Caught by the Police is the story of a talented, public-spirited and erudite man, with a multidimensional personality, a republican bent of mind, Indian values and English sensibilities. After a brilliant academic career, he joined the Royal Air Force in 1934 at the age of 19; unfortunately, he was forced to leave on contrived medical grounds. He got into the Indian Police due to a providential combination of circumstances and events, somewhat against his inclination. But once in it, he gave his all to his profession. A brave and intrepid police officer, he went on to become a celebrated police historian. He also wrote spiritual poetry, which forms a part of the book and, interestingly, could recite Shakespeare, Ghalib and the Bhagvad Gita with equal facility. Spanning a century of changing times, this book provides a unique account of the last decades of British Rule and the emergence of a new India, woven into the story of an extraordinary life lived in ordinary places, and a compelling family chronicle.
Enter the psyche of a serial killer, a desperate man trapped in a treacherous maze of murder, lies, love, and suspense. The violent love story Justified Murder defines destiny – accepting that which is written – versus fighting for control of one’s life. It is the classic battle between good and evil, only the thin line separating them is not so distinct. This thriller introduces David Hawthorne, a killer who must choose between true love and embracing the dark desires buried in his soul. Raised by a zealot Catholic preacher, David is betrayed by a treacherous woman. After his release from a mental hospital for her killing, a chance encounter leads to murder. Once the flood gates are open, David is compelled to kill again. David uses his dynamic personality as a TV reporter to manipulate viewers into feeling compassion for the killer, and his popularity soars. Unaware of his crimes, District Attorney Melanie Hunter begins a romantic relationship with David. Investigating the murder case is a well-respected detective, Harold Thompson. As the cat and mouse game between them begins, the detective learns that he and David have much in common. Meanwhile, David struggles to keep his three lives separate: his peaceful life with Melanie, his dark life as a serial killer, and his glamorous life as a TV reporter. Will David tame the monster within and live happily ever after with Melanie? Or will Harold bring the killer to justice?
Resurgent Asia analyses the phenomenal transformation of Asia, which would have been difficult to imagine, let alone predict, fifty years ago, when Gunnar Myrdal published Asian Drama. In doing so, it provides an analytical narrative of this remarkable story of economic development, situated in its wider context of historical, political, and social factors, and an economic analysis of the underlying factors, with a focus on critical issues in the process of, and outcomes in, development. In 1970, Asia was the poorest continent in the world, marginal except for its large population. By 2016, it accounted for three-tenths of world income, two-fifths of world manufacturing, and one-third of world trade, while its income per capita converged towards the world average. However, this transformation was associated with unequal outcomes across countries and between people. The analysis disaggregates Asia into its four constituent sub-regions--East, Southeast, South, and West--and further into fourteen economies--China, India, South Korea, Indonesia, Turkey, Taiwan, Thailand, Philippines, Malaysia, Singapore, Pakistan, Bangladesh, Vietnam, and Sri Lanka--which account for more than four-fifths of its population and income. This book enhances our understanding of development processes and outcomes in Asia over the past fifty years, draws out the analytical conclusions that contribute to contemporary debates on development, and highlights some lessons from the Asian experience for countries elsewhere. It is the first to examine the phenomenal changes that are transforming economies in Asia and shifting the balance of economic power in the world, while reflecting on the future prospects in Asia over the next twenty-five years. A rich, engaging, and fascinating read.
