When seeking to test specific hypotheses in large data sets, social and behavioral scientists often construct models. Although useful in such situations, many phenomena of interest do not occur in large samples and do not lend themselves to precise measurement. In addition, a focus on hypothesis testing can constrict the potential use of models as organizing devices for emerging patterns -- summaries of what we believe we know about the dynamics of situation. This book bridges the gap between "quantitative" and "qualitative" modelers to reconcile the need to impose rigor and to understand the influence of context. Although there are many different uses for models, there is also the realistic possibility of doing credible research without their use. A critical reexamination of the assumptions used in quantitatively-oriented models, however, suggests ways to increase their effectiveness as organizers of both quantitative and qualitative data. Students of methods in psychology, sociology, education, management, social work, and public health -- and their instructors -- are increasingly expected to become familiar with both quantitative and qualitative approaches. Unfortunately, they find few vehicles for communication regarding the implications of overlapping work between the two approaches. Using models as organizing devices for a better dialogue between assumptions and data might facilitate this communication process.
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic chemistry and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background* Contains twice the number of chapters of the first edition* Each chapter contains boxes of information on topics of general interest
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain.* Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. * Thousands of literature references provide introduction to current research as well as historical background * Contains twice the number of chapters of the first edition * Each chapter contains boxes of information on topics of general interest
The new gold-standard in anesthesiology Written and edited by an internationally known team of experts, Anesthesiology gives you a 360-degree view of the field, covering all of the anesthetic considerations, preparations, and procedures for the surgical patient, the pain patient or the critical care patient. You'll find a unique balance between clinical information, practical clinical procedures, and the molecular and basic scientific underpinnings of anesthesiology practice. Anesthesiology delivers a multi-perspective, wide-ranging view of anesthetic drugs, procedures, co-morbid diseases, and need-to-know postoperative pain management strategies. This essential guide not only focuses on general anesthesia, but also is the first to feature a detailed look at the subspecialty of regional anesthesia. Features: Top-to-bottom coverage of the entire field-from preoperative evaluation and intraoperative anesthesia care to care of the critically ill or chronic pain patient Emphasis on safety, quality and patient-centered care, with an entire section on risk reduction A focus on the clinical applications of anesthesiology Complex concepts explained by graphics and illustrations, not equations and formulas Full-color format and illustrations Specific drug and interventional guidelines for the clinical management of every OR/post-OR scenario in the anesthesiology field Key points and key references presented in each chapter CD that allows you to download illustrations and images to your PowerPoint presentations
An engrossing examination of the science behind the little-known world of sleep. Like many of us, journalist David K. Randall never gave sleep much thought. That is, until he began sleepwalking. One midnight crash into a hallway wall sent him on an investigation into the strange science of sleep. In Dreamland, Randall explores the research that is investigating those dark hours that make up nearly a third of our lives. Taking readers from military battlefields to children’s bedrooms, Dreamland shows that sleep isn't as simple as it seems. Why did the results of one sleep study change the bookmakers’ odds for certain Monday Night Football games? Do women sleep differently than men? And if you happen to kill someone while you are sleepwalking, does that count as murder? This book is a tour of the often odd, sometimes disturbing, and always fascinating things that go on in the peculiar world of sleep. You’ll never look at your pillow the same way again.
Provide optimal anesthetic care to your young patients with A Practice of Anesthesia in Infants and Children, 5th Edition, by Drs. Charles J. Cote, Jerrold Lerman, and Brian J. Anderson. 110 experts representing 10 different countries on 6 continents bring you complete coverage of the safe, effective administration of general and regional anesthesia to infants and children - covering standard techniques as well as the very latest advances. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Find authoritative answers on everything from preoperative evaluation through neonatal emergencies to the PACU. Get a free laminated pocket reference guide inside the book! Quickly review underlying scientific concepts and benefit from expert information on preoperative assessment and anesthesia management, postoperative care, emergencies, and special procedures. Stay on the cutting edge of management of emergence agitation, sleep-disordered breathing and postoperative vomiting; the use of new devices such as cuffed endotracheal tubes and new airway devices; and much more. Familiarize yourself with the full range of available new drugs, including those used for premedication and emergence from anesthesia. Benefit from numerous new figures and tables that facilitate easier retention of the material; new insights from neonatologists and neonatal pharmacologists; quick summaries of each chapter; and more than 1,000 illustrations that clarify key concepts. Access the entire text online, fully searchable, at www.expertconsult.com, plus an extensive video library covering simulation, pediatric airway management, burn injuries, ultra-sound guided regional anesthesia, and much more; and new online-only sections, tables and figures.
Ion channels are crucial components of living cells. Situated in the cell's membranes. they allow particular ions to pass from one side of the membrane to the other. In recent years the patch clamp technique has allowed the activity of individual channels to be measured, and recombinant DNA technology has led to fascinating detail on their structure. Together, these technical advances have produced a great flowering of knowledge and understanding about the subject, itself leading to further breakthroughs in science and medicine. Ion Channels provides an introduction to this scientific endeavour. It emphasises the molecular structure of channels as determined by gene cloning technology. This knowledge illuminates discussions of the permeability and selectivity of channels, their gating and modulation, their responses to drugs and toxins and the human diseases caused when they do not function properly.
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