods that give us a detailed look into the human brain. Introducing neurological anatomy and physiology, Le Bihan walks readers through the historical evolution of imaging technology—from the x-ray and CT scan to the PET scan and MRI—and he explains how neuroimaging uncovers afflictions like stroke or cancer and the workings of higher-order brain activities, such as language skills. Le Bihan also takes readers on a behind-the-scenes journey through NeuroSpin, his state-of-the-art neuroimaging laboratory, and goes over the cutting-edge scanning devices currently being developed. Considering what we see when we look at brain images, Le Bihan weighs what might be revealed about our thoughts and unconscious, and discusses how far this technology might go in the future. Beautifully illustrated in color, Looking Inside the Brain presents the trailblazing story of the scanning techniques that provide keys to previously unimagined knowledge of our brains and our selves.
At the crossroads of physics and neuroscience, this unique book offers a new approach to brain function based on Einstein's work on relativity and the cosmological constant. "The book goes back and forth between what we know about these two universes, the cosmos and our brain, their energy and their matter, be it black, grey or white. It alternates between the fundamental questions of contemporary physics and cosmology, and our knowledge of the functioning of the brain based in particular on the revelations of neuroimaging." D. L. B. The revolutionary hypothesis of a relativistic brain space-time sheds new light on our perception of the world, on our consciousness, on our social interactions and on mental illness. A masterful, daring book that invites us to a journey in thought, from the confines of the universe to the depths of the brain. Author of the best-selling book Le Cerveau de cristal (2012), Denis Le Bihan, a physician and a physicist, is a member of the French Academy of Sciences and of the National Academy of Medicine. He founded and directed NeuroSpin, and has received numerous prestigious international awards for his work in neuroimaging. On the cover: the letter represents the cosmological constant, Einstein's error, while the two brains, with their clocks, can be seen as two mental states of the same person or as two people interacting, within the framework of a relativistic brain space-time.
All living creatures inscribe their activity in space. Human beings acquire knowledge of this space by traversing it, listening to verbal descriptions, and looking at maps, atlases, and digital media. We memorize routes, compare distances mentally, and retrieve our starting place after a long journey. Space and Spatial Cognition provides an up-to-date introduction to the elements of human navigation and the mental representation of our environment. This book explores the mental capacities which enable us to create shortcuts, imagine new pathways, and thus demonstrate our adaptation to the environment. Using a multidisciplinary approach which draws on psychology, neuroscience, geography, architecture and the visual arts, the author presents answers to a number of questions. Which mental capacities do people mobilize when confronted with space? Which brain functions do they implement? How do digital technologies extend these capacities? By presenting space at the crossroads of a number of disciplines, this volume reveals how each of them enhances our understanding of human behaviour in space. Space and Spatial Cognition provides a unique insight into all facets of spatial cognition, including spatial behaviour, language, and future technologies. It will be the ideal companion for all students and researchers in the field.
This new clinical resource brings you a state-of-the-art comprehensive review on every clinical condition encountered in pediatric nephrology in one concise, clinically focused text. International experts provide you with the latest on epidemiology, diagnosis, investigations, management, and prognosis for a full range of pediatric kidney disorders. A full-color, highly visual, meticulously crafted format, makes this material remarkably easy for you to access and apply. Comprehensive Pediatric Nephrology also serves as an ideal resource for board review study for the ABP subspecialty boards in pediatric nephrology. Just the right amount of "need-to-know" basic science coupled with practical clinical guidance for every disorder helps you make efficient, informed decisions. The book provides a much needed update on the genetic origins of pediatric kidney disorders. Chapters about glomerulonephritis, nephrotic syndrome, and tubular disorders provide an orientation in the pathophysiology, differential diagnosis, and treatment of these heterogeneous disease entities. Disease specific chapters include diagnostic work-up, laboratory evaluation, and management of disorders and complications, making this necessary information readily accessible. The prevention and management of pediatric chronic renal failure and its complications are comprehensively covered in many detailed chapters. Four chapters devoted to childhood hypertension offer you insights into an increasingly prevalent condition among pediatric patients so you can treat them more effectively. A chapter on the role of the interventional radiologist in pediatric nephrology keeps you apprised of the latest advances in a key area in the field. The function of complementary and alternative medicine in patients with renal disease is reviewed for the first time in a standard pediatric nephrology textbook. A consistent organization throughout and a full-color layout lets you find diagnostic guidance quickly.
Advanced Human Nutrition, Fifth Edition provides a comprehensive overview of the human body and details why nutrients are important from a biochemical, physiological, and molecular perspective. Written for the upper-level undergraduate or graduate level majors course, the text clearly outlines metabolism and the molecular functions of nutrients, through the use of an accessible writing style and numerous figures and illustrations. A variety of pedagogical elements within the text, such as "Here's Where You Have Been" and "Here's Where You Are Going" help clarify key points from the chapter and provide real world-examples to bring the content to life. Each new print copy includes Navigate Advantage Access that unlocks a comprehensive and interactive eBook, student practice activities and assessments, a full Student Study Guide, a full suite of instructor resources, and learning analytics reporting tools.
The ever-increasing interest in the spine and its pathology is not surprising. Acting as the main support of an erect posture unique in the animal kingdom, the human spine is, owing to its numerous articulations, at the same time a supple structure that can respond to the many stresses which are put on it. Constant movement is necessary to preserve its function, but regular and well is also essential. The high frequency of spinal disorders result positioned rest ing from misuse is easily explained by day-to-day reality. Among the disorders that result from misuse of the spine, herniated disk, leading to radicular compression, is one of the most frequent. New tech niques, less invasive and yielding more precise information, have been pro gressively developed for the diagnosis of this disease and at the same time new methods of treatment have appeared, giving us a much broader range of choices and decisions to make. In the face of this evolving, complex situation, a multidisciplinary team from Strasbourg decided to clarify the topic. A single man's experience, what ever his qualities, would certainly have been insufficient and the necessarily limited views of a single speciality would also have been a handicap. This re markable work is thus the result of collaboration between clinical and inter ventional radiologists and a neurosurgeon.
What are the processes, from conception to adulthood, that enable a single cell to grow into a sentient adult? This work sets out a whole new framework for considering the complex topic of development, integrating data from cognitive studies, computational work, and neuroimaging.
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