SECTION 1: Sepsis Diagnosis and Management 1. Precision Medicine in Septic Shock 2. Optimal Blood Pressure Target in Patients with Septic Shock 3. The Surviving Sepsis Campaign Guidelines in 2022: What is New and what has Changed? 4. Individualizing Hemodynamics in Septic Shock 5. Adjunctive Therapies in Sepsis: Current Status 6. Refractory Septic Shock: What are the Options 7. Steroids in Sepsis and Clinical Outcomes 8. Candida auris: Detection, Prevention, and Management 9. Empirical Antifungal Treatment: Is It Justified? 10. Role of Steroids in Severe Community acquired Pneumonia 11. Procalcitonin: Can It Differentiate Bacterial versus Fungal Infection SECTION 2: Antimicrobial Therapy in ICU 12. Optimizing Antimicrobial Dosing in the Intensive Care Unit 13. Antibiotic within 1 hour: Should this be Applied to all Patients with Sepsis? 14. Dark Side of Antibiotics 15. Optimal Duration of Antibiotic Therapy 16. Cefiderocol: Is this the Answer to Multidrug-resistant Gram-negative Infection? SECTION 3: Respiratory Critical Care 17. Management of Pneumonia in Intensive Care 18. Reverse Triggering during Controlled Ventilation: A Frequent Dysynchrony with Various Consequences 19. Use of Multiplex Polymerase Chain Reaction in Pneumonia 20. Management of Complicated Pleural Effusion 21. Hepatic Hydrothorax 22. Submassive Pulmonary Embolism 23. Role of Magnesium in Respiratory Failure 24. ARDS in Children: How is it Different? 25. Safe Tracheal Intubation in Intensive Care Unit 26. Lateral Positioning: Does it Work? 27. Dyspnea in Patients on Invasive Ventilation: Clinical Impact 28. Complications of Noninvasive Ventilation Failure SECTION 4: Mechanical Ventilation 29. Setting Optimum PEEP 30. Open Lung or Keep Lung Closed: Which Strategy to Choose? 31. Driving Pressure or Mechanical Power: Which One to Monitor? 32. Measuring Respiratory Drive and Muscle Effort 33. Oxygenation Targets in Mechanically Ventilated Critically-ill Patients 34. Ventilatory Ratio: A New Monitoring Tool 35. Helmet NIV: Is it a Game Changer? 36. Electrical Impedance Tomography: Current Application 37. Automatic Tube Compensation: Does it have a Role? 38. High-frequency Oscillatory Ventilation in Pediatric Acute Respiratory Distress Syndrome 39. Noninvasive Ventilation in Pediatrics: Current Status SECTION 5: Cardiovascular Critical Care 40. Crystalloid Resuscitation: Finding the Balance 41. Artificial Intelligence Tools to Optimize Hemodynamics in the ICU 42. Aggressive or Restrictive Fluid Resuscitation 43. Predicting Hypotension: Is It Useful? 44. Vasopressors: How Early? 45. Myocardial Injury after Noncardiac Surgery 46. Use of Vasopressin during Cardiac Arrest SECTION 6: Echocardiography and Ultrasound 47. Advances in Intensive Care Unit Echocardiography 48. Transesophageal Echocardiography: Is It Preferable in the Intensive Care Unit? 49. ECHO Features of Pulmonary Hypertension and Increased Left Atrial Pressures 50. Role of Echocardiography in Shock State 51. Use of Echocardiography in Assessing Fluid Responsiveness 52. Venous Excess Ultrasound Score (VExUS) SECTION 7: Nephrology, Fluids, Acid-Base Balance and Electrolytes Balance 53. Fluid Management in Acute Kidney Injury 54. Sepsis-associated Acute Kidney Injury: Common but Poorly Understood 55. Delayed versus Very Delayed Renal Replacement Therapy 56. Plasma Exchange in Intensive Care Unit: Current Status 57. Acute Kidney Injury Care Bundle 58. Biomarker-driven Therapy in AKI 59. How to Approach Dyselectrolytemias in a Patient on CRRT? SECTION 8: Neurocritical Care 60. Prognostication in
In the last decade, researchers working in the field of cancer biology have shifted their focus from genetic defects to epigenetic dysregulation, especially that of non-coding RNAs (ncRNAs). This book encompasses a comprehensive review of the transcriptional landscape of the cell and its involvement in the cancer pathophysiology. The first two chapters elucidate the basics of biosynthesis, mechanism of action and modulation of the epigenetic regulation of gene expression by coding as well as non-coding RNAs. The third chapter discusses the aberrant expression of the cellular RNome in the cancer cells and highlights its role in the orchestration of processes involved in evolution as well as the sustenance of cancer cells. The fourth chapter describes the recent advances in the field of translating the transcriptome into diagnostic/prognostic biomarkers and as targets for novel anti-cancer therapies. The final chapter then reviews the emerging experimental approaches to screen, identify and explore the functions of ncRNAs. Providing valuable insights into the field of RNome in the context of cancer, this book is helpful to students, researchers and clinicians..
