David Van Etten's Books

Molecular and Cellular Therapeutics

By: David Whitehouse,Ralph Rapley

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Molecular and Cellular Therapeutics

By: David Whitehouse,Ralph Rapley

Molecular and Cellular Therapeutics aims to bring together key developments in the areas of molecular diagnostics, therapeutics and drug discovery. The book covers topics including diagnostics, therapeutics, model systems, clinical trials and drug discovery. The developing approaches to molecular and cellular therapies, diagnostics and drug discovery are presented in the context of the pathologies they are devised to treat.

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Page Count

331

Publisher

John Wiley & Sons

Published Date

ISBN 10

0470748141

ISBN 13

9780470748145

Digital Communication

By: John R. Barry,Edward A. Lee,David G. Messerschmitt

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Digital Communication

By: John R. Barry,Edward A. Lee,David G. Messerschmitt

This book concerns digital communication. Specifically, we treat the transport of bit streams from one geographical location to another over various physical media, such as wire pairs, coaxial cable, optical fiber, and radio. We also treat multiple-access channels, where there are potentially multiple transmitters and receivers sharing a common medium. Ten years have elapsed since the Second Edition, and there have been remarkable advances in wireless communication, including cellular telephony and wireless local-area networks. This Third Edition expands treatment of communication theories underlying wireless, and especially advanced techniques involving multiple antennas, which tum the traditional single-input single-output channel into a multiple-input multiple-output (MIMO) channel. This is more than a trivial advance, as it stimulates many advanced techniques such as adaptive antennas and coding techniques that take advantage of space as well as time. This is reflected in the addition of two new chapters, one on the theory of MIMO channels, and the other on diversity techniques for mitigating fading. The field of error-control coding has similarly undergone tremendous changes in the past decade, brought on by the invention of turbo codes in 1993 and the subsequent rediscovery of Gallager's low-density parity-check codes. Our treatment of error-control coding has been rewritten to reflect the current state of the art. Other materials have been reorganized and reworked, and three chapters from the previous edition have been moved to the book's Web site to make room.

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843

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1461502276

ISBN 13

9781461502272

The Unified Learning Model

How Motivational, Cognitive, and Neurobiological Sciences Inform Best Teaching Practices

By: Duane F. Shell,David W. Brooks,Guy Trainin,Kathleen M. Wilson,Douglas F. Kauffman,Lynne M. Herr

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The Unified Learning Model

How Motivational, Cognitive, and Neurobiological Sciences Inform Best Teaching Practices

By: Duane F. Shell,David W. Brooks,Guy Trainin,Kathleen M. Wilson,Douglas F. Kauffman,Lynne M. Herr

This is a book about how humans learn. Our focus is on classroom learning although the principles are, as the name of this book indicates, universal. We are concerned with learning from pre-school to post-graduate. We are concerned with most bu- ness, industrial and military training. We do not address how infants learn how to speak or walk, or how grown-ups improve their tennis swing. We do address all learning described by the word “thought”, as well as anything we might try to teach, or instruct in formal educational settings. In education, the words theory and model imply conjecture. In science, these same words imply something that is a testable explanation of phenomena able to predict outcomes of experiments. This book presents a model of learning that the authors offer in the sense of scientists rather than educators. Conjecture implies that information is incomplete, and so it surely is with human learning. On the other hand, we assert that more than enough is known to sustain a “scienti?c” model of learning. This book is not a review of the literature. Instead, it is a synthesis. Scholars and many teachers likely have heard much if not most or even all of the information we use to develop the uni?ed learning model. What you have not read before is a model putting the information together in just this way; this is the ?rst one.

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211

Publisher

Springer Science & Business Media

Published Date

ISBN 10

9048132169

ISBN 13

9789048132164

Likely Story: Red Carpet Riot

By: David Van Etten

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Likely Story: Red Carpet Riot

By: David Van Etten

It’s award night—will Mallory make it down the red carpet? When we last left Mallory, her first show had just aired to rave ratings; her conniving mother was engaged to her dreaded producer boyfriend, Richard; she wasn’t sure if her boyfriend, Keith, would stick by her; and the school secretary had some unwelcome news about her student status. Now, just when her show gets a Daytime Emmy nomination, she’s got to fend off sneaky saboteurs, decide between Keith and Dallas, her show’s hunky star, break off her mother’s engagement, and pass gym class! Hang on for a wild ride that takes us to the end of Mallory’s story, and maybe her rope, as the Emmy Awards inch closer and closer and she’s got to do-sido as fast as she can to keep up.

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Page Count

306

Publisher

Knopf Books for Young Readers

Published Date

ISBN 10

0375853561

ISBN 13

9780375853562

Targeting Protein Kinases for Cancer Therapy

By: David J. Matthews,Mary E. Gerritsen

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Targeting Protein Kinases for Cancer Therapy

By: David J. Matthews,Mary E. Gerritsen

An expert guide to targeting protein kinases in cancer therapy Research has shown that protein kinases can instigate the formation and spread of cancer when they transmit faulty signals inside cells. Because of this fact, pharmaceutical scientists have targeted kinases for intensive study, and have been working to develop medicinal roadblocks to sever their malignant means of communication. Complete with full-color presentations, Targeting Protein Kinases for Cancer Therapy defines the structural features of protein kinases and examines their cellular functions. Combining kinase biology with chemistry and pharmacology applications, this book enlists emerging data to drive the discovery of new cancer-fighting drugs. Valuable information includes: Comprehensive overviews of the major kinase families involved in oncology, integrating protein structure and function, and providing important tools to assist pharmaceutical researchers to understand and work in this dynamic area of cancer drug research Focus on small molecule inhibitors as well as other therapeutic modalities Discussion of kinase inhibitors that have entered clinical trials for the treatment of cancer, with an emphasis on molecules that have progressed to late stage clinical trials and, in a few cases, to market Providing a platform for further study, this important work reviews both the successes and challenges of kinase inhibitor therapy, and provides insight into future directions in the war against cancer.

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719

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118210778

ISBN 13

9781118210772

Diet-Related Diseases

The Modern Epidemic

By: Stephen Seely,David L. J. Freed,Gerald A. Silverstone,Vicky Rippere

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Diet-Related Diseases

The Modern Epidemic

By: Stephen Seely,David L. J. Freed,Gerald A. Silverstone,Vicky Rippere

Originally published in 1985, and authored by an epidemiologists, a medical immunologist, a chemist and a clinical psychologist, this books shows that unravelling the links between diet and disease is a very complex task, and while the evidence is strong in many cases, in others if is of doubtful validity. Many of the diseases prevalent in developed countries are discussed here: cancer, arterial heart disease, food allergies and intolerances as well as the impact of diet on mental health.

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256

Publisher

Routledge

Published Date

ISBN 10

1000577953

ISBN 13

9781000577952

Fields Virology: Fundamentals

By: Peter M Howley,David M Knipe,Lynn W Enquist

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Fields Virology: Fundamentals

By: Peter M Howley,David M Knipe,Lynn W Enquist

Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families.

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Page Count

1999

Publisher

Lippincott Williams & Wilkins

Published Date

ISBN 10

1975112520

ISBN 13

9781975112523

Freshwater Microbiology

Biodiversity and Dynamic Interactions of Microorganisms in the Aquatic Environment

By: David C. Sigee

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Freshwater Microbiology

Biodiversity and Dynamic Interactions of Microorganisms in the Aquatic Environment

By: David C. Sigee

This unique textbook takes a broad look at the rapidly expanding field of freshwater microbiology. Concentrating on the interactions between viruses, bacteria, algae, fungi and micro-invertebrates, the book gives a wide biological appeal. Alongside conventional aspects such as phytoplankton characterisation, seasonal changes and nutrient cycles, the title focuses on the dynamic and applied aspects that are not covered within the current textbooks in the field. Complete coverage of all fresh water biota from viruses to invertebrates Unique focus on microbial interactions including coverage of biofilms, important communities on all exposed rivers and lakes. New information on molecular and microscopical techniques including a study of gene exchange between bacteria in the freshwater environment. Unique emphasis on the applied aspects of freshwater microbiology with particular emphasis on biodegradation and the causes and remediation of eutrophication and algal blooms.