Handbook of Analytical Techniques for Forensic Samples: Current and Emerging Developments discusses in detail the current trends and latest analytical techniques and methods commonly employed in forensic analysis in order to ensure the proper facilitation of justice. This book is useful for readers who wish to stay updated on the latest trends in the forensic analysis of samples encountered at crime scenes. Technological advancements, such as biosensors, nanotechnology, and taggant technology have upped the level of analysis in forensic science. These emergent technologies, incorporated with existing analytical techniques, are leading to more precise, accurate, and specific examination of forensic samples. Lab-on-a-chip technology has also eased several kinds of on-site analyses done by investigating teams at different types of crime scenes. This book covers the evolution of forensic sample analysis as well as these emerging trends and new technologies. - Includes an entire section of experimental exercises for self-teaching and key concept review - Covers laboratory protocols used in forensic science laboratories for the analysis of various samples through different analytical techniques - Condenses the many aspects of forensic analytical chemistry into a single resource with easy-to-understand language for everyone from students to practitioners
China and India have in recent years seen a change in leadership, with each wanting to make an impact on their respective societies by bringing about significant changes in governance. This book looks at the impact of major institutional disruptions on large-, medium- and small-sized enterprises in China and India. The book endeavours to systematically assess the impact of major institutional policy changes that seek to transform and overhaul the status quo at institutional, social and business levels. It also provides a holistic understanding of the impact of a major and turbulent policy shift on Asia’s two giant economies. This book is a must-read for those interested in gaining insights into the two dominant powers in Asia.
This book takes a holistic approach to explore how business is being conducted in China and India, and to analyze the factors that influence business decisions in present times. In doing so the book seeks to develop a fuller understanding of the present ‘context’ within the two Asian nations, drawing upon a complete understanding of the culture, history and behaviour of the society and its institutions. The authors probe an area that has not been widely addressed before and seek to provide a finer analysis of the influences behind day-to-day business operations. This study has widespread appeal as it covers business processes at three different levels: macro-level, including government policies and institutions; meso-level, organisations and communities; and micro-level, individuals within business. Not only appealing to scholars, senior executives, business professionals and policy-makers, this book will also provide an interdisciplinary examination of how business is conducted in China and India, and will be valuable to anyone with a general interest in Asian business.
This book provides a summarized information related to the global herbal drug market and its regulations, ethnopharmacology of traditional crude drugs, isolation of phytopharmaceuticals, phytochemistry, standardization, and quality assessment of crude drugs. Natural products science has constantly been developing with comprehensive data contemplating different parts of natural drugs, such as global trade, quality control and regulatory concerns, traditional medicine systems, production and utilization of drugs, and utilization of medicinal and aromatic plants. This broad information about crude drugs gives rise to a subject that is now recognized as advance natural products science. By contemplating all of this thorough knowledge of the areas, this book is intended to provide considerably to the natural products science. The area of natural products science involves a broad range of topics, such as the pharmacognostical, phytochemical, and ethno-pharmacological aspects of crude drugs. Each chapter gives a sufficient understanding to academicians and researchers in the respective topic. This book includes 40 illustrations and descriptions of roughly 80 medicinal plants used for herbal medicine. The book is an imperative source for all researchers, academicians, students, and those interested in natural products science. FEATURES Includes advance knowledge and detailed developments in natural products science Discusses the most important phytopharmaceuticals used in the pharmaceutical industry Explores the analysis and classification of novel plant-based medicinal compounds Includes standardization, quality control, and global trade of natural products Gives a deep understanding related to recent advances in herbal medicines to treat various ailments Discusses national and WHO regulations and policies related to herbal medicines Covers the complete profile of some important traditional medicinal plants, especially their historical background, biology, and chemistry
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