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516

Publisher

John Wiley & Sons

Published Date

ISBN 10

0470026472

ISBN 13

9780470026472

Making Mountains

New York City and the Catskills

By: David Stradling

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Making Mountains

New York City and the Catskills

By: David Stradling

For over two hundred years, the Catskill Mountains have been repeatedly and dramatically transformed by New York City. In Making Mountains, David Stradling shows the transformation of the Catskills landscape as a collaborative process, one in which local and urban hands, capital, and ideas have come together to reshape the mountains and the communities therein. This collaboration has had environmental, economic, and cultural consequences. Early on, the Catskills were an important source of natural resources. Later, when New York City needed to expand its water supply, engineers helped direct the city toward the Catskills, claiming that the mountains offered the purest and most cost-effective waters. By the 1960s, New York had created the great reservoir and aqueduct system in the mountains that now supplies the city with 90 percent of its water. The Catskills also served as a critical space in which the nation's ideas about nature evolved. Stradling describes the great influence writers and artists had upon urban residents - especially the painters of the Hudson River School, whose ideal landscapes created expectations about how rural America should appear. By the mid-1800s, urban residents had turned the Catskills into an important vacation ground, and by the late 1800s, the Catskills had become one of the premiere resort regions in the nation. In the mid-twentieth century, the older Catskill resort region was in steep decline, but the Jewish "Borscht Belt" in the southern Catskills was thriving. The automobile revitalized mountain tourism and residence, and increased the threat of suburbanization of the historic landscape. Throughout each of these significant incarnations, urban and rural residents worked in a rough collaboration, though not without conflict, to reshape the mountains and American ideas about rural landscapes and nature.

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362

Publisher

University of Washington Press

Published Date

ISBN 10

0295989890

ISBN 13

9780295989891

Likely Story (Book 1)

By: David Van Etten

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Likely Story (Book 1)

By: David Van Etten

MALLORY IS A teenage girl living in L.A. and her mother is the oftnominated, never-winning star of a daytime soap; she is, in fact, the ultimate drama queen. After yet another blow-out about her mother’s awful plotlines and overacting, Mallory starts blogging about how she wishes soap operas were more like real kids’ lives instead of the ridiculous storylines the shows usually feature. When her mother’s agent reads the blog, Mallory ends up in her own whirlwind drama, both at school and on the lot, as she works to protect the integrity of her original idea, cope with her mother’s jealousy, and get her best friend a lead role on the show. Factor in her boyfriend with the girlfriend, the cute but bad brother to said-best-friend, and the super-cute male lead on her show, and Mallory’s got plenty of her own melodrama to cope with.

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242

Publisher

Knopf Books for Young Readers

Published Date

ISBN 10

0375849629

ISBN 13

9780375849626

Chemical Signals in Vertebrates 4

Ecology, Evolution, and Comparative Biology

By: David Duvall,Dietland Müller-Schwarze,Robert M. Silverstein

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Chemical Signals in Vertebrates 4

Ecology, Evolution, and Comparative Biology

By: David Duvall,Dietland Müller-Schwarze,Robert M. Silverstein

This volume reviews recent developments in our understanding of che~ ical signaling in vertebrates. After sections dealing with general princi ples and chemical aspects of vertebrate pheromones, it follows a taxonomic approach, progressing from fish to. mammals. The editors asked a diverse, international group of leading investigators, working on a wide array of vertebrate taxa and specific issues, to consider their efforts from compar ative, evolutionary, and ecological viewpoints. The relative number of manuscripts in each part does not necessarily reflect current intensity of research, since the editors invited speakers who together would provide a balanced and comprehensive overview, while avoiding duplication. Still, the part on mammals is the longest. Fourth in a series dating from 1977, this volume illuminates current trends and likely future developments in the field of chemical signaling in vertebrates. Going back even farther, the first chapter, a personal account of the past quarter century by Dr. Mykytowycz recalls the most important milestones, such as symposia, or the founding of societies and journals. He also credits those investigators who stand out by their seminal studies.

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728

Publisher

Springer Science & Business Media

Published Date

ISBN 10

1461322359

ISBN 13

9781461322351

Carbon Sequestration for Climate Change Mitigation and Adaptation

By: David A. N. Ussiri,Rattan Lal

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Carbon Sequestration for Climate Change Mitigation and Adaptation

By: David A. N. Ussiri,Rattan Lal

This book provides an understanding of the role of human activities in accelerating change in global carbon cycling summarizes current knowledge of the contemporary carbon budget. Starting from the geological history, this volume follows a multidisciplinary approach to analyze the role of human activities in perturbing carbon cycling by quantifying changes in different reservoirs and fluxes of carbon with emphasis on the anthropogenic activities, especially after the industrial revolution. It covers the role of different mitigation options – natural ecological, engineered, and geoengineered processes as well as the emerging field of climate engineering in avoiding dangerous abrupt climate change. Although the targeted audience is the educators, students, researchers and scientific community, the simplified analysis and synthesis of current and up to date scientific literature makes the volume easier to understand and a tool policy makers can use to make an informed policy decisions.

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554

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Springer

Published Date

ISBN 10

3319538454

ISBN 13

9783319538457

Psychopathology

History, Diagnosis, and Empirical Foundations

By: W. Edward Craighead,David J. Miklowitz,Linda W. Craighead

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Psychopathology

History, Diagnosis, and Empirical Foundations

By: W. Edward Craighead,David J. Miklowitz,Linda W. Craighead

Designed for graduate level courses in adult psychopathology, the Second Edition of this book incorporates the newly released (2013) DSM-5 . Unique in its approach, this text presents a historical context in which current diagnoses are made. Presenting an overview of the issues and methodologies of conducting assessments, each of the major psychological disorders is discussed in a standard format in the chapter dealing with that disorder. The text includes new chapters on nonalcohol substance abuse and contextual factors affecting diagnoses. Each chapter covers: description from DSM, using case examples; epidemiology; basic research, including neurobiology and neuroscience of the disorder; prevalence and consequences of the disorder; behavioral, social, cognitive, and emotional aspects of the disorder; and treatment of the disorder, using clinical examples showing how psychopathology and assessment influence treatment"--

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736

Publisher

John Wiley & Sons

Published Date

ISBN 10

1118106776

ISBN 13

9781118106778

A History of the Rutgers University Glee Club

By: David F. Chapman

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A History of the Rutgers University Glee Club

By: David F. Chapman

Founded in 1872, the Glee Club is Rutgers University’s oldest continuously active student organization, as well as one of the first glee clubs in the United States. For the past 150 years, it has represented the university and presented an image of the Rutgers man on a national and international stage. This volume offers a comprehensive history of the Rutgers Glee Club, from its origins adopting traditions from the German Männerchor and British singing clubs to its current manifestation as a world-recognized ensemble. Along the way, we meet the colorful and charismatic men who have directed the group over the years, from the popular composer and minstrel performer Loren Bragdon to the classically-trained conductor Patrick Gardner. And of course, we learn what the club has meant to the generations of talented and dedicated young men who have sung in it. A History of the Rutgers University Glee Club recounts the origins of the group’s most beloved traditions, including the composition of the alma mater’s anthem “On the Banks of the Old Raritan” and the development of the annual Christmas in Carol and Song concerts. Meticulously researched, including a complete discography of the club’s recordings, this book is a must-have for all the Rutgers Glee Club’s many fans and alumni.

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328

Publisher

Rutgers University Press

Published Date

ISBN 10

1978832230

ISBN 13

9781978832237

Nucleic Acids and Molecular Biology

By: Fritz Eckstein,David M. J. Lilley

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Nucleic Acids and Molecular Biology

By: Fritz Eckstein,David M. J. Lilley

A wide range of topics are covered, including articles on nucleic acid structure, through their interactions with proteins to the control of gene expression. A number of authors address the subject of RNA, including the difficult but important subject of its chemical synthesis, the complexities of its structures and the mechanisms of transcript splicing. The probing of DNA structure is reviewed in papers on the application of hydroxyl radical and 1,10 phenanthroline copper cleavages. A number of important DNA-protein interactions are discussed, including DNA polymerase, the tryptophan and deoR repressors, and the resolvase enzymes which cleave Holliday junctions in recombination. Gene transcription is also covered, from the points of view of DNA methylation, mammalian ribosomal and avian lysozyme genes, and the control of transcription in the proto-oncogene c-fos. Finally, the plant kingdom has not been forgotten with articles on development and transposition in plants.

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281

Publisher

Springer Science & Business Media

Published Date

ISBN 10

3642837093

ISBN 13

9783642837098

Phased Arrays for Radio Astronomy, Remote Sensing, and Satellite Communications

By: Karl F. Warnick,Rob Maaskant,Marianna V. Ivashina,David B. Davidson,Brian D. Jeffs

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Phased Arrays for Radio Astronomy, Remote Sensing, and Satellite Communications

By: Karl F. Warnick,Rob Maaskant,Marianna V. Ivashina,David B. Davidson,Brian D. Jeffs

Discover a modern approach to the analysis, modeling and design of high sensitivity phased arrays. Network theory, numerical methods and computational electromagnetic simulation techniques are uniquely combined to enable full system analysis and design optimization. Beamforming and array signal processing theory are integrated into the treatment from the start. Digital signal processing methods such as polyphase filtering and RFI mitigation are described, along with technologies for real-time hardware implementation. Key concepts from interferometric imaging used in radio telescopes are also considered. A basic development of theory and modeling techniques is accompanied by problem sets that guide readers in developing modeling codes that retain the simplicity of the classical array factor method while incorporating mutual coupling effects and interactions between elements. Combining current research trends with pedagogical material suitable for a first-year graduate course, this is an invaluable resource for students, teachers, researchers, and practicing RF/microwave and antenna design engineers.

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471

Publisher

Cambridge University Press

Published Date

ISBN 10

1108540287

ISBN 13

9781108540285

Anticancer

A New Way of Life

By: David Servan-Schreiber

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Anticancer

A New Way of Life

By: David Servan-Schreiber

The author describes his treatment for brain cancer, challenges beliefs about the body's ability to heal, identifies the environmental and lifestyle factors that promote cancer growth, and outlines conventional and alternative therapies.

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321

Publisher

Penguin Group

Published Date

ISBN 10

0670020346

ISBN 13

9780670020348

The Instinct to Heal

Curing Depression, Anxiety and Stress Without Drugs and Without Talk Therapy

By: David Servan-Schreiber, MD, PhD

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The Instinct to Heal

Curing Depression, Anxiety and Stress Without Drugs and Without Talk Therapy

By: David Servan-Schreiber, MD, PhD

Millions of Americans try drugs or talk therapy to relieve depression and anxiety, but recent scientific studies prove certain alternative treatments can work as well or better-often bringing on a cure. In the extraordinary international bestseller The Instinct to Heal, award-winning psychiatrist and neuroscientist David Servan-Schreiber, M.D., Ph.D., presents seven natural approaches, each with proven results, that together form a treatment plan that builds on the body's relationship to the brain, yielding faster, more dramatic, and permanent changes. People who want to leave suffering behind now can live joyful, happy lives.

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292

Publisher

Rodale Books

Published Date

ISBN 10

1594869006

ISBN 13

9781594869006

Treatment of Leukemia and Lymphoma

By: David A. Scheinberg,Joseph G. Jurcic

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Treatment of Leukemia and Lymphoma

By: David A. Scheinberg,Joseph G. Jurcic

New Treatments of Leukemia and Lymphoma describes the most important advances in the therapy of hematopoietic cancers that have been derived from recent discoveries in cancer cell biology, kinase biochemistry, and immunology. Detailed descriptions of the large number of new and effective agents that have recently become available for the treatment of leukemias and lymphomas as well as an understanding of their mechanisms of action and their integration into current therapy are provided. A number of experimental drug reagents currently in clinical investigation are also discussed. The therapies include conventional anti-metabolites, monoclonal antibodies directed to cell surface receptors, antibodies tagged with toxins and radiopharmaceuticals, inhibitors of specific kinases, stem cell transplants, and engineered T-cells designed to selectively target hematopoietic cancers. The contents of the book will allow practitioners and investigators alike to understand what is current and state of the art as well as what to look for in the future.* Provides an up-to-date, state of the art discussion of a rapidly changing field * Great breadth covering conventional chemotherapeutic agents, biologic agents such as antibodies, novel small molecule inhibitors and genetically engineered cells * Written by international experts in each of the fields

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417

Publisher

Elsevier

Published Date

ISBN 10

0080490409

ISBN 13

9780080490403

Fungal Physiology

By: David H. Griffin

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Fungal Physiology

By: David H. Griffin

Thoroughly revised, this edition summarizes the field of fungal physiology from a dynamic, experimental perspective. Integrates molecular genetics with biochemistry and development of fungi. Reorganized into 14 chapters it describes the latest contemporary experimental approaches to fungal research as well as future developments.

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476

Publisher

John Wiley & Sons

Published Date

ISBN 10

0471166154

ISBN 13

9780471166153

Oncology of Infancy and Childhood E-Book

By: Stuart H. Orkin,David E. Fisher,A. Thomas Look,Samuel Lux,David Ginsburg,David G. Nathan

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Oncology of Infancy and Childhood E-Book

By: Stuart H. Orkin,David E. Fisher,A. Thomas Look,Samuel Lux,David Ginsburg,David G. Nathan

To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes. With this volume devoted strictly to pediatric oncology, and another to pediatric hematology, you will be on the cutting edge of these two fields. This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. Written by the leading names in pediatric oncology, this resource is an essential tool for all who care for pediatric cancer patients. Offers comprehensive coverage of all pediatric cancers, including less common tumors, making this the most complete guide to pediatric cancer. Covers emerging research developments in cancer biology and therapeutics, both globally and in specific pediatric tumors. Includes a section on supportive care in pediatric oncology, written by authors who represent the critical subdisciplines involved in this important aspect of pediatric oncology. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines. Presents a full-color design that includes clear illustrative examples of the relevant pathology and clinical issues, for quick access to the answers you need. Incorporates the codified WHO classification for all lymphomas and leukemias.

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1387

Publisher

Elsevier Health Sciences

Published Date

ISBN 10

1437721389

ISBN 13

9781437721386

Men and Style

Essays, Interviews and Considerations

By: David Coggins

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Men and Style

Essays, Interviews and Considerations

By: David Coggins

New York Times Bestseller Men and Style reaches beyond standard “what to wear” advice: It is equal parts style guide and intriguing conversation about the masculine identity within the world of fashion. David Coggins explores the history of men’s style and learns from some of the most notable tastemakers in the industry and beyond. Its essays and interviews discuss the lessons men learned from their fathers, the mistakes they made as young men, and how they emerged to become better men. Some of the most dapper men in the world discuss bad mustaches, misguided cologne choices, and unfortunate prom tuxedos. All the men here have arrived at a place in the world and have a keen understanding about how they fit in it. Men and Style celebrates singular men who’ve lived well and can tell us about how they earned their worldview. They’re smart enough to absorb the wisdom that’s hidden in the world, and even smarter to wear that wisdom lightly.

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404

Publisher

Abrams

Published Date

ISBN 10

1613122373

ISBN 13

9781613122372

From Abyssinian to Zion

A Guide to Manhattan's Houses of Worship

By: David W. Dunlap

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From Abyssinian to Zion

A Guide to Manhattan's Houses of Worship

By: David W. Dunlap

Published in conjunction with a New York Historical Society exhibition, this photo-filled, pocket-sized guidebook by a "New York Times reporter covers 1,079 houses of worship in New York City. 899 photos & 24 maps.

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472

Publisher

Columbia University Press

Published Date

ISBN 10

0231125437

ISBN 13

9780231125437

The Designer's Guide to Jitter in Ring Oscillators

By: John A. McNeill,David Ricketts

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The Designer's Guide to Jitter in Ring Oscillators

By: John A. McNeill,David Ricketts

This guide emphasizes jitter for time domain applications so that there is not a need to translate from frequency domain. This provides a more direct path to the results for designing in an application area where performance is specified in the time domain. The book includes classification of oscillator types and an exhaustive guide to existing research literature. It also includes classification of measurement techniques to help designers understand how the eventual performance of circuit design is verified.

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292

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Springer Science & Business Media

Published Date

ISBN 10

038776528X

ISBN 13

9780387765280

Handbook of Chronic Myeloid Leukemia

By: Timothy P Hughes,David M Ross,Junia V Melo

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Handbook of Chronic Myeloid Leukemia

By: Timothy P Hughes,David M Ross,Junia V Melo

This concise, clinically focused pocket handbook assembles and synthesizes the latest developments and trends in the diagnosis and treatment of CML and provides an authoritative and convenient summary of the latest progress in TKI trials, the molecular monitoring of CML responses, and the development of new therapies to overcome resistance and improve patient care. Chronic myeloid leukemia (CML) is a rare type of leukemia (1–2 per 100,000 people) but is the most common chronic myeloproliferative neoplasm. CML remains a key model for the improved understanding of the pathophysiology of a malignancy at a molecular level; CML was the first cancer to be associated with a recurring chromosome abnormality, which generates the Philadelphia (Ph) chromosome and its associated fusion gene BCR-ABL1. The clinical outcome for patients with CML has changed dramatically in the past 15 years and this has been due to the development of tyrosine kinase inhibitors (TKIs), compounds that inhibit the activity of the oncogenic BCR-ABL1 protein. A number of first-, second- and third-generation TKIs are now available for the treatment of CML, although a number of treatment challenges remain, not least the development of treatment-resistant CML. Parallel to the development of specific drugs for treating CML, major advances have been made in the field of disease monitoring and standardization of response criteria.

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Springer

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ISBN 10

3319083503

ISBN 13

9783319083506

The Ascended Masters Light the Way

Beacons of Ascension

By: Joshua David Stone

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The Ascended Masters Light the Way

Beacons of Ascension

By: Joshua David Stone

This book is dedicated to the saints and spiritual masters of all the religions and spiritual paths that have graced this planet. The lives and teachings of thirty-nine of the world's greatest spiritual beacons provide a blueprint for total self-realization. Inspiring guidance from those who have learned the secrets of mastery in their lifetimes.

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Page Count

292

Publisher

Light Technology Publishing

Published Date

ISBN 10

0929385586

ISBN 13

9780929385587

Book's by David Van Etten

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